In situ detection of inflammatory cytokines and apoptosis in pemphigus foliaceus patients

Archives of Pathology and Laboratory Medicine

Volumn 133, Issue 1, 2009, Pages 97-100

  Rodrigues, Denise Bertulucci Rocha ^a,b   Pereira, Sanivia Aparecida Lima ^a,b   Reis, Marlene Antônia Dos ^a   Adad, Sheila Jorge ^a   Caixeta, João Eduardo ^a   Chiba, Angélica Maeda ^a   Sousa, Richard Átila ^a   Rodrigues Jr , Virmondes ^a  

^a FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

^b UNIVERSITY OF UBERABA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; EXUDATE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; NICK END LABELING; PEMPHIGUS FOLIACEUS; PROTEIN EXPRESSION; SKIN BIOPSY;

ANTIGENS, CD95; APOPTOSIS; BIOLOGICAL MARKERS; CELL NUCLEUS; CYTOKINES; ENDEMIC DISEASES; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTERFERON-GAMMA; INTERLEUKIN-1; NITRIC OXIDE SYNTHASE TYPE II; PEMPHIGUS; PROTO-ONCOGENE PROTEINS C-BCL-2; SKIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58349114292     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Stanley JR, Koulu L, Thivolet C. Distinction between epidermal antigens binding pemphigus vulgaris and pemphigus foliaceous autoantibodies. J Clin Invest. 1984;74:313-320.
2. Allen EM, Giudice GJ, Diaz LA. Subclass reactivity of pemphigus foliaceus autoantibodies with recombinant human desmoglein. J Invest Dermatol. 1 993; 100:685-691.
3. Lanza A, Cirillo N. Caspase-dependent cleavage of desmoglein 1 depends on the apoptotic stimulus. Br J Dermatol. 2007;156:400-402.
4. Rocha-Rodrigues DB, Paschoini G, Pereira SAL, dos Reis MA, Teixeira V, Rodrigues V Jr. High levels of interleukin-1 in patients with endemic pemphigus foliaceus. Clin Diagn Lab Immunol. 2003;10:741-743.
5. D'Auria L, Bonifati C, Mussi A, et al. Cytokines in the sera of patients with pemphigus vulgaris: interleukin-6 and tumour necrosis factor-alpha levels are significantly increased as compared to healthy subjects and correlate with disease activity. Eur Cytokine Netw. 1997;8:383-387.
6. Gniadecki R, Jemec GB, Thomsen BM, Hansen M. Relationship between keratinocyte adhesion and death: anoikis in acantolytic diseases. Arch Dermatol Res. 1998;10:528-532.
7. Nagata S, Golstein P. The Fas death factor. Science. 1995;267:1449-1456.
8. Laucella SA, Rottenberg ME, Titto EH. Role of cytokines in resistance and pathology in Trypanosoma cruzi infection. Rev Arg Microbiol. 1996;28:99-109.
9. Shukla A, Rasik AM, Shankar R. Nitric oxide inhibits wounds collagen synthesis. Mol Cell Biochem. 1999;200:27-33.
10. Dhein J, Walczak H, Baumler C, Debatin KM, Krammer PH. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature. 1995;373:438-441.
11. Brunner T, Mogil RJ, Laface D, et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature. 1995;373:441-444.
12. Baroni A, Buommino E, Paoletti I, Orlando M, Ruocco E, Ruocco V. Pemphigus serum and captopril induce heat shock protein 70 and inducible nitric oxide syntase overexpression, triggering apoptosis in human keratinocytes. Br J Dermatol. 2004;150:1070-1080.
13. Puviani M, Marconi A, Cozzani E, Pincelli C. Fas ligant in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8. J Invest Dermatol. 2003;120:164-167.
14. Sayama K, Yonehara S, Watanabe Y, Miki Y. Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes. J Invest Dermatol. 1994;103:330-334.
15. Zuccolotto I, Roselino AM, Ramalho LN, Zucoloto S. Apoptosis and p63 expression in the pathogenesis of bullous lesions of endemic pemphigus foli-aceus. Arch Dermatol Res. 2003;295:284-286.