Hansen's disease in a general hospital: Uncommon presentations and delay in diagnosis

Journal of the European Academy of Dermatology and Venereology

Volumn 23, Issue 2, 2009, Pages 150-156

  Da Costa Nery, J A ^a   Schreuder, P A M ^b   Castro Teixeira De Mattos, P ^a   Vieira De Mendonca L ^a   Tebaldi Tardi, R ^c   De Mello, S ^b   Azulay, R D ^d   Lehman, L F ^b   Naafs, B ^e  

^a University Gama Filho   (Brazil)

^b NLR ^*

^c HD Control

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Delay in diagnosis; Hansen's disease; Leprosy; Uncommon presentation

Indexed keywords

ADULT; AGED; ANAMNESIS; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; GENERAL HOSPITAL; HOSPITAL ADMISSION; HUMAN; LABORATORY TEST; LEG ULCER; LEPROMATOUS LEPROSY; MALE; NEUROLOGIC EXAMINATION; PHYSICAL EXAMINATION; PHYSICIAN; PRIORITY JOURNAL; SKIN EXAMINATION;

ADULT; AGED; BRAZIL; FEMALE; HOSPITALS, GENERAL; HUMANS; LEPROSY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES;

EID: 58449086697     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2008.03006.x     Document Type: Article

References (45)

1. Nicholls PG, Croft RP, Richardus JH, Withington SG, Smith WCS. Delay in presentation, an indicator for nerve function status at registration and for treatment outcome - the experience of the Bangladesh Acute Nerve Damage Study cohort. Lepr Rev 2003 74 : 349 356.
2. Van Veen NHJ, Meima A, Richardus JH. The relationship between detection delay and impairment in leprosy control: a comparison of patient cohorts from Bangladesh and Ethiopia. Lepr Rev 2006 77 : 356 365.
3. Naafs B, Pearson JMH, Wheate HW. Reversal reaction: the prevention of permanent nerve damage. Comparison of short and long term steroid treatment. Int J Lepr 1979 47 : 7 12.
4. International Leprosy Association. Organization of Leprosy Services. Report of the ILA Technical Forum, France, February 2002. Int J Lepr 2002 70 (Suppl S53 S60.
5. Naafs B, v. Joost TH, Hausman R, v.d. Heide RM, de Vet BJCM. Een importziekte; een bijna gemiste diagnose. Ned Tijdschr Geneesk 1982 126 : 1897 1901.
6. v.d. Willigen AH, Chin-A-Lien RAM, v. Joost TH, Stolz E, Naafs B. Lepra, je moet er aan denken! Ned Tijdschr Geneesk 1989 133 : 1345 1347.
7. Lockwood DN, Reid AJ. The diagnosis of leprosy is delayed in the United Kingdom. QJM 2001 94 : 207 212.
8. Boggild AK, Keystone JS, Kain KC. Leprosy: a primer for Canadian physicians. CMAJ 2004 170 : 71 78.
9. Gill AL, Bell DR, Gill GV, Wyatt GB, Beeching NJ. Leprosy in Britain: 50 years experience in Liverpool. QJM 2005 98 : 505 511.
10. Buçard AM, Dias EO, Cherre DI et al. A necessidade do reconhecemento clínico da hanseníase na interdisciplinalidade médica. Abstract. II Congresso Internacional de Clínica Médica. São Paulo, Brasil, June 2004.
11. Ridley DS, Jopling WH. Classification of leprosy according to immunity. A five group system. Int J Lepr 1966 34 : 255 273.
12. World Health Organization. A Guide to Leprosy Control, 2nd edn. WHO, Geneva, 1988.
13. Leprosy (Hansen's disease). Epid Bull/ PAHO 2002 32 : 15 16.
14. Kawuma HJ. Buluba Leprosy Hospital, Uganda: a review of admissions. Lepr Rev 1987 58 : 257 262.
15. Prabhavalkar AB, Ansari K. Patterns of indoor admissions of leprosy patients in pre-MDT and post-MDT era and a role for leprosy referral hospital in leprosy integrated programme. Indian J Lepr 1997 69 : 159 167.
16. Rogers L, Muir E. Leprosy, 3rd edn. John Wright & Sons, London, 1946 : 213.
17. Bennett NM. Diagnosis of leprosy in Victoria - a non-endemic area of Australia. Med J Aust 1997 2 : 349 351.
18. Boggild AK, Correia JD, Keystone JS, Kain KC. Leprosy in Toronto: an analysis of 184 imported cases. CMAJ 2004 170 : 55 59.
19. Hartzell JD, Zapor M, Peng S, Straight T. Leprosy: a case series and review. South Med J 2004 97 : 1252 1256.
20. Hoffner RJ, Esekogwu V, Mallon WK. Leprosy in the emergency department. Acad Emerg Med 2000 7 : 372 376.
21. International Leprosy Association. The diagnosis and classification of leprosy. Report of the ILA, France, 2002. Int J Lepr 2002 70 (Suppl S23 S31.
22. Lockwood DN, Suneetha S. Leprosy: too complex a disease for a simple elimination paradigm. Bull World Health Organ 2005 83 : 230 235.
23. Azulay RD. Autoaggressive hanseniasis. J Am Acad Dermatol 1987 17 : 1042 1046.
24. Kumar B, Rai R, Kaur I. Systemic involvement in leprosy and its significance. Indian J Lepr 2000 72 : 123 136.
25. Talhari S, Neves RG, Penna GO, Oliveira MLW. Hanseníase, 4th edn. Manaus, 2006.
26. Diogenes MJN, Moralis RM, Tomé GS, Cunha MB, Neto CB. The Lucio-Alvarado-Latapi form of leprosy: A case report. Lepr Rev 2001 72 : 360 362.
27. Ramos-e-Silva M, Oliveira MLW, Munhoz-da-Fontoura GH. Leprosy: uncommon presentations. Clin Dermatol 2005 23 : 509 514.
28. Albert DA, Weisman MH, Kaplan R. The rheumatic manifestations of leprosy (Hansen disease) Medicine (Baltimore) 1980 59 : 442 448.
29. Sadeghi P, Dupree M, Carlson JA. Delay in diagnosis: indeterminate leprosy presenting with rheumatic manifestations. J Cutan Med Surg 2000 4 : 26 29.
30. Overbosch D, Naafs B. Importziekten. In Reitsma WD, Elte JFW, Overbosch D, eds. Differentiële Diagnostiek in de Interne Geneeskunde, 4th edn. Bohn, Stafleu,Van Loghem Houten, The Netherlands, 2005 : 356 381.
31. Rea TH, Levan NE. Erythema nodosum leprosum in a general hospital. Arch Dermatol 1975 111 : 1575 1580.
32. Opromolla DVA. Noções de Hansenologia, Parte 1. Hospital Lauro de Souza Lima, Bauru, Brazil, 1981 : 89 100.
33. Miranda MA, Valentin V, Nery JAC, Sarno EN. Parâmetros clínicos e morfológicos do eritema multiforme na hanseníase. Rev Soc Bras Med Trop 2000 33 (Suppl I 101 102.
34. Barreto JA, Freitas IC. Reação tipo 2 (Eritema Polimorfo Hansênico) como primeira manifestação clínica de hanseníase na faixa virchoviana. Hansen Int 2005 30 : 25 27.
35. Leger M. A lepra incipiente e seus pequenos symptomas. Annaes Bras Dermatologia e Syphilographia 1928 IV : 16 22.
36. Lobato F. Bacillemia no estado apyretico da lepra. Annaes Bras Dermatologia e Syphilographia 1929 V : 21 25.
37. Nery JAC. Estados reacionais na hanseníase: aspectos clínico, fatores de risco e intervenção terapêutica. Doutoramento em Doenças Infeito-Parasitaras. Universidade Federal do Rio de Janeiro, Faculdade de Medicina. Rio de Janeiro 2000 11.
38. Rabelo Filho. 'Perniose na Lepra'. Annaes Bras Dermatologia e Syphilographia 1934 IX : 49 53.
39. Sales AM, Sá RP, Jardim MM et al. Importãncia do reconhecimento clínico da hanseníase. Infectologia 2004 87 : 41 50.
40. Souza CS, Roselino AMF, Fiqueiredo F, Foss NT. Lucio's phenomenon: clinical and therapeutic aspects. Int J Lepr 2000 68 : 417 425.
41. Valentini A, Nery JAC, Salles AM et al. Edema na hanseníase: aspectos clínico e terapêuticos. Rev Soc Bras Med Trop 1999 32 : 131 138.
42. Bagla N, Patel MM, Patel RD, Jarag M. Lepromatous lymphadenitis masquerading as lymphoma. Lepr Rev 2005 76 : 87 90.
43. Leiker DL. Differential diagnosis. In Hastings RC, ed. Leprosy. Medicine in the Tropics Series. Churchill Livingstone, Edinburgh London Melbourne and New York, 1985 : 188 189.
44. Nery JAC, Santos OLR, Spuza MCF et al. Envolvimento ganglionar na hanseníase Virchowiana: a propósito de uma caso de reação hansênica simulando linfogranuloma venéreo. Na Bras Dermato 1996 71 : 205 208.
45. Barman KD, Gupta U, Saify K, Luthra S. Sub-polar lepromatous leprosy presenting as urticarial wheals: a case report. Indian J Lepr 2004 76 : 223 228.