An unusual case of gynecomastia associated with soy product consumption

Endocrine Practice

Volumn 14, Issue 4, 2008, Pages 415-418

  Martinez, Jorge ^a   Lewi, Jack E ^b  

^a BROOKE ARMY MEDICAL CENTER   (United States)

^b SAN ANTONIO MILITARY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DAIDZEIN; ESTRADIOL; ESTRONE; GENISTEIN; SEX HORMONE BINDING GLOBULIN;

ADULT; ARTICLE; BREAST TENDERNESS; CASE REPORT; DIET SUPPLEMENTATION; DIETARY INTAKE; ERECTILE DYSFUNCTION; FOOD COMPOSITION; FOOD INTAKE; GYNECOMASTIA; HUMAN; LIBIDO DISORDER; MALE; SOYBEAN MILK; BEVERAGE; MIDDLE AGED;

BEVERAGES; GYNECOMASTIA; HUMANS; MALE; MIDDLE AGED; SOY MILK;

EID: 58149378928     PISSN: 1530891X     EISSN: None     Source Type: Journal    
DOI: 10.4158/EP.14.4.415     Document Type: Article

References (22)

1. Narula HS, Carlson HE. Gynecomastia. Endocrinol Metab Clin N Am. 2007;36:497-519.
2. Bhasin S. Gynecomastia. In: Larsen PR, Kronenberg HM, Melmed, S, Polonsky KS, eds. Williams Textbook of Endocrinology. 10th ed. Philadelphia, PA: WB Saunders, 2003: 741-746.
3. Henley DV, Lipson N, Korach K, Block CA. Prepubertal gynecomastia linked to lavender and tea tree oils. N Engl J Med. 2007;356:479-485.
4. Goh SY, Loh KC. Gynaecomastia and the herbal tonic "Dong Quai." Singapore Med J. 2001;42:115-116.
5. Cakan N, Kamat D. Gynecomastia: evaluation and treatment recommendations for primary care providers. Clin Pediatr. 2007;46:487-490.
6. Braunstein GD. Gynecomastia. N Engl J Med. 1993;328: 490-495.
7. de Ronde W, van der Schouw YT, Muller M, et al. Associations of sex-hormone-binding globulin (SHBG) with non-SHBG-bound levels of testosterone and estradiol in independently living men. J Clin Endocrinol Metab. 2005;90:157-162.
8. Anderson JW, Johnstone BM, Cook-Newell ME. Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med. 1995;333:276-282.
9. Somekawa Y, Chiguchi M, Ishibashi T, Aso T. Soy intake related to menopausal symptoms, serum lipids, and bone mineral density in postmenopausal Japanese women. Obstet Gynecol. 2001;97:109-115.
10. Jacobsen BK, Knutsen SF, Fraser GE. Does high soy milk intake reduce prostate cancer incidence? The Adventist Health Study (United States). Cancer Causes Control. 1988;9:553-557.
11. Martínez ME, Thomson CA, Smith-Warner SA. Soy and breast cancer: the controversy continues. J Natl Cancer Inst. 2006;98:430-431.
12. Crisafulli A, Marini H, Bitto A, et al. Effects of genistein on hot flashes in early postmenopausal women: a randomized, double-blind EPT- and placebo-controlled study. Menopause. 2004;11:400-404.
13. Tham DM, Gardner CD, Haskell WL. Clinical review 97: Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab. 1998;83:2223-2235.
14. Marini H, Minutoli L, Polito F, et al. Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial. Ann Intern Med. 2007;146:839-847.
15. Lydeking-Olsen E, Beck-Jensen JE, Setchell KD, Holm-Jensen T. Soymilk or progesterone for prevention of bone loss - a 2 year randomized, placebo-controlled trial. Eur J Nutr. 2004;43:246-257.
16. Kostelac D, Rechkemmer G, Briviba K. Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element. J Agric Food Chem. 2003;51:7632-7635.
17. Setchell KD. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. Am J Clin Nutr. 1998;68(6 Suppl):1333-1346.
18. Atkinson C, Frankenfeld CL, Lampe JW. Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health. Exp Biol Med (Maywood). 2005;230:155-170.
19. Xu X, Duncan AM, Merz BE, Kurzer MS. Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. Cancer Epidemiol Biomarkers Prev. 1998;7:1101-1108.
20. Braunstein GD. Aromatase and gynecomastia. Endocr Relat Cancer. 1999;6:315-324.
21. Wiesman IM, Lehman JA Jr, Parker MG, Tantri MD, Wagner DS, Pedersen JC. Gynecomastia: an outcome analysis. Ann Plast Surg. 2004;53:97-101.
22. Andersen JA, Gram JB. Gynecomasty: histological aspects in a surgical material. Acta Pathol Microbiol Immunol Scand [A]. 1982;90:185-190.