What is the real contribution of extrahepatic cells to liver regeneration?

Surgery Today

Volumn 39, Issue 1, 2009, Pages 1-4

  Eguchi, Susumu ^a   Kanematsu, Takashi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Cell fusion; Extrahepatic stem cells; Liver regeneration; Transdifferentiation

Indexed keywords

BONE MARROW CELL; CELL DIFFERENTIATION; LIVER INJURY; LIVER REGENERATION; REVIEW;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL FUSION; CELL TRANSDIFFERENTIATION; GREEN FLUORESCENT PROTEINS; HEPATECTOMY; HUMANS; LIVER DISEASES; LIVER REGENERATION;

EID: 58149522262     PISSN: 09411291     EISSN: 14362813     Source Type: Journal    
DOI: 10.1007/s00595-008-3836-1     Document Type: Review

References (31)

1. N.D. Theise S. Badve R. Saxena O. Henegariu S. Sell J.M. Crawford 2000 Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation Hepatology 31 235 240
2. U. Baccarani A. Donini A. Risaliti F. Bresadola 2001 Replacement of liver venous endothelium Lancet 357 2137
3. M. Körbling R.L. Katz A. Khanna A.C. Ruifrok G. Rondon M. Albitar 2002 Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells N Eng J Med 346 738 746
4. H. Fujii T. Hirose S. Oe K. Yasuchika H. Azuma T. Fujikawa 2002 Contribution of bone marrow cells to liver regeneration after partial hepatectomy in mice J Hepatol 36 653 659
5. N. Ferry M. Hadchouel 2002 Liver regeneration: with a little help from marrow J Hepatol 36 695 697
6. S. Terai I. Sakaida H. Nishina K. Okita 2005 Lesson from the GFP/CCl4 model-translational research project: the development of cell therapy using autologous bone marrow cells in patients with liver cirrhosis J Hepatobiliary Pancreat Surg 12 203 207
7. I. Sakaida S. Terai N. Yamamoto K. Aoyama T. Ishikawa H. Nishina 2004 Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice Hepatology 78 83 88
8. J.S. am Esch 2nd W.T. Knoefel M. Klein A. Ghodsizad G. Fuerst L.W. Poll 2005 Portal application of autologous CD133+ bone marrow cells to the liver: a novel concept to support hepatic regeneration Stem Cells 23 463 470
9. L.O. Conzelmann I.N. Hines M. Kremer A.W. Perry J.J. Lemasters M.D. Wheeler 2007 Extrahepatic cells contribute to the progenitor/ stem cell response following reduced-size liver transplantation in mice Exp Biol Med (Maywood) 232 571 580
10. M.H. Dahlke F.C. Popp F.H. Bahlmann H. Aselmann M.D. Jäger M. Neipp 2003 Liver regeneration in a retrorsine/CCl4-induced acute liver failure model: do bone marrow-derived cells contribute? J Hepatol 39 365 373
11. D. Hunter Best W.B. Coleman 2008 Cells of origin of small hepatocytelike progenitor cells in the retrorsine model of rat liver injury and regeneration J Hepatol 48 369 371
12. C. Di Campli A.C. Piscaglia F. Giuliante S. Rutella G. Bonanno M.A. Zocco 2005 No evidence of hematopoietic stem cell mobilization in patients submitted to hepatectomy or in patients with acute on chronic liver failure Transplant Proc 37 2563 2566
13. Y. Moritoki Y. Ueno N. Kanno Y. Yamagiwa K. Fukushima M.E. Gershwin 2006 Lack of evidence that bone marrow cells contribute to cholangiocyte repopulation during experimental cholestatic ductal hyperplasia Liver Int 26 457 466
14. K. Tomiyama M. Miyazaki M. Nukui M. Takaishi A. Nakao N. Shimizu 2007 Contribution of cells of intact extrahepatic tissue origin to hepatocyte regeneration in transplanted rat liver Transplantation 83 624 630
15. F.C. Popp P. Slowik E. Eggenhofer P. Renner S.A. Lang O. Stoeltzing 2007 No contribution of multipotent mesenchymal stromal cells to liver regeneration in a rat model of prolonged hepatic injury Stem Cells 25 639 645
16. S. Terai T. Ishikawa K. Omori K. Aoyama Y. Marumoto Y. Urata 2006 Improved liver function in patients with liver cirrhosis after autologous bone marrow cell infusion therapy Stem Cells 24 2292 2298
17. S. Eguchi A. Kamlot J. Ljubimova L.T. Lebow A.A. Demetriou J. Rozga 1996 A novel experimental animal model of fulminant hepatic failure. Survival and effect on biochemistry and liver regeneration Hepatology 1452-1459 24
18. S. Eguchi K. Yanaga N. Sugiyama S. Okudaira J. Furui T. Kanematsu 2003 Changes in serum levels of hepatocyte growth factor in patients undergoing adult-to-adult living donor liver transplantation Transplantation 76 1769 1770
19. M.Y. Gordon N. Levicar M. Pai P. Bachellier I. Dimarakis F. Al-Allaf 2006 Characterization and clinical application of human CD34+ stem/progenitor cell populations mobilized into the blood by granulocyte colony-stimulating factor Stem Cells 24 1822 1830
20. T. Cantz A.D. Sharma A. Jochheim-Richter L. Arseniev C. Klein M.P. Manns 2004 Reevaluation of bone marrow-derived cells as a source for hepatocyte regeneration Cell Transplant 13 659 666
21. P. Beaudry Y. Hida T. Udagawa I.P. Alwayn A.K. Greene D. Arsenault 2007 Endothelial progenitor cells contribute to accelerated liver regeneration J Pediatr Surg 42 1190 1198
22. H.S. Lai Y. Chen W.H. Lin C.N. Chen H.C. Wu C.J. Chang 2005 Quantitative gene expression analysis by cDNA microarray during liver regeneration after partial hepatectomy in rats Surg Today 35 396 403
23. K.D. Lee T.K. Kuo J. Whang-Peng Y.F. Chung C.T. Lin S.H. Chou 2004 In vitro hepatic differentiation of human mesenchymal stem cells Hepatology 40 1275 1284
24. M. Brulport W. Schormann A. Bauer M. Hermes C. Elsner F.J. Hammersen 2007 Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers Hepatology 46 861 870
25. T. Wu K. Cieply M.A. Nalesnik P.S. Randhawa P.S. Randhawa A. Sonzogni 2003 Minimal evidence of transdifferentiation from recipient bone marrow to parenchymal cells in regenerating and long-surviving human allografts Am J Transplant 3 1173 1181
26. F.D. Camargo M. Finegold M.A. Goodell 2004 Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners J Clin Invest 113 1266 1270
27. H. Willenbring A.S. Bailey M. Foster M. Foster Y. Akkari C. Dorrell 2004 Myelomonocytic cells are sufficient for therapeutic cell fusion in liver Nat Med 10 744 748
28. O. Quintana-Bustamante A. Alvarez-Barrientos A.V. Kofman I. Fabregat J.A. Bueren N.D. Theise 2006 Hematopoietic mobilization in mice increases the presence of bone marrow-derived hepatocytes via in vivo cell fusion Hepatology 43 108 116
29. G. Vassilopoulos P.R. Wang D.W. Russell 2003 Transplanted bone marrow regenerates liver by cell fusion Nature 422 901 904
30. X. Wang H. Willenbring Y. Akkari Y. Torimaru M. Foster M. Al-Dhalimy 2003 Cell fusion is the principal source of bone-marrow-derived hepatocytes Nature 422 897 901
31. Y. Kawashita C. Guha K. Yamanouchi Y. Ito Y. Kamohara T. Kanematsu 2005 Liver repopulation: A new concept of hepatocyte transplantation Surg Today 35 705 710