Is antibiotic prophylaxis in children with vesicoureteral reflux effective in preventing pyelonephritis and renal scars? A randomized, controlled trial

Pediatrics

Volumn 122, Issue 6, 2008, Pages 1409-1410

  Keren, Ron ^a   Carpenter, Myra ^b   Greenfield, Saul ^c   Hoberman, Alejandro ^d   Mathews, Ranjiv ^e   Mattoo, Tej ^f   Chesney, Russell ^g  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c CHILDREN S HOSPITAL OF BUFFALO   (United States)

^d CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Department of Pediatrics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; COTRIMOXAZOLE; ANTIINFECTIVE AGENT; URINARY TRACT ANTIINFECTIVE AGENT;

ANTIBIOTIC PROPHYLAXIS; CHILD; CLINICAL TRIAL; CONTAMINATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; INFANT; KIDNEY SCAR; LETTER; MULTICENTER STUDY; PRIORITY JOURNAL; PYELONEPHRITIS; PYURIA; RANDOMIZED CONTROLLED TRIAL; URINARY TRACT INFECTION; URINE CULTURE; VESICOURETERAL REFLUX; DRUG EFFECT; FEMALE; KIDNEY; MALE; NOTE; PATHOLOGY; PRESCHOOL CHILD; PROGNOSIS; REFERENCE VALUE; RISK ASSESSMENT; SCAR; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; URINALYSIS;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS, URINARY; ANTIBIOTIC PROPHYLAXIS; CHILD; CHILD, PRESCHOOL; CICATRIX; FEMALE; HUMANS; INFANT; KIDNEY; MALE; PROGNOSIS; PYELONEPHRITIS; REFERENCE VALUES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; URINALYSIS; VESICO-URETERAL REFLUX;

EID: 58249087360     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2008-2339     Document Type: Letter

References (4)

1. Pennesi M, Travan L, Peratoner L, et al. Is antibiotic prophylaxis in children with vesicoureteral reflux effective in preventing pyelonephritis and renal scars? A randomized, controlled trial. Pediatrics. 2008;121(6). Available at: www.pediatrics.org/cgi/ content/full/121/6/e1489
2. McGillivray D, Mok E, Mulrooney E, Kramer MS. A head-to-head comparison: "clean-void" bag versus catheter urinalysis in the diagnosis of urinary tract infection in young children. J Pediatr. 2005;147(4):451-456
3. Roussey-Kesler G, Gadjos V, Idres N, et al. Antibiotic prophylaxis for the prevention of recurrent urinary tract infection in children with low grade vesicoureteral reflux: results from a prospective randomized study. J Urol. 2008;179(2):674-679; discussion 679
4. Garin EH, Olavarria F, Garcia Nieto V, Valenciano B, Campos A, Young L. Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study. Pediatrics. 2006; 117(3):626-632