메뉴 건너뛰기




Volumn 102, Issue 11, 2008, Pages 1495-1501

Efficacy and Safety of Ezetimibe Added on to Atorvastatin (40 mg) Compared With Uptitration of Atorvastatin (to 80 mg) in Hypercholesterolemic Patients at High Risk of Coronary Heart Disease

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; ASPARTATE AMINOTRANSFERASE; ATORVASTATIN; CREATINE KINASE; EZETIMIBE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 58149472552     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2008.09.076     Document Type: Article
Times cited : (82)

References (28)
  • 1
    • 0034723758 scopus 로고    scopus 로고
    • The Lipid Treatment Assessment Project (L-TAP): a multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals
    • Pearson T.A., Laurora I., Chu H., and Kafonek S. The Lipid Treatment Assessment Project (L-TAP): a multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals. Arch Intern Med 160 (2000) 459-467
    • (2000) Arch Intern Med , vol.160 , pp. 459-467
    • Pearson, T.A.1    Laurora, I.2    Chu, H.3    Kafonek, S.4
  • 3
    • 23644457791 scopus 로고    scopus 로고
    • Results of the National Cholesterol Education (NCEP) Program Evaluation ProjecT Utilizing Novel E-Technology (NEPTUNE) II survey and implications for treatment under the recent NCEP Writing Group recommendations
    • Davidson M.H., Maki K.C., Pearson T.A., Pasternak R.C., Deedwania P.C., McKenney J.M., Fonarow G.C., Maron D.J., Ansell B.J., Clark L.T., and Ballantyne C.M. Results of the National Cholesterol Education (NCEP) Program Evaluation ProjecT Utilizing Novel E-Technology (NEPTUNE) II survey and implications for treatment under the recent NCEP Writing Group recommendations. Am J Cardiol 96 (2005) 556-563
    • (2005) Am J Cardiol , vol.96 , pp. 556-563
    • Davidson, M.H.1    Maki, K.C.2    Pearson, T.A.3    Pasternak, R.C.4    Deedwania, P.C.5    McKenney, J.M.6    Fonarow, G.C.7    Maron, D.J.8    Ansell, B.J.9    Clark, L.T.10    Ballantyne, C.M.11
  • 6
    • 58149460998 scopus 로고    scopus 로고
    • Merck & Co. Inc., Merck & Co. Inc, Whitehouse Station, NJ
    • Merck & Co. Inc. Zocor (simvastatin) tablets [package insert] (2007), Merck & Co. Inc, Whitehouse Station, NJ
    • (2007) Zocor (simvastatin) tablets [package insert]
  • 7
    • 0038645309 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)
    • Jones P.H., Davidson M.H., Stein E.A., Bays H.E., McKenney J.M., Miller E., Cain V.A., and Blasetto J.W. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). Am J Cardiol 92 (2003) 152-160
    • (2003) Am J Cardiol , vol.92 , pp. 152-160
    • Jones, P.H.1    Davidson, M.H.2    Stein, E.A.3    Bays, H.E.4    McKenney, J.M.5    Miller, E.6    Cain, V.A.7    Blasetto, J.W.8
  • 10
    • 0037111924 scopus 로고    scopus 로고
    • Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia
    • Dujovne C.A., Ettinger M.P., McNeer J.F., Lipka L.J., LeBeaut A.P., Suresh R., Yang B., and Veltri E.P. Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia. Am J Cardiol 90 (2002) 1092-1097
    • (2002) Am J Cardiol , vol.90 , pp. 1092-1097
    • Dujovne, C.A.1    Ettinger, M.P.2    McNeer, J.F.3    Lipka, L.J.4    LeBeaut, A.P.5    Suresh, R.6    Yang, B.7    Veltri, E.P.8
  • 12
    • 23244465200 scopus 로고    scopus 로고
    • New insights into the genetic regulation of intestinal cholesterol absorption
    • Lammert F., and Wang D.Q. New insights into the genetic regulation of intestinal cholesterol absorption. Gastroenterology 129 (2005) 718-734
    • (2005) Gastroenterology , vol.129 , pp. 718-734
    • Lammert, F.1    Wang, D.Q.2
  • 13
    • 0037111890 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia
    • Gagne C., Bays H.E., Weiss S.R., Mata P., Quinto K., Melino M., Cho M., Musliner T.A., and Gumbiner B. Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia. Am J Cardiol 90 (2002) 1084-1091
    • (2002) Am J Cardiol , vol.90 , pp. 1084-1091
    • Gagne, C.1    Bays, H.E.2    Weiss, S.R.3    Mata, P.4    Quinto, K.5    Melino, M.6    Cho, M.7    Musliner, T.A.8    Gumbiner, B.9
  • 15
    • 0037504445 scopus 로고    scopus 로고
    • Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial
    • Ballantyne C.M., Houri J., Notarbartolo A., Melani L., Lipka L.J., Suresh R., Sun S., LeBeaut A.P., Sager P.T., and Veltri E.P. Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Circulation 107 (2003) 2409-2415
    • (2003) Circulation , vol.107 , pp. 2409-2415
    • Ballantyne, C.M.1    Houri, J.2    Notarbartolo, A.3    Melani, L.4    Lipka, L.J.5    Suresh, R.6    Sun, S.7    LeBeaut, A.P.8    Sager, P.T.9    Veltri, E.P.10
  • 16
    • 2342574933 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial
    • Goldberg A.C., Sapre A., Liu J., Capece R., and Mitchel Y.B. Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial. Mayo Clin Proc 79 (2004) 620-629
    • (2004) Mayo Clin Proc , vol.79 , pp. 620-629
    • Goldberg, A.C.1    Sapre, A.2    Liu, J.3    Capece, R.4    Mitchel, Y.B.5
  • 17
    • 2942574385 scopus 로고    scopus 로고
    • Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals
    • Feldman T., Koren M., Insull Jr. W., McKenney J., Schrott H., Lewin A., Shah S., Sidisin M., Cho M., Kush D., and Mitchel Y. Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals. Am J Cardiol 93 (2004) 1481-1486
    • (2004) Am J Cardiol , vol.93 , pp. 1481-1486
    • Feldman, T.1    Koren, M.2    Insull Jr., W.3    McKenney, J.4    Schrott, H.5    Lewin, A.6    Shah, S.7    Sidisin, M.8    Cho, M.9    Kush, D.10    Mitchel, Y.11
  • 18
    • 18244390229 scopus 로고    scopus 로고
    • A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the Ezetimibe Add-on to Statin for Effectiveness (EASE) trial
    • Pearson T.A., Denke M.A., McBride P.E., Battisti W.P., Brady W.E., and Palmisano J. A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the Ezetimibe Add-on to Statin for Effectiveness (EASE) trial. Mayo Clin Proc 80 (2005) 587-595
    • (2005) Mayo Clin Proc , vol.80 , pp. 587-595
    • Pearson, T.A.1    Denke, M.A.2    McBride, P.E.3    Battisti, W.P.4    Brady, W.E.5    Palmisano, J.6
  • 19
    • 16244402675 scopus 로고    scopus 로고
    • Long-term safety and tolerability profiles and lipid-modifying efficacy of ezetimibe coadministered with ongoing simvastatin treatment: a multicenter, randomized, double-blind, placebo-controlled, 48-week extension study
    • Masana L., Mata P., Gagne C., Sirah W., Cho M., Johnson-Levonas A.O., Meehan A., Troxell J.K., and Gumbiner B. Long-term safety and tolerability profiles and lipid-modifying efficacy of ezetimibe coadministered with ongoing simvastatin treatment: a multicenter, randomized, double-blind, placebo-controlled, 48-week extension study. Clin Ther 27 (2005) 174-184
    • (2005) Clin Ther , vol.27 , pp. 174-184
    • Masana, L.1    Mata, P.2    Gagne, C.3    Sirah, W.4    Cho, M.5    Johnson-Levonas, A.O.6    Meehan, A.7    Troxell, J.K.8    Gumbiner, B.9
  • 20
    • 4544250506 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia
    • Davidson M.H., Ballantyne C.M., Kerzner B., Melani L., Sager P.T., Lipka L., Strony J., Suresh R., and Veltri E. Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia. Int J Clin Pract 58 (2004) 746-755
    • (2004) Int J Clin Pract , vol.58 , pp. 746-755
    • Davidson, M.H.1    Ballantyne, C.M.2    Kerzner, B.3    Melani, L.4    Sager, P.T.5    Lipka, L.6    Strony, J.7    Suresh, R.8    Veltri, E.9
  • 21
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285 (2001) 2486-2497
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 23
    • 0003244085 scopus 로고    scopus 로고
    • Longitudinal data analysis of continuous and discrete responses for pre-post designs
    • Liang K.Y., and Zeger S.L. Longitudinal data analysis of continuous and discrete responses for pre-post designs. Sankya Series B 62 (2000) 134-148
    • (2000) Sankya Series B , vol.62 , pp. 134-148
    • Liang, K.Y.1    Zeger, S.L.2
  • 24
    • 0021832508 scopus 로고
    • Comparative analysis of two rates
    • Miettinen O., and Nurminen M. Comparative analysis of two rates. Stat Med 4 (1985) 213-226
    • (1985) Stat Med , vol.4 , pp. 213-226
    • Miettinen, O.1    Nurminen, M.2
  • 25
    • 4644256971 scopus 로고    scopus 로고
    • Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin
    • Stein E., Stender S., Mata P., Sager P., Ponsonnet D., Melani L., Lipka L., Suresh R., Maccubbin D., and Veltri E. Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin. Am Heart J 148 (2004) 447-455
    • (2004) Am Heart J , vol.148 , pp. 447-455
    • Stein, E.1    Stender, S.2    Mata, P.3    Sager, P.4    Ponsonnet, D.5    Melani, L.6    Lipka, L.7    Suresh, R.8    Maccubbin, D.9    Veltri, E.10
  • 26
    • 58149456534 scopus 로고    scopus 로고
    • Merck/Schering-Plough Pharmaceuticals, Merck/Schering-Plough Pharmaceuticals, North Wales, PA
    • Merck/Schering-Plough Pharmaceuticals. Zetia (ezetimibe) [package insert] (2008), Merck/Schering-Plough Pharmaceuticals, North Wales, PA
    • (2008) Zetia (ezetimibe) [package insert]
  • 27
    • 0344490262 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial
    • Melani L., Mills R., Hassman D., Lipetz R., Lipka L., LeBeaut A., Suresh R., Mukhopadhyay P., and Veltri E. Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Eur Heart J 24 (2003) 717-728
    • (2003) Eur Heart J , vol.24 , pp. 717-728
    • Melani, L.1    Mills, R.2    Hassman, D.3    Lipetz, R.4    Lipka, L.5    LeBeaut, A.6    Suresh, R.7    Mukhopadhyay, P.8    Veltri, E.9
  • 28
    • 33751229269 scopus 로고    scopus 로고
    • Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study-the Ezetrol Add-On Study
    • Bissonnette S., Habib R., Sampalis F., Boukas S., and Sampalis J.S. Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study-the Ezetrol Add-On Study. Can J Cardiol 22 (2006) 1035-1044
    • (2006) Can J Cardiol , vol.22 , pp. 1035-1044
    • Bissonnette, S.1    Habib, R.2    Sampalis, F.3    Boukas, S.4    Sampalis, J.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.