메뉴 건너뛰기




Volumn 1, Issue 2, 2008, Pages 57-64

CHFR: A novel mitotic checkpoint protein and regulator of tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords


EID: 58149329306     PISSN: None     EISSN: 19365233     Source Type: Journal    
DOI: 10.1593/tlo.08109     Document Type: Article
Times cited : (33)

References (64)
  • 1
    • 0034721154 scopus 로고    scopus 로고
    • Chfr defines a mitotic stress checkpoint that delays entry into metaphase
    • Scolnick DM and Halazonetis TD (2000). Chfr defines a mitotic stress checkpoint that delays entry into metaphase. Nature 406, 430-435.
    • (2000) Nature , vol.406 , pp. 430-435
    • Scolnick, D.M.1    Halazonetis, T.D.2
  • 2
    • 7544227866 scopus 로고    scopus 로고
    • PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein
    • Daniels MJ, Marson A, and Venkitaraman AR (2004). PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein. Nat Struct Mol Biol 11, 1114-1121.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1114-1121
    • Daniels, M.J.1    Marson, A.2    Venkitaraman, A.R.3
  • 3
    • 45849146665 scopus 로고    scopus 로고
    • The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by RING finger domain
    • Fukuda T, Kondo Y, and Nakagama H (2008). The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by RING finger domain. PLoS ONE 3, e1776.
    • (2008) PLoS ONE , vol.3
    • Fukuda, T.1    Kondo, Y.2    Nakagama, H.3
  • 4
    • 0242551691 scopus 로고    scopus 로고
    • The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains
    • Bothos J, Summers MK, Venere M, Scolnick DM, and Halazonetis TD (2003). The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains. Oncogene 22, 7101-7107.
    • (2003) Oncogene , vol.22 , pp. 7101-7107
    • Bothos, J.1    Summers, M.K.2    Venere, M.3    Scolnick, D.M.4    Halazonetis, T.D.5
  • 9
    • 3343006384 scopus 로고    scopus 로고
    • Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr
    • Fraschini R, Bilotta D, Lucchini G, and Piatti S (2004). Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell 15, 3796-3810.
    • (2004) Mol Biol Cell , vol.15 , pp. 3796-3810
    • Fraschini, R.1    Bilotta, D.2    Lucchini, G.3    Piatti, S.4
  • 10
    • 18744398396 scopus 로고    scopus 로고
    • Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN)
    • Guertin DA, Venkatram S, Gould KL, and McCollum D (2002). Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN). Dev Cell 3, 779-790.
    • (2002) Dev Cell , vol.3 , pp. 779-790
    • Guertin, D.A.1    Venkatram, S.2    Gould, K.L.3    McCollum, D.4
  • 11
    • 0029844745 scopus 로고    scopus 로고
    • The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised
    • Murone M and Simanis V (1996). The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised. EMBO J 15, 6605-6616.
    • (1996) EMBO J , vol.15 , pp. 6605-6616
    • Murone, M.1    Simanis, V.2
  • 12
    • 39849092543 scopus 로고    scopus 로고
    • Regulation of mitotic exit by the RNF8 ubiquitin ligase
    • Plans V, Guerra-Rebollo M, and Thomson TM (2008). Regulation of mitotic exit by the RNF8 ubiquitin ligase. Oncogene 27, 1355-1365.
    • (2008) Oncogene , vol.27 , pp. 1355-1365
    • Plans, V.1    Guerra-Rebollo, M.2    Thomson, T.M.3
  • 13
    • 36249031962 scopus 로고    scopus 로고
    • RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
    • Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB, and Chen J (2007). RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 131, 901-914.
    • (2007) Cell , vol.131 , pp. 901-914
    • Huen, M.S.1    Grant, R.2    Manke, I.3    Minn, K.4    Yu, X.5    Yaffe, M.B.6    Chen, J.7
  • 14
    • 36248966246 scopus 로고    scopus 로고
    • RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
    • Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, and Lukas J (2007). RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131, 887-900.
    • (2007) Cell , vol.131 , pp. 887-900
    • Mailand, N.1    Bekker-Jensen, S.2    Faustrup, H.3    Melander, F.4    Bartek, J.5    Lukas, C.6    Lukas, J.7
  • 15
    • 0345305711 scopus 로고    scopus 로고
    • Promotion of mitosis by activated protein kinase B after DNA damage involves polo-like kinase 1 and checkpoint protein CHFR
    • Shtivelman E (2003). Promotion of mitosis by activated protein kinase B after DNA damage involves polo-like kinase 1 and checkpoint protein CHFR. Mol Cancer Res 1, 959-969.
    • (2003) Mol Cancer Res , vol.1 , pp. 959-969
    • Shtivelman, E.1
  • 16
    • 17844387881 scopus 로고    scopus 로고
    • The CHFR mitotic checkpoint protein delays cell cycle progression by excluding cyclin B1 from the nucleus
    • Summers MK, Bothos J, and Halazonetis TD (2005). The CHFR mitotic checkpoint protein delays cell cycle progression by excluding cyclin B1 from the nucleus. Oncogene 24, 2589-2598.
    • (2005) Oncogene , vol.24 , pp. 2589-2598
    • Summers, M.K.1    Bothos, J.2    Halazonetis, T.D.3
  • 19
    • 34447130265 scopus 로고    scopus 로고
    • Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: Implications for tumor suppression
    • Privette LM, Gonzalez ME, Ding L, Kleer CG, and Petty EM (2007). Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression. Cancer Res 67, 6064-6074.
    • (2007) Cancer Res , vol.67 , pp. 6064-6074
    • Privette, L.M.1    Gonzalez, M.E.2    Ding, L.3    Kleer, C.G.4    Petty, E.M.5
  • 20
    • 0347988069 scopus 로고    scopus 로고
    • 2/M checkpoint defects in breast cancer cells
    • 2/M checkpoint defects in breast cancer cells. Mol Carcinog 39, 26-33.
    • (2004) Mol Carcinog , vol.39 , pp. 26-33
    • Erson, A.E.1    Petty, E.M.2
  • 21
    • 4143140977 scopus 로고    scopus 로고
    • Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells
    • Matsusaka T and Pines J (2004). Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells. J Cell Biol 166, 507-516.
    • (2004) J Cell Biol , vol.166 , pp. 507-516
    • Matsusaka, T.1    Pines, J.2
  • 24
    • 45849111392 scopus 로고    scopus 로고
    • Loss of CHFR expression in mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint
    • Privette LM, Weier JF, Nguyen HN, Yu X, and Petty EM (2008). Loss of CHFR expression in mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint. Neoplasia 10, 643-652.
    • (2008) Neoplasia , vol.10 , pp. 643-652
    • Privette, L.M.1    Weier, J.F.2    Nguyen, H.N.3    Yu, X.4    Petty, E.M.5
  • 25
    • 39349090679 scopus 로고    scopus 로고
    • Discovery of candidate KEN box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation
    • Michael S, Trave G, Ramu C, Chica C, and Gibson TJ (2008). Discovery of candidate KEN box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation. Bioinformatics 24, 453-457.
    • (2008) Bioinformatics , vol.24 , pp. 453-457
    • Michael, S.1    Trave, G.2    Ramu, C.3    Chica, C.4    Gibson, T.J.5
  • 26
    • 0141429171 scopus 로고    scopus 로고
    • Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
    • Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M, Hatakeyama K, and Saya H (2003). Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 114, 585-598.
    • (2003) Cell , vol.114 , pp. 585-598
    • Hirota, T.1    Kunitoku, N.2    Sasayama, T.3    Marumoto, T.4    Zhang, D.5    Nitta, M.6    Hatakeyama, K.7    Saya, H.8
  • 27
    • 34247515916 scopus 로고    scopus 로고
    • Deubiquitination of Chfr, a checkpoint protein, by USP7/HAUSP regulates its stability and activity
    • Oh YM, Yoo SJ, and Seol JH (2007). Deubiquitination of Chfr, a checkpoint protein, by USP7/HAUSP regulates its stability and activity. Biochem Biophys Res Commun 357, 615-619.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 615-619
    • Oh, Y.M.1    Yoo, S.J.2    Seol, J.H.3
  • 30
    • 38349057540 scopus 로고    scopus 로고
    • Coding region polymorphisms in the CHFR mitotic stress checkpoint gene are associated with colorectal cancer risk
    • Kang HC, Kim IJ, Jang SG, Hong SH, Hwang JA, Shin HR, and Park JG (2008). Coding region polymorphisms in the CHFR mitotic stress checkpoint gene are associated with colorectal cancer risk. Cancer Lett 260, 170-179.
    • (2008) Cancer Lett , vol.260 , pp. 170-179
    • Kang, H.C.1    Kim, I.J.2    Jang, S.G.3    Hong, S.H.4    Hwang, J.A.5    Shin, H.R.6    Park, J.G.7
  • 34
    • 27744499967 scopus 로고    scopus 로고
    • Mapping of candidate tumor suppressor genes on chromosome 12 in adenoid cystic carcinoma
    • Rutherford S, Hampton GM, Frierson HF, and Moskaluk CA (2005). Mapping of candidate tumor suppressor genes on chromosome 12 in adenoid cystic carcinoma. Lab Invest 85, 1076-1085.
    • (2005) Lab Invest , vol.85 , pp. 1076-1085
    • Rutherford, S.1    Hampton, G.M.2    Frierson, H.F.3    Moskaluk, C.A.4
  • 39
    • 22344454699 scopus 로고    scopus 로고
    • CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype
    • Brandes JC, van Engeland M, Wouters KA, Weijenberg MP, and Herman JG (2005). CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype. Carcinogenesis 26, 1152-1156.
    • (2005) Carcinogenesis , vol.26 , pp. 1152-1156
    • Brandes, J.C.1    van Engeland, M.2    Wouters, K.A.3    Weijenberg, M.P.4    Herman, J.G.5
  • 42
    • 0037275750 scopus 로고    scopus 로고
    • Frequent hypermethylation of the 5′ CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer
    • Corn PG, Summers MK, Fogt F, Virmani AK, Gazdar AF, Halazonetis TD, and El-Deiry WS (2003). Frequent hypermethylation of the 5′ CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer. Carcinogenesis 24, 47-51.
    • (2003) Carcinogenesis , vol.24 , pp. 47-51
    • Corn, P.G.1    Summers, M.K.2    Fogt, F.3    Virmani, A.K.4    Gazdar, A.F.5    Halazonetis, T.D.6    El-Deiry, W.S.7
  • 43
    • 40549090918 scopus 로고    scopus 로고
    • Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations
    • Derks S, Postma C, Carvalho B, van den Bosch SM, Moerkerk PT, Herman JG, Weijenberg MP, de Bruine AP, Meijer GA, and van Engeland M (2008). Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations. Carcinogenesis 29, 434-439.
    • (2008) Carcinogenesis , vol.29 , pp. 434-439
    • Derks, S.1    Postma, C.2    Carvalho, B.3    van den Bosch, S.M.4    Moerkerk, P.T.5    Herman, J.G.6    Weijenberg, M.P.7    de Bruine, A.P.8    Meijer, G.A.9    van Engeland, M.10
  • 46
    • 15244340291 scopus 로고    scopus 로고
    • Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias
    • Homma N, Tamura G, Honda T, Jin Z, Ohmura K, Kawata S, and Motoyama T (2005). Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias. Virchows Arch 446, 120-126.
    • (2005) Virchows Arch , vol.446 , pp. 120-126
    • Homma, N.1    Tamura, G.2    Honda, T.3    Jin, Z.4    Ohmura, K.5    Kawata, S.6    Motoyama, T.7
  • 47
    • 2942580970 scopus 로고    scopus 로고
    • Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia
    • Honda T, Tamura G, Waki T, Kawata S, Nishizuka S, and Motoyama T (2004). Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia. Br J Cancer 90, 2013-2016.
    • (2004) Br J Cancer , vol.90 , pp. 2013-2016
    • Honda, T.1    Tamura, G.2    Waki, T.3    Kawata, S.4    Nishizuka, S.5    Motoyama, T.6
  • 50
    • 38749150922 scopus 로고    scopus 로고
    • CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci
    • Kawasaki T, Ohnishi M, Nosho K, Suemoto Y, Kirkner GJ, Meyerhardt JA, Fuchs CS, and Ogino S (2008). CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci. Mod Pathol 21, 245-255.
    • (2008) Mod Pathol , vol.21 , pp. 245-255
    • Kawasaki, T.1    Ohnishi, M.2    Nosho, K.3    Suemoto, Y.4    Kirkner, G.J.5    Meyerhardt, J.A.6    Fuchs, C.S.7    Ogino, S.8
  • 51
    • 33645287282 scopus 로고    scopus 로고
    • The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer
    • Koga Y, Kitajima Y, Miyoshi A, Sato K, Sato S, and Miyazaki K (2006). The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer. J Gastroenterol 41, 133-139.
    • (2006) J Gastroenterol , vol.41 , pp. 133-139
    • Koga, Y.1    Kitajima, Y.2    Miyoshi, A.3    Sato, K.4    Sato, S.5    Miyazaki, K.6
  • 52
  • 54
    • 33845921773 scopus 로고    scopus 로고
    • Aberrant methylation of the CHFR gene is frequently detected in noninvasive colorectal cancer
    • Morioka Y, Hibi K, Sakai M, Koike M, Fujiwara M, Kodera Y, Ito K, and Nakao A (2006). Aberrant methylation of the CHFR gene is frequently detected in noninvasive colorectal cancer. Anticancer Res 26, 4267-4270.
    • (2006) Anticancer Res , vol.26 , pp. 4267-4270
    • Morioka, Y.1    Hibi, K.2    Sakai, M.3    Koike, M.4    Fujiwara, M.5    Kodera, Y.6    Ito, K.7    Nakao, A.8
  • 62
    • 32144440317 scopus 로고    scopus 로고
    • DNA methylation of CHFR is not a predictor of the response to docetaxel and paclitaxel in advanced and recurrent gastric cancer
    • Yoshida K, Hamai Y, Suzuki T, Sanada Y, Oue N, and Yasui W (2006). DNA methylation of CHFR is not a predictor of the response to docetaxel and paclitaxel in advanced and recurrent gastric cancer. Anticancer Res 26, 49-54.
    • (2006) Anticancer Res , vol.26 , pp. 49-54
    • Yoshida, K.1    Hamai, Y.2    Suzuki, T.3    Sanada, Y.4    Oue, N.5    Yasui, W.6
  • 63
    • 34248138871 scopus 로고    scopus 로고
    • Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis
    • Milne AN, Sitarz R, Carvalho R, Polak MM, Ligtenberg M, Pauwels P, Offerhaus GJ, and Weterman MA (2007). Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis. Hum Pathol 38, 903-913.
    • (2007) Hum Pathol , vol.38 , pp. 903-913
    • Milne, A.N.1    Sitarz, R.2    Carvalho, R.3    Polak, M.M.4    Ligtenberg, M.5    Pauwels, P.6    Offerhaus, G.J.7    Weterman, M.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.