Aldosterone activates NF-κB in the collecting duct

Journal of the American Society of Nephrology

Volumn 20, Issue 1, 2009, Pages 131-144

  Leroy, Valérie ^a,b   De Seigneux, Sophie ^a   Agassiz, Victor ^a   Hasler, Udo ^a   Rafestin Oblin, Marie Edith ^c   Vinciguerra, Manlio ^a   Martin, Pierre Yves ^a   Féraille, Eric ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MINERALOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; SPIRONOLACTONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; I KAPPA B ALPHA GENE; INTERLEUKIN 1BETA GENE; INTERLEUKIN 6 GENE; KIDNEY COLLECTING TUBULE; MALE; MONOCYTE CHEMOATTRACTANT PROTEIN 1 GENE; NONHUMAN; PLASMINOGEN ACTIVATOR INHIBITOR 1 GENE; PRIORITY JOURNAL; RAT; SERUM AND GLUCOCORTICOID REGULATED KINASE 1 GENE; TRANSCRIPTION INITIATION;

EID: 58149510602     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2008020232     Document Type: Article

References (62)

1. Marney AM, Brown NJ: Aldosterone and end-organ damage. Clin Sci (Lond) 113: 267-278, 2007
2. Ishizawa K, Izawa Y, Ito H, Miki C, Miyata K, Fujita Y, Kanematsu Y, Tsuchiya K, Tamaki T, Nishiyama A, Yoshizumi M: Aldosterone stimulates vascular smooth muscle cell proliferation via big mitogen-activated protein kinase 1 activation. Hypertension 46: 1046-1052, 2005
3. Huang W, Xu C, Kahng KW, Noble NA, Border WA, Huang Y: Aldosterone and TGF-β1 synergistically increase PAI-1 and decrease matrix degradation in rat renal mesangial and fibroblast cells. Am J Physiol Renal Physiol 294: F1287-F1295, 2008
4. Mathew JT, Patni H, Chaudhary AN, Liang W, Gupta A, Chander PN, Ding G, Singhal PC: Aldosterone induces mesangial cell apoptosis both in vivo and in vitro. Am J Physiol Renal Physiol 295: F73-F81, 2008
5. Grossmann C, Gekle M: Non-classical actions of the mineralocorticoid receptor: Misuse of EGF receptors? Mol Cell Endocrinol 277: 6-12, 2007
6. Callera GE, Touyz RM, Tostes RC, Yogi A, He Y, Malkinson S, Schiffrin EL: Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src. Hypertension 45: 773-779, 2005
7. Terada Y, Kobayashi T, Kuwana H, Tanaka H, Inoshita S, Kuwahara M, Sasaki S: Aldosterone stimulates proliferation of mesangial cells by activating mitogen-activated protein kinase 1/2, cyclin D1, and cyclin A. J Am Soc Nephrol 16: 2296-2305, 2005
8. Brown NJ, Kim KS, Chen YQ, Blevins LS, Nadeau JH, Meranze SG, Vaughan DE: Synergistic effect of adrenal steroids and angiotensin II on plasminogen activator inhibitor-1 production. J Clin Endocrinol Metab 85: 336-344, 2000
9. Li X, Meng Y, Wu P, Zhang Z, Yang X: Angiotensin II and aldosterone stimulating NF-kappaB and AP-1 activation in hepatic fibrosis of rat. Regul Pept 138: 15-25, 2007
10. Neves MF, Amiri F, Virdis A, Diep QN, Schiffrin EL: Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy. Can J Physiol Pharmacol 83: 999-1006, 2005
11. Vallon V, Wyatt AW, Klingel K, Huang DY, Hussain A, Berchtold S, Friedrich B, Grahammer F, Belaiba RS, Gorlach A, Wulff P, Daut J, Dalton ND, Ross J Jr, Flogel U, Schrader J, Osswald H, Kandolf R, Kuhl D, Lang F: SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med 84: 396-404, 2006
12. Terada Y, Kuwana H, Kobayashi T, Okado T, Suzuki N, Yoshimoto T, Hirata Y, Sasaki S: Aldosterone-stimulated SGK1 activity mediates profibrotic signaling in the mesangium. J Am Soc Nephrol 19: 238-309, 2008
13. Hasler U, Nielsen S, Feraille E, Martin PY: Posttranscriptional control of aquaporin-2 abundance by vasopressin in renal collecting duct principal cells. Am J Physiol Renal Physiol 290: F177-F187, 2006
14. Ghosh S, Karin M: Missing pieces in the NF-kappaB puzzle. Cell 109[Suppl]: S81-S96, 2002
15. Gerondakis S, Grossmann M, Nakamura Y, Pohl T, Grumont R: Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: Transgenics and knockouts. Oncogene 18: 6888-68895, 1999
16. Baines DL, Janes M, Newman DJ, Best OG: Oxygen-evoked changes in transcriptional activity of the 5′-flanking region of the human amiloride-sensitive sodium channel (alphaENaC) gene: Role of nuclear factor kappaB. Biochem J 364: 537-545, 2002
17. Lebowitz J, Edinger RS, An B, Perry CJ, Onate S, Kleyman TR, Johnson JP: IKKβ modulation of ENaC activity. J Biol Chem 279: 41985-41990, 2004
18. Vinciguerra M, Hasler U, Mordasini D, Roussel M, Capovilla M, Ogier-Denis E, Vandewalle A, Martin PY, Feraille E: Cytokines and sodium induce protein kinase A-dependent cell-surface Na,K-ATPase recruitment via dissociation of NF-κB/IκB/protein kinase A catalytic subunit complex in collecting duct principal cells. J Am Soc Nephrol 16: 2576-2585, 2005
19. Chiao P, Miyamato S, Verma I: Autoregulation of IκBα activity. Proc Natl Acad Sci U S A 91: 28-32, 1994
20. Ping D, Jones PL, Boss JM: TNF regulates the in vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene. Immunity 4: 455-469, 1996
21. Ghosh S, May MJ, Kopp EB: NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses. Annu Rev Immunol 16: 225-260, 1998
22. Zhang L, Cui R, Cheng X, Du J: Antiapoptotic effect of serum and glucocorticoid-inducible protein kinase is mediated by novel mechanism activating IκB kinase. Cancer Res 65: 457-464, 2005
23. + absorption in mammalian principal cortical collecting duct cells. Mol Pharmacol 62: 1306-1313, 2002
24. Bens M, Vallet V, Cluzeaud F, Pascual-Letallec L, Kahn A, Rafestin-Oblin ME, Rossier BC, Vandewalle A: Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line. J Am Soc Nephrol 10: 923-934, 1999
25. Gaeggeler HP, Gonzalez-Rodriguez E, Jaeger NF, Loffing-Cueni D, Norregaard R, Loffing J, Horisberger JD, Rossier BC: Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line. J Am Soc Nephrol 16: 878-891, 2005
26. Hayden MS, Ghosh S: Signaling to NF-B. Genes Dev 18: 2195-2224, 2004
27. Ruben SM, Klement JF, Coleman TA, Maher M, Chen CH, Rosen CA: I-Rel: A novel rel-related protein that inhibits NF-κB transcriptional activity. Genes Dev 6: 745-760, 1992
28. Marienfeld R, Berberich-Siebelt F, Berberich I, Denk A, Serfling E, Neumann M: Signal-specific and phosphorylation-dependent RelB degradation: A potential mechanism of NF-κB control. Oncogene 20: 8142-8147, 2001
29. Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W, Haegeman G: p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κ B p65 transactivation mediated by tumor necrosis factor. J Biol Chem 273: 3285-3290, 1998
30. + transport in cortical collecting duct cells. J Am Soc Nephrol 16: 2279-2287, 2005
31. Artunc F, Amann K, Nasir O, Friedrich B, Sandulache D, Jahovic N, Risler T, Vallon V, Wulff P, Kuhl D, Lang F: Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. J Mol Med 84: 737-746, 2006
32. Feng Y, Wang Q, Wang Y, Yard B, Lang F: SGK1-mediated fibronectin formation in diabetic nephropathy. Cell Physiol Biochem 16: 237-244, 2005
33. Perkins ND: Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene 25: 6717-6730, 2006
34. De Bosscher K, Vanden Berghe W, Haegeman G: Cross-talk between nuclear receptors and nuclear factor kappaB. Oncogene 25: 6868-6886, 2006
35. Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr: Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270: 283-286, 1995
36. de Haij S, Woltman AM, Bakker AC, Daha MR, van Kooten C: Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids. Br J Pharmacol 137: 197-204, 2002
37. Newton R, Holden NS: Separating transrepression and transactivation: A distressing divorce for the glucocorticoid receptor? Mol Pharmacol 72: 799-809, 2007
38. Boulkroun S, Fay M, Zennaro M-C, Escoubet B, Jaisser F, Blot-Chabaud M, Farman N, Courtois-Coutry N: Characterization of rat NDRG2 (N-myc downstream regulated gene 2), a novel early mineralocorticoid-specific induced gene. J Biol Chem 277: 31506-31515, 2002
39. + transport by rat collecting duct cells in culture: Differences between glucocorticoid and mineralocorticoid hormones. J Clin Invest 90: 1370-1378, 1992
40. + absorption and stimulate anion secretion by IMCD cells. Am J Physiol 275: F946-F954, 1998
41. Pacha J, Frindt G, Antonian L, Silver RB, Palmer LG: Regulation of Na channels of the rat cortical collecting tubule by aldosterone. J Gen Physiol 102: 25-42, 1993
42. Greene E, Kren S, Hostetter T: Role of aldosterone in the remnant kidney model in the rat. J Clin Invest 98: 1063-1068, 1996
43. Hene RJ, Boer P, Koomans HA, Dorhout Mees EJ: Plasma aldosterone concentrations in chronic renal disease. Kidney Int 21: 98-101, 1982
44. Reams GP, Bauer JH: Effect of enalapril in subjects with hypertension associated with moderate to severe renal dysfunction. Arch Intern Med 146: 2145-2148, 1986
45. Han S-Y, Kim C-H, Kim H-S, Jee Y-H, Song H-K, Lee M-H, Han K-H, Kim H-K, Kang Y-S, Han J-Y, Kim Y-S, Cha D-R: Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. J Am Soc Nephrol 17: 1362-1372, 2006
46. Fujisawa G, Okada K, Muto S, Fujita N, Itabashi N, Kusano E, Ishibashi S: Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. Kidney Int 66: 1493-1502, 2004
47. Aldigier JC, Kanjanbuch T, Ma LJ, Brown NJ, Fogo AB: Regression of existing glomerulosclerosis by inhibition of aldosterone. J Am Soc Nephrol 16: 3306-3314, 2005
48. Bianchi S, Bigazzi R, Campese VM: Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease. Kidney Int 70: 2116-2123, 2006
49. Amasheh S, Barmeyer C, Koch CS, Tavalali S, Mankertz J, Epple HJ, Gehring MM, Florian P, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD: Cytokine-dependent transcriptional down-regulation of epithelial sodium channel in ulcerative colitis. Gastroenterology 126: 1711-1720, 2004
50. Fukuda N, Jayr C, Lazrak A, Wang Y, Lucas R, Matalon S, Matthay MA: Mechanisms of TNF-α stimulation of amiloride-sensitive sodium transport across alveolar epithelium. Am J Physiol Lung Cell Mol Physiol 280: L1258-L1265, 2001
51. Sakairi Y, Ando Y, Tabei K, Kusano E, Asano Y: Interleukin-1 inhibits sodium and water transport in rabbit cortical collecting duct. Am J Physiol Renal Physiol 266: F674-F680, 1994
52. de Seigneux S, Leroy V, Ghzili H, Rousselot M, Nielsen S, Rossier BC, Martin P-Y, Feraille E: NF-κB inhibits sodium transport via down-regulation of SGK1 in renal collecting duct principal cells. J Biol Chem 283: 25671-25681, 2008
53. Hasler U, Leroy V, Jeon US, Bouley R, Dimitrov M, Kim JA, Brown D, Kwon HM, Martin PY, Feraille E: NF-κB modulates aquaporin-2 transcription in renal collecting duct principal cells. J Biol Chem 283: 28095-28105, 2008
54. Hasler U, Mordasini D, Bianchi M, Vandewalle A, Feraille E, Martin PY: Dual influence of aldosterone on AQP2 expression in cultured renal collecting duct principal cells. J Biol Chem 278: 21639-21648, 2003
55. + transport by AVP is independent of PKA phosphorylation of the Na-K-ATPase in collecting duct principal cells. Am J Physiol Renal Physiol 289: F1031-F1039, 2005
56. Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A: IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation. Science 278: 860-866, 1997
57. Oyama T, Ran S, Ishida T, Nadaf S, Kerr L, Carbone DP, Gabrilovich DI: Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-κB activation in hemopoietic progenitor cells. J Immunol 160: 1224-1232, 1998
58. Feraille E, Carranza ML, Rousselot M, Favre H: Insulin enhances sodium sensitivity of Na-K-ATPase in isolated rat proximal convoluted tubule. Am J Physiol Renal Physiol 267: F55-F62, 1994
59. Hasler U, Vinciguerra M, Vandewalle A, Martin PY, Feraille E: Dual effects of hypertonicity on aquaporin-2 expression in cultured renal collecting duct principal cells. J Am Soc Nephrol 16: 1571-1582, 2005
60. Hasler U, Mordasini D, Bens M, Bianchi M, Cluzeaud F, Rousselot M, Vandewalle A, Feraille E, Martin PY: Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells. J Biol Chem 277: 10379-10386, 2002
61. Fujita T, Nolan GP, Liou HC, Scott ML, Baltimore D: The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-κB p50 homodimers. Genes Dev 7: 1354-1363, 1993
62. Ryser S, Fujita T, Tortola S, Piuz I, Schlegel W: The rate of c-fos transcription in vivo is continuously regulated at the level of elongation by dynamic stimulus-coupled recruitment of positive transcription elongation factor b. J Biol Chem 282: 5075-5084, 2007