Focal fluid-attenuated inversion recovery hyperintensity within acute diffusion-weighted imaging lesions is associated with symptomatic intracerebral hemorrhage after thrombolysis

Stroke

Volumn 39, Issue 12, 2008, Pages 3424-3426

  Cho, A Hyun ^a,b   Kim, Jong S ^a   Kim, Sang Joon ^a   Yun, Sung Cheol ^a   Choi, Choong Gon ^a   Kim, Hyoung Ryoul ^c   Kwon, Sun U ^a   Lee, Deok Hee ^a   Kim, Eun Kyung ^a   Suh, Dae Chul ^a   Kang, Dong Wha ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Department of Neurology ^*

^c The Catholic University of Korea   (South Korea)

Author keywords

Acute stroke; Intracerebral hemorrhage; MRI; Thrombolysis

Indexed keywords

ADULT; ARTICLE; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SYMPTOMATIC INTRACEREBRAL HEMORRHAGE; ACUTE DISEASE; AGED; BRAIN ISCHEMIA; CHEMICALLY INDUCED DISORDER; DISEASE PREDISPOSITION; DRUG COMBINATION; FIBRINOLYTIC THERAPY; HOSPITALIZATION; INTRAARTERIAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; PATHOLOGY; PATIENT SELECTION; RETROSPECTIVE STUDY; RISK;

FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

ACUTE DISEASE; AGED; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; DIFFUSION MAGNETIC RESONANCE IMAGING; DISEASE SUSCEPTIBILITY; DRUG THERAPY, COMBINATION; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INFUSIONS, INTRA-ARTERIAL; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PATIENT SELECTION; RETROSPECTIVE STUDIES; RISK; SEVERITY OF ILLNESS INDEX; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 58149330238     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.516740     Document Type: Article

References (8)

1. Schellinger PD, Jansen O, Fiebach JB, Pohlers O, Ryssel H, Heiland S, Steiner T, Hacke W, Sartor K. Feasibility and practicality of MR imaging of stroke in the management of hyperacute cerebral ischemia. AJNR Am J Neuroradiol. 2000;21:1184-1189.
2. Kang DW, Chalela JA, Dunn W, Warach S. MRI screening before standard tissue plasminogen activator therapy is feasible and safe. Stroke. 2005;36: 1939-1943.
3. Kohrmann M, Juttler E, Fiebach JB, Huttner HB, Siebert S, Schwark C, Ringleb PA, Schellinger PD, Hacke W. MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study. Lancet Neurol. 2006;5:661-667.
4. Cho AH, Sohn SI, Han MK, Lee DH, Kim JS, Choi CG, Sohn CH, Kwon SU, Suh DC, Kim SJ, Bae HJ, Kang DW. Safety and efficacy of MRI-based thrombolysis in unclear-onset stroke: a preliminary report. Cerebrovasc Dis. 2008;25:572-579.
5. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA stroke study group. N Engl J Med. 1995;333:1581-1587.
6. Berger C, Fiorelli M, Steiner T, Schabitz WR, Bozzao L, Bluhmki E, Hacke W, von Kummer R. Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic? Stroke. 2001;32:1330-1335.
7. Sauerbrei W, Schumacher M. A bootstrap resampling procedure for model building: application to the cox regression model. Stat Med. 1992;11: 2093-2109.
8. Schellinger PD, Thomalla G, Fiehler J, Kohrmann M, Molina CA, Neumann-Haefelin T, Ribo M, Singer OC, Zaro-Weber O, Sobesky J. MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows: an analysis of 1210 patients. Stroke. 2007;38:2640-2645.