Mechanisms of cytotoxicity of 2- or 2,6-di-tert-butylphenols and 2-methoxyphenols in terms of inhibition rate constant and a theoretical parameter

Chemosphere

Volumn 74, Issue 5, 2009, Pages 626-632

  Kadoma, Yoshinori ^a   Ito, Shigeru ^a   Atsumi, Toshiko ^b   Fujisawa, Seiichiro ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Cytotoxicity; Inhibition rate constants; QSAR; tert Butyl or methoxy substituted complex phenols; Theoretical parameters

Indexed keywords

ANTI-OXIDANTS; AZOBISISOBUTYRONITRILE; BENZOYL PEROXIDES; BUTYLPHENOL; BUTYLPHENOLS; CARCINOMA CELLS; CURCUMIN; CYTOTOXIC; HOMOLYTIC BONDS; HUMAN GINGIVAL FIBROBLASTS; HUMAN PERIODONTAL LIGAMENT FIBROBLASTS; HUMAN PULP FIBROBLASTS; HUMAN SUBMANDIBULAR GLANDS; INDUCTION PERIODS; INHIBITION RATE CONSTANTS; LINEAR RELATIONSHIPS; METHOXYPHENOLS; ORAL TISSUES; POTENT ANTIOXIDANTS; PRIMARY CELLS; PROMYELOCYTIC LEUKEMIAS; QSAR; QUANTITATIVE STRUCTURES; RADICAL REACTIONS; RADICAL SCAVENGING; SCAVENGING ACTIVITIES; STERIC HINDRANCES; SUBSTITUTED PHENOLS; TERT-BUTYL OR METHOXY-SUBSTITUTED COMPLEX PHENOLS; THEORETICAL PARAMETERS; TUMOR CELLS;

ALDEHYDES; BIOCHEMISTRY; CELL CULTURE; CHEMICAL BONDS; CHEMICAL REACTIONS; FIBROBLASTS; FREE RADICAL POLYMERIZATION; INTERNET PROTOCOLS; IONIZATION POTENTIAL; LIGAMENTS; PHENOLIC RESINS; PHENOLS; POLYMERS; RATE CONSTANTS; REACTION KINETICS; SULFUR COMPOUNDS; TISSUE; TOXICITY; TUMORS;

CYTOTOXICITY;

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 TERT BUTYL PARA CRESOL; 2,4 DI(TERT BUTYL)PHENOL; 2,4,6 TRI TERT BUTYLPHENOL; 3,5 DI TERT BUTYL 4 HYDROXY BENZALDEHYDE; ANTIOXIDANT; BENZOYL PEROXIDE; BUTYLCRESOL; BUTYRONITRILE; CURCUMIN; DIMER; EUGENOL; GUAIACOL; ISOEUGENOL; METHACRYLIC ACID; PHENOL DERIVATIVE; UNCLASSIFIED DRUG; VANILLIN;

ALDEHYDE; ASSAY; INHIBITION; IONIZATION; PHENOLIC COMPOUND; POLYMERIZATION; REACTION RATE; TOXICITY; TUMOR;

ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; ENTHALPY; HUMAN; HUMAN CELL; IONIZATION; MOLECULAR MECHANICS; PARAMETER; POLYMERIZATION; RADICAL REACTION; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANTIOXIDANTS; BENZALDEHYDES; BUTYLATED HYDROXYTOLUENE; CELL LINE, TUMOR; CURCUMIN; EUGENOL; HL-60 CELLS; HUMANS; KINETICS; PHENOLS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58149488773     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.10.039     Document Type: Article

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