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Guarantor of the article: Uri Ladabaum, M.D., M.S. Specific author contributions: Eugene Yen and Uri Ladabaum: conception and design of the study, analysis and interpretation of the data, and drafting and critical revision of the manuscript. Sunanda Kane: conception and design of the study and critical revision of the manuscript. Financial support: The support for this study was, in part, provided by an unrestricted research grant from Procter & Gamble Pharmaceuticals, Cincinnati, Ohio. Potential competing interests: Dr. Yen in on the Speaker's Bureau of Procter & Gamble. Dr. Kane is on the Speaker's Bureau of Procter & Gamble, Salix, and Shire, is a consultant for Procter & Gamble and Shir, and has received research support from Procter & Gamble. The other authors have no potential conflicts of interest relating to this work.
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