A novel method to incorporate bioactive cytokines as adjuvants on the surface of virus particles

Journal of Interferon and Cytokine Research

Volumn 29, Issue 1, 2009, Pages 9-22

  Yang, Yufang ^a   Leggat, David ^a   Herbert, Andrew ^a,b   Roberts, Paul C ^a,b,c   Sundick, Roys S ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

^c VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; AVIAN INFLUENZA VACCINE; CONCANAVALIN A; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; INACTIVATED VACCINE; INFLUENZA VACCINE; INTERLEUKIN 2; VIRUS ANTIBODY;

ANIMAL CELL; ARTICLE; BIOASSAY; BONE MARROW CELL; CELL STRAIN COS7; CHICKEN; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; IMMUNOGENICITY; IMMUNOSTIMULATION; INFLUENZA VIRUS; NONHUMAN; PRIORITY JOURNAL; VACCINATION; VIRUS ENVELOPE; VIRUS INACTIVATION; VIRUS INFECTION; VIRUS PARTICLE; VIRUS PURIFICATION; WESTERN BLOTTING;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; CELL LINE; CHICKENS; DOGS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INFLUENZA A VIRUS; INFLUENZA VACCINES; INTERLEUKIN-2; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; VACCINES, SYNTHETIC; VIRION;

GALLUS GALLUS; ORTHOMYXOVIRIDAE;

EID: 58149328743     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.2008.0017     Document Type: Article

References (43)

1. Avery S, Rothwell L, Degen WD, Schijns VE, Young J, Kaufman J, Kaiser P. 2004. Characterization of the first nonmammalian T2 cytokine gene cluster: the cluster contains functional single-copy genes for IL-3, IL-4, IL-13, and GM-CSF, a gene for IL-5 that appears to be a pseudogene, and a gene encoding another cytokinelike transcript, KK34. J Interferon Cytokine Res 24(10):600-610.
2. Ben-Yehuda A, Joseph A, Barenholz Y, Zeira E, Even-Chen S, Louria-Hayon I, Babai I, Zakay-Rones Z, Greenbaum E, Galprin I and others. 2003a. Immunogenicity and safety of a novel IL-2-supplemented liposomal influenza vaccine (INFLUSOME-VAC) in nursing-home residents. Vaccine 21(23):3169-3178.
3. Ben-Yehuda A, Joseph A, Zeira E, Even-Chen S, Louria-Hayon I, Babai I, Zakay-Rones Z, Greenbaum E, Barenholz Y, Kedar E. 2003b. Immunogenicity and safety of a novel liposomal influenza subunit vaccine (INFLUSOME-VAC) in young adults. J Med Virol 69(4):560-567.
4. Bukreyev A, Belyakov IM. 2002. Expression of immunomodulating molecules by recombinant viruses: can the immunogenicity of live virus vaccines be improved? Expert Rev Vaccines 1(2):233-245.
5. Bukreyev A, Skiadopoulos MH, McAuliffe J, Murphy BR, Collins PL, Schmidt AC. 2002. More antibody with less antigen: can immunogenicity of attenuated live virus vaccines be improved? Proc Natl Acad Sci USA 99(26):16987-16991.
6. Chakrabarti R, Chang Y, Song K, Prud'homme GJ. 2004. Plasmids encoding membrane-bound IL-4 or IL-12 strongly costimulate DNA vaccination against carcinoembryonic antigen (CEA). Vaccine 22(9-10):1199-1205.
7. Chang DZ, Lomazow W, Joy Somberg C, Stan R, Perales MA. 2004. Granulocyte-macrophage colony stimulating factor: an adjuvant for cancer vaccines. Hematology 9(3):207-215.
8. Dillon PJ, Rosen CA. 1990. A rapid method for the construction of synthetic genes using the polymerase chain reaction. Biotechniques 9(3):298-300.
9. Djeraba A, Musset E, Lowenthal JW, Boyle DB, Chausse AM, Peloille M, Quere P. 2002. Protective effect of avian myelomonocytic growth factor in infection with Marek's disease virus. J Virol 76(3):1062-1070.
10. Faulkner L, Buchan G, Lockhart E, Slobbe L, Wilson M, Baird M. 2001. IL-2 linked to a peptide from influenza hemagglutinin enhances T cell activation by affecting the antigen-presentation function of bone marrow-derived dendritic cells. Int Immunol 13(6):713-721.
11. Giansanti F, Giardi MF, Botti D. 2006. Avian cytokines - an overview. Curr Pharm Des 12(24):3083-3099.
12. Hu W, Kolodsick JE, Stepaniak JA, Sundick RS, eds. 2001. Enhanced immune reponses to Marek's disease virus glycoprotein B by co-injection with recombinant chicken IL-2. Kennett Square: American Association Avian Pathologists. pp. 269-274.
13. Hulse DJ, Romero CH. 2004. Partial protection against infectious bursal disease virus through DNA-mediated vaccination with the VP2 capsid protein and chicken IL-2 genes. Vaccine 22(9-10):1249-1259.
14. Kaiser P, Poh TY, Rothwell L, Avery S, Balu S, Pathania US, Hughes S, Goodchild M, Morrell S, Watson M and others. 2005. A genomic analysis of chicken cytokines and chemokines. J Interferon Cytokine Res 25(8):467-484.
15. Kim YS, Sonn CH, Paik SG, Bothwell AL. 2000. Tumor cells expressing membrane-bound form of IL-4 induce antitumor immunity. Gene Ther 7(10):837-843.
16. Kittel C, Ferko B, Kurz M, Voglauer R, Sereinig S, Romanova J, Stiegler G, Katinger H, Egorov A. 2005. Generation of an influenza A virus vector expressing biologically active human interleukin-2 from the NS gene segment. J Virol 79(16):10672-10677.
17. Kolodsick JE, Stepaniak JA, Hu W, Sundick RS. 2001. Mutational analysis of chicken interleukin 2. Cytokine 13(6):317-324.
18. Kueng HJ, Leb VM, Haiderer D, Raposo G, Thery C, Derdak SV, Schmetterer KG, Neunkirchner A, Sillaber C, Seed B and others. 2007. General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol 81(16):8666-8676.
19. Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y and others. 2005. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. J Immunol 175(1):112-123.
20. Lasek W, Basak G, Switaj T, Jakubowska AB, Wysocki PJ, Mackiewicz A, Drela N, Jalili A, Kaminski R, Kozar K and others. 2004. Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice. Cancer Immunol Immunother 53(4):363-372.
21. Li J, Liang X, Huang Y, Meng S, Xie R, Deng R, Yu L. 2004. Enhancement of the immunogenicity of DNA vaccine against infectious bursal disease virus by co-delivery with plasmid encoding chicken interleukin 2. Virology 329(1):89-100.
22. Lowenthal JW, York JJ, O'Neil TE, Steven RA, Strom DG, Digby MR. 1998. Potential use of cytokine therapy in poultry. Vet Immunol Immunopathol 63(1-2):191-198.
23. Luke CJ, Subbarao K. 2006. Vaccines for pandemic influenza. Emerg Infect Dis 12(1):66-72.
24. Nagarajan S, Selvaraj P. 2002. Glycolipid-anchored IL-12 expressed on tumor cell surface induces antitumor immune response. Cancer Res 62(10):2869-2874.
25. Nizard P, Gross DA, Babon A, Chenal A, Beaumelle B, Kosmatopoulos K, Gillet D. 2003. Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice. J Immunother 26(1):63-71.
26. Okada H, Villa L, Attanucci J, Erff M, Fellows WK, Lotze MT, Pollack IF, Chambers WH. 2001. Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells. Gene Ther 8(15):1157-1166.
27. Orson FM, Kinsey BM, Densmore CL, Nguyen T, Wu Y, Mbawuike IN, Wyde PR. 2006. Protection against influenza infection by cytokine-enhanced aerosol genetic immunization. J Gene Med 8(4):488-497.
28. Poloso NJ, Nagarajan S, Mejia-Oneta JM, Selvaraj P. 2002. GPIanchoring of GM-CSF results in active membrane-bound and partially shed cytokine. Mol Immunol 38(11):803-816.
29. Roberts PC, Robert A. Lamb, Richard W. Compans. 1998. The M1 and M2 proteins of influenza a virus are important determinants in filamentous particle formation. Virology 240:127-137.
30. Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE, Cole DJ. 2002. Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination with peptide-pulsed dendritic cells. J Immunol 169(9):4928-4935.
31. Schijns VE, Weining KC, Nuijten P, Rijke EO, Staeheli P. 2000. Immunoadjuvant activities of E. coli- and plasmid-expressed recombinant chicken IFN-alpha/beta, IFN-gamma and IL-1beta in 1-day- and 3-week-old chickens. Vaccine 18(20):2147-2154.
32. Smith NM, Bresee JS, Shay DK, Uyeki TM, Cox NJ, Strikas RA. 2006. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 55(RR-10):1-42.
33. Soo Hoo W, Lundeen KA, Kohrumel JR, Pham NL, Brostoff SW, Bartholomew RM, Carlo DJ. 1999. Tumor cell surface expression of granulocyte-macrophage colony-stimulating factor elicits antitumor immunity and protects from tumor challenge in the P815 mouse mastocytoma tumor model. J Immunol 162(12):7343-7349.
34. Stepaniak JA, Shuster JE, Hu W, Sundick RS. 1999. Production and in vitro characterization of recombinant chicken interleukin-2. J Interferon Cytokine Res 19(5):515-526.
35. Takehara K, Kobayashi K, Ruttanapumma R, Kamikawa M, Nagata T, Yokomizo Y, Nakamura M. 2003. Adjuvant effect of chicken interferon-gamma for inactivated Salmonella Enteritidis antigen. J Vet Med Sci 65(12):1337-1341.
36. Tarpey I, Davis PJ, Sondermeijer P, van Geffen C, Verstegen I, Schijns VE, Kolodsick J, Sundick R. 2007a. Expression of chicken interleukin-2 by turkey herpesvirus increases the immune reponse against Marek's disease virus but fails to increase protection against virulent challenge. Avian Pathol 36(1):69-74.
37. Tarpey I, van Loon AA, de Haas N, Davis PJ, Orbell S, Cavanagh D, Britton P, Casais R, Sondermeijer P, Sundick R. 2007b. A recombinant turkey herpesvirus expressing chicken interleukin-2 increases the protection provided by in-ovo vaccination with infectious bursal disease and infectious bronchitis virus. Vaccine, 25: 8529-8535.
38. Villinger F, Miller R, Mori K, Mayne AE, Bostik P, Sundstrom JB, Sugimoto C, Ansari AA. 2004. IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques. Vaccine 22(25-26):3510-3521.
39. Wang J, Mauser A, Chao SF, Remington K, Treckmann R, Kaiser K, Pifat D, Hotta J. 2004. Virus inactivation and protein recovery in a novel ultraviolet-C reactor. Vox Sang 86(4):230-238.
40. Webster RG, Cox N, Stohr K. 2002a. WHO Manual on animal influenza diagnosis and surveillance.
41. Yei S, Bartholomew RM, Pezzoli P, Gutierrez A, Gouveia E, Bassett D, Soo Hoo W, Carlo DJ. 2002. Novel membrane-bound GM-CSF vaccines for the treatment of cancer: generation and evaluation of mbGM-CSF mouse B16F10 melanoma cell vaccine. Gene Ther 9(19):1302-1311.
42. Zhang J, Pekosz A, Lamb RA. 2000. Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins. J Virol 74(10):4634-4644.
43. Zhou JY, Chen JG, Wang JY, Wu JX, Gong H. 2005. cDNA cloning and functional analysis of goose interleukin-2. Cytokine 30(6):328-338.