Adverse drug reactions related to hospital admission in Slovak elderly patients

Archives of Gerontology and Geriatrics

Volumn 48, Issue 2, 2009, Pages 186-190

  Wawruch, Martin ^a   Zikavska, Martina ^a   Wsolova, Ladislava ^b   Kuzelova, Magdalena ^c   Kahayova, Katarina ^a   Strateny, Kamil ^a   Kristova, Viera ^a  

^a Faculty of Medicine of Comenius University and University Hospital Bratislava   (Slovakia)

^b SLOVAK MEDICAL UNIVERSITY   (Slovakia)

^c Physics and Informatics   (Slovakia)

Author keywords

Adverse drug reactions; Comorbidity in elderly; Polymorbidity in elderly; Polypharmacy in elderly; Risk factors

Indexed keywords

AMIODARONE; ANTIBIOTIC AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CORTICOSTEROID; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; SPIRONOLACTONE; WARFARIN;

AGED; ARTICLE; BLEEDING; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; COUGHING; DEPRESSION; ELDERLY CARE; EXTRAPYRAMIDAL SYNDROME; GASTROINTESTINAL SYMPTOM; HEART ARRHYTHMIA; HEART FAILURE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HYPERGLYCEMIA; HYPERKALEMIA; HYPERSENSITIVITY; HYPOTENSION; ISCHEMIC HEART DISEASE; LIVER TOXICITY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK FACTOR;

EID: 58349121704     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2008.01.004     Document Type: Article

References (35)

1. Annual Health Report of the Slovak Republic, 2004. Available at: http://www.uzis.sk/publikacie/pdf/rocen-04pdf.
2. Beijer H.J., and De Blaey C.J. Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies. Pharm. World Sci. 24 (2002) 46-54
3. Borda I., Jick H., Slone D., Dinan B., Gilman B., and Chalmers T.C. Studies of drug usage in five Boston hospitals. J. Am. Med. Assoc. 202 (1967) 506-510
4. Bressler R., and Bahl J.J. Principles of drug therapy for the elderly patient. Mayo Clin. Proc. 78 (2003) 1564-1577
5. Caamano F., Pedone C., Zuccala G., and Carbonin P. Socio-demographic factors related to the prevalence of adverse drug reaction at hospital admission in an elderly population. Arch. Gerontol. Geriatr. 40 (2005) 45-52
6. Carbonin P., Pahor M., Bernabei R., and Sgadari A. Is age an independent risk factor of adverse drug reactions in hospitalized medical patients?. J. Am. Geriatr. Soc. 39 (1991) 1093-1099
7. Chatap G., Giraud K., and Vincent J.P. Atrial fibrillation in the elderly: facts and management. Drugs Aging 19 (2002) 819-846
8. Classen D.C., Pestotnik S.L., Evans R.S., and Burke J.P. Computerized surveillance of adverse drug events in hospital patients. J. Am. Med. Assoc. 266 (1991) 2847-2851
9. Classen D.C., Pestotnik S.L., Evans R.S., Lloyd J.F., and Burke J.P. Adverse drug events in hospitalized patients: excess length of stay, extra costs, and attributable mortality. J. Am. Med. Assoc. 277 (1997) 301-306
10. Col N., Fanale J.E., and Kronholm P. The role of medication non-compliance and adverse drug reactions in hospitalizations of the elderly. Arch. Intern. Med. 150 (1990) 841-845
11. Field T.S., Gurwitz J.H., Harrold L.R., Rothschild J., DeBellis K.R., Seger A.C., Auger J.C., Garber L.A., Cadoret C., Fish L.S., Garber L.D., Kelleher M., and Bates D.W. Risk factors for adverse drug events among older adults in the ambulatory setting. J. Am. Geriatr. Soc. 52 (2004) 1349-1354
12. Go A., Hylek E.M., Borowsky L.H., Phillips K.A., Selby J.V., and Singer D.E. Warfarin use among ambulatory patients with non-valvular atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. Ann. Intern. Med. 131 (1999) 927-934
13. Gurwitz J.H., and Avorn J. The ambiguous relation between aging and adverse drug reactions. Ann. Intern. Med. 114 (1991) 956-966
14. Gurwitz J.H., Field T.S., Avorn J., McCormick D., Jain S., Eckler M., Benser M., Edmondson A.C., and Bates D.W. Incidence and preventability of adverse drug events in nursing homes. Am. J. Med. 109 (2000) 87-94
15. Hegyi L., and Krajcik S. The priorities of pharmacotherapy in older age. Geriatria 8 (2002) 101-113
16. ICD. 10th International Statistical Classification of Diseases and Related Health Problems. 10th ed. (1992), WHO, Geneva
17. Lazarou J., Pomeranz B.H., and Corey P.N. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. J. Am. Med. Assoc. 279 (1998) 1200-1205
18. Lindley C.M., Tully M.P., Paramsothy V., and Tallis R.C. Inappropriate medication is a major cause of adverse drug reactions in elderly patients. Age Ageing 21 (1992) 294-300
19. Mannesse C.K., Derkx F.H., de Ridder M.A., Man in 't Veld A.J., and van der Cammen T.J. Contribution of adverse drug reactions to hospital admission of older patients. Age Ageing 29 (2000) 35-39
20. Mjorndal T., Boman M.D., Hagg S., Backstrom M., Wiholm B.E., Wahlin A., and Dahlqvist R. Adverse drug reactions as a cause for admissions to a department of internal medicine. Pharmacoepidemiol. Drug Safe. 11 (2002) 65-72
21. Newman S.C. Biostatistical Methods in Epidemiology (2001), Wiley, Chichester
22. Onder G., Pedone C., Landi F., Cesari M., Della Vedova C., Bernabei R., and Gambassi G. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J. Am. Geriatr. Soc. 50 (2002) 1962-1968
23. Palmer B.F. Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system. N. Engl. J. Med. 351 (2004) 585-592
24. Pouyanne P., Haramburu F., Imbs J.L., and Begaud B. Admissions to hospital caused by adverse drug reactions: cross sectional incidence study. Br. Med. J. 320 (2000) 1036
25. Rajska-Neumann A., and Wieczorowska-Tobis K. Polypharmacy and potential inappropriateness of pharmaco-logical treatment among community-dwelling elderly patients. Arch. Gerontol. Geriatr. 44 (2007) 303-309
26. Rajska-Neumann A., Wieczorowska-Tobis K., Schulz M., Breborowicz A., Grzeskowiak E., and Oreopoulos D.G. Duplicate use of angiotensin-converting enzyme (ACE) inhibitors in a community-dwelling elderly population in Poland. Arch. Gerontol. Geriatr. 44 (2007) 295-301
27. Rawlins M.D., and Thompson J.W. Mechanisms of adverse drug reactions. In: Davies D.M. (Ed). Textbook of Adverse Drug Reactions. 3rd ed. (1985), Oxford University Press, Oxford 12-38
28. Routledge P.A., O'Mahony M.S., and Woodhouse K.W. Adverse drug reactions in elderly patients. Br. J. Clin. Pharmacol. 57 (2003) 121-126
29. Swedberg K., Cleland J., Dargie H., Drexler H., Follath F., Komajda M., Tavazzi L., Smiseth O.A., Gavazzi A., Haverich A., Hoes A., Jaarsma T., Korewicki J., Levy S., Linde C., Lopez-Sendon J.L., Nieminen M.S., Pierard L., and Remme W.J. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005). Eur. Heart J. 26 (2005) 1115-1140
30. Van der Hooft C.S., Sturkenboom M.C.J., van Grootheest K., Kingma H.J., and Stricker B.H.C. Adverse drug reaction-related hospitalisations: a nationwide study in the Netherlands. Drug Safe. 29 (2006) 161-168
31. Veehof L.J.G., Stewart R.E., Meyboom-de Jong B., and Haaijer-Ruskamp F.M. Adverse drug reactions and polypharmacy in the elderly in general practice. Eur. J. Clin. Pharmacol. 55 (1999) 533-536
32. Veehof L.J.G., Stewart R.E., Haaijer-Ruskamp F.M., and Meyboom-de Jong B. The development of polypharmacy. A longitudinal study. Fam. Pract. 17 (2000) 261-267
33. Wawruch M., Zikavska M., Wsolova L., Jezova D., Fialova D., Kunzo M., Kuzelova M., Lassanova M., Kruty P., and Kriska M. Perception of potentially inappropriate medication in elderly patients by Slovak physicians. Pharmacoepidemiol. Drug Safe. 15 (2006) 829-834
34. Westerbotn M., Aguero-Torres H., Fastbom J., and Hilleras P. A population-based study on well-being in the very old: the role of cardiovascular diseases and drugs. Arch. Gerontol. Geriatr. 40 (2005) 287-297
35. Williamson J., and Chopin J.M. Adverse reactions to prescribed drugs in the elderly: a multicentre investigation. Age Ageing 9 (1980) 73-80