Urinary hepcidin excretion in patients with low grade myelodysplastic syndrome

British Journal of Haematology

Volumn 144, Issue 3, 2009, Pages 451-452

  Murphy, P T ^a   Mitra, S ^a   Gleeson, M ^a   Desmond, R ^a   Swinkels, D W ^b  

^a BEAUMONT HOSPITAL   (Ireland)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Functional iron deficiency; Hepcidin; Myelodysplastic syndrome; Percentage hypochromic red cells; Red cell zinc protoporphyrin

Indexed keywords

HEPCIDIN; PROTOPORPHYRIN ZINC;

DYSPLASIA; ERYTHROCYTE; HUMAN; IRON DEFICIENCY; LETTER; MASS SPECTROMETRY; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROTEIN URINE LEVEL; REFRACTORY ANEMIA; REFRACTORY CYTOPENIA WITH MULTILINEAGE DYSPLASIA; SIDEROBLASTIC ANEMIA; URINARY EXCRETION;

ADULT; AGED; AGED, 80 AND OVER; ANTIMICROBIAL CATIONIC PEPTIDES; CASE-CONTROL STUDIES; FEMALE; FERRITINS; HUMANS; IRON OVERLOAD; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; RISK; YOUNG ADULT;

EID: 58449093745     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.07455.x     Document Type: Letter

References (6)

1. Kemna, E.H.J.M., Tjalsma, H., Podust, V.N. Swinkels, D.W. (2007) Mass spectrometry-based hepcidin measurements in serum and urine: analytical aspects and clinical implications. Clinical Chemistry, 53, 620 628.
2. Murphy, P.T., Quinn, J.P., O'Donghaile, D., Swords, R. O'Donnell, J.R. (2006) Myelodysplastic patients with raised percentage of hypochromic red cells have evidence of functional iron deficiency. Annals of Hematology, 85, 455 457.
3. Peyssonnaux, C., Zinkernagel, A.S., Schuepbach, R.A., Rankin, E., Vaulont, S., Hasse, V.H., Nizet, V. Johnson, R.S. (2007) Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). Journal of Clinical Investigation, 117, 1926 1932.
4. Silvestri, L., Pagani, A. Camaschella, C. (2008) Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Blood, 111, 924 931.
5. Tanno, T., Bhanu, N.V., Oneal, P.A., Goh, S.H., Staker, P., Lee, Y.T., Moroney, J.W., Reed, C.H., Luban, N.L., Wang, R.H., Eling, T.E., Childs, R., Ganz, T., Leitman, S.F., Fucharoen, S. Miller, J.L. (2007) High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nature Medicine, 13, 1096 1101.
6. Winder, A., Lefkowitz, R., Ghoti, H., Leiba, M., Ganz, T., Nemeth, E. Rachmilewitz, E.A. (2008) Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis. British Journal of Haematology, 142, 669 671.