Isn't the efficacy of antidepressants clinically relevant? A critical comment on the results of the metaanalysis by Kirsch et al. 2008

European Archives of Psychiatry and Clinical Neuroscience

Volumn 258, Issue 8, 2008, Pages 451-455

  Möller, Hans Jürgen ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antidepressants; Effectiveness; Meta analyses

Indexed keywords

ANTIDEPRESSANT AGENT;

DEPRESSION; DRUG EFFICACY; DRUG RESEARCH; HUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; REVIEW;

ANTIDEPRESSIVE AGENTS; HUMANS; META-ANALYSIS AS TOPIC; REVIEW LITERATURE AS TOPIC; TREATMENT OUTCOME;

EID: 58249096046     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-008-0836-5     Document Type: Review

References (20)

1. IM Anderson 2000 Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability J Affect Disord 58 19 36
2. TC Baghai HP Volz HJ Moller 2006 Drug treatment of depression in the 2000s: an overview of achievements in the last 10 years and future possibilities World J Biol Psychiatry 7 198 222
3. D Baldwin K Broich J Fritze S Kasper H Westenberg HJ Möller 2003 Placebo-controlled studies in depression: necessary, ethical and feasible Eur Arch Psychiatry Clin Neurosci 253 22 28
4. M Bauer T Bschor A Pfennig PC Whybrow J Angst M Versiani HJ Moller 2007 World federation of societies of biological psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders in primary care World J Biol Psychiatry 8 67 104
5. J Fritze J Aldenhoff F Bergmann W Maier HJ Möller 2005 Antidepressiva: Lebensgefährliche Placebos? Arznei-Telegramm: fahrlässiges journal? Psychoneuro 31 480 484
6. J Fritze HJ Möller 2001 Design of clinical trials of antidepressants. Should a placebo control arm be included? CNS Drugs 15 10 755 764
7. JR Geddes SM Carney C Davies TA Furukawa DJ Kupfer E Frank GM Goodwin 2003 Relapse prevention with antidepressant drug treatment in depressive disorders: a systematic review Lancet 361 653 661
8. Kirsch I, Moore TJ, Scoboria A, Nicholls S (2002) The emperor's new drugs: an analyses of antidepressant medication data submitted to the U.S. Food and Drug Administration. Prevention & Treatment 5 (Artikle 23)
9. I Kirsch BJ Deacon TB Huedo-Medina A Scoboria TJ Moore BT Johnson 2008 Initial severity and antidepressant benefits: a meta-analysis of data submitted to the food and drug administration PLoS Med 5 260 268
10. W Maier HJ Möller 2007 Metaanalysen. Methoden zur Evidenzmaximierung von Therapiestudien Nervenarzt 78 1028 1036
11. HJ Möller 2008 Is there a need for a new psychiatric classification at the current state of knowledge? World J Biol Psychiatry 9 82 85
12. Möller HJ (2008b) Methodik empirischer Forschung. In: Möller HJ, Laux G, Kapfhammer H-P (eds) Psychiatrie und psychotherapie. Springer, Heidelberg, pp 346-367
13. HJ Möller W Maier 2007 Probleme der "evidence-based medicine" in der Psychopharmakotherapie. Problematik der Evidenzgraduierung und der Evidenzbasierung komplexer klinischer Entscheidungsprozesse Nervenarzt 78 1014 1027
14. SA Montgomery S Kasper 2007 Severe depression and antidepressants: focus on a pooled analysis of placebo-controlled studies on agomelatine Int Clin Psychopharmacol 22 283 291
15. Montgomery SA, Möller HJ (2008) The clinical relevance of the significant advantage of escitaloprom compared to other antidepressants. (in preperation)
16. National Institute for Clinical Excellence (2004) Depression: management of depression in primary and secondary care. Clinical practice guideline no 23. National Institute for Clinical Excellence, London
17. DJ Nutt M Sharpe 2008 Uncritical positive regard? Issues in the efficacy and safety of psychotherapy J Psychopharmacol 22 3 6
18. AJ Russh 2007 STAR D: what have we learned? Am J Psychiatry 164 201 204
19. Storosum JG, Elferink AJ, van Zwieten BJ, van den BW, Gersons BP, van Strik R, Broekmans AW (2001) Short-term efficacy of tricyclic antidepressants revisited: a meta-analytic study. Eur Neuropsychopharmacol 11:173-180
20. EH Turner AM Matthews E Linardatos RA Tell R Rosenthal 2008 Selective publication of antidepressant trials and its influence on apparent efficacy N Engl J Med 358 252 260