Promoter analysis suggests the implication of NFκB/c-Rel transcription factors in biliary atresia

Hepato-Gastroenterology

Volumn 55, Issue 85, 2008, Pages 1189-1192

  Gyorffy, András ^a   Baranyai, Zsolt ^b   Cseh, Áron ^a   Munkácsy, Gyöngyi ^a   Jakab, Ferenc ^b   Tulassay, Zsolt ^a   Gyorffy, Balazs ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UZSOKI HOSPITAL   (Hungary)

Author keywords

Gene regulation; Microarray; Perinatal biliary atresia; Promoter region; Transcription factor binding site

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

BILE DUCT ATRESIA; DNA MICROARRAY; HUMAN; PHYSIOLOGY; PROMOTER REGION; REVIEW;

BILIARY ATRESIA; HUMANS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC;

EID: 58149380616     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Sokol RJ, Mack C: Etiopathogenesis of biliary atresia. Semin Liver Dis 2001; 21:517-524. (Pubitemid 33131043)
2. Zhang DY, Sabla G, Shivakumar P, et al.: Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia. Hepatology 2004; 39:954-962. (Pubitemid 38428934)
3. Chen L, Goryachev A, Sun J, et al.: Altered expression of genes involved in hepatic morphogenesis and fibrogenesis are identified by cDNA microarray analysis in biliary atresia. Hepatology 2003; 38:567-576. (Pubitemid 37052144)
4. Bezerra JA, Tiao G, Ryckman FC, et al.: Genetic induction of proinflammatory immunity in children with biliary atresia. Lancet 2002; 360:1653-1659. (Pubitemid 35379738)
5. Aerts S, Thijs G, Coessens B, et al.: Toucan: deciphering the cis-regulatory logic of coregulated genes. Nucleic Acids Res 2003; 31:1753-1764. (Pubitemid 36336577)
6. Zhang H, Ramanathan Y, Soteropoulos P, et al.: EZ-Retrieve: a web-server for batch retrieval of coordinate-specified human DNA sequences and underscoring putative transcription factor-binding sites. Nucleic Acids Res 2002; 30:e121.
7. Wingender E, Chen X, Fricke E, et al.: The TRANSFAC system on gene expression regulation. Nucleic Acids Res 2001; 29:281-283. (Pubitemid 32054469)
8. Feng J, Li M, Cai T, et al.: Rotavirus-induced murine biliary atresia is mediated by nuclear factor-kappaB. J Pediatr Surg 2005; 40:630-636.
9. Liou HC, Hsia CY: Distinctions between c-Rel and other NFkappaB proteins in immunity and disease. Bioessays 2003; 25:767-780.
10. Mack C, Sokol RJ: Unraveling the pathogenesis and etiology of biliary atresia. Pediatr Res 2005; 57:87R-94R. (Pubitemid 40593251)
11. Mack CL, Tucker RM, Sokol RJ, et al.: Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Pediatr Res 2004; 56:79-87. (Pubitemid 38808546)
12. Fischler B, Ehrnst A, Forsgren M, et al.: The viral association of neonatal cholestasis in Sweden: a possible link between cytomegalovirus infection and extrahepatic biliary atresia. J Pediatr Gastroenterol Nutr 1998; 27:57-64. (Pubitemid 28293026)
13. Fjaer RB, Bruu AL, Nordbo SA: Extrahepatic bile duct atresia and viral involvement. Pediatr Transplant 2005; 9:68-73. (Pubitemid 40238967)
14. Morecki R, Glaser JH, Cho S, et al.: Biliary atresia and reovirus type 3 infection. N Engl J Med 1982; 307:481-484. (Pubitemid 12095137)
15. Richardson SC, Bishop RF, Smith AL: Reovirus serotype 3 infection in infants with extrahepatic biliary atresia or neonatal hepatitis. J Gastroenterol Hepatol 1994; 9:264-268. (Pubitemid 24149289)
16. Wilson GA, Morrision LA, Fields BN: Association of the reovirus Sl gene with serotype 3-induced biliary atresia in mice. J Virol 1994; 68:6458-6465. (Pubitemid 24294896)