Folic acid supplementation for women with epilepsy who might become pregnant

Nature Clinical Practice Neurology

Volumn 5, Issue 1, 2009, Pages 16-17

  Lagrange, Andre H ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; FOLIC ACID; LAMOTRIGINE; OXCARBAZEPINE; PHENYTOIN; VALPROIC ACID;

BIRTH DEFECT; CLINICAL TRIAL; COGNITIVE DEFECT; COMBINATION CHEMOTHERAPY; CONGENITAL MALFORMATION; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; EPILEPSY; FOLATE METABOLISM; FOLIC ACID BLOOD LEVEL; FOLIC ACID DEFICIENCY; HIGH RISK PREGNANCY; HUMAN; MATERNAL TREATMENT; MONOTHERAPY; NOTE; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PREGNANCY; PRENATAL CARE; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROTECTION; RISK BENEFIT ANALYSIS; RISK REDUCTION; SIDE EFFECT; SPONTANEOUS ABORTION; TERATOGENICITY; UNPLANNED PREGNANCY; VITAMIN SUPPLEMENTATION;

EID: 58249088912     PISSN: 1745834X     EISSN: 17458358     Source Type: Journal    
DOI: 10.1038/ncpneuro0970     Document Type: Note

References (7)

1. Meador KJ et al. (2007) Cognitive/behavioral teratogenetic effects of antiepileptic drugs. Epilepsy Behav 11: 292-302
2. Marson AG et al. (2007) The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: An unblinded randomised controlled trial. Lancet 369 1016-1026
3. Pennell PB (2004) Pregnancy in women who have epilepsy. Neurol Clin 22: 799-820
4. MRC Vitamin Study Research Group (1991) Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study. Lancet 338: 131-137
5. [No authors listed] (1998) Practice parameter: Management issues for women with epilepsy (summary statement): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Epilepsia 39 1226-1231
6. Hernández-Díaz S et al. (2000) Folic acid antagonists during pregnancy and the risk of birth defects. N Engl J Med 343: 1608-1614
7. Pittschieler S et al. (2008) Spontaneous abortion and the prophylactic effect of folic acid supplementation in epileptic women undergoing antiepileptic therapy. J Neurol [doi:10.1007/ s00415-008-0029-1]