Structure determination and total synthesis of bottromycin A2: A potent antibiotic against MRSA and VRE

Angewandte Chemie - International Edition

Volumn 48, Issue 5, 2009, Pages 914-917

  Shimamura, Hiroyuki ^a   Gouda, Hiroaki ^a   Nagai, Kenichiro ^a   Hirose, Tomoyasu ^a   Ichioka, Maki ^a   Furuya, Yujiro ^a   Kobayashi, Yutaka ^a   Hirono, Shuichi ^a   Sunazuka, Toshiaki ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Antibiotics; Drug resistance; Natural products; Structure elucidation; Total synthesis

Indexed keywords

AMINES; ANTIBIOTICS; CHEMICAL REACTIONS; DRUG PRODUCTS; MERCURY (METAL); NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CHEMICAL EQUATIONS; CONFORMATION ANALYSES; DRUG RESISTANCE; NATURAL PRODUCTS; STRUCTURE DETERMINATIONS; STRUCTURE ELUCIDATION; SYNTHESIS OF; THIOAMIDE; TOTAL SYNTHESIS;

SYNTHESIS (CHEMICAL);

ANTIINFECTIVE AGENT; BOTTROMYCIN A(2); CYCLOPEPTIDE;

ANTIBIOTIC RESISTANCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; ENTEROCOCCUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGICAL EXAMINATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PENICILLIN RESISTANCE; STEREOISOMERISM; SYNTHESIS;

ANTI-BACTERIAL AGENTS; ENTEROCOCCUS; MAGNETIC RESONANCE SPECTROSCOPY; METHICILLIN RESISTANCE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES, CYCLIC; STEREOISOMERISM; VANCOMYCIN RESISTANCE;

EID: 58349107045     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200804138     Document Type: Article

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