A prostate cancer vaccine comprising whole cells secreting IL-7, effective against subcutaneous challenge, requires local GM-CSF for intra-prostatic efficacy

Cancer Immunology, Immunotherapy

Volumn 58, Issue 3, 2009, Pages 373-381

  Schroten Loef, Caroline ^a   De Ridder, Corrina M A ^a   Reneman, Suzanne ^a   Crezee, Marije ^a   Dalgleish, Angus ^b   Todryk, Stephen M ^c   Bangma, Chris H ^a   Kraaij, Robert ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NORTHUMBRIA UNIVERSITY   (United Kingdom)

Author keywords

Cytokines; Immunotherapy; MPR model; Prostate cancer; Whole cell vaccine

Indexed keywords

CANCER VACCINE; CD40 LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 7;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; C57BL 6 MOUSE; CANCER CELL; CANCER CELL CULTURE; CANCER IMMUNIZATION; CANCER SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE FREE SURVIVAL; DRUG EFFICACY; IMMUNE RESPONSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROVOCATION TEST; T LYMPHOCYTE; WHOLE CELL;

ANIMALS; CANCER VACCINES; CELL LINE, TUMOR; CYTOKINES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-7; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROSTATIC NEOPLASMS; T-LYMPHOCYTES; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 58149313844     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-008-0560-z     Document Type: Article

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