The oestrogen receptor-negative/progesterone receptor-positive breast tumor: A biological entity or a technical artefact?

Journal of Clinical Pathology

Volumn 62, Issue 1, 2009, Pages 95-96

  Rhodes, A ^a   Jasani, B ^b  

^a UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ADULT; BREAST TUMOR; CANCER INVASION; CANCER PATIENT; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LETTER; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; TUMOR VOLUME;

EID: 58349118708     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2008.060723     Document Type: Letter

References (7)

1. Rakha EA, El-Sayed ME, Green AR, et al. Biological and clinical characteristics of breast cancer with single hormone receptor-positive phenotype. J Clin Oncol 2007;25:4772-8.
2. Nadji M, Gomez-Ferenandez C, Ganjei-Azar P, et al. Immmunohistochemistry of estrogen and progesterone receptors reconsidered: experience with 5,993 breast cancers. Am J Clin Pathol 2005;123:21-7.
3. Nadji M. Quantitative immunohistochemistry of estrogen receptor in breast cancer. Appl Immunohistochem Mol Morphol 2008;16:105-7.
4. De Maeyer L, Van Limbergen E, De Nys K, et al. Does estrogen receptor-negative/progesterone receptorpositive breast carcinoma exist? J Clin Oncol 2008;26:335-40.
5. Rhodes A, Jasani B, Balaton AJ, et al. Frequency of oestrogen and progesterone receptor positivity by immunohistochemical analysis in 7,016 breast carcinomas: correlation with patient age, assay sensitivity, threshold value and mammographic screening. J Clin Pathol 2000;53:688-96.
6. Harvey JM, Clark GM, Osbourne CK, et al. Estrogen receptor status by immunohistochemistry is superior to the ligand binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999;17:1474-81.
7. Dabbs DJ, Carter GJ, Bhargava R. Fixation issues with breast carcinoma hormone receptors: ER negative PR positive carcinomas exist even with optimal fixation methods. 97th Annual USCAP Meeting 1-7 March 2008:27A.