메뉴 건너뛰기




Volumn 17, Issue 5, 2008, Pages 464-469

Does dosing antihypertensive drugs at night alter renal or cardiovascular outcome: Do we have the evidence?

Author keywords

Ambulatory blood pressure monitoring; Antihypertensive drugs; Bedtime dosing; Chronotherapy; Nighttime administration

Indexed keywords

ALBUMIN; AMLODIPINE PLUS BENAZEPRIL; ANTIHYPERTENSIVE AGENT; ATENOLOL; CARVEDILOL; CILNIDIPINE; DILTIAZEM; DOXAZOSIN; ENALAPRIL; GUANABENZ; HYDROCHLOROTHIAZIDE; METOPROLOL; NIFEDIPINE; NITRENDIPINE; PLACEBO; PROPRANOLOL; RAMIPRIL; VALSARTAN; VERAPAMIL;

EID: 58149350308     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNH.0b013e328305b983     Document Type: Review
Times cited : (14)

References (48)
  • 1
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure
    • Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Hypertension 2003; 42:1206-1252.
    • (2003) Hypertension , vol.42 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3
  • 3
    • 34948903820 scopus 로고    scopus 로고
    • Chronotherapy of hypertension: Administration-time-dependent effects of treatment on the circadian pattern of blood pressure
    • Hermida RC, Ayala DE, Calvo C, et al. Chronotherapy of hypertension: administration-time-dependent effects of treatment on the circadian pattern of blood pressure. Adv Drug Deliv Rev 2007; 59:923-939.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 923-939
    • Hermida, R.C.1    Ayala, D.E.2    Calvo, C.3
  • 4
    • 33746694167 scopus 로고    scopus 로고
    • The importance of circadian rhythms on drug response in hypertension and coronary heart disease from mice and man
    • Lemmer B. The importance of circadian rhythms on drug response in hypertension and coronary heart disease from mice and man. Pharmacol Ther 2006; 111:629-651.
    • (2006) Pharmacol Ther , vol.111 , pp. 629-651
    • Lemmer, B.1
  • 5
    • 12744263225 scopus 로고    scopus 로고
    • Circadian variations in blood pressure: Implications for chronotherapeutics
    • Hassler C, Burnier M. Circadian variations in blood pressure: implications for chronotherapeutics. Am J Cardiovasc Drugs 2005; 5:7-15.
    • (2005) Am J Cardiovasc Drugs , vol.5 , pp. 7-15
    • Hassler, C.1    Burnier, M.2
  • 6
    • 12444277817 scopus 로고    scopus 로고
    • Society of Hypertension Working Group on Blood Pressure Monitoring: European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurement
    • O'Brien E, Asmar R, Beilin L, et al. Society of Hypertension Working Group on Blood Pressure Monitoring: European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurement. J Hypertens 2003; 21:821 -848.
    • (2003) J Hypertens , vol.21 , pp. 821-848
    • O'Brien, E.1    Asmar, R.2    Beilin, L.3
  • 7
    • 21744446081 scopus 로고    scopus 로고
    • Superiority of ambulatory over clinic blood pressure measurement in predicting mortality
    • Dolan E, Stanton A, Thijs L, et al. Superiority of ambulatory over clinic blood pressure measurement in predicting mortality. Hypertension 2005; 46:156-161.
    • (2005) Hypertension , vol.46 , pp. 156-161
    • Dolan, E.1    Stanton, A.2    Thijs, L.3
  • 8
    • 17144375670 scopus 로고    scopus 로고
    • Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population: Follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study
    • Sega R, Facchetti R, Bombelli M, et al. Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population: follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study. Circulation 2005; 111:1777-1783.
    • (2005) Circulation , vol.111 , pp. 1777-1783
    • Sega, R.1    Facchetti, R.2    Bombelli, M.3
  • 9
    • 0033546609 scopus 로고    scopus 로고
    • Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. Systolic Hypertension in Europe Trial Investigators
    • Staessen JA, Thijs L, Fagard R, et al. Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. Systolic Hypertension in Europe Trial Investigators. JAMA 1999; 282:539-546.
    • (1999) JAMA , vol.282 , pp. 539-546
    • Staessen, J.A.1    Thijs, L.2    Fagard, R.3
  • 10
    • 0027998048 scopus 로고
    • Ambulatory blood pressure. An independent predictor of prognosis in essential hypertension
    • Verdecchia P, Porcellati C, Schillaci G, et al. Ambulatory blood pressure. An independent predictor of prognosis in essential hypertension. Hypertension 1994; 24:793-801.
    • (1994) Hypertension , vol.24 , pp. 793-801
    • Verdecchia, P.1    Porcellati, C.2    Schillaci, G.3
  • 11
    • 0024536680 scopus 로고
    • Circadian variation and triggers of onset of acute cardiovascular disease
    • Muller JE, Tofler GH, Stone PH. Circadian variation and triggers of onset of acute cardiovascular disease. Circulation 1989; 79:733-743.
    • (1989) Circulation , vol.79 , pp. 733-743
    • Muller, J.E.1    Tofler, G.H.2    Stone, P.H.3
  • 12
    • 0036284564 scopus 로고    scopus 로고
    • Parallel morning and evening surge in stroke onset, blood pressure, and physical activity
    • Stergiou GS, Vemmos KN, Pliarchopoulou KM, et al. Parallel morning and evening surge in stroke onset, blood pressure, and physical activity. Stroke 2002; 33:1480-1486.
    • (2002) Stroke , vol.33 , pp. 1480-1486
    • Stergiou, G.S.1    Vemmos, K.N.2    Pliarchopoulou, K.M.3
  • 13
    • 0037453061 scopus 로고    scopus 로고
    • Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives: A prospective study
    • Kario K, Pickering TG, Umeda Y, et al. Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives: a prospective study. Circulation 2003; 107:1401-1406.
    • (2003) Circulation , vol.107 , pp. 1401-1406
    • Kario, K.1    Pickering, T.G.2    Umeda, Y.3
  • 14
    • 31944434439 scopus 로고    scopus 로고
    • Prognostic significance for stroke of a morning pressor surge and a nocturnal blood pressure decline: The Ohasama study
    • Metoki H, Ohkubo T, Kikuya M, et al. Prognostic significance for stroke of a morning pressor surge and a nocturnal blood pressure decline: the Ohasama study. Hypertension 2006; 47:149-154.
    • (2006) Hypertension , vol.47 , pp. 149-154
    • Metoki, H.1    Ohkubo, T.2    Kikuya, M.3
  • 16
    • 33748951036 scopus 로고    scopus 로고
    • Morning hypertension: The strongest independent risk factor for stroke in elderly hypertensive patients
    • Kario K, Ishikawa J, Pickering TG, et al. Morning hypertension: the strongest independent risk factor for stroke in elderly hypertensive patients. Hypertens Res 2006; 29:581 -587.
    • (2006) Hypertens Res , vol.29 , pp. 581-587
    • Kario, K.1    Ishikawa, J.2    Pickering, T.G.3
  • 17
    • 0030199203 scopus 로고    scopus 로고
    • Trough/peak ratios of once daily angiotensin converting enzyme inhibitors and calcium antagonists
    • Zannad F, Matzinger A, Larche J. Trough/peak ratios of once daily angiotensin converting enzyme inhibitors and calcium antagonists. Am J Hypertens 1996; 9:633-643.
    • (1996) Am J Hypertens , vol.9 , pp. 633-643
    • Zannad, F.1    Matzinger, A.2    Larche, J.3
  • 18
    • 0036591588 scopus 로고    scopus 로고
    • Relationship between physical activity and blood pressure in dipper and nondipper hypertensive patients
    • Hermida RC, Calvo C, Ayala DE, et al. Relationship between physical activity and blood pressure in dipper and nondipper hypertensive patients. J Hypertens 2002; 20:1097-1104.
    • (2002) J Hypertens , vol.20 , pp. 1097-1104
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 19
    • 0041331792 scopus 로고    scopus 로고
    • Administration time-dependent effects of valsartan on ambulatory blood pressure in hypertensive subjects
    • Hermida RC, Calvo C, Ayala DE, et al. Administration time-dependent effects of valsartan on ambulatory blood pressure in hypertensive subjects. Hypertension 2003; 42:283-290.
    • (2003) Hypertension , vol.42 , pp. 283-290
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 20
    • 25444506196 scopus 로고    scopus 로고
    • Administration time-dependent effects of valsartan on ambulatory blood pressure in elderly hypertensive subjects
    • Hermida RC, Calvo C, Ayala DE, et al. Administration time-dependent effects of valsartan on ambulatory blood pressure in elderly hypertensive subjects. Chronobiol Int 2005; 22:755-776.
    • (2005) Chronobiol Int , vol.22 , pp. 755-776
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 21
    • 34548825662 scopus 로고    scopus 로고
    • Comparison of the efficacy of morning versus evening administration of telmisartan in essential hypertension
    • Hermida RC, Ayala DE, Fernandez JR, et al. Comparison of the efficacy of morning versus evening administration of telmisartan in essential hypertension. Hypertension 2007; 50:715-722.
    • (2007) Hypertension , vol.50 , pp. 715-722
    • Hermida, R.C.1    Ayala, D.E.2    Fernandez, J.R.3
  • 22
    • 29244476030 scopus 로고    scopus 로고
    • Treatment of nondipper hypertension with bedtime administration of valsartan
    • Hermida RC, Calvo C, Ayala DE, et al. Treatment of nondipper hypertension with bedtime administration of valsartan. J Hypertens 2005; 23:1913-1922.
    • (2005) J Hypertens , vol.23 , pp. 1913-1922
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 23
    • 0023831710 scopus 로고
    • Circadian changes in the pharmacokinetics and cardiovascular effects of oral propranolol in healthy subjects
    • Langner B, Lemmer B. Circadian changes in the pharmacokinetics and cardiovascular effects of oral propranolol in healthy subjects. Eur J Clin Pharmacol 1988; 33:619-624.
    • (1988) Eur J Clin Pharmacol , vol.33 , pp. 619-624
    • Langner, B.1    Lemmer, B.2
  • 24
    • 34249294973 scopus 로고    scopus 로고
    • Administration time-dependent effects of nebivolol on the diurnal/nocturnal blood pressure ratio in hypertensive patients [abstract]
    • Hermida RC, Calvo C, Ayala DE, et al. Administration time-dependent effects of nebivolol on the diurnal/nocturnal blood pressure ratio in hypertensive patients [abstract]. J Hypertens 2006; 24 (Suppl 4):S89.
    • (2006) J Hypertens , vol.24 , Issue.SUPPL. 4
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 25
    • 0034102923 scopus 로고    scopus 로고
    • Changes of nocturnal blood pressure dipping status in hypertensives by nighttime dosing of alpha-adrenergic blocker, doxazosin: Results from the HALT study
    • Kario K, Schwartz JE, Pickering TG. Changes of nocturnal blood pressure dipping status in hypertensives by nighttime dosing of alpha-adrenergic blocker, doxazosin: results from the HALT study. Hypertension 2000; 35:787-794.
    • (2000) Hypertension , vol.35 , pp. 787-794
    • Kario, K.1    Schwartz, J.E.2    Pickering, T.G.3
  • 26
    • 0029128810 scopus 로고
    • Nocturnal dosing of a novel delivery system of verapamil for systemic hypertension. Verapamil Study Group
    • White WB, Anders RJ, MacIntyre JM, et al. Nocturnal dosing of a novel delivery system of verapamil for systemic hypertension. Verapamil Study Group. Am J Cardiol 1995; 76:375-380.
    • (1995) Am J Cardiol , vol.76 , pp. 375-380
    • White, W.B.1    Anders, R.J.2    MacIntyre, J.M.3
  • 27
    • 0030848602 scopus 로고    scopus 로고
    • Effects of controlled-onset extended-release verapamil on nocturnal blood pressure (dippers versus non-dippers). COER-Verapamil Study Group
    • White WB, Mehrotra DV, Black HR, Fakouhi TD. Effects of controlled-onset extended-release verapamil on nocturnal blood pressure (dippers versus non-dippers). COER-Verapamil Study Group. Am J Cardiol 1997; 80:469-474.
    • (1997) Am J Cardiol , vol.80 , pp. 469-474
    • White, W.B.1    Mehrotra, D.V.2    Black, H.R.3    Fakouhi, T.D.4
  • 28
    • 0035142781 scopus 로고    scopus 로고
    • A new chronotherapeutic oral drug absorption system for verapamil optimizes blood pressure control in the morning
    • Smith DH, Neutel JM, Weber MA. A new chronotherapeutic oral drug absorption system for verapamil optimizes blood pressure control in the morning. Am J Hypertens 2001; 14:14-19.
    • (2001) Am J Hypertens , vol.14 , pp. 14-19
    • Smith, D.H.1    Neutel, J.M.2    Weber, M.A.3
  • 29
    • 0037230462 scopus 로고    scopus 로고
    • Efficacy and safety of a once daily graded-rel ease diltiazem formulation in essential hypertension
    • Glasser SP, Neutel JM, Gana TJ, Albert KS. Efficacy and safety of a once daily graded-rel ease diltiazem formulation in essential hypertension. Am J Hypertens 2003; 16:51 -58.
    • (2003) Am J Hypertens , vol.16 , pp. 51-58
    • Glasser, S.P.1    Neutel, J.M.2    Gana, T.J.3    Albert, K.S.4
  • 30
    • 34249307910 scopus 로고    scopus 로고
    • Dose- and administration time-dependent effects of nifedipine gits on ambulatory blood pressure in hypertensive subjects
    • Hermida RC, Calvo C, Ayala DE, et al. Dose- and administration time-dependent effects of nifedipine gits on ambulatory blood pressure in hypertensive subjects. Chronobiol Int 2007; 24:471 -493.
    • (2007) Chronobiol Int , vol.24 , pp. 471-493
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 31
    • 3042745076 scopus 로고    scopus 로고
    • The antihypertensive efficacy and safety of a chronotherapeutic formulation of propranolol in patients with hypertension
    • Sica DA, Neutel JM, Weber MA, Manowitz N. The antihypertensive efficacy and safety of a chronotherapeutic formulation of propranolol in patients with hypertension. J Clin Hypertens (Greenwich) 2004; 6:231-241.
    • (2004) J Clin Hypertens (Greenwich) , vol.6 , pp. 231-241
    • Sica, D.A.1    Neutel, J.M.2    Weber, M.A.3    Manowitz, N.4
  • 32
    • 3543030417 scopus 로고    scopus 로고
    • Administration-time- dependent effects of doxazosin GITS on ambulatory blood pressure of hypertensive subjects
    • Hermida RC, Calvo C, Ayala DE, et al. Administration-time- dependent effects of doxazosin GITS on ambulatory blood pressure of hypertensive subjects. Chronobiol Int 2004; 21:277-296.
    • (2004) Chronobiol Int , vol.21 , pp. 277-296
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3
  • 33
    • 37349007842 scopus 로고    scopus 로고
    • Chronotherapy improves blood pressure control and reverts the nondipper pattern in patients with resistant hypertension
    • Hermida RC, Ayala DE, Fernandez JR, Calvo C. Chronotherapy improves blood pressure control and reverts the nondipper pattern in patients with resistant hypertension. Hypertension 2008; 51:69-76.
    • (2008) Hypertension , vol.51 , pp. 69-76
    • Hermida, R.C.1    Ayala, D.E.2    Fernandez, J.R.3    Calvo, C.4
  • 34
    • 33644651744 scopus 로고    scopus 로고
    • Effects of time of day of treatment on ambulatory blood pressure pattern of patients with resistant hypertension
    • Hermida RC, Ayala DE, Calvo C, et al. Effects of time of day of treatment on ambulatory blood pressure pattern of patients with resistant hypertension. Hypertension 2005; 46:1053-1059.
    • (2005) Hypertension , vol.46 , pp. 1053-1059
    • Hermida, R.C.1    Ayala, D.E.2    Calvo, C.3
  • 35
    • 36249003834 scopus 로고    scopus 로고
    • Changing the timing of antihyperten-sive therapy to reduce nocturnal blood pressure in CKD: An 8-week uncontrolled trial
    • Minutolo R, Gabbai FB, Borrelli S, et al. Changing the timing of antihyperten-sive therapy to reduce nocturnal blood pressure in CKD: an 8-week uncontrolled trial. Am J Kidney Dis 2007; 50:908-917.
    • (2007) Am J Kidney Dis , vol.50 , pp. 908-917
    • Minutolo, R.1    Gabbai, F.B.2    Borrelli, S.3
  • 36
    • 33644637086 scopus 로고    scopus 로고
    • Hermida RC, Calvo C, Ayala DE, Lopez JE. Decrease in urinary albumin excretion associated with the normalization of nocturnal blood pressure in hypertensive subjects. Hypertension 2005; 46:960-968.
    • Hermida RC, Calvo C, Ayala DE, Lopez JE. Decrease in urinary albumin excretion associated with the normalization of nocturnal blood pressure in hypertensive subjects. Hypertension 2005; 46:960-968.
  • 37
    • 66649092638 scopus 로고    scopus 로고
    • On behalf of the Japan Morning Surge-1 (JMS-1) study group. An alpha-adrenergic blocker titrated by self-measured blood pressure recordings lowered blood pressure and microalbuminuria in patients with morning hypertension:TheJapan Morning Surge-1 (JMS-1) Study
    • in press
    • Kario K, Matsui Y, Shibasaki S, et al. On behalf of the Japan Morning Surge-1 (JMS-1) study group. An alpha-adrenergic blocker titrated by self-measured blood pressure recordings lowered blood pressure and microalbuminuria in patients with morning hypertension:TheJapan Morning Surge-1 (JMS-1) Study. J Hypertens (in press).
    • J Hypertens
    • Kario, K.1    Matsui, Y.2    Shibasaki, S.3
  • 38
    • 18844379368 scopus 로고    scopus 로고
    • The bedtime administration of doxazosin controls morning hypertension and albuminuria in patients with type-2 diabetes: Evaluation using home-based blood pressure measurements
    • Kamoi K, IkarashiT.The bedtime administration of doxazosin controls morning hypertension and albuminuria in patients with type-2 diabetes: evaluation using home-based blood pressure measurements. Clin Exp Hypertens 2005; 27:369-376.
    • (2005) Clin Exp Hypertens , vol.27 , pp. 369-376
    • Kamoi, K.1    IkarashiT2
  • 39
    • 36749060465 scopus 로고    scopus 로고
    • Bedtime administration of cilnidipine controls morning hypertension
    • Ashizawa N, Seto S, Shibata Y, Yano K. Bedtime administration of cilnidipine controls morning hypertension. Int Heart J 2007; 48:597-603.
    • (2007) Int Heart J , vol.48 , pp. 597-603
    • Ashizawa, N.1    Seto, S.2    Shibata, Y.3    Yano, K.4
  • 40
    • 20144365882 scopus 로고    scopus 로고
    • Regression of carotid atherosclerosis by control of morning blood pressure peak in newly diagnosed hypertensive patients
    • Marfella R, Siniscalchi M, Nappo F, et al. Regression of carotid atherosclerosis by control of morning blood pressure peak in newly diagnosed hypertensive patients. Am J Hypertens 2005; 18:308-318.
    • (2005) Am J Hypertens , vol.18 , pp. 308-318
    • Marfella, R.1    Siniscalchi, M.2    Nappo, F.3
  • 41
    • 0036166249 scopus 로고    scopus 로고
    • Blood pressure reduction in the morning yields beneficial effects on progression of chronic renal insufficiency with regression of left ventricular hypertrophy
    • Suzuki H, Moriwaki K, Nakamoto H. Blood pressure reduction in the morning yields beneficial effects on progression of chronic renal insufficiency with regression of left ventricular hypertrophy. Clin Exp Hypertens 2002; 24:51 -63.
    • (2002) Clin Exp Hypertens , vol.24 , pp. 51-63
    • Suzuki, H.1    Moriwaki, K.2    Nakamoto, H.3
  • 42
    • 37849006805 scopus 로고    scopus 로고
    • Add-on effect of bedtime dosing of the alpha(1)-adrenergic receptor antagonist doxazosin on morning hypertension and left ventricular hypertrophy in patients undergoing long-term amlodipine monotherapy
    • Ikeda T, Gomi T, Shibuya Y, et al. Add-on effect of bedtime dosing of the alpha(1)-adrenergic receptor antagonist doxazosin on morning hypertension and left ventricular hypertrophy in patients undergoing long-term amlodipine monotherapy. Hypertens Res 2007; 30:1097-1105.
    • (2007) Hypertens Res , vol.30 , pp. 1097-1105
    • Ikeda, T.1    Gomi, T.2    Shibuya, Y.3
  • 43
    • 0037851836 scopus 로고    scopus 로고
    • CONVINCE Research Group. Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial
    • Black HR, Elliott WJ, Grandits G, et al., CONVINCE Research Group. Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial. JAMA 2003; 289:2073-2082.
    • (2003) JAMA , vol.289 , pp. 2073-2082
    • Black, H.R.1    Elliott, W.J.2    Grandits, G.3
  • 44
    • 0343487983 scopus 로고    scopus 로고
    • Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators
    • Staessen JA, Fagard R, Thijs L, et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet 1997; 350:757-764.
    • (1997) Lancet , vol.350 , pp. 757-764
    • Staessen, J.A.1    Fagard, R.2    Thijs, L.3
  • 45
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342:145-153.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3
  • 46
    • 17044440752 scopus 로고    scopus 로고
    • Comparative effects of ramipril on ambulatory and office blood pressures: A HOPE Substudy
    • Svensson P, de Faire U, Sleight P, et al. Comparative effects of ramipril on ambulatory and office blood pressures: a HOPE Substudy. Hypertension 2001; 38:E28-E32.
    • (2001) Hypertension , vol.38
    • Svensson, P.1    de Faire, U.2    Sleight, P.3
  • 47
    • 34547889461 scopus 로고    scopus 로고
    • Ambulatory blood pressure monitoring in the prediction of cardiovascular events and effects of chronotherapy: Rationale and design of the MAPEC study
    • Hermida RC. Ambulatory blood pressure monitoring in the prediction of cardiovascular events and effects of chronotherapy: rationale and design of the MAPEC study. Chronobiol Int 2007; 24:749-775.
    • (2007) Chronobiol Int , vol.24 , pp. 749-775
    • Hermida, R.C.1
  • 48
    • 34247565969 scopus 로고    scopus 로고
    • Prediction of cardiovascular events by ambulatory blood pressure and effects of chronotherapy: The MAPEC study [abstract]
    • Hermida RC, Calvo C, Ayala DE, et al. Prediction of cardiovascular events by ambulatory blood pressure and effects of chronotherapy: The MAPEC study [abstract]. J Hypertens 2006; 24 (Suppl 4):S180.
    • (2006) J Hypertens , vol.24 , Issue.SUPPL. 4
    • Hermida, R.C.1    Calvo, C.2    Ayala, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.