Pain management in chronic kidney disease: The pharmacokinetics and pharmacodynamics of hydromorphone and hydromorphone-3-glucuronide in hemodialysis patients

Journal of Opioid Management

Volumn 4, Issue 6, 2008, Pages 335-344

  Davison, Sara N ^a   Mayo, Patrick R ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b Isotechnika Inc   (Canada)

Author keywords

Chronic pain; Dialysis; Hydromorphone; Hydromorphone 3 glucuronide; Kidney failure; Opioids; Pharmacodynamics; Pharmacokinetics

Indexed keywords

DRUG METABOLITE; HYDROMORPHONE; HYDROMORPHONE 3 GLUCURONIDE; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; AREA UNDER THE CURVE; ARTICLE; CANADA; CHRONIC KIDNEY DISEASE; CHRONIC PAIN; CLINICAL ARTICLE; CONSTIPATION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; FEMALE; GASTROESOPHAGEAL REFLUX; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MCGILL PAIN QUESTIONNAIRE; NAUSEA; OBSERVATIONAL STUDY; PAIN ASSESSMENT; PATIENT SELECTION; PRURITUS; RESPIRATION DEPRESSION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCORING SYSTEM; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT DURATION; VISUAL ANALOG SCALE; XEROSTOMIA;

EID: 58249102996     PISSN: 15517489     EISSN: None     Source Type: Journal    
DOI: 10.5055/jom.2008.0037     Document Type: Article

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