Hypertonicity stimulates PGE2 signaling in the renal medulla by promoting EP3 and EP4 receptor expression

Kidney International

Volumn 75, Issue 3, 2009, Pages 278-284

  Kim, Jeong Ah ^a   Sheen, Mee Rie ^a   Lee, Sang Do ^a   Jung, Ju Young ^a   Kwon, H Moo ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Division of Nephrology   (United States)

Author keywords

AQP2; cAMP; Cell survival; Cyclooxygenase 2; NKCC2; Renal blood flow

Indexed keywords

ALDEHYDE REDUCTASE; CARRIER PROTEIN; CYCLIC AMP; CYCLOOXYGENASE 2; FUROSEMIDE; G PROTEIN COUPLED RECEPTOR; HYPERTONIC SOLUTION; MESSENGER RNA; PROSTAGLANDIN E2; PROTEIN EP3 RECEPTOR; PROTEIN EP4 RECEPTOR; PROTEIN SLC5A3; SODIUM CHLORIDE; SORBITOL; UNCLASSIFIED DRUG; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2 RECEPTOR, EP4 SUBTYPE; PROSTAGLANDIN EP3 RECEPTOR;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; HEMODYNAMICS; HUMAN; HUMAN CELL; HYPEROSMOTIC STRESS; KIDNEY MEDULLA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL LINE; CYTOLOGY; DOG; DRUG EFFECT; GENETICS; KIDNEY; MALE; METABOLISM; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; DINOPROSTONE; DOGS; HUMANS; HYPERTONIC SOLUTIONS; KIDNEY; KIDNEY MEDULLA; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER; SALINE SOLUTION, HYPERTONIC; SIGNAL TRANSDUCTION; SORBITOL;

EID: 58349120388     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.498     Document Type: Article

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