Combined chelation of bi-functional bis-hydroxypiridinone and mono-hydroxypiridinone: Synthesis, solution and in vivo evaluation

Journal of Inorganic Biochemistry

Volumn 103, Issue 2, 2009, Pages 288-298

  Gama, Sofia ^a   Gil, Marco ^a   Gano, Lurdes ^b   Farkas, Etelka ^c   Amelia Santos M ^a  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^b INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Chelation therapy; Combined chelation; Hydroxypyridinonate complexes; Hydroxypyridinone; Ternary complex

Indexed keywords

GALLIUM CITRATE GA 67; IRON; PYRIDONE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CHELATION; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; MOUSE; NONHUMAN; POTENTIOMETRY; SPECTROPHOTOMETRY;

ALUMINUM; ANIMALS; FEMALE; GALIUM; GLYCINE; IRON; IRON CHELATING AGENTS; LIGANDS; MICE; PYRIDONES; TISSUE DISTRIBUTION;

MUS;

EID: 58149498315     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2008.10.020     Document Type: Article

References (48)

1. Andrews N.C. New Eng. J. Med. 341 (1999) 1986-1995
2. Crisponi G., and Remelli M. Coord. Chem. Rev. 252 (2008) 1225-1240
3. Kiss T., Gajda-Schrantz K., and Zatta P. In: Sigel A., Sigel H., and Sigel R.K.O. (Eds). Metal Ions and Life Sciences, Neurodegenerative Diseases and Metal Ions (2006), Wiley & Sons, Chichester 371-393
4. Liu Z.D., and Hider R.C. Coord. Chem. Rev. 232 (2002) 151-171
5. Liu D.Y., Liu Z.D., and Hider R.C. Best Pract. Res. Clin. Haematol. 15 (2002) 369-384
6. Florence A.L., Gauthier A., Ward R.J., and Crichton R.R. Neurodegeneration 4 (1995) 449-455
7. Wonke B., Wright C., and Holffbrand A.V. Br. J. Haematol. 103 (1998) 361-364
8. Kontoghiorghes G.J. Hemoglobin 30 (2006) 329-347
9. Kontoghiorghes G.J. Curr. Med. Chem. 12 (2005) 2661-2662
10. Kattamis A. Ann. N. Y. Acad. Sci. 1054 (2005) 175-182
11. Esparza J.L., Gómez M., Domingo J.L., Del Castillo D., and Hernandez M. Pharmacol. Toxicol. 87 (2000) 33-38
12. Kruck T.P., Cui J.G., Percy M.E., and Lukiw W.J. Cell. Mol. Neurobiol. 24 (2004) 443-459
13. Anderson C.J., and Welch M.J. Chem. Rev. 99 (1999) 2219-2234
14. Thompson K.H., Barta C.A., and Orvig C. Chem. Soc. Rev. 35 (2006) 545-556
15. Santos M.A. Coord. Chem. Rev. 228 (2002) 187-203
16. R. Grazina, L. Gano, J. Sebestik, M. A. Santos, J. Inorg. Biochem. (2008) in press.
17. Santos M.A., Gama S., Gano L., Cantinho G., and Farkas E. Dalton Trans. 21 (2004) 3772-3781
18. Piyamongkol S., Zhou T., Liu Z.D., Khodr H.H., and Hider R.C. Tetrahedron Lett. 46 (2005) 1333-1336
19. Santos M.A., Gil M., Marques S., Gano L., Cantinho G., and Chaves S. J. Inorg. Biochem. 92 (2002) 43-54
20. Santos M.A., Gil M., Gano L., and Chaves S. J. Biol. Inorg. Chem. 10 (2005) 564-580
21. Green D.E., Ferreira C.L., Stick R.V., Patrick B.O., Adam M.J., and Orvig C. Bioconj. Chem. 16 (2005) 1597-1609
22. Santos M.A. Coord. Chem. Rev. 252 (2008) 1213-1224
23. Patrick G.L. An Introduction to Medicinal Chemistry (2004), Oxford University Press Inc., New York
24. De Costa B.R., Radesca L., Di Paolo L., and Bowen W.D. J. Med. Chem. 35 (1992) 28-47
25. De Costa B.R., He X., Linders J.T.M., Dominguez C., Gu Z.Q., Williams W., and Bowen W.D. J. Med. Chem. 36 (1993) 2311-2320
26. John C.S., Vilner B.J., Geyer B.C., Moody T., and Bowen W.D. Cancer Res. 59 (1999) 4578-4583
27. Armarego W.L.F., and Perrin D.D. Purification of Laboratory Chemicals (1999), Butterworth Heinemann Press, Oxford
28. Gran G. Acta Chem. Scan. 4 (1950) 559-577
29. Santos M.A., Marques S.M., Rossello A., Tuccinardi T., Carelli P., and Panelli L. Bioorg. Med. Chem. 14 (2006) 7539-7550
30. Irving H.M., Miles M.G., and Pettit L.D. Anal. Chim. Acta 38 (1967) 475-488
31. Baes C.F., and Mesmer R.E. The Hydrolysis of Cations (1976), Wiley, New York
32. Farkas E., Kozma E., Kiss T., Toth I., and Kurzak B. J. Chem. Soc. Dalton Trans. (1995) 477-481
33. Ohman L.O., and Forsling W. Acta Chem. Scan. Ser. A - Phys. Inorg. Chem. 35 (1981) 795-802
34. Zékány L., and Nagypál I. Computational Methods for the Determination of Stability Constants (1985), Plenum Press, New York
35. Leo A., Hansch C., and Elkins D. Chem. Rev. 71 (1971) 525-616
36. Glasoe P.K., and Long F.A. J. Phys. Chem. 64 (1960) 188-190
37. Gans P., Sabatini A., and Vacca A. J. Chem. Soc. Dalton Trans. (1985) 1195-1200
38. Clarke E.T., and Martell A.E. Inorg. Chim. Acta 191 (1992) 57-63
39. Clarke E.T., and Martell A.E. Inorg. Chim. Acta 196 (1992) 185-194
40. A.E. Martell, R.M. Smith, R.J. Motekaitis, Critically Selected Stability Constants of Metal Complexes Database, College Station TX, Version 4, 1997.
41. Farkas E., Enyedy E.A., and Csoka H. Polyhedron 18 (1999) 2391-2398
42. Motekaitis R.J., Sun Y., and Martell A.E. Inorg. Chim. Acta 159 (1989) 29-39
43. Motekaitis R.J., and Martell A.E. Inorg. Chim. Acta 183 (1991) 71-80
44. Chaves S., Gil M., Marques S., Gano L., and Santos M.A. J. Inorg. Biochem. 97 (2003) 161-172
45. Santos M.A., Grazina R., Neto A.Q., Cantinho G., Gano L., and Patrício L. J. Inorg. Biochem. 97 (2000) 303-311
46. Gunasekera S.W., King L.J., and Lavender P.J. Clin. Chim. Acta 39 (1972) 401-406
47. Larson S.M., Rasey J.S., Allen D.R., and Grunbaum Z. J. Nucl. Med. 20 (1979) 843-846
48. Hara T. Int. J. Nucl. Med. Biol. 1 (1974) 152-154