Behavioral effects of LPS in adult, middle-aged and aged mice

Physiology and Behavior

Volumn 96, Issue 2, 2009, Pages 328-332

  Kinoshita, Denise ^a   Cohn, Daniel Wagner Hamada ^a   Costa Pinto, Frederico Azevedo ^a   de Sá Rocha, Luiz Carlos ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aging process; Elevated plus maze; LPS; Open field; Sickness behavior

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE;

AGED; AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ILLNESS BEHAVIOR; LOCOMOTION; MAZE TEST; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL;

AGING; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; EXPLORATORY BEHAVIOR; LIPOPOLYSACCHARIDES; MAZE LEARNING; MICE; MICE, INBRED C3H;

EID: 58149512089     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2008.10.018     Document Type: Article

References (18)

1. Hart B.L. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 12 (1988) 123-137
2. Blatteis C.M. Endotoxic fever: new concepts of its regulation suggest new approaches to its management. Pharmacol Ther 111 (2006) 194-223
3. Dantzer R. Innate immunity at the forefront of psychoneuroimmunology. Brain Behav Imm 18 (2004) 1-6
4. Johnson R.W. The concept of sickness behavior: a brief chronological account of four key discoveries. Vet Immunol Immunopathol 87 (2002) 443-450
5. Aubert A. Sickness and behavior in animals: a motivational perspective. Neurosci Biobehav Rev 23 (1999) 1029-1036
6. Dantzer R. Cytokine-induced sickness behavior: where do we stand?. Brain Behav Imm 15 (2001) 7-24 2001
7. Ginaldi L., Loreto M.F., Corsi M.P., Modesti M., and De Martinis M. Immunosenescence and infectious diseases. Microbes Infect 3 (2001) 851-857
8. Kelley A.E. Locomotor activity and exploration. In: Haaren F.V. (Ed). Methods in behavioral pharmacology (1993), Elsevier Science, New York 499-518
9. Lister R.G. The use of plus-maze to measure anxiety in the mouse. Psychopharmacology (Berl) 92 (1978) 180-185
10. Pellow S., Chopin S.E., File S.E., and Briley M. Validation of open:closed arms entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14 (1985) 149-167
11. Chorinchath B.B., Kong L.Y., Mao L., and McCallum R.E. Age-associated differences in TNF-α and nitric oxide production in endotoxic mice. J Immunol 156 (1996) 1525-1530
12. McCarthy D.O., Kiuger M.J., and Vander A.J. Suppression of food intake during infection: is interleukin-1 involved?. Am J Clin Nutr 42 (1985) 1179-1182
13. Godbout J.P., Chen J., Abraham J., Richwine A.F., Berg B.M., Kelley K.W., et al. Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system. FASEB J 19 (2005) 1329-1331
14. Nava F., and Carta G. Repeated lipopolysaccharide administration produces tolerance to anorexia and fever but not to inhibition of thirst in rat. Int J Immunopharmacol 22 11 (2000) 943-953
15. Engeland C.G., Nielsen D.V., Kavaliers M., and Ossenkopp K.P. Locomotor activity changes following lipopolysaccharide treatment in mice: a multivariate assessment of behavioral tolerance. Physiol Behav 72 (2001) 481-491
16. Nelson K.P., Marks N.L., Heyen J.R.R., and Johnson R.W. Behavior of adult and aged mice after central injection of Interleukin 1-ß. Physiol Behav 66 (1999) 673-679
17. Cohn D.W.H., and Sá-Rocha L.C. Differential effects of lipopolysaccharide in the social behavior of dominant and submissive mice. Physiol Behav 87 (2006) 932-937
18. Swiergiel A.H., and Dunn A.J. Effects of interleukin-1β and lipopolysaccharide on behavior of mice in the elevated plus-maze and open field tests. Pharmacol Biochem Behav 86 (2007) 651-659