Elective lymph node dissections - Still a standard in cancer surgery?;Sind elektive Lymphknotendissektionen in der Karzinomchirurgie noch zeitgemäß?

Zentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie

Volumn 133, Issue 6, 2008, Pages 582-589

  Holzel D ^a,b,d   Engel, J ^b   Lohrs U ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Pathologischen Instituts und Früherer Vorsitzender des Tumorzentrums München ^*

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cancer surgery; Lymph node dissection; Metastatic spread

Indexed keywords

ARTICLE; CANCER STAGING; COHORT ANALYSIS; ELECTIVE SURGERY; FOLLOW UP; HUMAN; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MORTALITY; NEOPLASM; PATHOLOGY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; REGISTER; STANDARD; SURVIVAL;

COHORT STUDIES; FOLLOW-UP STUDIES; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; NEOPLASM STAGING; NEOPLASMS; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REGISTRIES; SURGICAL PROCEDURES, ELECTIVE; SURVIVAL ANALYSIS;

EID: 58149520237     PISSN: 0044409X     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1098738     Document Type: Article

References (50)

1. Bernards R, Weinberg RA. A progression puzzle. Nature 2002; 418: 823-823
2. Bonenkamp JJ, Hermans J, Sasko M et al. Extended lymph-node dissection for gastric cancer. N Engl J Med 1999; 340: 908 - 914
3. Bruch HP, Schwandner O, Schiedeck THK et al. Actual standards and controversies on operative technique and lymph-node dissection in colorectal cancer. Langenbeck's Arch Surg 1999; 384: 167-175
4. Bui L, Rempel E, Reeson D et al. Lymph node counts, rates of positive lymph nodes, and patient survival for colon cancer surgery in Ontario, Canada: a population-based study. J Surg Oncol 2006; 93: 439-445
5. Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nature Rev Cancer 2002; 2: 563
6. Chen SL, Bilchik AJ. More extensive nodal dissection improves survival for stages I to III of colon cancer - A population-based study. Ann Surg 2006; 244: 602-610
7. Crile C. Excision of cancer of the head and neck. JAMA 1906; 47: 1780
8. DiMarco DS, Zincke H, Sebo TJ et al. The extent of lymphadenectomy for pTXNO prostate cancer does not affect prostate cancer outcome in the prostate specific antigen era. J Urol 2005; 173: 1121 -1125
9. Early Breast Cancer Trialists' Collaborative Group. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 366: 2087-2106
10. Eccles SA, Welch DR. Metastasis: recent discoveries and novel treatment strategies. Lancet 2007; 369: 1742 -1757
11. Engel J, Lebeau A, Sauer H et al. Are we wasting our time with the sentinel technique? Fifteen reasons to stop axilla dissection. The Breast 2006; 15: 452
12. Engel J, Hölzel D. Signal für einen Paradigmawechsel. Dtsch Ärztebl 2001; 98: A2365 (Leserbrief zum .,Konzept des Wächterlymphknotens")
13. Engel J, Eckel R, Kerr J et al. The process of metastasisation for breast cancer. Eur J Cancer 2003; 39: 1794-1806
14. Feinstein AR, Sosin DM, Wells CK. The Will Rogers phenomenon. Stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer. N Engl J Med 1985; 312: 1604-1608
15. Ferlito A, Johnson JT, Rinaldo A et al. European surgeons were the first to perform neck dissection. Laryngoscope 2007; 117: 797 - 802
16. Ferlito A, Rinaldo A. Errare humanum est, in errore perseverare stultum: this is true also for neck dissection. Oral Oncology 2005; 41: 132-134
17. Fidler IJ The pathogenesis of cancer metastasis: the "seed and soil" hypothesis revisited. Nature Rev Cancer 2003; 3: 1
18. Fisher B, Jeong JH, Anderson S et al. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N Engl J Med 2002; 347: 567
19. Fisher B, Anderson S, Bryant J et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002; 347: 1233-1241
20. Gatta G, Capocaccia R, Sant M et al. Understanding variations in survival for colorectal cancer in Europe: a EUROCARE high resolution study. Gut 2000; 47: 533-538
21. Gervasoni JE, Sbayi S, Cady B. Role of lymphadenectomy in surgical treatment of solid tumors: An update on the clinical data. Ann Surg Oncol 2007; 14: 2443-2462
22. Halsted W. The results of operations for the cure of the cancer of the breast performed at the Johns Hopkins Hospital from June 1889 to January 1894. Arch Surg 1894; 20: 497
23. Hanahan D, Weinberg RA. The hallmarks of cancer cell. Cell 2000; 100: 57
24. Hartgrink HH, van de Velde CJH, Putter H et al. Extended lymph node dissection for gastric cancer: Who may benefit? Final results of the randomised Dutch Gastric Cancer Group Trial. J Clin Oncol 2004; 22: 2069-2077
25. Hirakawa S, Brown LF, Kodama S et al. VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites. Blood 2007; 109: 1010-1017
26. Hohenberger W, Merkel S, Weber K. Lymphadenektomie bei Tumoren des unteren Gastrointestinaltraktes. Chirurg 2007; 78: 217-225
27. International Breast Cancer Study Group. Randomized trial comparing axillary clearance versus no axillary clearance in older patients with breast cancer: First results of International Breast Cancer Study Group Trial 10-93. J Clin Oncol 2006; 24: 337-344
28. Kang Y, Siegel PM, Shu W et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003; 3: 537
29. Klein CA, Hölzel D. Systemic cancer progression and tumor dormancy. Cell Cycle 2006; 5: 1788-1798
30. Lähdesmäki H, Hao X, Sun B et al. Distinguishing key biological pathways between primary breast cancers and their lymph node metastases by gene function-based clustering analysis. Int J Oncol 2004; 24: 1589-1596
31. Liu R, Wang X, Chen GY et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med 2007; 356: 217 -226
32. Minn AJ, Gupta GP, Siegel PM et al. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436: 518
33. Morton DL, Thompson JF, Cochran AJ et al. Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med 2006; 355: 1307
34. Neuhaus SJ, Clark MA, Thomas JM. Dr. Herbert Lumley Snow, MRCS (1847-1930): the original champion of elective lymph node dissection in melanoma. Annals Surg Oncol 2004; 11: 875 - 878
35. Pachmann K, Clement JH, Schneider CP et al. Standardized quantification of circulating peripheral tumor cells from lung and breast cancer. Clin Chem Lab Med 2005; 43: 617-627
36. Pack GT, Scharnagel IM, Morfit M. The principle of excision and dissection in continuity for primary and metastatic melanoma of the skin. Surgery 1945; 17: 849
37. Rouffet F, Hay JM, Vacher B et al. Curative resection for left colonic carcinoma: Hemicolectomy vs. segmentel colectomy. Dis Colon Rectum 1994; 37: 651
38. SauerR, BeckerH, Hohenberger W et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351 : 1731
39. Schröder F, Kurth KH, Fossa SD et al. Early versus delayed endocrine treatment of pN1-3M0 prostate cancer without local treatment of the primary tumor: result of the EORTC trial 30846 - a phase III study. J Urol 2004; 172: 923-927
40. Siewert JR, Rothmund M, Schumpelick V Hrsg. Praxis der Viszeralchirurgie: Onkologische Chirurgie. 2. Aufl. Heidelberg: Springer; 2006
41. Siewert JR. Lymphadenektomie - Ein Glaubensbekenntnis? Chirurg 2007; 78: 181
42. Sugarbaker EV, Cohen AM, Ketcham AS. Do metastases metastasize? Annals Surg 1971; 174: 161-166
43. Tait CR, Dodwell D, Horgan K. Do metastases metastasize? J Pathol 2004; 203: 515-518
44. Tumorregister München, http://www.tumorregister-muenchen.de/ facts/specific-analysis.html; Stand: 19.11.2008
45. Van de Vijver MJ, He YD, van't Veer LJ et al. A gene expression signature as a predictor of survival in breast cancer. N Engl J Med 2002; 347: 1999
46. Veronesi U, Marubini E, Mariani L et al. The dissection of internal mammary nodes does not improve the survival of breast cancer patients. 30-year results of a randomised trial. Eur J Cancer 1999; 35: 1320
47. Wang Y, Klijn JGM, Zhang Y et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 2005; 365: 679
48. Weinberg RA Hrsg. The Biology of Cancer. New York: Garland Science; 2007 (Chapter 14)
49. Weyers W. Excision of melanoma in historical perspective: Triumph of irrationality for nearly a century. History 1997; 3: 238
50. Wong SL, Hong JM, Hollenbeck BK et al. Hospital lymph node examination rates and survival after resection for colon cancer. JAMA 2007; 298: 2149-2154