Validation of preimplantation genetic diagnosis by PCR analysis: Genotype comparison of the blastomere and corresponding embryo, implications for clinical practice

Molecular Human Reproduction

Volumn 14, Issue 10, 2008, Pages 573-579

  Dreesen, Jos ^a,c   Drusedau M ^a   Smeets, H ^a,c   de Die Smulders, C ^a,c   Coonen, E ^a   Dumoulin, J ^a   Gielen, M ^b,c,d   Evers, J ^a,c   Herbergs, J ^a,c   Geraedts, J ^a,c  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Embryo morphology; Negative predictive value; Preimplantation diagnosis; Preimplantation genetic diagnosis; Sensitivity

Indexed keywords

ARTICLE; BLASTOMERE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; DIAGNOSTIC VALUE; EMBRYO; FALSE NEGATIVE RESULT; GENOTYPE; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PREDICTIVE VALIDITY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; VALIDITY;

BLASTOMERES; FEMALE; GENOTYPE; HUMANS; POLYMERASE CHAIN REACTION; PREGNANCY; PREIMPLANTATION DIAGNOSIS; REPRODUCIBILITY OF RESULTS;

EID: 58249112936     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gan052     Document Type: Article

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