메뉴 건너뛰기




Volumn 28, Issue 50, 2008, Pages 13478-13487

Mutation of a TADR protein leads to rhodopsin and Gq-dependent retinal degeneration in Drosophila

Author keywords

Cation amino acid transporter; Drosophila; G protein; GPCR; Photoreceptor; Retinal degeneration; Rhodopsin

Indexed keywords

DROSOPHILA PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C; PROTEIN TADR; RHODOPSIN; UNCLASSIFIED DRUG;

EID: 58149383269     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2122-08.2008     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 0033636313 scopus 로고    scopus 로고
    • The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration
    • Alloway PG, Howard L, Dolph PJ (2000) The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration. Neuron 28:129-138.
    • (2000) Neuron , vol.28 , pp. 129-138
    • Alloway, P.G.1    Howard, L.2    Dolph, P.J.3
  • 2
    • 0035977135 scopus 로고    scopus 로고
    • Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes
    • Blackshaw S, Fraioli RE, Furukawa T, Cepko CL (2001) Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell 107:579-589.
    • (2001) Cell , vol.107 , pp. 579-589
    • Blackshaw, S.1    Fraioli, R.E.2    Furukawa, T.3    Cepko, C.L.4
  • 4
    • 7244247244 scopus 로고    scopus 로고
    • Light-dependent subcellular translocation of Gqalpha in Drosophila photoreceptors is facilitated by the photoreceptor-specific myosin III NINAC
    • Cronin MA, Diao F, Tsunoda S (2004) Light-dependent subcellular translocation of Gqalpha in Drosophila photoreceptors is facilitated by the photoreceptor-specific myosin III NINAC. J Cell Sci 117:4797-4806.
    • (2004) J Cell Sci , vol.117 , pp. 4797-4806
    • Cronin, M.A.1    Diao, F.2    Tsunoda, S.3
  • 5
    • 33846957381 scopus 로고    scopus 로고
    • Perspective on genes and mutations causing retinitis pigmentosa
    • Daiger SP, Bowne SJ, Sullivan LS (2007) Perspective on genes and mutations causing retinitis pigmentosa. Arch Ophthalmol 125:151-158.
    • (2007) Arch Ophthalmol , vol.125 , pp. 151-158
    • Daiger, S.P.1    Bowne, S.J.2    Sullivan, L.S.3
  • 7
    • 0033744611 scopus 로고    scopus 로고
    • Molecular genetics of Oguchi disease, fundus albipunctatus, and other forms of stationary night blindness: LVII Edward Jackson Memorial Lecture
    • Dryja TP (2000) Molecular genetics of Oguchi disease, fundus albipunctatus, and other forms of stationary night blindness: LVII Edward Jackson Memorial Lecture. Am J Ophthalmol 130:547-563.
    • (2000) Am J Ophthalmol , vol.130 , pp. 547-563
    • Dryja, T.P.1
  • 8
    • 33646184680 scopus 로고    scopus 로고
    • ARF proteins: Roles in membrane traffic and beyond
    • D'Souza-Schorey C, Chavrier P (2006) ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol 7:347-358.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 347-358
    • D'Souza-Schorey, C.1    Chavrier, P.2
  • 9
    • 27744476340 scopus 로고    scopus 로고
    • Excess of Gbetae over Gqalphae in vivo prevents dark, spontaneous activity of Drosophila photoreceptors
    • Elia N, Frechter S, Gedi Y, Minke B, Selinger Z (2005) Excess of Gbetae over Gqalphae in vivo prevents dark, spontaneous activity of Drosophila photoreceptors. J Cell Biol 171:517-526.
    • (2005) J Cell Biol , vol.171 , pp. 517-526
    • Elia, N.1    Frechter, S.2    Gedi, Y.3    Minke, B.4    Selinger, Z.5
  • 10
    • 0015149417 scopus 로고
    • Pseudopupil phenomena in the compound eye of drosophila]
    • Franceschini N, Kirschfeld K (1971) [Pseudopupil phenomena in the compound eye of drosophila]. Kybernetik 9:159-182.
    • (1971) Kybernetik , vol.9 , pp. 159-182
    • Franceschini, N.1    Kirschfeld, K.2
  • 11
    • 34250654475 scopus 로고    scopus 로고
    • Translocation of Gq alpha mediates long-term adaptation in Drosophila photoreceptors
    • Frechter S, Elia N, Tzarfaty V, Selinger Z, Minke B (2007) Translocation of Gq alpha mediates long-term adaptation in Drosophila photoreceptors. J Neurosci 27:5571-5583.
    • (2007) J Neurosci , vol.27 , pp. 5571-5583
    • Frechter, S.1    Elia, N.2    Tzarfaty, V.3    Selinger, Z.4    Minke, B.5
  • 12
    • 0029067542 scopus 로고
    • A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese
    • Fuchs S, Nakazawa M, Maw M, Tamai M, Oguchi Y, Gal A (1995) A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese. Nat Genet 10:360-362.
    • (1995) Nat Genet , vol.10 , pp. 360-362
    • Fuchs, S.1    Nakazawa, M.2    Maw, M.3    Tamai, M.4    Oguchi, Y.5    Gal, A.6
  • 14
    • 33750797568 scopus 로고    scopus 로고
    • The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor
    • Han J, Gong P, Reddig K, Mitra M, Guo P, Li HS (2006) The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. Cell 127:847-858.
    • (2006) Cell , vol.127 , pp. 847-858
    • Han, J.1    Gong, P.2    Reddig, K.3    Mitra, M.4    Guo, P.5    Li, H.S.6
  • 16
    • 0026583241 scopus 로고
    • The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors
    • Hardie RC, Minke B (1992) The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors. Neuron 8:643-651.
    • (1992) Neuron , vol.8 , pp. 643-651
    • Hardie, R.C.1    Minke, B.2
  • 17
    • 0035855910 scopus 로고    scopus 로고
    • Visual transduction in Drosophila
    • Hardie RC, Raghu P (2001) Visual transduction in Drosophila. Nature 413:186-193.
    • (2001) Nature , vol.413 , pp. 186-193
    • Hardie, R.C.1    Raghu, P.2
  • 20
    • 0037072774 scopus 로고    scopus 로고
    • Single amino acid change in the fifth transmembrane segment of the TRP Ca2+ channel causes massive degeneration of photoreceptors
    • Hong YS, Park S, Geng C, Baek K, Bowman JD, Yoon J, Pak WL (2002) Single amino acid change in the fifth transmembrane segment of the TRP Ca2+ channel causes massive degeneration of photoreceptors. J Biol Chem 277:33884-33889.
    • (2002) J Biol Chem , vol.277 , pp. 33884-33889
    • Hong, Y.S.1    Park, S.2    Geng, C.3    Baek, K.4    Bowman, J.D.5    Yoon, J.6    Pak, W.L.7
  • 21
    • 1542267743 scopus 로고    scopus 로고
    • Novel dominant rhodopsin mutation triggers two mechanisms of retinal degeneration and photoreceptor desensitization
    • Iakhine R, Chorna-Ornan I, Zars T, Elia N, Cheng Y, Selinger Z, Minke B, Hyde DR (2004) Novel dominant rhodopsin mutation triggers two mechanisms of retinal degeneration and photoreceptor desensitization. J Neurosci 24:2516-2526.
    • (2004) J Neurosci , vol.24 , pp. 2516-2526
    • Iakhine, R.1    Chorna-Ornan, I.2    Zars, T.3    Elia, N.4    Cheng, Y.5    Selinger, Z.6    Minke, B.7    Hyde, D.R.8
  • 22
    • 0028287273 scopus 로고
    • Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa
    • Kaushal S, Khorana HG (1994) Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry 33:6121-6128.
    • (1994) Biochemistry , vol.33 , pp. 6121-6128
    • Kaushal, S.1    Khorana, H.G.2
  • 25
    • 0028947292 scopus 로고
    • Retinal degeneration caused by dominant rhodopsin mutations in Drosophila
    • Kurada P, O'Tousa JE (1995) Retinal degeneration caused by dominant rhodopsin mutations in Drosophila. Neuron 14:571-579.
    • (1995) Neuron , vol.14 , pp. 571-579
    • Kurada, P.1    O'Tousa, J.E.2
  • 26
    • 0027940261 scopus 로고
    • The Drosophila dgq gene encodes a G alpha protein that mediates phototransduction
    • Lee YJ, Shah S, Suzuki E, Zars T, O'Day PM, Hyde DR (1994) The Drosophila dgq gene encodes a G alpha protein that mediates phototransduction. Neuron 13:1143-1157.
    • (1994) Neuron , vol.13 , pp. 1143-1157
    • Lee, Y.J.1    Shah, S.2    Suzuki, E.3    Zars, T.4    O'Day, P.M.5    Hyde, D.R.6
  • 27
    • 0026778182 scopus 로고
    • Degeneration of photoreceptors in rhodopsin mutants of Drosophila
    • Leonard DS, Bowman VD, Ready DF, Pak WL (1992) Degeneration of photoreceptors in rhodopsin mutants of Drosophila. J Neurobiol 23:605-626.
    • (1992) J Neurobiol , vol.23 , pp. 605-626
    • Leonard, D.S.1    Bowman, V.D.2    Ready, D.F.3    Pak, W.L.4
  • 28
    • 0034683664 scopus 로고    scopus 로고
    • TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells
    • Li HS, Montell C (2000) TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells. J Cell Biol 150:1411-1422.
    • (2000) J Cell Biol , vol.150 , pp. 1411-1422
    • Li, H.S.1    Montell, C.2
  • 29
    • 38449103389 scopus 로고    scopus 로고
    • Diverse roles of Rho family GTPases in neuronal development, survival, and death
    • Linseman DA, Loucks FA (2008) Diverse roles of Rho family GTPases in neuronal development, survival, and death. Front Biosci 13:657-676.
    • (2008) Front Biosci , vol.13 , pp. 657-676
    • Linseman, D.A.1    Loucks, F.A.2
  • 30
    • 15744364175 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA
    • Lutz S, Freichel-Blomquist A, Yang Y, Rümenapp U, Jakobs KH, Schmidt M, Wieland T (2005) The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA. J Biol Chem 280:11134-11139.
    • (2005) J Biol Chem , vol.280 , pp. 11134-11139
    • Lutz, S.1    Freichel-Blomquist, A.2    Yang, Y.3    Rümenapp, U.4    Jakobs, K.H.5    Schmidt, M.6    Wieland, T.7
  • 32
    • 0027429547 scopus 로고
    • Drosophila retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteinerich zinc-finger motifs and ankyrin repeats
    • Masai I, Okazaki A, Hosoya T, Hotta Y (1993) Drosophila retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteinerich zinc-finger motifs and ankyrin repeats. Proc Natl Acad Sci U S A 90:11157-11161.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11157-11161
    • Masai, I.1    Okazaki, A.2    Hosoya, T.3    Hotta, Y.4
  • 33
    • 0023449303 scopus 로고
    • Studies of the Drosophila norpA phototransduction mutant. II. Photoreceptor degeneration and rhodopsin maintenance
    • Meyertholen EP, Stein PJ, Williams MA, Ostroy SE (1987) Studies of the Drosophila norpA phototransduction mutant. II. Photoreceptor degeneration and rhodopsin maintenance. J Comp Physiol [A] 161:793-798.
    • (1987) J Comp Physiol , vol.161 , Issue.A , pp. 793-798
    • Meyertholen, E.P.1    Stein, P.J.2    Williams, M.A.3    Ostroy, S.E.4
  • 34
    • 0033280228 scopus 로고    scopus 로고
    • Visual transduction in Drosophila
    • Montell C (1999) Visual transduction in Drosophila. Annu Rev Cell Dev Biol 15:231-268.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 231-268
    • Montell, C.1
  • 35
    • 0024316107 scopus 로고
    • The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells
    • Moses K, Ellis MC, Rubin GM (1989) The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells. Nature 340:531-536.
    • (1989) Nature , vol.340 , pp. 531-536
    • Moses, K.1    Ellis, M.C.2    Rubin, G.M.3
  • 36
    • 0036181285 scopus 로고    scopus 로고
    • Loss of the phospholipase C gene product induces massive endocytosis of rhodopsin and arrestin in Drosophila photoreceptors
    • Orem NR, Dolph PJ (2002) Loss of the phospholipase C gene product induces massive endocytosis of rhodopsin and arrestin in Drosophila photoreceptors. Vision Res 42:497-505.
    • (2002) Vision Res , vol.42 , pp. 497-505
    • Orem, N.R.1    Dolph, P.J.2
  • 38
    • 0033679832 scopus 로고    scopus 로고
    • Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA
    • Raghu P, Usher K, Jonas S, Chyb S, Polyanovsky A, Hardie RC (2000) Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA. Neuron 26:169-179.
    • (2000) Neuron , vol.26 , pp. 169-179
    • Raghu, P.1    Usher, K.2    Jonas, S.3    Chyb, S.4    Polyanovsky, A.5    Hardie, R.C.6
  • 39
    • 0037436537 scopus 로고    scopus 로고
    • Cell biology. A matter of life or death
    • Ranganathan R (2003) Cell biology. A matter of life or death. Science 299:1677-1679.
    • (2003) Science , vol.299 , pp. 1677-1679
    • Ranganathan, R.1
  • 41
    • 35748983198 scopus 로고    scopus 로고
    • Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain
    • Rojas RJ, Yohe ME, Gershburg S, Kawano T, Kozasa T, Sondek J (2007) Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain. J Biol Chem 282:29201-29210.
    • (2007) J Biol Chem , vol.282 , pp. 29201-29210
    • Rojas, R.J.1    Yohe, M.E.2    Gershburg, S.3    Kawano, T.4    Kozasa, T.5    Sondek, J.6
  • 42
    • 26244448851 scopus 로고    scopus 로고
    • Arrestin1 mediates light-dependent rhodopsin endocytosis and cell survival
    • Satoh AK, Ready DF (2005) Arrestin1 mediates light-dependent rhodopsin endocytosis and cell survival. Curr Biol 15:1722-1733.
    • (2005) Curr Biol , vol.15 , pp. 1722-1733
    • Satoh, A.K.1    Ready, D.F.2
  • 43
    • 0028972614 scopus 로고
    • Gq alpha protein function in vivo: Genetic dissection of its role in photoreceptor cell physiology
    • Scott K, Becker A, Sun Y, Hardy R, Zuker C (1995) Gq alpha protein function in vivo: genetic dissection of its role in photoreceptor cell physiology. Neuron 15:919-927.
    • (1995) Neuron , vol.15 , pp. 919-927
    • Scott, K.1    Becker, A.2    Sun, Y.3    Hardy, R.4    Zuker, C.5
  • 45
    • 34250890832 scopus 로고    scopus 로고
    • Phototransduction and retinal degeneration in Drosophila
    • Wang T, Montell C (2007) Phototransduction and retinal degeneration in Drosophila. Pflugers Arch 454:821-847.
    • (2007) Pflugers Arch , vol.454 , pp. 821-847
    • Wang, T.1    Montell, C.2
  • 46
    • 27944508336 scopus 로고    scopus 로고
    • Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel
    • Wang T, Jiao Y, Montell C (2005) Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel. J Cell Biol 171:685-694.
    • (2005) J Cell Biol , vol.171 , pp. 685-694
    • Wang, T.1    Jiao, Y.2    Montell, C.3
  • 47
    • 0742321905 scopus 로고    scopus 로고
    • The nature of dominant mutations of rhodopsin and implications for gene therapy
    • Wilson JH, Wensel TG (2003) The nature of dominant mutations of rhodopsin and implications for gene therapy. Mol Neurobiol 28:149-158.
    • (2003) Mol Neurobiol , vol.28 , pp. 149-158
    • Wilson, J.H.1    Wensel, T.G.2
  • 48
    • 0037097030 scopus 로고    scopus 로고
    • Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity
    • Wolf S, Janzen A, Vékony N, Martiné U, Strand D, Closs EI (2002) Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. Biochem J 364:767-775.
    • (2002) Biochem J , vol.364 , pp. 767-775
    • Wolf, S.1    Janzen, A.2    Vékony, N.3    Martiné, U.4    Strand, D.5    Closs, E.I.6
  • 49
    • 0031038950 scopus 로고    scopus 로고
    • Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness
    • Yamamoto S, Sippel KC, Berson EL, Dryja TP (1997) Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness. Nat Genet 15:175-178.
    • (1997) Nat Genet , vol.15 , pp. 175-178
    • Yamamoto, S.1    Sippel, K.C.2    Berson, E.L.3    Dryja, T.P.4
  • 50
    • 0141836779 scopus 로고    scopus 로고
    • Mutation of the photoreceptor specific homeodomain gene Pph13 results in defects in phototransduction and rhabdomere morphogenesis
    • Zelhof AC, Koundakjian E, Scully AL, Hardy RW, Pounds L (2003) Mutation of the photoreceptor specific homeodomain gene Pph13 results in defects in phototransduction and rhabdomere morphogenesis. Development 130:4383-4392.
    • (2003) Development , vol.130 , pp. 4383-4392
    • Zelhof, A.C.1    Koundakjian, E.2    Scully, A.L.3    Hardy, R.W.4    Pounds, L.5
  • 51
    • 0025516472 scopus 로고
    • Microphotometric, ultrastructural, and electrophysiological analyses of light-dependent processes on visual receptors in white-eyed wild-type and norpA (no receptor potential) mutant Drosophila
    • Zinkl GM, Maier L, Studer K, Sapp R, Chen DM, Stark WS (1990) Microphotometric, ultrastructural, and electrophysiological analyses of light-dependent processes on visual receptors in white-eyed wild-type and norpA (no receptor potential) mutant Drosophila. Vis Neurosci 5:429-439.
    • (1990) Vis Neurosci , vol.5 , pp. 429-439
    • Zinkl, G.M.1    Maier, L.2    Studer, K.3    Sapp, R.4    Chen, D.M.5    Stark, W.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.