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Volumn 11, Issue 1, 2009, Pages 33-37

Pediatric clinical pharmacology studies in Chagas disease: Focus on Argentina

Author keywords

Chagas' disease; Children; Pharmacology

Indexed keywords

BENZNIDAZOLE; NIFURTIMOX;

EID: 58149350101     PISSN: 11745878     EISSN: None     Source Type: Journal    
DOI: 10.2165/0148581-200911010-00012     Document Type: Conference Paper
Times cited : (25)

References (60)
  • 1
    • 0142227145 scopus 로고    scopus 로고
    • Specific chemotherapy of Chagas disease: Controversies and advances
    • Urbina JA, Docampo R. Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasitol 2003; 19 (11): 495-501
    • (2003) Trends Parasitol , vol.19 , Issue.11 , pp. 495-501
    • Urbina, J.A.1    Docampo, R.2
  • 2
    • 36348949834 scopus 로고    scopus 로고
    • Epidemiology of Chagas disease in non-endemic countries: The role of international migration
    • Schmunis GA. Epidemiology of Chagas disease in non-endemic countries: the role of international migration. Mem Inst Oswaldo Cruz 2007; 102 Suppl. 1: 75-85
    • (2007) Mem Inst Oswaldo Cruz , vol.102 , Issue.SUPPL. 1 , pp. 75-85
    • Schmunis, G.A.1
  • 3
    • 84931401270 scopus 로고    scopus 로고
    • WHO Expert Committee on the Control of Chagas Disease, World Health Organization, Geneva: World Health Organization
    • WHO Expert Committee on the Control of Chagas Disease, World Health Organization. Control of Chagas disease: Second report of the WHO Expert Committee. 905ed. Geneva: World Health Organization, 2002
    • (2002) Control of Chagas disease: Second report of the WHO Expert Committee
  • 4
    • 0042705476 scopus 로고    scopus 로고
    • Risk of Chagas disease through transfusions in the Americans
    • in Spanish
    • Schmunis GA. Risk of Chagas disease through transfusions in the Americans [in Spanish]. Medicina (B Aires) 1999; 59 Suppl. 2: 125-34
    • (1999) Medicina (B Aires) , vol.59 , Issue.SUPPL. 2 , pp. 125-134
    • Schmunis, G.A.1
  • 5
    • 0029094286 scopus 로고
    • Congenital Chagas' disease: Diagnostic and clinical aspects
    • Freilij H, Altcheh J. Congenital Chagas' disease: diagnostic and clinical aspects. Clin Infect Dis 1995; 21 (3): 551-5
    • (1995) Clin Infect Dis , vol.21 , Issue.3 , pp. 551-555
    • Freilij, H.1    Altcheh, J.2
  • 6
    • 0037240180 scopus 로고    scopus 로고
    • Congenital transmission of Trypanosoma cruzi infection in Argentina
    • Gurtler RE, Segura EL, Cohen JE. Congenital transmission of Trypanosoma cruzi infection in Argentina. Emerg Infect Dis 2003; 9 (1): 29-32
    • (2003) Emerg Infect Dis , vol.9 , Issue.1 , pp. 29-32
    • Gurtler, R.E.1    Segura, E.L.2    Cohen, J.E.3
  • 9
    • 0037963656 scopus 로고    scopus 로고
    • Nitroheterocyclic drugs with broad spectrum activity
    • Raether W, Hanel H. Nitroheterocyclic drugs with broad spectrum activity. Parasitol Res 2003; 90 Suppl. 1: S19-39
    • (2003) Parasitol Res , vol.90 , Issue.SUPPL. 1
    • Raether, W.1    Hanel, H.2
  • 10
    • 0020455681 scopus 로고
    • Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations
    • Moreno SN, Docampo R, Mason RP, et al. Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations. Arch Biochem Biophys 1982; 218 (2): 585-91
    • (1982) Arch Biochem Biophys , vol.218 , Issue.2 , pp. 585-591
    • Moreno, S.N.1    Docampo, R.2    Mason, R.P.3
  • 11
    • 0025166484 scopus 로고
    • Sensitivity of parasites to free radical damage by antiparasitic drugs
    • Docampo R. Sensitivity of parasites to free radical damage by antiparasitic drugs. Chem Biol Interact 1990; 73 (1): 1-27
    • (1990) Chem Biol Interact , vol.73 , Issue.1 , pp. 1-27
    • Docampo, R.1
  • 12
    • 0026666065 scopus 로고
    • Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives
    • Lau AH, Lam NP, Piscitelli SC, et al. Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives. Clin Pharmacokinet 1992; 23 (5): 328-64
    • (1992) Clin Pharmacokinet , vol.23 , Issue.5 , pp. 328-364
    • Lau, A.H.1    Lam, N.P.2    Piscitelli, S.C.3
  • 13
    • 0018728563 scopus 로고
    • Single-dose pharmacokinetics of the trypanosomicide benznidazole in man
    • Raaflaub J, Ziegler WH. Single-dose pharmacokinetics of the trypanosomicide benznidazole in man. Arzneimittelforschung 1979; 29 (10): 1611-4
    • (1979) Arzneimittelforschung , vol.29 , Issue.10 , pp. 1611-1614
    • Raaflaub, J.1    Ziegler, W.H.2
  • 14
    • 0019203048 scopus 로고
    • Multiple-dose kinetics of the trypanosomicide benznidazole in man
    • Raaflaub J. Multiple-dose kinetics of the trypanosomicide benznidazole in man. Arzneimittelforschung 1980; 30 (12): 2192-4
    • (1980) Arzneimittelforschung , vol.30 , Issue.12 , pp. 2192-2194
    • Raaflaub, J.1
  • 15
    • 0019180499 scopus 로고
    • Difference of effective antitrypanosomal dosages of benznidazole in mice and man: Chemotherapeutic and pharmacokinetic results
    • Richle RW, Raaflaub J. Difference of effective antitrypanosomal dosages of benznidazole in mice and man: chemotherapeutic and pharmacokinetic results. Acta Trop 1980; 37 (3): 257-61
    • (1980) Acta Trop , vol.37 , Issue.3 , pp. 257-261
    • Richle, R.W.1    Raaflaub, J.2
  • 16
    • 0021237527 scopus 로고
    • Preclinical pharmacokinetics of benznidazole
    • Workman P, White RA, Walton MI, et al. Preclinical pharmacokinetics of benznidazole. Br J Cancer 1984; 50 (3): 291-303
    • (1984) Br J Cancer , vol.50 , Issue.3 , pp. 291-303
    • Workman, P.1    White, R.A.2    Walton, M.I.3
  • 17
    • 0022620193 scopus 로고
    • Altered pharmacokinetics in the mechanism of chemosensitization: Effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards
    • Lee FY, Workman P. Altered pharmacokinetics in the mechanism of chemosensitization: effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards. Cancer Chemother Pharmacol 1986; 17 (1): 30-7
    • (1986) Cancer Chemother Pharmacol , vol.17 , Issue.1 , pp. 30-37
    • Lee, F.Y.1    Workman, P.2
  • 18
    • 0022570743 scopus 로고
    • Benznidazole: Nitroreduction and inhibition of cytochrome P-450 in chemosensitization of tumour response to cytotoxic drugs
    • Workman P, Walton MI, Lee FY. Benznidazole: nitroreduction and inhibition of cytochrome P-450 in chemosensitization of tumour response to cytotoxic drugs. Biochem Pharmacol 1986; 35 (1): 117-9
    • (1986) Biochem Pharmacol , vol.35 , Issue.1 , pp. 117-119
    • Workman, P.1    Walton, M.I.2    Lee, F.Y.3
  • 19
    • 0023238102 scopus 로고
    • Misonidazole and benznidazole inhibit hydroxylation of CCNU by mouse liver microsomal cytochrome P-450 in vitro
    • Lee FY, Workman P, Cheeseman KH. Misonidazole and benznidazole inhibit hydroxylation of CCNU by mouse liver microsomal cytochrome P-450 in vitro. Biochem Pharmacol 1987; 36 (8): 1349-55
    • (1987) Biochem Pharmacol , vol.36 , Issue.8 , pp. 1349-1355
    • Lee, F.Y.1    Workman, P.2    Cheeseman, K.H.3
  • 20
    • 0023153554 scopus 로고
    • Nitroimidazole bioreductive metabolism: Quantitation and characterisation of mouse tissue benznidazole nitroreductases in vivo and in vitro
    • Walton MI, Workman P. Nitroimidazole bioreductive metabolism: quantitation and characterisation of mouse tissue benznidazole nitroreductases in vivo and in vitro. Biochem Pharmacol 1987; 36 (6): 887-96
    • (1987) Biochem Pharmacol , vol.36 , Issue.6 , pp. 887-896
    • Walton, M.I.1    Workman, P.2
  • 21
    • 0026748313 scopus 로고
    • The pharmacokinetics of nifurtimox in chronic renal failure
    • Gonzalez-Martin G, Thambo S, Paulos C, et al. The pharmacokinetics of nifurtimox in chronic renal failure. Eur J Clin Pharmacol 1992; 42 (6): 671-3
    • (1992) Eur J Clin Pharmacol , vol.42 , Issue.6 , pp. 671-673
    • Gonzalez-Martin, G.1    Thambo, S.2    Paulos, C.3
  • 22
    • 0024325258 scopus 로고
    • Pharmacokinetics of a nitrofuran compound, nifurtimox, in healthy volunteers
    • Paulos C, Paredes J, Vasquez I, et al. Pharmacokinetics of a nitrofuran compound, nifurtimox, in healthy volunteers. Int J Clin Pharmacol Ther Toxicol 1989; 27 (9): 454-7
    • (1989) Int J Clin Pharmacol Ther Toxicol , vol.27 , Issue.9 , pp. 454-457
    • Paulos, C.1    Paredes, J.2    Vasquez, I.3
  • 23
    • 0015390487 scopus 로고
    • Quantitative determination of nifurtimox in body fluids of rat, dog and man
    • Medenwald H, Brandau K, Schlossmann K. Quantitative determination of nifurtimox in body fluids of rat, dog and man. Arzneimittelforschung 1972; 22 (9): 1613-7
    • (1972) Arzneimittelforschung , vol.22 , Issue.9 , pp. 1613-1617
    • Medenwald, H.1    Brandau, K.2    Schlossmann, K.3
  • 24
    • 0015391624 scopus 로고
    • Investigations on the pharmacokinetics of nifurtimox- 35 S in the rat and dog
    • Duhm B, Maul W, Medenwald H, et al. Investigations on the pharmacokinetics of nifurtimox- 35 S in the rat and dog. Arzneimittelforschung 1972; 22 (9): 1617-24
    • (1972) Arzneimittelforschung , vol.22 , Issue.9 , pp. 1617-1624
    • Duhm, B.1    Maul, W.2    Medenwald, H.3
  • 25
    • 0021166199 scopus 로고
    • Studies on nifurtimox nitroreductase activity in liver and other rat tissues
    • Masana M, de Toranzo EG, Castro JA. Studies on nifurtimox nitroreductase activity in liver and other rat tissues. Arch Int Pharmacodyn Ther 1984; 270 (1): 4-10
    • (1984) Arch Int Pharmacodyn Ther , vol.270 , Issue.1 , pp. 4-10
    • Masana, M.1    de Toranzo, E.G.2    Castro, J.A.3
  • 26
    • 10544244169 scopus 로고    scopus 로고
    • Randomised trial of efficacy of benznidazole in treatment of early Trypanosoma cruzi infection
    • de Andrade AL, Zicker F, de Oliveira RM, et al. Randomised trial of efficacy of benznidazole in treatment of early Trypanosoma cruzi infection. Lancet 1996; 348 (9039): 1407-13
    • (1996) Lancet , vol.348 , Issue.9039 , pp. 1407-1413
    • de Andrade, A.L.1    Zicker, F.2    de Oliveira, R.M.3
  • 27
    • 0005083961 scopus 로고    scopus 로고
    • Sosa ES, Segura EL. Treatment of Trypanosoma cruzi infection in the indeterminate phase: experience and current guidelines in Argentina [in Spanish]. Medization. cina (B Aires) 1999; 59 Suppl. 2: 166-70
    • Sosa ES, Segura EL. Treatment of Trypanosoma cruzi infection in the indeterminate phase: experience and current guidelines in Argentina [in Spanish]. Medization. cina (B Aires) 1999; 59 Suppl. 2: 166-70
  • 28
    • 33749123918 scopus 로고    scopus 로고
    • Congenital Chagas disease: Experience in the Hospital de Ninos, Ricardo Gutierrez, Buenos Aires, Argentina
    • in Spanish
    • Altcheh J, Biancardi M, Lapena A, et al. Congenital Chagas disease: experience in the Hospital de Ninos, Ricardo Gutierrez, Buenos Aires, Argentina [in Spanish]. Rev Soc Bras Med Trop 2005; 38 Suppl. 2: 41-5
    • (2005) Rev Soc Bras Med Trop , vol.38 , Issue.SUPPL. 2 , pp. 41-45
    • Altcheh, J.1    Biancardi, M.2    Lapena, A.3
  • 29
    • 3543087283 scopus 로고    scopus 로고
    • Efficacy of chemotherapy with benznidazole in children in the indeterminate phase of Chagas' disease
    • Sosa ES, Segura EL, Ruiz AM, et al. Efficacy of chemotherapy with benznidazole in children in the indeterminate phase of Chagas' disease. Am J Trop Med Hyg 1998; 59 (4): 526-9
    • (1998) Am J Trop Med Hyg , vol.59 , Issue.4 , pp. 526-529
    • Sosa, E.S.1    Segura, E.L.2    Ruiz, A.M.3
  • 30
    • 0022384591 scopus 로고
    • Treatment of Chagas' disease with nifurtimox during the first months of life
    • in Spanish
    • Moya PR, Paolasso RD, Blanco S, et al. Treatment of Chagas' disease with nifurtimox during the first months of life [in Spanish]. Medicina (B Aires) 1985; 45 (5): 553-8
    • (1985) Medicina (B Aires) , vol.45 , Issue.5 , pp. 553-558
    • Moya, P.R.1    Paolasso, R.D.2    Blanco, S.3
  • 31
    • 0026785169 scopus 로고
    • Polymerase chain reaction-based detection of Trypanosoma cruzi DNA in serum
    • Russomando G, Figueredo A, Almiron M, et al. Polymerase chain reaction-based detection of Trypanosoma cruzi DNA in serum. J Clin Microbiol 1992; 30 (11): 2864-8
    • (1992) J Clin Microbiol , vol.30 , Issue.11 , pp. 2864-2868
    • Russomando, G.1    Figueredo, A.2    Almiron, M.3
  • 32
    • 4644223386 scopus 로고    scopus 로고
    • Longitudinal study and specific chemotherapy in children with chronic Chagas' disease, residing in a low endemicity area of Argentina
    • in Portugese
    • Streiger ML, del Barco ML, Fabbro DL, et al. Longitudinal study and specific chemotherapy in children with chronic Chagas' disease, residing in a low endemicity area of Argentina [in Portugese]. Rev Soc Bras Med Trop 2004; 37 (5): 365-75
    • (2004) Rev Soc Bras Med Trop , vol.37 , Issue.5 , pp. 365-375
    • Streiger, M.L.1    del Barco, M.L.2    Fabbro, D.L.3
  • 33
    • 0029005756 scopus 로고
    • Congenital Chagas disease in the city of Santa Fe. Diagnosis and treatment
    • in Spanish
    • Streiger M, Fabbro D, del Barco M, et al. Congenital Chagas disease in the city of Santa Fe. Diagnosis and treatment [in Spanish]. Medicina (B Aires) 1995; 55 (2): 125-32
    • (1995) Medicina (B Aires) , vol.55 , Issue.2 , pp. 125-132
    • Streiger, M.1    Fabbro, D.2    del Barco, M.3
  • 34
    • 0037248029 scopus 로고    scopus 로고
    • Anti-F2/3 antibodies as cure marker in children with congenital Trypanosoma cruzi infection
    • in Spanish
    • Altcheh J, Corral R, Biancardi MA, et al. Anti-F2/3 antibodies as cure marker in children with congenital Trypanosoma cruzi infection [in Spanish]. Medicina (B Aires) 2003; 63 (1): 37-40
    • (2003) Medicina (B Aires) , vol.63 , Issue.1 , pp. 37-40
    • Altcheh, J.1    Corral, R.2    Biancardi, M.A.3
  • 35
    • 33750503607 scopus 로고    scopus 로고
    • Etiological treatment in patients infected by Trypanosoma cruzi: Experiences in Argentina
    • Sosa-Estani S, Segura EL. Etiological treatment in patients infected by Trypanosoma cruzi: experiences in Argentina. Curr Opin Infect Dis 2006; 19 (6): 583-7
    • (2006) Curr Opin Infect Dis , vol.19 , Issue.6 , pp. 583-587
    • Sosa-Estani, S.1    Segura, E.L.2
  • 36
    • 0033252802 scopus 로고    scopus 로고
    • Treatment of Trypanosoma cruzi infection in the undetermined phase: Experience and current guidelines of treatment in Argentina
    • Sosa ES, Segura EL. Treatment of Trypanosoma cruzi infection in the undetermined phase: experience and current guidelines of treatment in Argentina. Mem Inst Oswaldo Cruz 1999; 94 Suppl. 1: 363-5
    • (1999) Mem Inst Oswaldo Cruz , vol.94 , Issue.SUPPL. 1 , pp. 363-365
    • Sosa, E.S.1    Segura, E.L.2
  • 37
    • 0141852795 scopus 로고    scopus 로고
    • Aetiological treatment of congenital Chagas' disease diagnosed and monitored by the polymerase chain reaction
    • Schijman AG, Altcheh J, Burgos JM, et al. Aetiological treatment of congenital Chagas' disease diagnosed and monitored by the polymerase chain reaction. J Antimicrob Chemother 2003; 52 (3): 441-9
    • (2003) J Antimicrob Chemother , vol.52 , Issue.3 , pp. 441-449
    • Schijman, A.G.1    Altcheh, J.2    Burgos, J.M.3
  • 38
    • 0027955005 scopus 로고
    • Treatment of chronic Chagas' disease with benznidazole: Clinical and serologic evolution of patients with long-term follow-up
    • Viotti R, Vigliano C, Armenti H, et al. Treatment of chronic Chagas' disease with benznidazole: clinical and serologic evolution of patients with long-term follow-up. Am. Heart J 1994; 127 (1): 151-62
    • (1994) Am. Heart J , vol.127 , Issue.1 , pp. 151-162
    • Viotti, R.1    Vigliano, C.2    Armenti, H.3
  • 39
    • 34248531970 scopus 로고    scopus 로고
    • Trypanocide treatment among adults with chronic Chagas disease living in Santa Fe city (Argentina), over a mean follow-up of 21 years: Parasitological, serological and clinical evolution
    • Fabbro DL, Streiger ML, Arias ED, et al. Trypanocide treatment among adults with chronic Chagas disease living in Santa Fe city (Argentina), over a mean follow-up of 21 years: parasitological, serological and clinical evolution. Rev Soc Bras Med Trop 2007; 40 (1): 1-10
    • (2007) Rev Soc Bras Med Trop , vol.40 , Issue.1 , pp. 1-10
    • Fabbro, D.L.1    Streiger, M.L.2    Arias, E.D.3
  • 40
    • 17144468784 scopus 로고    scopus 로고
    • Evolutive behavior towards cardiomyopathy of treated (nifurtimox or benznidazole) and untreated chronic chagasic patients
    • Fabbro DS, Arias E, Streiger M, et al. Evolutive behavior towards cardiomyopathy of treated (nifurtimox or benznidazole) and untreated chronic chagasic patients. Rev Inst Med Trop Sao Paulo 2000; 42 (2): 99-109
    • (2000) Rev Inst Med Trop Sao Paulo , vol.42 , Issue.2 , pp. 99-109
    • Fabbro, D.S.1    Arias, E.2    Streiger, M.3
  • 41
    • 33646847271 scopus 로고    scopus 로고
    • Long-term cardiac outcomes of treating chronic Chagas disease with benznidazole versus no treatment: A non-randomized trial
    • Viotti R, Vigliano C, Lococo B, et al. Long-term cardiac outcomes of treating chronic Chagas disease with benznidazole versus no treatment: a non-randomized trial. Ann Intern Med 2006; 144 (10): 724-34
    • (2006) Ann Intern Med , vol.144 , Issue.10 , pp. 724-734
    • Viotti, R.1    Vigliano, C.2    Lococo, B.3
  • 42
    • 45549100534 scopus 로고    scopus 로고
    • Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: The BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT)
    • Marin-Neto JA, Rassi Jr A, Morillo CA, et al. Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT). Am Heart J 2008; 156 (1): 37-43
    • (2008) Am Heart J , vol.156 , Issue.1 , pp. 37-43
    • Marin-Neto, J.A.1    Rassi Jr, A.2    Morillo, C.A.3
  • 43
    • 0032887329 scopus 로고    scopus 로고
    • An update on the therapeutic orphan
    • Wilson JT. An update on the therapeutic orphan. Pediatrics 1999; 104 (3 Pt 2): 585-90
    • (1999) Pediatrics , vol.104 , Issue.3 PART 2 , pp. 585-590
    • Wilson, J.T.1
  • 44
    • 0032887152 scopus 로고    scopus 로고
    • Lack of pediatric drug formulations
    • Nahata MC. Lack of pediatric drug formulations. Pediatrics 1999; 104 (3 Pt 2): 607-9
    • (1999) Pediatrics , vol.104 , Issue.3 PART 2 , pp. 607-609
    • Nahata, M.C.1
  • 45
    • 0032885653 scopus 로고    scopus 로고
    • The therapeutic orphan: 30 years later. Proceedings of a joint conference of the Pediatric Pharmacology Research Unit Network, the European Society of Developmental Pharmacology, and the National Institute of Child Health and Human Development. Washington DC, USA, May 2, 1997. Pediatrics 1999; 104 (3 Pt 2): 581-645
    • The therapeutic orphan: 30 years later. Proceedings of a joint conference of the Pediatric Pharmacology Research Unit Network, the European Society of Developmental Pharmacology, and the National Institute of Child Health and Human Development. Washington DC, USA, May 2, 1997. Pediatrics 1999; 104 (3 Pt 2): 581-645
  • 46
    • 58149341524 scopus 로고
    • Polineuropatia periférica induzida por benzonidazol no tratamento da doença de Chagas. 129 [letter].
    • Faria CR, Souza SEM, Rassi A. Polineuropatia periférica induzida por benzonidazol no tratamento da doença de Chagas. 129 [letter]. Arq Neuropsiq 1986; 44 (2): 125
    • (1986) Arq Neuropsiq , vol.44 , Issue.2 , pp. 125
    • Faria, C.R.1    Souza, S.E.M.2    Rassi, A.3
  • 47
    • 0342762072 scopus 로고    scopus 로고
    • Experimental benznidazole encephalopathy: I. Clinical-neurological alterations
    • Flores-Vieira CL, Barreira AA. Experimental benznidazole encephalopathy: I. Clinical-neurological alterations. J Neurol Sci 1997; 150 (1): 3-11
    • (1997) J Neurol Sci , vol.150 , Issue.1 , pp. 3-11
    • Flores-Vieira, C.L.1    Barreira, A.A.2
  • 48
    • 0030795539 scopus 로고    scopus 로고
    • Experimental benznidazole encephalopathy: II. Electroencephalographic and morphological alterations
    • Flores-Vieira CL, Chimelli L, Franca Fernandes RM, et al. Experimental benznidazole encephalopathy: II. Electroencephalographic and morphological alterations. J Neurol Sci 1997; 150 (1): 13-25
    • (1997) J Neurol Sci , vol.150 , Issue.1 , pp. 13-25
    • Flores-Vieira, C.L.1    Chimelli, L.2    Franca Fernandes, R.M.3
  • 49
    • 58149356159 scopus 로고    scopus 로고
    • WHO Expert Committee on the Control of Chagas Disease, World Health Organization, 2005. 905ed. Geneva: World Health Organization, 2005 [online, Available from URL:, Accessed Aug 28
    • WHO Expert Committee on the Control of Chagas Disease, World Health Organization. Report of the WHO Expert Committee on the Control of Chagas Disease, 2005. 905ed. Geneva: World Health Organization, 2005 [online]. Available from URL: http://www.who.int/tdr/publications/publications/pdf/ swg_chagas.pdf [Accessed 2008 Aug 28]
    • (2008) Report of the WHO Expert Committee on the Control of Chagas Disease
  • 50
    • 0017688679 scopus 로고
    • Estimation of population characteristics of pharmacokinetic parameters from routine clinical data
    • Sheiner LB, Rosenberg B, Marathe VV. Estimation of population characteristics of pharmacokinetic parameters from routine clinical data. J Pharmacokinet Bioto, pharm 1977; 5 (5): 445-79
    • (1977) J Pharmacokinet Bioto, pharm , vol.5 , Issue.5 , pp. 445-479
    • Sheiner, L.B.1    Rosenberg, B.2    Marathe, V.V.3
  • 51
    • 0019504571 scopus 로고
    • A standard approach to compiling clinical pharmacokinetic data
    • Sheiner LB, Benet LZ, Pagliaro LA. A standard approach to compiling clinical pharmacokinetic data. J Pharmacokinet Biopharm 1981; 9 (1): 59-127
    • (1981) J Pharmacokinet Biopharm , vol.9 , Issue.1 , pp. 59-127
    • Sheiner, L.B.1    Benet, L.Z.2    Pagliaro, L.A.3
  • 52
    • 0021269554 scopus 로고
    • The population approach to pharmacokinetic data analysis: Rationale and standard data analysis methods
    • Sheiner LB. The population approach to pharmacokinetic data analysis: rationale and standard data analysis methods. Drug Metab Rev 1984; 15 (1-2): 153-71
    • (1984) Drug Metab Rev , vol.15 , Issue.1-2 , pp. 153-171
    • Sheiner, L.B.1
  • 54
    • 28444445596 scopus 로고    scopus 로고
    • Some considerations on the design of population pharmacokinetic studies
    • Duffull S, Waterhouse T, Eccleston J. Some considerations on the design of population pharmacokinetic studies. J Pharmacokinet Pharmacodyn 2005; 32 (3-4): 441-57
    • (2005) J Pharmacokinet Pharmacodyn , vol.32 , Issue.3-4 , pp. 441-457
    • Duffull, S.1    Waterhouse, T.2    Eccleston, J.3
  • 55
    • 0035174532 scopus 로고    scopus 로고
    • Design of clinical pharmacology trials
    • Duffull SB. Design of clinical pharmacology trials. Clin Exp Pharmacol Physiol 2001; 28 (11): 905-12
    • (2001) Clin Exp Pharmacol Physiol , vol.28 , Issue.11 , pp. 905-912
    • Duffull, S.B.1
  • 56
    • 30444448534 scopus 로고    scopus 로고
    • Meibohm B, Laer S, Panetta JC, et al. Population pharmacokinetic studies in pediatrics: issues in design and analysis. AAPS J 2005; 7 (2): E475-87
    • Meibohm B, Laer S, Panetta JC, et al. Population pharmacokinetic studies in pediatrics: issues in design and analysis. AAPS J 2005; 7 (2): E475-87
  • 57
    • 30544448391 scopus 로고    scopus 로고
    • Roy A, Ette EI. A pragmatic approach to the design of population pharmacokinetic studies. AAPS J 2005; 7 (2): E408-20
    • Roy A, Ette EI. A pragmatic approach to the design of population pharmacokinetic studies. AAPS J 2005; 7 (2): E408-20
  • 58
    • 0019289897 scopus 로고
    • Evaluation of methods for estimating population pharmacokinetics parameters: I. Michaelis-Menten model: routine clinical pharmacokinetic data
    • Sheiner LB, Beal SL. Evaluation of methods for estimating population pharmacokinetics parameters: I. Michaelis-Menten model: routine clinical pharmacokinetic data. J Pharmacokinet Biopharm 1980; 8 (6): 553-71
    • (1980) J Pharmacokinet Biopharm , vol.8 , Issue.6 , pp. 553-571
    • Sheiner, L.B.1    Beal, S.L.2
  • 59
    • 58149362087 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER)
    • online, Available from URL:, Accessed 2008 Aug 28
    • US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER). Guidance for industry: population pharmacokinetics. 1999 [online]. Available from URL: http://www.fda.gov/CDER/guidance/1852fnl.pdf. [Accessed 2008 Aug 28]
    • (1999) Guidance for industry: Population pharmacokinetics
  • 60
    • 58149341090 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 Nov 18
    • Clinicaltrials.gov registry number NCT00699387 [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2008 Nov 18]
    • Clinicaltrials.gov registry number NCT00699387


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