Comorbidity, age, race and stage at diagnosis in colorectal cancer: A retrospective, parallel analysis of two health systems

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Yousuf, S Yousuf ^a,c   Abernethy, Amy P ^a,b   Abbott, David H ^c   Grambow, Steven C ^a,c   Marcello, Jennifer E ^a   Herndon, James E ^a   Rowe, Krista L ^a   Kolimaga, Jane T ^a,c   Zullig, Leah L ^c   Patwardhan, Meenal B ^a,c   Provenzale, Dawn T ^a,c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b FLINDERS UNIVERSITY   (Australia)

^c DURHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CAUCASIAN; COHORT ANALYSIS; COLORECTAL CANCER; COMORBIDITY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HEALTH CARE SYSTEM; HEALTH CARE UTILIZATION; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; METASTASIS; ONSET AGE; PARALLEL DESIGN; POPULATION RESEARCH; RACE DIFFERENCE; RETROSPECTIVE STUDY; UNITED STATES;

EID: 58149385506     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-345     Document Type: Article

References (58)

1. Ferlay J Autier P Boniol M Heanue M Colombet M Boyle P Estimates of the cancer incidence and mortality in Europe in 2006 Ann Oncol 2007, 18(3):581-592 10.1093/annonc/mdl498 17287242
2. Jemal A Siegel R Ward E Murray T Xu J Thun MJ Cancer statistics, 2007 CA Cancer J Clin 2007, 57:34-66
3. National Cancer Institute SEER Cancer Statistics Review 1975-2003 http://seer.cancer.gov/csr/1975_2003/results_merged/ sect_06_colon_rectum.pdf
4. Firat S Pleister A Byhardt RW Gore E Age is independent of comorbidity influencing patient selection for combined modality therapy for treatment of stage III nonsmall cell lung cancer (NSCLC) Am J Clin Oncol 2006, 29(3):252-257 10.1097/01.coc.0000217824.20290.ab 16755178
5. Hawfield A Lovato J Covington D Kimmick G Retrospective study of the effect of comorbidity on use of adjuvant chemotherapy in older women with breast cancer in a tertiary care setting Crit Rev Oncol Hematol 2006, 59(3):250-255 10.1016/j.critrevonc.2005.12.004 16527489
6. Lemmens VE van Halteren AH Janssen-Heijnen ML Vreugdenhil G Repelaer van Driel OJ Coebergh JW Adjuvant treatment for elderly patients with stage III colon cancer in the southern Netherlands is affected by socioeconomic status, gender, and comorbidity Ann Oncol 2005, 16(5):767-772 10.1093/annonc/mdi159 15817594
7. Seve P Sawyer M Hanson J Broussolle C Dumontet C Mackey JR The influence of comorbidities, age, and performance status on the prognosis and treatment of patients with metastatic carcinomas of unknown primary site: a population-based study Cancer 2006, 106(9):2058-2066 10.1002/ cncr.21833 16583433
8. Cronin DP Harlan LC Potosky AL Clegg LX Stevens JL Mooney MM Patterns of care for adjuvant therapy in a random population-based sample of patients diagnosed with colorectal cancer Am J Gastroenterol 2006, 101(10):2308-2318 10.1111/j.1572-0241.2006.00775.x 17032196
9. Griggs JJ Culakova E Sorbero ME Poniewierski MS Wolff DA Crawford J Dale DC Lyman GH Social and racial differences in selection of breast cancer adjuvant chemotherapy regimens J Clin Oncol 2007, 25(18):2522-2527 10.1200/JCO.2006.10.2749 17577029
10. Ramsey SD Howlader N Etzioni RD Donato B Chemotherapy use, outcomes, and costs for older persons with advanced non-small-cell lung cancer: evidence from surveillance, epidemiology and end results Medicare. J Clin Oncol 2004, 22(24):4971-4978 10.1200/JCO.2004.05.031
11. Ward E Halpern M Schrag N Cokkinides V DeSantis C Bandi P Siegel R Stewart A Jemal A Association of insurance with cancer care utilization and outcomes CA Cancer J Clin 2008, 58(1):9-31 10.3322/CA.2007.0011 18096863
12. Halpern MT Bian J Ward EM Schrag NM Chen AY Insurance status and stage of cancer at diagnosis among women with breast cancer Cancer 2007, 110(2):403-411 10.1002/cncr.22786 17562557
13. Health, United States http://www.cdc.gov/nchs/data/hus/hus07.pdf
14. Oddone EZ Petersen LA Weinberger M Freedman J Kressin NR Contribution of the Veterans Health Administration in understanding racial disparities in access and utilization of health care: a spirit of inquiry Med Care 2002, 40(1 Suppl):I3-13 11789629
15. Kerr EA Gerzoff RB Krein SL Selby JV Piette JD Curb JD Herman WH Marrero DG Narayan KM Safford MM et al. Diabetes care quality in the Veterans Affairs Health Care System and commercial managed care: the TRIAD study Ann Intern Med 2004, 141(4):272-281 15313743
16. Jha AK Perlin JB Kizer KW Dudley RA Effect of the transformation of the Veterans Affairs Health Care System on the quality of care N Engl J Med 2003, 348(22):2218-2227 10.1056/NEJMsa021899 12773650
17. Ayanian JZ Chrischilles EA Fletcher RH Fouad MN Harrington DP Kahn KL Kiefe CI Lipscomb J Malin JL Potosky AL et al. Understanding cancer treatment and outcomes: the Cancer Care Outcomes Research and Surveillance Consortium J Clin Oncol 2004, 22:2992-2996 10.1200/ JCO.2004.06.020 15284250
18. Abernethy AP Patwardhan M Herndon JE Dowell J Rowe K Martin MG Zafar YMAM Tracking performance: Can oncology practices respond to the new quality measures? American Society of Clinical Oncology Gastrointestinal Cancers Symposium: 2007; Orlando, FL 2007
19. World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects http://www.wma.net/e/ policy/b3.htm
20. Deyo RA Cherkin DC Ciol MA Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases J Clin Epidemiol 1992, 45:613-619 10.1016/0895-4356(92)90133-8 1607900
21. Charlson ME Pompei P Ales Kl MacKenzie CR A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chron Dis 1987, 40:373-383 10.1016/0021-9681(87)90171-8 3558716
22. Galbraith RF A note on graphical presentation of estimated odds ratios from several clinical trials Statistics in medicine 1988, 7(8):889-894 10.1002/sim.4780070807 3413368
23. Anthony T Hynan LS D R The association of pretreatment health-related quality of life with surgical complications for patients undergoing open surgical resection for colorectal cancer Ann Surg 2003, 238:690-696 1356147 14578731 10.1097/01.sla.0000094304.17672.6e
24. Bach PB Schrag D Brawley OW et al. Survival of whites and blacks after a cancer diagnosis JAMA 2002, 287:2106-2113 10.1001/jama.287.16.2106 11966385
25. Colorectal Cancer Collaborative Group Surgery for colorectal cancer in elderly patients: a systematic review Lancet 2000, 356:968-974 10.1016/ S0140-6736(00)02713-6 11041397
26. Luo R Giordano SH Freeman JL et al. Referral to medical oncology: a crucial step in the treatment of older patients with stage III colon cancer Oncologist 2006, 11:1025-1033 1913211 17030645 10.1634/ theoncologist.11-9-1025
27. Neugent AI Matasar M Wang X et al. Duration of adjuvant chemotherapy for colon cancer and survival among the elderly J Clin Oncol 2006, 24:2368-2375 10.1200/JCO.2005.04.5005 16618946
28. Ong S Watters JM E G Predictors for referral for adjuvant therapy for colorectal cancer Can J Surg 2005, 48:225-229 16013627
29. Ouellette JR Small DG PM T Evaluation of Charlson-Age Comorbidity Index as predictor of morbidity and mortality in patients with colorectal carcinoma J Gastrointest Surg 2004, 8:1061-1067 10.1016/ j.gassur.2004.09.045 15585394
30. Gross CP McAvay GJ Guo Z Tinetti ME The impact of chronic illnesses on the use and effectiveness of adjuvant chemotherapy for colon cancer Cancer 2007, 109(12):2410-2419 10.1002/cncr.22726 17510973
31. Nelson KM Chapko MK Reiber G Boyko EJ The association between health insurance coverage and diabetes care; data from the 2000 Behavioral Risk Factor Surveillance System Health Serv Res 2005, 40(2):361-372 1361145 15762896 10.1111/j.1475-6773.2005.0d362.x
32. Medical Expenditure Panel Survey, Complete Set of Health Insurance Coverage Series in PDF Format, first half of 2001 http://www.meps.ahrq.gov/mepsweb/data_stats/summ_tables/hc/ hlth_insr/2001/alltables.pdf
33. 2001 National Survey of Veterans, Demographics http://www1.va.gov/ vetdata/docs/Table_11_112.pdf
34. 2001 National Survey of Veterans, Health Status http://www1.va.gov/ vetdata/docs/Table_31_310.pdf
35. Wilson NJ Kizer KW The VA health care system: An unrecognized safety net Health Aff 1997, 16:200-204 10.1377/hlthaff.16.4.200
36. Crawford J Cohen HJ Aging and neoplasia Annu Rev Gerontol Geriatr 1984, 4:3-32 6443553
37. Yang YX Hennessy S Lewis JD Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients Gastroenterology 2004, 127(4):1044-1050 10.1053/j.gastro.2004.07.011 15480982
38. Shayne M Culakova E Poniewierski MS Wolff D Dale DC Crawford J Lyman GH Dose intensity and hematologic toxicity in older cancer patients receiving systemic chemotherapy Cancer 2007, 110(7):1611-1620 10.1002/ cncr.22939 17705197
39. Berardi R Saladino T Mari D Silva RR Scartozzi M Verdecchia L Onofri A Cascinu S Elderly patients with advanced colorectal cancer: tolerability and activity of chemotherapy Tumori 2005, 91(6):463-466 16457142
40. Goldberg RM Tabah-Fisch I Bleiberg H de Gramont A Tournigand C Andre T Rothenberg ML Green E Sargent DJ Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancer J Clin Oncol 2006, 24(25):4085-4091 10.1200/JCO.2006.06.9039 16943526
41. Sanoff HK Bleiberg H Goldberg RM Managing older patients with colorectal cancer J Clin Oncol 2007, 25(14):1891-1897 10.1200/JCO.2006.10.1220 17488988
42. Hall SF A user's guide to selecting a comorbidity index for clinical research J Clin Epidemiol 2006, 59:849-855 10.1016/ j.jclinepi.2005.11.013 16828679
43. Cooper GS Fortinsky RH Hapke R Landefeld CS Primary care physician recommendations for colorectal cancer screening. Patient and practitioner factors Arch Int Med 1997, 157:1946-1950 10.1001/ archinte.157.17.1946
44. Fisher DA Judd L Sanford NS Inappropriate colorectal cancer screening: findings and implications Am J Gastroenterol 2005, 100(11):2526-2530 10.1111/j.1572-0241.2005.00322.x 16279910
45. Garman KS Jeffreys A Coffman C et al. Colorectal cancer screening, comorbidity, and follow-up in elderly patients Am J Med Sci 2006, 332:159-163 10.1097/00000441-200610000-00001 17031239
46. Sultan S Conway J Edelman D Dudley T Provenzale D Colorectal cancer screening in young patients with poor health and severe comorbidity Arch Intern Med 2006, 166(20):2209-2214 10.1001/archinte.166.20.2209 17101938
47. Subramanian S Klosterman M Amonkar MM Hunt TL Adherence with colorectal cancer screening guidelines: a review Prev Med 2004, 38(5):536-550 10.1016/j.ypmed.2003.12.011 15066356
48. Dolan NC Ferreira MR Fitzgibbon ML Davis TC Rademaker AW Liu D Lee J Wolf M Schmitt BP Bennett CL Colorectal cancer screening among African-American and white male veterans Am J Prev Med 2005, 28(5):479-482 10.1016/j.amepre.2005.02.002 15894152
49. Colorectal cancer test use among persons aged > or = 50 years - United States, 2001 MMWR Morb Mortal Wkly Rep 2003, 52(10):193-196 12653456
50. Dominitz JA Samsa GP Landsman P Provenzale D Race, treatment, and survival among colorectal carcinoma patients in an equal-access medical system Cancer 1998, 82:2312-2320 10.1002/ (SICI)1097-0142(19980615)82:12<2312::AID-CNCR3>3.0.CO;2-U 9635522
51. De Marco MF Janssen-Heijnen ML Heijden van der LH Coebergh JW Comorbidity and colorectal cancer according to subsite and stage: a population-based study Eur J Cancer 2000, 36:95-99 10.1016/ S0959-8049(99)00221-X 10741301
52. Gonzalez EC Ferrante JM Van Durme DJ Pal N Roetzheim RG Comorbid illness and the early detection of cancer South Med J 2001, 94:913-920 11592754
53. Geraci JM Escalante CP Freeman JL Goodwin JS Comorbid disease and cancer: the need for more relevant conceptual models in health services research J Clin Oncol 2005, 23:7399-7404 1853249 16234509 10.1200/ JCO.2004.00.9753
54. Fleming ST Pursley HG Newman B Pavlov D Chen K Comorbidity as a predictor of stage of illness for patients with breast cancer Med Care 2005, 43(2):132-140 10.1097/00005650-200502000-00006 15655426
55. Demark-Wahnefried W Aziz NM Rowland JH Pinto BM Riding the crest of the teachable moment: promoting long-term health after the diagnosis of cancer J Clin Oncol 2005, 23(24):5814-5830 1550285 16043830 10.1200/ JCO.2005.01.230
56. Langer CJ Neglected and underrepresented subpopulations: elderly and performance status 2 patients with advanced-stage non-small-cell lung cancer Clin Lung Cancer 2006(Suppl 4):S126-137 10.3816/CLC.2006.s.004
57. Adams-Campbell LL Ahaghotu C Gaskins M Dawkins FW Smoot D Polk OD Gooding R DeWitty RL Enrollment of African Americans onto clinical treatment trials: study design barriers J Clin Oncol 2004, 22:730-734 10.1200/JCO.2004.03.160 14966098
58. Aapro MS Kohne CH Cohen HJ Extermann M Never too old? Age should not be a barrier to enrollment in cancer clinical trials Oncologist 2005, 10:198-204 10.1634/theoncologist.10-3-198 15793223