Common mutations in the LRRK2 exon 41 are not responsible for essential tremor in Italian patients

Parkinsonism and Related Disorders

Volumn 15, Issue 2, 2009, Pages 162-163

  Vitale, C ^a,b   Ciotti, P ^c   Gulli, R ^c   Bellone, E ^c   Scaglione, C ^d   Abbruzzese, G ^c   Martinelli, P ^d   Barone, P ^a   Mandich, P ^c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Istituto di Diagnosi e Cura Hermitage Capodimonte   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE RICH REPEAT KINASE 2;

DNA EXTRACTION; ESSENTIAL TREMOR; EXON; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC SUSCEPTIBILITY; HUMAN; LETTER; LINKAGE ANALYSIS; PARKINSON DISEASE; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; DNA REPEAT EXPANSION; ESSENTIAL TREMOR; EXONS; FEMALE; HUMANS; ITALY; LEUCINE; MALE; MIDDLE AGED; PROTEIN-SERINE-THREONINE KINASES;

EID: 58349085979     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2008.04.035     Document Type: Letter

References (5)

1. Aridon P., Ragonese P., De Fusco M., Salemi G., Casari G., and Savettieri G. Further evidence of genetic heterogeneity in familial essential tremor. Parkinsonism Relat Disord 14 (2008) 15-18
2. Shahed J., and Jankovic J. Exploring the relationship between essential tremor and Parkinson's disease. Parkinsonism Relat Disord 13 2 (2007) 67-76
3. Paisán-Ruíz C., Nath P., Washecka N., Gibbs J.R., and Singleton A.B. Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls. Hum Mutat 29 4 (2008) 485-490
4. Skipper L., Shen H., Chua E., Bonnard C., Kolatkar P., Tan L.C., et al. Analysis of LRRK2 functional domain in non dominant Parkinson's disease. Neurology 65 8 (2005) 1319-1321
5. Deng H., Le W.D., Davidson A.L., Xie W.J., and Jankovic J. The LRRK2 I2012T, G2019S and I2020T mutations are not common in patients with essential tremor. Neurosci Lett 407 2 (2006) 97-100