A single gene causes both male sterility and segregation distortion in Drosophila hybrids

Science

Volumn 323, Issue 5912, 2009, Pages 376-379

  Phadnis, Nitin ^a   Orr, H Allen ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EVOLUTIONARY BIOLOGY; FLY; GENE; HYBRID; REPRODUCTIVE ISOLATION; SELECTION; STERILITY; SUBSPECIES;

ARTICLE; CHROMOSOME; DROSOPHILA; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; HYBRID; MALE STERILITY; NONHUMAN; PRIORITY JOURNAL; REPRODUCTIVE ISOLATION; SEGREGATION DISTORTION; SPECIES DIFFERENTIATION;

ANIMALS; CARRIER PROTEINS; CHROMOSOME MAPPING; CHROMOSOME SEGREGATION; CROSSES, GENETIC; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE FLOW; GENES, INSECT; GENETIC SPECIATION; HYBRIDIZATION, GENETIC; INFERTILITY, MALE; MALE; MEIOSIS; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; SEX RATIO; TRANSGENES;

BOGOTA; COLOMBIA; NORTH AMERICA; SOUTH AMERICA; UNITED STATES;

DROSOPHILA PSEUDOOBSCURA;

EID: 58449091818     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1163934     Document Type: Article

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29. We thank C. Aquadro, J. Fry, R. Glor, H. Malik, D. Presgraves, Y. Tao, and the Orr lab for discussions; D. Lambert for advice on molecular techniques; H. Malik and N. Elde for help with PAML; and S. Schaeffer for fly stocks. Financial support was provided by NIH (GM51932). All sequences are available at GenBank (accession numbers FJ349335 to FJ349342 and FJ418600 to FJ418631). The authors declare no conflict of interest.