One-dimensional cellulose acetate plate electrophoresis-A feasible method for analysis of dermatan sulfate and other glycosaminoglycan impurities in pharmaceutical heparin

Journal of Pharmaceutical and Biomedical Analysis

Volumn 49, Issue 1, 2009, Pages 151-155

  Domanig, Rainer ^a   Jöbstl, Wolfgang ^a   Gruber, Silvia ^a   Freudemann, Thomas ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Cellulose acetate plate electrophoresis; Chondroitin sulfate; Dermatan sulfate; Glycosaminoglycans; Heparin

Indexed keywords

ALCIAN BLUE; CELLULOSE ACETATE; CHONDROITIN SULFATE; DERMATAN SULFATE; GLYCOSAMINOGLYCAN; HEPARIN; NITROUS ACID;

ANALYTIC METHOD; ARTICLE; CELLULOSE ACETATE PLATE ELECTROPHORESIS; DRUG DEGRADATION; DRUG DETERMINATION; DRUG IMPURITY; DRUG ISOLATION; ELECTROPHORESIS; FEASIBILITY STUDY; GOOD LABORATORY PRACTICE; PRIORITY JOURNAL; STAINING; VALIDATION STUDY;

ALCIAN BLUE; ANTICOAGULANTS; COLORING AGENTS; DERMATAN SULFATE; DRUG CONTAMINATION; ELECTROPHORESIS, CELLULOSE ACETATE; FEASIBILITY STUDIES; GLYCOSAMINOGLYCANS; HEPARIN; QUALITY CONTROL; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; STAINING AND LABELING;

EID: 58349096087     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.10.017     Document Type: Article

References (15)

1. The European Council, European Directorate for the Quality of Medicines & HealthCare. The European Pharmacopoeia. 6th ed. (2008), Strasbourg, France
2. The Unites States Pharmacopeial Convention, The Unites States Pharmacopeia, USP, 30-NF, 25, Rockville, MD, 2008.
3. Linhardt R.J., and Gunay N.S. Semin. Thromb. Hemost 25 (1999) 5-16
4. Holme K.R., and Perlin A.S. Carbohydr. Res. 186 (1989) 301-312
5. Linhardt R.J. Chem. Indust. 2 (1991) 45-50
6. Hirsh J., and Raschke R. Chest 126 Suppl. 3 (2004) 188-203
7. US Food and Drug Administration, Communication. Information on Heparin Sodium Injection, .
8. Guerrini M., Beccati D., Shriver Z., et al. Nat. Biotechnol. 26 (2008) 669-675
9. Kishimoto T.K., Viswanathan K., Ganguly T., et al. N. Engl. J. Med. 358 (2008) 2457-2467
10. Patel R.P., Narkowica C., Hutchinson J.P., Hilder E.F., and Jacobson G.A. J. Pharm. Biomed. Anal. 46 (2008) 30-35
11. Volpi N., and Maccari F. J. Chromatogr. B 834 (2006) 1-13
12. Cappelletti R., Rosso M.D., and Chiarugi V.P. Anal. Biochem. 93 (1979) 37-40
13. Cappelletti R., Rosso M.D., and Chiarugi V.P. Anal. Biochem. 99 (1979) 311-315
14. Cappelletti R., Rosso M.D., and Chiarugi V.P. Anal. Biochem. 105 (1980) 430-435
15. Hopwood J.J., and Harrison J.R. Anal. Biochem. 119 (1981) 120-127