메뉴 건너뛰기




Volumn 158, Issue 1, 2009, Pages 177-188

Leaky synapses: Regulation of spontaneous neurotransmission in central synapses

Author keywords

cholesterol; miniature synaptic transmission; SNARE; spontaneous neurotransmission; synaptic vesicle recycling; synaptotagmin

Indexed keywords

CHOLESTEROL; GLUTAMIC ACID; NEUROTRANSMITTER;

EID: 58149473293     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.03.028     Document Type: Review
Times cited : (43)

References (108)
  • 1
    • 0035185381 scopus 로고    scopus 로고
    • Intraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junction
    • Angleson J.K., and Betz W.J. Intraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junction. J Neurophysiol 85 (2001) 287-294
    • (2001) J Neurophysiol , vol.85 , pp. 287-294
    • Angleson, J.K.1    Betz, W.J.2
  • 2
    • 84944495555 scopus 로고
    • A study of supersensitivity in denervated mammalian skeletal muscle
    • Axelsson J., and Thesleff S. A study of supersensitivity in denervated mammalian skeletal muscle. J Physiol 147 (1959) 178-193
    • (1959) J Physiol , vol.147 , pp. 178-193
    • Axelsson, J.1    Thesleff, S.2
  • 4
    • 0035146647 scopus 로고    scopus 로고
    • Modulation of spontaneous quantal release of neurotransmitters in the hippocampus
    • Bouron A. Modulation of spontaneous quantal release of neurotransmitters in the hippocampus. Prog Neurobiol 63 (2001) 613-635
    • (2001) Prog Neurobiol , vol.63 , pp. 613-635
    • Bouron, A.1
  • 5
    • 0029093329 scopus 로고
    • Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila
    • Broadie K., Prokop A., Bellen H.J., O'Kane C.J., Schulze K.L., and Sweeney S.T. Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila. Neuron 15 (1995) 663-673
    • (1995) Neuron , vol.15 , pp. 663-673
    • Broadie, K.1    Prokop, A.2    Bellen, H.J.3    O'Kane, C.J.4    Schulze, K.L.5    Sweeney, S.T.6
  • 7
    • 0036897560 scopus 로고    scopus 로고
    • Quantal events shape cerebellar interneuron firing
    • Carter A.G., and Regehr W.G. Quantal events shape cerebellar interneuron firing. Nat Neurosci 5 (2002) 1309-1318
    • (2002) Nat Neurosci , vol.5 , pp. 1309-1318
    • Carter, A.G.1    Regehr, W.G.2
  • 8
    • 0035826727 scopus 로고    scopus 로고
    • SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis
    • Chamberlain L.H., Burgoyne R.D., and Gould G.W. SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis. Proc Natl Acad Sci U S A 98 (2001) 5619-5624
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5619-5624
    • Chamberlain, L.H.1    Burgoyne, R.D.2    Gould, G.W.3
  • 12
    • 0020323440 scopus 로고
    • Discrepancies between spontaneous and evoked synaptic potentials at normal, regenerating and botulinum toxin poisoned mammalian neuromuscular junctions
    • Colmeus C., Gomez S., Molgo J., and Thesleff S. Discrepancies between spontaneous and evoked synaptic potentials at normal, regenerating and botulinum toxin poisoned mammalian neuromuscular junctions. Proc R Soc Lond B Biol Sci 215 (1982) 63-74
    • (1982) Proc R Soc Lond B Biol Sci , vol.215 , pp. 63-74
    • Colmeus, C.1    Gomez, S.2    Molgo, J.3    Thesleff, S.4
  • 13
    • 7944229497 scopus 로고    scopus 로고
    • Synaptobrevin is essential for fast synaptic-vesicle endocytosis
    • Deak F., Schoch S., Liu X., Sudhof T.C., and Kavalali E.T. Synaptobrevin is essential for fast synaptic-vesicle endocytosis. Nat Cell Biol 6 (2004) 1102-1108
    • (2004) Nat Cell Biol , vol.6 , pp. 1102-1108
    • Deak, F.1    Schoch, S.2    Liu, X.3    Sudhof, T.C.4    Kavalali, E.T.5
  • 14
    • 33745800098 scopus 로고    scopus 로고
    • Structural determinants of synaptobrevin 2 function in synaptic vesicle fusion
    • Deak F., Shin O.H., Kavalali E.T., and Sudhof T.C. Structural determinants of synaptobrevin 2 function in synaptic vesicle fusion. J Neurosci 26 (2006) 6668-6676
    • (2006) J Neurosci , vol.26 , pp. 6668-6676
    • Deak, F.1    Shin, O.H.2    Kavalali, E.T.3    Sudhof, T.C.4
  • 15
    • 0032521343 scopus 로고    scopus 로고
    • Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-synaptobrevin
    • Deitcher D.L., Ueda A., Stewart B.A., Burgess R.W., Kidokoro Y., and Schwarz T.L. Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-synaptobrevin. J Neurosci 18 (1998) 2028-2039
    • (1998) J Neurosci , vol.18 , pp. 2028-2039
    • Deitcher, D.L.1    Ueda, A.2    Stewart, B.A.3    Burgess, R.W.4    Kidokoro, Y.5    Schwarz, T.L.6
  • 16
    • 0027501003 scopus 로고
    • Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
    • Dietschy J.M., Turley S.D., and Spady D.K. Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 34 (1993) 1637-1659
    • (1993) J Lipid Res , vol.34 , pp. 1637-1659
    • Dietschy, J.M.1    Turley, S.D.2    Spady, D.K.3
  • 17
    • 0030003658 scopus 로고    scopus 로고
    • Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse
    • Dittman J.S., and Regehr W.G. Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse. J Neurosci 16 (1996) 1623-1633
    • (1996) J Neurosci , vol.16 , pp. 1623-1633
    • Dittman, J.S.1    Regehr, W.G.2
  • 18
    • 76949136401 scopus 로고
    • Spontaneous subthreshold activity at motor nerve endings
    • Fatt P., and Katz B. Spontaneous subthreshold activity at motor nerve endings. J Physiol 117 (1952) 109-128
    • (1952) J Physiol , vol.117 , pp. 109-128
    • Fatt, P.1    Katz, B.2
  • 23
    • 33745002260 scopus 로고    scopus 로고
    • Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity
    • Fujiwara T., Mishima T., Kofuji T., Chiba T., Tanaka K., Yamamoto A., and Akagawa K. Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity. J Neurosci 26 (2006) 5767-5776
    • (2006) J Neurosci , vol.26 , pp. 5767-5776
    • Fujiwara, T.1    Mishima, T.2    Kofuji, T.3    Chiba, T.4    Tanaka, K.5    Yamamoto, A.6    Akagawa, K.7
  • 25
    • 33745740224 scopus 로고    scopus 로고
    • 2+-dependent release machinery by presynaptic group II mGluRs in rat cerebellar slices
    • 2+-dependent release machinery by presynaptic group II mGluRs in rat cerebellar slices. J Neurophysiol 96 (2006) 86-96
    • (2006) J Neurophysiol , vol.96 , pp. 86-96
    • Glitsch, M.1
  • 26
    • 37849051619 scopus 로고    scopus 로고
    • Spontaneous neurotransmitter release and Ca(2+)-how spontaneous is spontaneous neurotransmitter release?
    • Glitsch M.D. Spontaneous neurotransmitter release and Ca(2+)-how spontaneous is spontaneous neurotransmitter release?. Cell Calcium 43 (2007) 9-15
    • (2007) Cell Calcium , vol.43 , pp. 9-15
    • Glitsch, M.D.1
  • 27
    • 33846612037 scopus 로고    scopus 로고
    • Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool
    • Groemer T.W., and Klingauf J. Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool. Nat Neurosci 10 (2007) 145-147
    • (2007) Nat Neurosci , vol.10 , pp. 145-147
    • Groemer, T.W.1    Klingauf, J.2
  • 28
    • 0035511278 scopus 로고    scopus 로고
    • Limited numbers of recycling vesicles in small CNS nerve terminals: implications for neural signaling and vesicular cycling
    • Harata N., Pyle J.L., Aravanis A.M., Mozhayeva M., Kavalali E.T., and Tsien R.W. Limited numbers of recycling vesicles in small CNS nerve terminals: implications for neural signaling and vesicular cycling. Trends Neurosci 24 (2001) 637-643
    • (2001) Trends Neurosci , vol.24 , pp. 637-643
    • Harata, N.1    Pyle, J.L.2    Aravanis, A.M.3    Mozhayeva, M.4    Kavalali, E.T.5    Tsien, R.W.6
  • 29
    • 0026471991 scopus 로고
    • The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS
    • Hess D.T., Slater T.M., Wilson M.C., and Skene J.H. The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS. J Neurosci 12 (1992) 4634-4641
    • (1992) J Neurosci , vol.12 , pp. 4634-4641
    • Hess, D.T.1    Slater, T.M.2    Wilson, M.C.3    Skene, J.H.4
  • 31
    • 0032418273 scopus 로고    scopus 로고
    • Different VAMP/synaptobrevin complexes for spontaneous and evoked transmitter release at the crayfish neuromuscular junction
    • Hua S.Y., Raciborska D.A., Trimble W.S., and Charlton M.P. Different VAMP/synaptobrevin complexes for spontaneous and evoked transmitter release at the crayfish neuromuscular junction. J Neurophysiol 80 (1998) 3233-3246
    • (1998) J Neurophysiol , vol.80 , pp. 3233-3246
    • Hua, S.Y.1    Raciborska, D.A.2    Trimble, W.S.3    Charlton, M.P.4
  • 32
    • 34748846347 scopus 로고    scopus 로고
    • A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth
    • Huntwork S., and Littleton J.T. A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth. Nat Neurosci 10 (2007) 1235-1237
    • (2007) Nat Neurosci , vol.10 , pp. 1235-1237
    • Huntwork, S.1    Littleton, J.T.2
  • 33
    • 3042693940 scopus 로고    scopus 로고
    • Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease
    • Hynd M.R., Scott H.L., and Dodd P.R. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochem Int 45 (2004) 583-595
    • (2004) Neurochem Int , vol.45 , pp. 583-595
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 34
    • 0037459076 scopus 로고    scopus 로고
    • Membrane fusion
    • Jahn R., Lang T., and Sudhof T.C. Membrane fusion. Cell 112 (2003) 519-533
    • (2003) Cell , vol.112 , pp. 519-533
    • Jahn, R.1    Lang, T.2    Sudhof, T.C.3
  • 35
    • 33747622293 scopus 로고    scopus 로고
    • SNAREs-engines for membrane fusion
    • Jahn R., and Scheller R.H. SNAREs-engines for membrane fusion. Nat Rev Mol Cell Biol 7 (2006) 631-643
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 631-643
    • Jahn, R.1    Scheller, R.H.2
  • 36
    • 0028801536 scopus 로고
    • Cholesterol for synthesis of myelin is made locally, not imported into brain
    • Jurevics H., and Morell P. Cholesterol for synthesis of myelin is made locally, not imported into brain. J Neurochem 64 (1995) 895-901
    • (1995) J Neurochem , vol.64 , pp. 895-901
    • Jurevics, H.1    Morell, P.2
  • 38
    • 0032981938 scopus 로고    scopus 로고
    • Contribution of active zone subpopulation of vesicles to evoked and spontaneous release
    • Koenig J.H., and Ikeda K. Contribution of active zone subpopulation of vesicles to evoked and spontaneous release. J Neurophysiol 81 (1999) 1495-1505
    • (1999) J Neurophysiol , vol.81 , pp. 1495-1505
    • Koenig, J.H.1    Ikeda, K.2
  • 39
    • 0035341309 scopus 로고    scopus 로고
    • SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis
    • Lang T., Bruns D., Wenzel D., Riedel D., Holroyd P., Thiele C., and Jahn R. SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis. EMBO J 20 (2001) 2202-2213
    • (2001) EMBO J , vol.20 , pp. 2202-2213
    • Lang, T.1    Bruns, D.2    Wenzel, D.3    Riedel, D.4    Holroyd, P.5    Thiele, C.6    Jahn, R.7
  • 40
    • 0029131650 scopus 로고
    • In vitro modulation of rat adipocyte ghost membrane fluidity by cholesterol oxysterols
    • Lau W.F., and Das N.P. In vitro modulation of rat adipocyte ghost membrane fluidity by cholesterol oxysterols. Experientia 51 (1995) 731-737
    • (1995) Experientia , vol.51 , pp. 731-737
    • Lau, W.F.1    Das, N.P.2
  • 41
    • 0033681141 scopus 로고    scopus 로고
    • Presynaptic calcium stores underlie large-amplitude miniature IPSCs and spontaneous calcium transients
    • Llano I., Gonzalez J., Caputo C., Lai F.A., Blayney L.M., Tan Y.P., and Marty A. Presynaptic calcium stores underlie large-amplitude miniature IPSCs and spontaneous calcium transients. Nat Neurosci 3 (2000) 1256-1265
    • (2000) Nat Neurosci , vol.3 , pp. 1256-1265
    • Llano, I.1    Gonzalez, J.2    Caputo, C.3    Lai, F.A.4    Blayney, L.M.5    Tan, Y.P.6    Marty, A.7
  • 42
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo E.H., Dalkara T., and Moskowitz M.A. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 4 (2003) 399-415
    • (2003) Nat Rev Neurosci , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 44
    • 0347993182 scopus 로고    scopus 로고
    • Ectopic release of synaptic vesicles
    • Matsui K., and Jahr C.E. Ectopic release of synaptic vesicles. Neuron 40 (2003) 1173-1183
    • (2003) Neuron , vol.40 , pp. 1173-1183
    • Matsui, K.1    Jahr, C.E.2
  • 45
    • 33846020920 scopus 로고    scopus 로고
    • Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release
    • Maximov A., Shin O.H., Liu X., and Sudhof T.C. Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release. J Cell Biol 176 (2007) 113-124
    • (2007) J Cell Biol , vol.176 , pp. 113-124
    • Maximov, A.1    Shin, O.H.2    Liu, X.3    Sudhof, T.C.4
  • 46
    • 0033366383 scopus 로고    scopus 로고
    • Miniature synaptic events maintain dendritic spines via AMPA receptor activation
    • McKinney R.A., Capogna M., Durr R., Gahwiler B.H., and Thompson S.M. Miniature synaptic events maintain dendritic spines via AMPA receptor activation. Nat Neurosci 2 (1999) 44-49
    • (1999) Nat Neurosci , vol.2 , pp. 44-49
    • McKinney, R.A.1    Capogna, M.2    Durr, R.3    Gahwiler, B.H.4    Thompson, S.M.5
  • 47
    • 0034631955 scopus 로고    scopus 로고
    • Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors
    • McNew J.A., Weber T., Parlati F., Johnston R.J., Melia T.J., Sollner T.H., and Rothman J.E. Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. J Cell Biol 150 (2000) 105-117
    • (2000) J Cell Biol , vol.150 , pp. 105-117
    • McNew, J.A.1    Weber, T.2    Parlati, F.3    Johnston, R.J.4    Melia, T.J.5    Sollner, T.H.6    Rothman, J.E.7
  • 49
    • 0033361973 scopus 로고    scopus 로고
    • Reversal of synaptic vesicle docking at central synapses
    • Murthy V.N., and Stevens C.F. Reversal of synaptic vesicle docking at central synapses. Nat Neurosci 2 (1999) 503-507
    • (1999) Nat Neurosci , vol.2 , pp. 503-507
    • Murthy, V.N.1    Stevens, C.F.2
  • 50
    • 0034474467 scopus 로고    scopus 로고
    • SNAP-24, a Drosophila SNAP-25 homologue on granule membranes, is a putative mediator of secretion and granule-granule fusion in salivary glands
    • Niemeyer B.A., and Schwarz T.L. SNAP-24, a Drosophila SNAP-25 homologue on granule membranes, is a putative mediator of secretion and granule-granule fusion in salivary glands. J Cell Sci 113 Pt 22 (2000) 4055-4064
    • (2000) J Cell Sci , vol.113 , Issue.PART 22 , pp. 4055-4064
    • Niemeyer, B.A.1    Schwarz, T.L.2
  • 51
    • 0035898777 scopus 로고    scopus 로고
    • Calcium-dependent neurotransmitter release: synaptotagmin to the rescue
    • Nishiki T.I., and Augustine G.J. Calcium-dependent neurotransmitter release: synaptotagmin to the rescue. J Comp Neurol 436 (2001) 1-3
    • (2001) J Comp Neurol , vol.436 , pp. 1-3
    • Nishiki, T.I.1    Augustine, G.J.2
  • 52
    • 0035876476 scopus 로고    scopus 로고
    • Glutamate release and neuronal damage in ischemia
    • Nishizawa Y. Glutamate release and neuronal damage in ischemia. Life Sci 69 (2001) 369-381
    • (2001) Life Sci , vol.69 , pp. 369-381
    • Nishizawa, Y.1
  • 53
    • 0031975266 scopus 로고    scopus 로고
    • Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants
    • Nonet M.L., Saifee O., Zhao H., Rand J.B., and Wei L. Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants. J Neurosci 18 (1998) 70-80
    • (1998) J Neurosci , vol.18 , pp. 70-80
    • Nonet, M.L.1    Saifee, O.2    Zhao, H.3    Rand, J.B.4    Wei, L.5
  • 54
    • 1542569612 scopus 로고    scopus 로고
    • Miniature transmitter release: accident of nature or careful design?
    • Otsu Y., and Murphy T.H. Miniature transmitter release: accident of nature or careful design?. Sci STKE 211 (2003) pe54
    • (2003) Sci STKE , vol.211
    • Otsu, Y.1    Murphy, T.H.2
  • 55
    • 1642499166 scopus 로고    scopus 로고
    • Competition between phasic and asynchronous release for recovered synaptic vesicles at developing hippocampal autaptic synapses
    • Otsu Y., Shahrezaei V., Li B., Raymond L.A., Delaney K.R., and Murphy T.H. Competition between phasic and asynchronous release for recovered synaptic vesicles at developing hippocampal autaptic synapses. J Neurosci 24 (2004) 420-433
    • (2004) J Neurosci , vol.24 , pp. 420-433
    • Otsu, Y.1    Shahrezaei, V.2    Li, B.3    Raymond, L.A.4    Delaney, K.R.5    Murphy, T.H.6
  • 57
    • 0033179082 scopus 로고    scopus 로고
    • Correlation of miniature synaptic activity and evoked release probability in cultures of cortical neurons
    • Prange O., and Murphy T.H. Correlation of miniature synaptic activity and evoked release probability in cultures of cortical neurons. J Neurosci 19 (1999) 6427-6438
    • (1999) J Neurosci , vol.19 , pp. 6427-6438
    • Prange, O.1    Murphy, T.H.2
  • 59
    • 0036673069 scopus 로고    scopus 로고
    • Snares and Munc18 in synaptic vesicle fusion
    • Rizo J., and Sudhof T.C. Snares and Munc18 in synaptic vesicle fusion. Nat Rev Neurosci 3 (2002) 641-653
    • (2002) Nat Rev Neurosci , vol.3 , pp. 641-653
    • Rizo, J.1    Sudhof, T.C.2
  • 60
    • 0032931988 scopus 로고    scopus 로고
    • Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
    • Rodal S.K., Skretting G., Garred O., Vilhardt F., van Deurs B., and Sandvig K. Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol Biol Cell 10 (1999) 961-974
    • (1999) Mol Biol Cell , vol.10 , pp. 961-974
    • Rodal, S.K.1    Skretting, G.2    Garred, O.3    Vilhardt, F.4    van Deurs, B.5    Sandvig, K.6
  • 61
    • 0030175394 scopus 로고    scopus 로고
    • Definition of the readily releasable pool of vesicles at hippocampal synapses
    • Rosenmund C., and Stevens C.F. Definition of the readily releasable pool of vesicles at hippocampal synapses. Neuron 16 (1996) 1197-1207
    • (1996) Neuron , vol.16 , pp. 1197-1207
    • Rosenmund, C.1    Stevens, C.F.2
  • 62
    • 0030856448 scopus 로고    scopus 로고
    • Optical detection of a quantal presynaptic membrane turnover
    • Ryan T.A., Reuter H., and Smith S.J. Optical detection of a quantal presynaptic membrane turnover. Nature 388 (1997) 478-482
    • (1997) Nature , vol.388 , pp. 478-482
    • Ryan, T.A.1    Reuter, H.2    Smith, S.J.3
  • 63
    • 0031869652 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin
    • Saifee O., Wei L., and Nonet M.L. The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin. Mol Biol Cell 9 (1998) 1235-1252
    • (1998) Mol Biol Cell , vol.9 , pp. 1235-1252
    • Saifee, O.1    Wei, L.2    Nonet, M.L.3
  • 64
    • 22244474919 scopus 로고    scopus 로고
    • Distinct kinetic changes in neurotransmitter release after SNARE protein cleavage
    • Sakaba T., Stein A., Jahn R., and Neher E. Distinct kinetic changes in neurotransmitter release after SNARE protein cleavage. Science 309 (2005) 491-494
    • (2005) Science , vol.309 , pp. 491-494
    • Sakaba, T.1    Stein, A.2    Jahn, R.3    Neher, E.4
  • 65
    • 1842484428 scopus 로고    scopus 로고
    • Lipid rafts and the regulation of exocytosis
    • Salaun C., James D.J., and Chamberlain L.H. Lipid rafts and the regulation of exocytosis. Traffic 5 (2004) 255-264
    • (2004) Traffic , vol.5 , pp. 255-264
    • Salaun, C.1    James, D.J.2    Chamberlain, L.H.3
  • 66
    • 13844266201 scopus 로고    scopus 로고
    • An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission
    • Sara Y., Virmani T., Deak F., Liu X., and Kavalali E.T. An isolated pool of vesicles recycles at rest and drives spontaneous neurotransmission. Neuron 45 (2005) 563-573
    • (2005) Neuron , vol.45 , pp. 563-573
    • Sara, Y.1    Virmani, T.2    Deak, F.3    Liu, X.4    Kavalali, E.T.5
  • 67
    • 33644506134 scopus 로고    scopus 로고
    • Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse
    • Saviane C., and Silver R.A. Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse. Nature 439 (2006) 983-987
    • (2006) Nature , vol.439 , pp. 983-987
    • Saviane, C.1    Silver, R.A.2
  • 68
  • 69
    • 0035095914 scopus 로고    scopus 로고
    • Morphological correlates of functionally defined synaptic vesicle populations
    • Schikorski T., and Stevens C.F. Morphological correlates of functionally defined synaptic vesicle populations. Nat Neurosci 4 (2001) 391-395
    • (2001) Nat Neurosci , vol.4 , pp. 391-395
    • Schikorski, T.1    Stevens, C.F.2
  • 70
    • 0033152473 scopus 로고    scopus 로고
    • Released fraction and total size of a pool of immediately available transmitter quanta at a calyx synapse
    • Schneggenburger R., Meyer A.C., and Neher E. Released fraction and total size of a pool of immediately available transmitter quanta at a calyx synapse. Neuron 23 (1999) 399-409
    • (1999) Neuron , vol.23 , pp. 399-409
    • Schneggenburger, R.1    Meyer, A.C.2    Neher, E.3
  • 72
    • 0028817584 scopus 로고
    • Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission
    • Schulze K.L., Broadie K., Perin M.S., and Bellen H.J. Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell 80 (1995) 311-320
    • (1995) Cell , vol.80 , pp. 311-320
    • Schulze, K.L.1    Broadie, K.2    Perin, M.S.3    Bellen, H.J.4
  • 74
    • 0038107577 scopus 로고    scopus 로고
    • Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23
    • Sorensen J.B., Nagy G., Varoqueaux F., Nehring R.B., Brose N., Wilson M.C., and Neher E. Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell 114 (2003) 75-86
    • (2003) Cell , vol.114 , pp. 75-86
    • Sorensen, J.B.1    Nagy, G.2    Varoqueaux, F.3    Nehring, R.B.4    Brose, N.5    Wilson, M.C.6    Neher, E.7
  • 76
    • 0020533584 scopus 로고
    • Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat
    • Spady D.K., and Dietschy J.M. Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat. J Lipid Res 24 (1983) 303-315
    • (1983) J Lipid Res , vol.24 , pp. 303-315
    • Spady, D.K.1    Dietschy, J.M.2
  • 78
    • 0033637985 scopus 로고    scopus 로고
    • The synaptic vesicle cycle revisited
    • Sudhof T.C. The synaptic vesicle cycle revisited. Neuron 28 (2000) 317-320
    • (2000) Neuron , vol.28 , pp. 317-320
    • Sudhof, T.C.1
  • 79
    • 0037198628 scopus 로고    scopus 로고
    • Single and multiple vesicle fusion induce different rates of endocytosis at a central synapse
    • Sun J.Y., Wu X.S., and Wu L.G. Single and multiple vesicle fusion induce different rates of endocytosis at a central synapse. Nature 417 (2002) 555-559
    • (2002) Nature , vol.417 , pp. 555-559
    • Sun, J.Y.1    Wu, X.S.2    Wu, L.G.3
  • 81
    • 34547683444 scopus 로고    scopus 로고
    • Postsynaptic decoding of neural activity: eEF2 as a biochemical sensor coupling miniature synaptic transmission to local protein synthesis
    • Sutton M.A., Taylor A.M., Ito H.T., Pham A., and Schuman E.M. Postsynaptic decoding of neural activity: eEF2 as a biochemical sensor coupling miniature synaptic transmission to local protein synthesis. Neuron 55 (2007) 648-661
    • (2007) Neuron , vol.55 , pp. 648-661
    • Sutton, M.A.1    Taylor, A.M.2    Ito, H.T.3    Pham, A.4    Schuman, E.M.5
  • 82
    • 3042521496 scopus 로고    scopus 로고
    • Regulation of dendritic protein synthesis by miniature synaptic events
    • Sutton M.A., Wall N.R., Aakalu G.N., and Schuman E.M. Regulation of dendritic protein synthesis by miniature synaptic events. Science 304 (2004) 1979-1983
    • (2004) Science , vol.304 , pp. 1979-1983
    • Sutton, M.A.1    Wall, N.R.2    Aakalu, G.N.3    Schuman, E.M.4
  • 83
    • 33646504383 scopus 로고    scopus 로고
    • Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis
    • Sutton M.A., Ito H.T., Cressy P., Kempf C., Woo J.C., and Schuman E.M. Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis. Cell 125 (2006) 785-799
    • (2006) Cell , vol.125 , pp. 785-799
    • Sutton, M.A.1    Ito, H.T.2    Cressy, P.3    Kempf, C.4    Woo, J.C.5    Schuman, E.M.6
  • 84
    • 3543096759 scopus 로고    scopus 로고
    • Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
    • Sutton R.B., Fasshauer D., Jahn R., and Brunger A.T. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature 395 (1998) 347-353
    • (1998) Nature , vol.395 , pp. 347-353
    • Sutton, R.B.1    Fasshauer, D.2    Jahn, R.3    Brunger, A.T.4
  • 86
    • 33748605056 scopus 로고    scopus 로고
    • A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis
    • Tang J., Maximov A., Shin O.H., Dai H., Rizo J., and Sudhof T.C. A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis. Cell 126 (2006) 1175-1187
    • (2006) Cell , vol.126 , pp. 1175-1187
    • Tang, J.1    Maximov, A.2    Shin, O.H.3    Dai, H.4    Rizo, J.5    Sudhof, T.C.6
  • 87
    • 0031832632 scopus 로고    scopus 로고
    • Preferential utilization of newly synthesized cholesterol for brain growth in neonatal lambs
    • Turley S.D., Burns D.K., and Dietschy J.M. Preferential utilization of newly synthesized cholesterol for brain growth in neonatal lambs. Am J Physiol 274 (1998) E1099-E1105
    • (1998) Am J Physiol , vol.274
    • Turley, S.D.1    Burns, D.K.2    Dietschy, J.M.3
  • 88
  • 89
    • 0742323527 scopus 로고    scopus 로고
    • Homeostatic plasticity in the developing nervous system
    • Turrigiano G.G., and Nelson S.B. Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci 5 (2004) 97-107
    • (2004) Nat Rev Neurosci , vol.5 , pp. 97-107
    • Turrigiano, G.G.1    Nelson, S.B.2
  • 90
    • 0029858487 scopus 로고    scopus 로고
    • Localizing quantal currents along frog neuromuscular junctions
    • Van der Kloot W., and Naves L.A. Localizing quantal currents along frog neuromuscular junctions. J Physiol 497 (1996) 189-198
    • (1996) J Physiol , vol.497 , pp. 189-198
    • Van der Kloot, W.1    Naves, L.A.2
  • 91
    • 34247511202 scopus 로고    scopus 로고
    • Subnanometer fusion pores in spontaneous exocytosis of peptidergic vesicles
    • Vardjan N., Stenovec M., Jorgacevski J., Kreft M., and Zorec R. Subnanometer fusion pores in spontaneous exocytosis of peptidergic vesicles. J Neurosci 27 (2007) 4737-4746
    • (2007) J Neurosci , vol.27 , pp. 4737-4746
    • Vardjan, N.1    Stenovec, M.2    Jorgacevski, J.3    Kreft, M.4    Zorec, R.5
  • 92
    • 0037172972 scopus 로고    scopus 로고
    • Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
    • Varoqueaux F., Sigler A., Rhee J.S., Brose N., Enk C., Reim K., and Rosenmund C. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc Natl Acad Sci U S A 99 (2002) 9037-9042
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9037-9042
    • Varoqueaux, F.1    Sigler, A.2    Rhee, J.S.3    Brose, N.4    Enk, C.5    Reim, K.6    Rosenmund, C.7
  • 94
    • 0036742535 scopus 로고    scopus 로고
    • A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission
    • Vilinsky I., Stewart B.A., Drummond J., Robinson I., and Deitcher D.L. A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission. Genetics 162 (2002) 259-271
    • (2002) Genetics , vol.162 , pp. 259-271
    • Vilinsky, I.1    Stewart, B.A.2    Drummond, J.3    Robinson, I.4    Deitcher, D.L.5
  • 96
    • 33847616010 scopus 로고    scopus 로고
    • Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling
    • Wasser C.R., Ertunc M., Liu X., and Kavalali E.T. Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling. J Physiol 579 (2007) 413-429
    • (2007) J Physiol , vol.579 , pp. 413-429
    • Wasser, C.R.1    Ertunc, M.2    Liu, X.3    Kavalali, E.T.4
  • 98
    • 15244340674 scopus 로고    scopus 로고
    • Postsynaptic expression of homeostatic plasticity at neocortical synapses
    • Wierenga C.J., Ibata K., and Turrigiano G.G. Postsynaptic expression of homeostatic plasticity at neocortical synapses. J Neurosci 25 (2005) 2895-2905
    • (2005) J Neurosci , vol.25 , pp. 2895-2905
    • Wierenga, C.J.1    Ibata, K.2    Turrigiano, G.G.3
  • 99
    • 0033180609 scopus 로고    scopus 로고
    • The reduced release probability of releasable vesicles during recovery from short-term synaptic depression
    • Wu L.G., and Borst J.G. The reduced release probability of releasable vesicles during recovery from short-term synaptic depression. Neuron 23 (1999) 821-832
    • (1999) Neuron , vol.23 , pp. 821-832
    • Wu, L.G.1    Borst, J.G.2
  • 100
    • 0037598589 scopus 로고    scopus 로고
    • Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release
    • Wucherpfennig T., Wilsch-Brauninger M., and Gonzalez-Gaitan M. Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol 161 (2003) 609-624
    • (2003) J Cell Biol , vol.161 , pp. 609-624
    • Wucherpfennig, T.1    Wilsch-Brauninger, M.2    Gonzalez-Gaitan, M.3
  • 101
    • 0033598965 scopus 로고    scopus 로고
    • Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis
    • Xu T., Rammner B., Margittai M., Artalejo A.R., Neher E., and Jahn R. Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis. Cell 99 (1999) 713-722
    • (1999) Cell , vol.99 , pp. 713-722
    • Xu, T.1    Rammner, B.2    Margittai, M.3    Artalejo, A.R.4    Neher, E.5    Jahn, R.6
  • 102
    • 0037027739 scopus 로고    scopus 로고
    • Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release
    • Yoshihara M., and Littleton J.T. Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release. Neuron 36 (2002) 897-908
    • (2002) Neuron , vol.36 , pp. 897-908
    • Yoshihara, M.1    Littleton, J.T.2
  • 104
    • 14044252895 scopus 로고    scopus 로고
    • Proteolysis of SNARE proteins alters facilitation and depression in a specific way
    • Young Jr. S.M. Proteolysis of SNARE proteins alters facilitation and depression in a specific way. Proc Natl Acad Sci U S A 102 (2005) 2614-2619
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2614-2619
    • Young Jr., S.M.1
  • 105
    • 33645891984 scopus 로고    scopus 로고
    • Cholesterol and synaptic transmitter release at crayfish neuromuscular junctions
    • Zamir O., and Charlton M.P. Cholesterol and synaptic transmitter release at crayfish neuromuscular junctions. J Physiol 571 (2006) 83-99
    • (2006) J Physiol , vol.571 , pp. 83-99
    • Zamir, O.1    Charlton, M.P.2
  • 107
    • 0034710691 scopus 로고    scopus 로고
    • Transport, capture and exocytosis of single synaptic vesicles at active zones
    • Zenisek D., Steyer J.A., and Almers W. Transport, capture and exocytosis of single synaptic vesicles at active zones. Nature 406 (2000) 849-854
    • (2000) Nature , vol.406 , pp. 849-854
    • Zenisek, D.1    Steyer, J.A.2    Almers, W.3
  • 108
    • 13844294451 scopus 로고    scopus 로고
    • Minis: whence and wherefore?
    • Zucker R.S. Minis: whence and wherefore?. Neuron 45 (2005) 482-484
    • (2005) Neuron , vol.45 , pp. 482-484
    • Zucker, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.