메뉴 건너뛰기




Volumn 4, Issue 6, 2008, Pages 329-340

In vivo biomarkers for targeting colorectal neoplasms

Author keywords

Adenocarcinoma; Biomarker; Colon; Endoscopy; Molecular imaging; Targeted

Indexed keywords

ANTINEOPLASTIC AGENT; APC PROTEIN; BEVACIZUMAB; CATHEPSIN B; CETUXIMAB; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PANITUMUMAB; TRANSCRIPTION FACTOR CDX2; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR;

EID: 58149385605     PISSN: 15740153     EISSN: None     Source Type: Journal    
DOI: 10.3233/cbm-2008-4605     Document Type: Article
Times cited : (5)

References (68)
  • 1
    • 46049104223 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta: American Cancer Society;
    • American Cancer Society. Cancer Facts & Figures 2008. Atlanta: American Cancer Society; 2008.
    • (2008) Cancer Facts & Figures 2008
  • 2
    • 33749601690 scopus 로고    scopus 로고
    • How much can current interventions reduce colorectal cancer mortality in the US Mortality projections for scenarios of risk-factor modification, screening, and treatment
    • I. Vogelaar, M. van Ballegooijen, D. Schrag et al., How much can current interventions reduce colorectal cancer mortality in the US Mortality projections for scenarios of risk-factor modification, screening, and treatment, Cancer 107 (2006), 1624-1633.
    • (2006) Cancer , vol.107 , pp. 1624-1633
    • Vogelaar, I.1    van Ballegooijen, M.2    Schrag, D.3
  • 3
    • 5044234455 scopus 로고    scopus 로고
    • National Polyp Study Workgroup. Flat adenomas in the National Polyp Study: Is there increased risk for high-grade dysplasia initially or during surveillance?
    • M.J. O'brien, S.J. Winawer, A.G. Zauber et al., National Polyp Study Workgroup. Flat adenomas in the National Polyp Study: Is there increased risk for high-grade dysplasia initially or during surveillance? Clin Gastroenterol Hepatol 2 (2004), 905-911.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 905-911
    • O'brien, M.J.1    Winawer, S.J.2    Zauber, A.G.3
  • 5
    • 40449138243 scopus 로고    scopus 로고
    • Prevalence of non-polypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults
    • R.M. Soetikno, T. Kaltenbach, R.V. Rouse, W. Park, A. Maheshwari, T. Sato, S. Matsui and S. Friedl, Prevalence of non-polypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults, JAMA 299 (2008), 1027-1035.
    • (2008) JAMA , vol.299 , pp. 1027-1035
    • Soetikno, R.M.1    Kaltenbach, T.2    Rouse, R.V.3    Park, W.4    Maheshwari, A.5    Sato, T.6    Matsui, S.7    Friedl, S.8
  • 6
    • 0344616902 scopus 로고    scopus 로고
    • A prospective clinico-pathological and endoscopic evaluation of flat and depressed colorectal lesions in the United Kingdom
    • D.P. Hurlstone, S.S. Cross, I. Adam, A.J. Shorthouse, S. Brown, D.S. Sanders and A.J. Lobo, A prospective clinico-pathological and endoscopic evaluation of flat and depressed colorectal lesions in the United Kingdom, Am J Gastroenterol 98 (2003), 2543-2549.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2543-2549
    • Hurlstone, D.P.1    Cross, S.S.2    Adam, I.3    Shorthouse, A.J.4    Brown, S.5    Sanders, D.S.6    Lobo, A.J.7
  • 8
    • 0029781652 scopus 로고    scopus 로고
    • Small, flat colorectal neoplasias in long-standing ulcerative colitis detected by high-resolution electronic video endoscopy
    • E. Jaramillo, M. Watanabe, R. Befrits, E. Ponce de Leon, C. Rubio and P. Slezak, Small, flat colorectal neoplasias in long-standing ulcerative colitis detected by high-resolution electronic video endoscopy, Gastrointest Endosc 44 (1996), 15-22.
    • (1996) Gastrointest Endosc , vol.44 , pp. 15-22
    • Jaramillo, E.1    Watanabe, M.2    Befrits, R.3    Ponce de Leon, E.4    Rubio, C.5    Slezak, P.6
  • 12
    • 33748340821 scopus 로고    scopus 로고
    • Surgical adjuvant therapy for colorectal cancer: Current approaches and future directions
    • D.K. Monga and M.J. O'Connell, Surgical adjuvant therapy for colorectal cancer: Current approaches and future directions, Ann Surg Oncol 13 (2006), 1021-1034.
    • (2006) Ann Surg Oncol , vol.13 , pp. 1021-1034
    • Monga, D.K.1    O'Connell, M.J.2
  • 14
    • 0033858528 scopus 로고    scopus 로고
    • The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis
    • D.C. Chung, The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis, Gastroenterology 119 (2000), 854-865.
    • (2000) Gastroenterology , vol.119 , pp. 854-865
    • Chung, D.C.1
  • 15
    • 0026648941 scopus 로고
    • Genetic alterations in the adenoma-carcinoma sequence
    • K.R. Cho and B. Vogelstein, Genetic alterations in the adenoma-carcinoma sequence, Cancer 70(6S) (1992), 1727-1731.
    • (1992) Cancer , vol.70 , Issue.6 S , pp. 1727-1731
    • Cho, K.R.1    Vogelstein, B.2
  • 16
    • 33750536877 scopus 로고    scopus 로고
    • Distal colorectal cancers with microsatellite instability (MSI) display distinct gene expression profiles that are different from proximal MSI cancers
    • T. Watanabe, T. Kobunai, E. Toda et al., Distal colorectal cancers with microsatellite instability (MSI) display distinct gene expression profiles that are different from proximal MSI cancers, Cancer Res 66 (2006), 9804-9808.
    • (2006) Cancer Res , vol.66 , pp. 9804-9808
    • Watanabe, T.1    Kobunai, T.2    Toda, E.3
  • 17
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • C. Lengauer, K.W. Kinzler and B. Vogelstein, Genetic instability in colorectal cancers, Nature 386 (1997), 623-627.
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 19
    • 32944478445 scopus 로고    scopus 로고
    • Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer
    • E.J. Fox, D.T. Leahy, R. Geraghty, H.E. Mulcahy, D. Fennelly, J.M. Hyland, D.P. O'Donoghue and K. Sheahan, Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer, J Mol Diagn 8 (2006), 68-75.
    • (2006) J Mol Diagn , vol.8 , pp. 68-75
    • Fox, E.J.1    Leahy, D.T.2    Geraghty, R.3    Mulcahy, H.E.4    Fennelly, D.5    Hyland, J.M.6    O'Donoghue, D.P.7    Sheahan, K.8
  • 22
    • 26944483542 scopus 로고    scopus 로고
    • Colon cancer prognosis prediction by gene expression profiling
    • A. Barrier, A. Lemoine, P.Y. Boelle et al., Colon cancer prognosis prediction by gene expression profiling, Oncogene 24 (2005), 6155-6164.
    • (2005) Oncogene , vol.24 , pp. 6155-6164
    • Barrier, A.1    Lemoine, A.2    Boelle, P.Y.3
  • 23
    • 0026562404 scopus 로고
    • Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
    • L.K. Su, K.W. Kinzler, B. Vogelstein et al., Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene, Science 256 (1992), 668-670.
    • (1992) Science , vol.256 , pp. 668-670
    • Su, L.K.1    Kinzler, K.W.2    Vogelstein, B.3
  • 24
    • 0032900534 scopus 로고    scopus 로고
    • Mammalian MutS homologue 5 is required for chromosome pairing in meiosis
    • W. Edelmann, P.E. Cohen, B. Kneitz et al., Mammalian MutS homologue 5 is required for chromosome pairing in meiosis, Nat Genet 21 (1999), 123-127.
    • (1999) Nat Genet , vol.21 , pp. 123-127
    • Edelmann, W.1    Cohen, P.E.2    Kneitz, B.3
  • 25
    • 0037169361 scopus 로고    scopus 로고
    • Cancer modeling in the modern era: Progress and challenges
    • T. Van Dyke and T. Jacks, Cancer modeling in the modern era: Progress and challenges, Cell 108 (2002), 135-144.
    • (2002) Cell , vol.108 , pp. 135-144
    • Van Dyke, T.1    Jacks, T.2
  • 26
    • 0036549015 scopus 로고    scopus 로고
    • Conditional mouse models of sporadic cancer
    • J. Jonkers and A. Berns, Conditional mouse models of sporadic cancer, Nat Rev Cancer 2 (2002), 251-265.
    • (2002) Nat Rev Cancer , vol.2 , pp. 251-265
    • Jonkers, J.1    Berns, A.2
  • 28
    • 0032805892 scopus 로고    scopus 로고
    • Colitis in transgenic and knockout animals as models of human inflammatory bowel disease
    • A.K. Bhan, E. Mizoguchi, R.N. Smith and A. Mizoguchi, Colitis in transgenic and knockout animals as models of human inflammatory bowel disease. Immunol Rev 169 (1999), 195-207.
    • (1999) Immunol Rev , vol.169 , pp. 195-207
    • Bhan, A.K.1    Mizoguchi, E.2    Smith, R.N.3    Mizoguchi, A.4
  • 29
    • 0038064509 scopus 로고    scopus 로고
    • Molecular biomarkers of colorectal carcinogenesis and their role in surveillance and early intervention
    • G. Garcea, R.A. Sharma, A. Dennison, W.P. Steward, A. Gescher and D.P. Berry, Molecular biomarkers of colorectal carcinogenesis and their role in surveillance and early intervention, Eur J Cancer 39 (2003), 1041-1052.
    • (2003) Eur J Cancer , vol.39 , pp. 1041-1052
    • Garcea, G.1    Sharma, R.A.2    Dennison, A.3    Steward, W.P.4    Gescher, A.5    Berry, D.P.6
  • 30
    • 0033651576 scopus 로고    scopus 로고
    • Potential roles of genetic biomarkers in colorectal cancer chemoprevention
    • S. Syngal, G. Clarke and P. Bandipalliam, Potential roles of genetic biomarkers in colorectal cancer chemoprevention, J Cell Biochem Suppl 34 (2000), 28-34.
    • (2000) J Cell Biochem Suppl , vol.34 , pp. 28-34
    • Syngal, S.1    Clarke, G.2    Bandipalliam, P.3
  • 31
    • 30444436907 scopus 로고    scopus 로고
    • Gene expression profiling of nonneoplastic mucosa may predict clinical outcome of colon cancer patients
    • A. Barrier, P.Y. Boelle, A. Lemoine et al., Gene expression profiling of nonneoplastic mucosa may predict clinical outcome of colon cancer patients, Dis Colon Rectum 48 (2005), 2238-2248.
    • (2005) Dis Colon Rectum , vol.48 , pp. 2238-2248
    • Barrier, A.1    Boelle, P.Y.2    Lemoine, A.3
  • 32
    • 24144469347 scopus 로고    scopus 로고
    • Gene-expression profiling predicts recurrence in Dukes C colorectal cancer
    • D. Arango, P. Laiho, A. Kokko et al., Gene-expression profiling predicts recurrence in Dukes C colorectal cancer, Gastroenterology 129 (2005), 874-884.
    • (2005) Gastroenterology , vol.129 , pp. 874-884
    • Arango, D.1    Laiho, P.2    Kokko, A.3
  • 33
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Y. Takahashi, Y. Kitadai, C.D. Bucana, K.R. Cleary and L.M. Ellis, Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer, Cancer Res 55 (1995), 3964-398.
    • (1995) Cancer Res , vol.55 , pp. 3964-4398
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 34
    • 0031789314 scopus 로고    scopus 로고
    • Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
    • S.I. Ishigami, S. Arii, M. Furutani, M. Niwano, T. Harada, M. Mizumoto, A. Mori, H. Onodera and M. Imamura, Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer, Br J Cancer 78 (1998), 1379-1384.
    • (1998) Br J Cancer , vol.78 , pp. 1379-1384
    • Ishigami, S.I.1    Arii, S.2    Furutani, M.3    Niwano, M.4    Harada, T.5    Mizumoto, M.6    Mori, A.7    Onodera, H.8    Imamura, M.9
  • 35
    • 0034090366 scopus 로고    scopus 로고
    • Factors influencing tissue concentration of vascular endothelial growth factor in colorectal carcinoma
    • T. Ono and C. Miki, Factors influencing tissue concentration of vascular endothelial growth factor in colorectal carcinoma, Am J Gastroenterol 95 (2000), 1062-1067.
    • (2000) Am J Gastroenterol , vol.95 , pp. 1062-1067
    • Ono, T.1    Miki, C.2
  • 37
    • 34247849335 scopus 로고    scopus 로고
    • Target practice: Lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer
    • M. Los, J.M. Roodhart and E.E. Voest, Target practice: Lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer, Oncologist 12 (2007), 443-450.
    • (2007) Oncologist , vol.12 , pp. 443-450
    • Los, M.1    Roodhart, J.M.2    Voest, E.E.3
  • 38
    • 0023238874 scopus 로고
    • Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor
    • W.S. Chen, C.S. Lazar, M. Poenie, R.Y. Tsien, G.N. Gill and M.G. Rosenfeld, Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor, Nature 328 (1987), 820-823.
    • (1987) Nature , vol.328 , pp. 820-823
    • Chen, W.S.1    Lazar, C.S.2    Poenie, M.3    Tsien, R.Y.4    Gill, G.N.5    Rosenfeld, M.G.6
  • 39
    • 19944427228 scopus 로고    scopus 로고
    • Prognostic value of p27, p53, and vascular endothelial growth factor in Dukes A and B colon cancer patients undergoing potentially curative surgery
    • G. Galizia, F. Ferraraccio, E. Lieto et al., Prognostic value of p27, p53, and vascular endothelial growth factor in Dukes A and B colon cancer patients undergoing potentially curative surgery, Dis Colon Rectum 47 (2004), 1904-1914.
    • (2004) Dis Colon Rectum , vol.47 , pp. 1904-1914
    • Galizia, G.1    Ferraraccio, F.2    Lieto, E.3
  • 40
    • 2442480522 scopus 로고    scopus 로고
    • Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: A tissue microarray study
    • M.B. Resnick, J. Routhier, T. Konkin, E. Sabo and V.E. Pricolo, Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: A tissue microarray study, Clin Cancer Res 10 (2004), 3069-3075.
    • (2004) Clin Cancer Res , vol.10 , pp. 3069-3075
    • Resnick, M.B.1    Routhier, J.2    Konkin, T.3    Sabo, E.4    Pricolo, V.E.5
  • 42
    • 36148941301 scopus 로고    scopus 로고
    • Cetuximab for the treatment of colorectal cancer
    • D.J. Jonker, C.J. O'Callaghan, C.S. Karapetis et al., Cetuximab for the treatment of colorectal cancer, N Engl J Med 357 (2007), 2040-2048.
    • (2007) N Engl J Med , vol.357 , pp. 2040-2048
    • Jonker, D.J.1    O'Callaghan, C.J.2    Karapetis, C.S.3
  • 43
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • D. Cunningham, Y. Humblet, S. Siena et al., Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer, N Engl J Med 351 (2004), 337-345.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 44
    • 45349097237 scopus 로고    scopus 로고
    • Panitumumab: Human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer
    • M.Wu, A. Rivkin and T. Pham, Panitumumab: Human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer, Clin Ther 30 (2008), 14-30.
    • (2008) Clin Ther , vol.30 , pp. 14-30
    • Wu, M.1    Rivkin, A.2    Pham, T.3
  • 45
    • 0038051343 scopus 로고    scopus 로고
    • C.M. Frederiksen, S. Knudsen, S. Laurberg and T.F. Ørntoft, Classification of Dukes' B and C colorectal cancers using expression arrays, J Cancer Res Clin Oncol 129 (2003), 263-271.
    • C.M. Frederiksen, S. Knudsen, S. Laurberg and T.F. Ørntoft, Classification of Dukes' B and C colorectal cancers using expression arrays, J Cancer Res Clin Oncol 129 (2003), 263-271.
  • 47
    • 20644443287 scopus 로고    scopus 로고
    • Molecular staging for survival prediction of colorectal cancer patients
    • S. Eschrich, I. Yang, G. Bloom et al., Molecular staging for survival prediction of colorectal cancer patients, J Clin Oncol 23 (2005), 3526-3535.
    • (2005) J Clin Oncol , vol.23 , pp. 3526-3535
    • Eschrich, S.1    Yang, I.2    Bloom, G.3
  • 48
    • 33748706768 scopus 로고    scopus 로고
    • Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization
    • M.A. Funovics, H. Alencar, X. Montet, R. Weissleder and U. Mahmood, Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization, Gastrointest Endosc 64 (2006), 589-597.
    • (2006) Gastrointest Endosc , vol.64 , pp. 589-597
    • Funovics, M.A.1    Alencar, H.2    Montet, X.3    Weissleder, R.4    Mahmood, U.5
  • 49
    • 34250828565 scopus 로고    scopus 로고
    • Colonic adenocarcinomas: Near-infrared microcatheter imaging of smart probes for early detection-study in mice
    • H. Alencar, M.A. Funovics, J. Figueiredo, H. Sawaya, R. Weissleder and U. Mahmood, Colonic adenocarcinomas: Near-infrared microcatheter imaging of smart probes for early detection-study in mice, Radiology 244 (2007), 232-238.
    • (2007) Radiology , vol.244 , pp. 232-238
    • Alencar, H.1    Funovics, M.A.2    Figueiredo, J.3    Sawaya, H.4    Weissleder, R.5    Mahmood, U.6
  • 51
    • 25644437228 scopus 로고    scopus 로고
    • A novel videoendoscopy system by using autofluorescence and reflectance imaging for diagnosis of esophagogastric cancers
    • N. Uedo, H. Iishi, M. Tatsuta et al., A novel videoendoscopy system by using autofluorescence and reflectance imaging for diagnosis of esophagogastric cancers, Gastrointest Endosc 62 (2005), 521-528.
    • (2005) Gastrointest Endosc , vol.62 , pp. 521-528
    • Uedo, N.1    Iishi, H.2    Tatsuta, M.3
  • 52
    • 0032850907 scopus 로고    scopus 로고
    • The histological basis of detection of adenoma and cancer in the colon by autofluorescence endoscopic imaging
    • K. Izuishi, H. Tajiri, T. Fujii, N. Boku, A. Ohtsu, T. Ohnishi, M. Ryu, T. Kinoshita and S. Yoshida, The histological basis of detection of adenoma and cancer in the colon by autofluorescence endoscopic imaging, Endoscopy 31 (1999), 511-516.
    • (1999) Endoscopy , vol.31 , pp. 511-516
    • Izuishi, K.1    Tajiri, H.2    Fujii, T.3    Boku, N.4    Ohtsu, A.5    Ohnishi, T.6    Ryu, M.7    Kinoshita, T.8    Yoshida, S.9
  • 54
    • 84900264036 scopus 로고    scopus 로고
    • J.B. Pawley ed, 3rd ed, Springer Verlag, New York
    • J.B. Pawley ed., Handbook of Biological Confocal Microscopy, 3rd ed., Springer Verlag, New York (2006).
    • (2006) Handbook of Biological Confocal Microscopy
  • 55
    • 9144243915 scopus 로고    scopus 로고
    • Fibered confocal fluorescence microscopy (Cell-viZio) facilitates extended imaging in the field of microcirculation, A comparison with intravital microscopy
    • E. Laemmel, M. Genet, G. Le Goualher, A. Perchant, J.F. Le Gargasson and E. Vicaut, Fibered confocal fluorescence microscopy (Cell-viZio) facilitates extended imaging in the field of microcirculation, A comparison with intravital microscopy, J Vasc Res 41 (2004), 400-411.
    • (2004) J Vasc Res , vol.41 , pp. 400-411
    • Laemmel, E.1    Genet, M.2    Le Goualher, G.3    Perchant, A.4    Le Gargasson, J.F.5    Vicaut, E.6
  • 57
    • 0031749031 scopus 로고    scopus 로고
    • Radioimmunolocalization of primary and metastatic breast cancer
    • R.P. Baum and T.H. Brümmendorf, Radioimmunolocalization of primary and metastatic breast cancer, Q J Nucl Med 42 (1998), 33-42.
    • (1998) Q J Nucl Med , vol.42 , pp. 33-42
    • Baum, R.P.1    Brümmendorf, T.H.2
  • 58
    • 8544232152 scopus 로고    scopus 로고
    • Pre-operative assessment of axillary lymph node status in patients with breast adenocarcinoma using intravenous 99mtechnetium mAb-170H.82 (Tru-Scint AD)
    • S. Dessureault, I. Koven, R.M. Reilly et al., Pre-operative assessment of axillary lymph node status in patients with breast adenocarcinoma using intravenous 99mtechnetium mAb-170H.82 (Tru-Scint AD), Breast Cancer Res Treat 45 (1997), 29-37.
    • (1997) Breast Cancer Res Treat , vol.45 , pp. 29-37
    • Dessureault, S.1    Koven, I.2    Reilly, R.M.3
  • 59
    • 0030700632 scopus 로고    scopus 로고
    • Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
    • D. Neri, B. Carnemolla, A. Nissim et al., Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform, Nat Biotechnol 15 (1997), 1271-1275.
    • (1997) Nat Biotechnol , vol.15 , pp. 1271-1275
    • Neri, D.1    Carnemolla, B.2    Nissim, A.3
  • 60
    • 0032951071 scopus 로고    scopus 로고
    • In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
    • R. Weissleder, C.H. Tung, U. Mahmood and A. Bogdanov, In vivo imaging of tumors with protease-activated near-infrared fluorescent probes, Nat Biotechnol 17 (1999), 375-378.
    • (1999) Nat Biotechnol , vol.17 , pp. 375-378
    • Weissleder, R.1    Tung, C.H.2    Mahmood, U.3    Bogdanov, A.4
  • 61
    • 0034283034 scopus 로고    scopus 로고
    • In vivo imaging of proteolytic enzyme activity using a novel molecular reporter
    • C.H. Tung, U. Mahmood, S. Bredow and R. Weissleder, In vivo imaging of proteolytic enzyme activity using a novel molecular reporter, Cancer Res 60 (2000), 4953-4958.
    • (2000) Cancer Res , vol.60 , pp. 4953-4958
    • Tung, C.H.1    Mahmood, U.2    Bredow, S.3    Weissleder, R.4
  • 62
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • C. Bremer, C.H. Tung and R. Weissleder, In vivo molecular target assessment of matrix metalloproteinase inhibition, Nat Med 7 (2001), 743-748.
    • (2001) Nat Med , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.H.2    Weissleder, R.3
  • 65
    • 4344679634 scopus 로고    scopus 로고
    • Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide
    • K. Kelly, H. Alencar, M. Funovics, U. Mahmood and R. Weissleder, Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide, Cancer Res 64 (2004), 6247-6251.
    • (2004) Cancer Res , vol.64 , pp. 6247-6251
    • Kelly, K.1    Alencar, H.2    Funovics, M.3    Mahmood, U.4    Weissleder, R.5
  • 66
    • 33749042410 scopus 로고    scopus 로고
    • In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice
    • J.R. Newton, K.A. Kelly, U. Mahmood, R. Weissleder and S.L. Deutscher, In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice, Neoplasia 8 (2006), 772-780.
    • (2006) Neoplasia , vol.8 , pp. 772-780
    • Newton, J.R.1    Kelly, K.A.2    Mahmood, U.3    Weissleder, R.4    Deutscher, S.L.5
  • 68
    • 40149084977 scopus 로고    scopus 로고
    • Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene
    • A. Akyol, T. Hinoi, Y. Feng, G.T. Bommer, T.M. Glaser and E.R. Fearon, Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene, Nat Methods 5 (2008), 231-233.
    • (2008) Nat Methods , vol.5 , pp. 231-233
    • Akyol, A.1    Hinoi, T.2    Feng, Y.3    Bommer, G.T.4    Glaser, T.M.5    Fearon, E.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.