Use of Lucilia sericata blowfly maggots in the treatment of diabetic feet threatened with amputation;Zastosowanie jałowych larw muchy plujki Lucilia sericata w leczeniu chorych z zagrożona amputacja stopa cukrzycowa

Acta Angiologica

Volumn 14, Issue 2, 2008, Pages 42-55

  Jarczyk, Grzegorz ^a,d   Jackowski, Marek ^a   Szpila, Krzysztof ^b   Boszek, Grazyna ^a   Kapelaty, Sławomir ^c  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^c Department of Radiology   (Poland)

^d NONE   (Poland)

Author keywords

Diabetic foot; Larval therapy

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ANKLE BRACHIAL INDEX; ARTICLE; ATHEROSCLEROSIS; CASE REPORT; CLINICAL EFFECTIVENESS; DEBRIDEMENT; DIABETIC FOOT; DOPPLER FLOWMETRY; FEMALE; HUMAN; LEG AMPUTATION; MAGGOT; MAGGOT THERAPY; MALE; MICROBIOLOGICAL EXAMINATION; SEX DIFFERENCE; TREATMENT OUTCOME; VASCULAR DISEASE; WOUND CARE; WOUND DRESSING;

EID: 58149479412     PISSN: 1234950X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Frygberg RG (1999) Epidemiology of diabetic foot: ulceration and amputation. Adv Wound Pare, 12: 139-141.
2. Jarczyk G (2006) Biochirurgia: Lucilia sericata - mały, wielki chirurg. Pol Przeg Chir, 78: 1513-1529.
3. Baer WS (1931) The treatment of chronic osteomyelitis with the maggot (larva of the blowfly). J Bone Jt Surg, 13: 438-475.
4. Robinson W (1935) Progress of maggot therapy in the United States and Canada in the treatment of suppurative diseases. Am J Surg, 29: 67-71.
5. Sherman RA (2003) Maggot therapy for treating diabetic foot ulcers unresponsive to conventional therapy. Diabetes Care, 26: 446-451.
6. Mumcuoglu KY, Ingber A, Gilead L et al (1998) Maggot therapy for the treatment of diabetic foot ulcers. Diabetes Care, 21: 2030-2031.
7. Bowling FL, Salgami EV, Boulton AJ (2007) Larval therapy: a novel treatment in eliminating methicillin-resistant Staphylococcus aureus from diabetic foot ulcers. Diabetes Care, 30: 370-371.
8. Yates I, Fox M, Crewdson M, Woodyer AB (2003) Larvae - A key member of the multidisciplinary foot team? Diabetic Foot, 6: 166-171.
9. Armstrong DG, Lavery LA, Harkless LB (1998) Validation of a diabetic wound classification system: the contribution of depth, infection and ischemia to risk of amputation. Diabetes Care, 21: 855-859.
10. Brem H, Sheehan P, Boulton AJM (2004) Protocol for treatment of diabetic foot ulcers. Am J Surg 187 (suppl I): S1-S10.
11. Cavanagh PR, Lipsky BA, Bradbury AW, Botek G (2005) Treatment for diabetic foot ulcers. Lancet, 366: 1725-1735.
12. Edmonds M, Foster A (2004) The use of antibiotics in the diabetic foot. Am J Surg, 187: 25S-28S.
13. Resnick HE, Valsania P, Phillips CL (1999) Diabetes mellitus and nontraumatic lower extremity amputation in black and white americans. Arch Intern Med, 159: 2470-2475.
14. Nigam Y, Bexfield A, Thomas S, Ratcliffe A (2006) Maggot therapy; The science and implication for CAM part II-Maggots combat infection. Evid Based Complement Alternat Med, 3: 303-308.
15. Chambers L, Woodrow S, Brown AP et al (2003) Degradation of extracellular matrix components by defined proteinases from the greenbottle larva Lucilia sericata used for the clinical debridement of non-healing wounds. Br J Dermatol, 1: 14-23.
16. Nigam Y, Bexfield A, Thomas S, Ratcliffe A (2006) Maggot therapy; The science and implication for CAM part I - History and bacterial resistance. Evid Based Complement Alternat Med, 2: 223-227.
17. Wayman J, Nirojogi V, Walker A, Sowinski A, Walker MA (2000) The cost effectiveness of larval therapy in venous ulcers. J Tissue Viability, 3: 91-94.
18. Sherman RA (1998) Maggot therapy in modern medicine. Infect Med, 15: 651-656.
19. Armstrong DG, Salas P, Short B et al (2005) Maggot therapy in "lower-extremity hospice" wound care: fewer amputations and more antibiotic free days. J Am Podiatr Med Assoc, 95: 254-257.
20. Hafner J, Schaad I, Schneider E, Seifert B, Burg G, Casina PC (2000) Leg ulcers in peripheral arterial disease (arterial leg ulcers): Impared wound healing above the threshold of chronic critical limb ischemia. J Am Acad Dermatol, 43: 1001-1008.
21. Steenvoorde P, Jacobi CE, Oskam J (2007) The results of maggot dedridement therapy in the ischemic leg: A study on 89 patients with 89 wounds on the lower leg treated with maggots. Internet J Surg, 9: 1-4.
22. Marso SP, Hiatt WR (2006) Peripheral arterial disease in patients with diabetes. J Am Coll Cardiol, 47: 921-929.
23. Sheahan MG, Hamdan AD, Veraldi JR et al (2005) Lower extremity minor amputations: The roles of diabetes mellitus and timing of revascularization. J Vasc Surg, 42: 476-480.
24. Browne AC, Vearncombe M, Sibbald RG (2001) High bacterial load in asymptomatic diabetic patients with neurotrophic ulcers retards wound healing after application of Dermagraft. Ostomy Wound Manage, 47: 44-49.
25. Robson MC (1997) Wound infection: a failure of wound healing caused by an imbalance of bacteria. Surg Clin North Am, 3: 637-650
26. Xu L, McLennan SV, Lo L et al (2007) Bacterial load predicts healing rate in neuropathic diabetic foot ulcers. Diabetes Care, 30: 378-380.
27. Bowler PG, Duerden BI, Amstrong DG (2001) Wound microbiology and associated approaches to wound management. Clin Microbiol Rev, 14: 244-269.
28. Kievit TR, Iglewski BH (2000) Bacterial quorum sensing in pathogenic relationships. Infect Immun, 9: 4839-4849.
29. Suga H, Smith KM (2003) Molecular mechanism of bacterial quorum sensing as a new drug target. Curr Opin Chem Biol, 7: 586-591.
30. Sherman RA, Shimoda KJ (2004) Presurgical maggot debridement of soft tissue wounds is associated with decreased rates of postoperative infection. CID, 39: 1067-1070.
31. Thomas S, Andrews AM, Hay NP, Bourgoise S (1999) The antimicrobial activity of maggot secretions: results of preliminary study. J Tissue Viability, 9: 127-132.
32. Lodge A, Jones M, Thomas S (2007) Maggots 'n' chips: a novel approach to the treatment of diabetic ulcers. BJCN, 11: 23-26.
33. Jukema GN, Menon AG, Bernards AT, Steenvoorde P, Taheri Rastegar A, van Dissel JT (2002) Amputation-sparing treatment by nature: "Surgical" maggots revisited. CID, 35: 1566-1571.
34. Steenvoorde P, Buddhing TJ, van Engeland A, Oskam J (2005) Maggot therapy and "Yuk" factor: An issue for the patient? Wound Repair Regen, 13: 350-352.
35. Edmonds M, Foster AVM, Vowden P (2006) Opracowanie łożyska rany w przypadku owrzodzeń stopy cukrzycowej. Leczenie Ran, 3 (supl. I): S9-S14.