NTP report on the toxicology studies of aspartame (CAS No. 22839-47-0) in genetically modified (FVB Tg.AC hemizygous) and B6.129-Cdkn2atm1Rdp (N2) deficient mice and carcinogenicity studies of aspartame in genetically modified [B6.129-Trp53tm1Brd (N5) haploinsufficient] mice (feed studies).

National Toxicology Program genetically modified model report

Volumn , Issue 1, 2005, Pages 1-222

  Bucher, J R ^a   Bristol, D W ^a   French, J E ^a   Hailey, J R ^a   Haseman, J K ^a   Herbert, R A ^a,a   Malarkey, D E ^a   Maronpot, R R ^a   Peckham, J C ^a   Roycroft, J H ^a   Smith, C S ^a   Travlos, G S ^a   Vallant, M K ^a   Witt, K L ^a   Wenk, M L ^a   Lanning, L L ^a   Hardisty, J F ^a   Shackelford, C C ^a   Brecher, S ^a   Long, P ^a   Dixon, D ^a   Flake, G P ^a   Little, P B ^a   Nyska, A ^a   Crockett, P W ^a   Betz, L J ^a   McGowan, K P ^a   Scott, J T ^a   Gunnels, S R ^a   Carver, P H ^a   Coker, K K ^a   Hall, B F ^a   Harper, L M ^a   Rathman, E S ^a   Serbus, D C ^a   Willis, R A ^a   more..

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTAME; CDKN2A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PROTEIN P53; SWEETENING AGENT; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CARCINOGEN TESTING; FEMALE; GENETICS; MALE; MOUSE; ONCOGENE RAS; TRANSGENIC MOUSE;

ANIMALS; ASPARTAME; CARCINOGENICITY TESTS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; GENES, RAS; MALE; MICE; MICE, TRANSGENIC; SWEETENING AGENTS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 58149337399     PISSN: None     EISSN: 15565246     Source Type: Journal    
DOI: None     Document Type: Article

References (0)