Prospective study evaluating olfactometric and rhinomanometric outcomes in postmenopausal women on 1 mg 17β-estradiol and 2 mg drospirenone HT

Menopause

Volumn 15, Issue 5, 2008, Pages 967-972

  Caruso, Salvatore ^a,c   Serra, Agostino ^a   Grillo, Calogero ^a   De Leo, Vincenzo ^b   Maiolino, Luigi ^a   Agnello, Carmela ^a   Cianci, Antonio ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c Ospedale S Bambino   (Italy)

Author keywords

Drospirenone; Hormone therapy; Menopause; Olfactometric threshold; Rhinomanometry

Indexed keywords

DROSPIRENONE; ESTRADIOL; ANDROSTANE DERIVATIVE; PROGESTERONE DERIVATIVE;

ADULT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HORMONAL THERAPY; HUMAN; MAJOR CLINICAL STUDY; NOSE AIRWAY RESISTANCE; OLFACTOMETRY; OLFACTORY SYSTEM; POSTMENOPAUSE; PROSPECTIVE STUDY; RHINOMANOMETRY; SENSITIVITY ANALYSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; ESTROGEN THERAPY; METHODOLOGY; MIDDLE AGED; ODOR; OLFACTORY EPITHELIUM; SMELLING;

ANDROSTENES; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; MIDDLE AGED; OLFACTORY MUCOSA; OLFACTORY PERCEPTION; POSTMENOPAUSE; PROGESTERONE CONGENERS; PROSPECTIVE STUDIES; RHINOMANOMETRY; SMELL;

EID: 58249090132     PISSN: 10723714     EISSN: None     Source Type: Journal    
DOI: 10.1097/gme.0b013e31816be973     Document Type: Article

References (32)

1. Hammond CB. Menopause and hormone replacement therapy: an overview. Obstet Gynecol 1996;87:2s-15s.
2. Burger HG. The endocrinology of the menopause. J Steroid Biochem Mol Biol 1999;69:31-35.
3. Nelson HD, Humphrey LL, Nygren P, Teutsch SM, Allan JD. Postmenopausal hormone replacement therapy. Scientific review. JAMA 2002;288:872-881.
4. Caruso S, Roccasalva L, Sapienza G, Zappalà M, Nuciforo G, Biondi S. Laryngeal cytological aspects in women with surgically induced menopause who were treated with transdermal estrogen replacement therapy. Fertil Steril 2000;74:1073-1079.
5. Doty RL. Influence of age and age-related diseases on olfactory function. Ann N Y Acad Sci 1989;561:76-86.
6. Farbman A. The Biology of Olfaction. Cambridge, UK: Cambridge University Press, 1992.
7. Ship A, Pearson JD, Criuse LJ, Brant LJ, Matter EJ. Longitudinal changes in smell identification. J Gerontol 1996;51:M86-M91.
8. Kern RC, Conley DB, GK Haines 3rd, Robinson AM. Pathology of the olfactory mucosa: implications for the treatment of olfactory dysfunction. Laryngoscope 2004;114:279-285.
9. Temmel AF, Quint C, Schickinger-Fischer B, Klimek L, Stoller E, Hummel T. Characteristics of olfactory disorders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg 2002;28:35-41.
10. Grillo C, La Mantia I, Triolo C, Scollo A, Intelisano G, Caruso S. Rhinomanometric and olfactometric variations throughout the menstrual cycle. Ann Otol Rhinol Laryngol 2001;110:785-789.
11. Caruso S, Grillo C, Agnello C, Maiolino L, Intelisano G, Serra A. A prospective study evidencing rhinomanometric and olfactometric outcomes in women taking oral contraceptives. Hum Reprod 2001;16:2288-2294.
12. Haeggstrom A, Ostberg B, Stjerna P, Graf P, Hallen H. Nasal mucosal swelling and reactivity during a menstrual cycle. ORL J Otorhinolaryngol Relat Spec 2000;62:39-42.
13. Serra A, Maiolino L, Farina M, et al. Cytologic aspects of the nasal respiratory epithelium throughout the menstrual cycle. Ann Otol Rhinol Laryngol 2004;113:667-671.
14. Caruso S, Serra A, Maiolino L, et al. Cytological aspects of the nasal respiratory epithelium in reproductive-age women taking oral contraceptives. Eur J Contracept Reprod Health Care 2006;11:250-257.
15. Caruso S, Roccasalva L, Di Fazio E, et al. Cytological aspects of the nasal respiratory epithelium in postmenopausal women treated with hormone therapy. Fertil Steril 2003;79:543-549.
16. Caruso S, Grillo C, Agnello C, Di Mari L, Farina M, Serra A. Olfactometric and rhinomanometric outcome in postmenopausal women treated with hormone therapy: a prospective study. Hum Reprod 2004;19:2959-2964.
17. Kovacs T. Mechanisms of olfactory dysfunction in aging and neurodegenerative disorders. Aging Res Rev 2004;3:215-232.
18. Foidart JM. Added benefits of drospirenone for compliance. Climacteric 2005;8(Suppl 3):28-34.
19. Sitruk-Ware R. Pharmacology of different progestogens: the special case of drospirenone. Climacteric 2005;8(Suppl 3):4-12.
20. Palacios S, Foidart JM, Genazzani AR. Advances in hormone replacement therapy with drospirenone, a unique progestogen with aldosterone receptor antagonism. Maturitas 2006;55:297-307.
21. Oelkers WH. Drospirenone in combination with estrogens: for contraception and hormone replacement therapy. Climacteric 2005;8(Suppl 3):19-27.
22. Archer DF. Drospirenone and estradiol: a new option for the postmenopausal woman. Climacteric 2007;10(Suppl 1):3-10.
23. White WB. Drospirenone with 17β-estradiol in the postmenopausal woman with hypertension. Climacteric 2007;10(Suppl 1):25-31.
24. World Health Organization. Research on the Menopause in the 1990s. Report of a WHO Scientific Group. WHO Technical Report Series No. 866. Geneva: World Health Organization, 1996.
25. Velle W. Sex differences in sensory functions. Perspect Biol Med 1987;30:491-523.
26. Hughes LF, McAsey ME, Donathan CL, Smith T, Coney P, Struble RG. Effects of hormone replacement therapy on olfactory sensitivity: cross-sectional and longitudinal studies. Climacteric 2002;5:140-150.
27. Fruzzetti F, Lazzarini V, Ricci C, et al. Effect of an oral contraceptive containing 30 Kg ethinylestradiol plus 3 mg drospirenone on body composition of young women affected by premenstrual syndrome with symptoms of water retention. Contraception 2007;76:190-194.
28. Engen T, Kuisma JE, Eimas PD. Short-term memory odors. J Exp Psychol 1973;99:222-225.
29. Baker LM, Weaver CA. Rapid permanent loss of memory for absolute intensity of taste and smell. Bull Psychosom Soc 1983;21:281-284.
30. Engen T, Ross BM. Long-term memory of odors with and without verbal description. J Exp Psychol 1973;100:227-237.
31. Savic I. Processing of odorous signals in humans. Brain Res Bull 2001;14:307-312.
32. Dalton P, Wysocki CJ. The nature and duration of adaptation following long-term odor exposure. Percept Psychophys 1996;58:781-792.