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Volumn 155, Issue 2, 2009, Pages 249-256

CD40-activated B cells can be generated in high number and purity in cancer patients: Analysis of immunogenicity and homing potential

Author keywords

Antigen presenting cells; CD40 activated B cells; Tumour immunothrapy

Indexed keywords

CD40 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR7; DENDRITIC CELL VACCINE; L SELECTIN; RITUXIMAB;

EID: 58149312923     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03820.x     Document Type: Article
Times cited : (42)

References (56)
  • 1
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med 2004 10 : 909 15.
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 2
    • 0037103261 scopus 로고    scopus 로고
    • Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: Prostaglandin E2 regulates the migratory capacity of specific DC subsets
    • Luft T, Jefford M, Luetjens P et al. Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E2 regulates the migratory capacity of specific DC subsets. Blood 2002 100 : 1362 72.
    • (2002) Blood , vol.100 , pp. 1362-1372
    • Luft, T.1    Jefford, M.2    Luetjens, P.3
  • 3
    • 0035242024 scopus 로고    scopus 로고
    • Prostaglandin E2 up-regulates macrophage-derived chemokine production but suppresses IFN-inducible protein-10 production by APC
    • Kuroda E, Sugiura T, Okada K, Zeki K, Yamashita U. Prostaglandin E2 up-regulates macrophage-derived chemokine production but suppresses IFN-inducible protein-10 production by APC. J Immunol 2001 166 : 1650 8.
    • (2001) J Immunol , vol.166 , pp. 1650-1658
    • Kuroda, E.1    Sugiura, T.2    Okada, K.3    Zeki, K.4    Yamashita, U.5
  • 4
    • 33745622659 scopus 로고    scopus 로고
    • CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: Additional mechanisms of T-cell inhibition
    • von Bergwelt-Baildon M, Popov A, Saric T et al. CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. Blood 2006 108 : 228 37.
    • (2006) Blood , vol.108 , pp. 228-237
    • Von Bergwelt-Baildon, M.1    Popov, A.2    Saric, T.3
  • 5
    • 0031179646 scopus 로고    scopus 로고
    • IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
    • Kalinski P, Hilkens CM, Snijders A, Snijdewint FG, Kapsenberg ML. IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J Immunol 1997 159 : 28 35.
    • (1997) J Immunol , vol.159 , pp. 28-35
    • Kalinski, P.1    Hilkens, C.M.2    Snijders, A.3    Snijdewint, F.G.4    Kapsenberg, M.L.5
  • 6
    • 0032709778 scopus 로고    scopus 로고
    • IL-10 promotes lung cancer growth by suppressing both T cell and APC function
    • Sharma S, Stolina M, Lin Y et al. IL-10 promotes lung cancer growth by suppressing both T cell and APC function. J Immunol 1999 163 : 5020 8.
    • (1999) J Immunol , vol.163 , pp. 5020-5028
    • Sharma, S.1    Stolina, M.2    Lin, Y.3
  • 7
    • 0036530016 scopus 로고    scopus 로고
    • CD4+ and CD8+ anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity
    • Steinbrink K, Graulich E, Kubsch S, Knop J, Enk A. CD4+ and CD8+ anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 2002 99 : 2468 76.
    • (2002) Blood , vol.99 , pp. 2468-2476
    • Steinbrink, K.1    Graulich, E.2    Kubsch, S.3    Knop, J.4    Enk, A.5
  • 8
    • 0034161681 scopus 로고    scopus 로고
    • TGF-{beta}1 reciprocally controls chemotaxis of human peripheral blood monocyte-derived dendritic cells via chemokine receptors
    • Sato K, Kawasaki H, Nagayama H et al. TGF-{beta}1 reciprocally controls chemotaxis of human peripheral blood monocyte-derived dendritic cells via chemokine receptors. J Immunol 2000 164 : 2285 95.
    • (2000) J Immunol , vol.164 , pp. 2285-2295
    • Sato, K.1    Kawasaki, H.2    Nagayama, H.3
  • 9
    • 0037446966 scopus 로고    scopus 로고
    • Transforming growth factor {beta} inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines
    • Kobie J, Wu R, Kurt R et al. Transforming growth factor {beta} inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines. Cancer Res 2003 63 : 1860 4.
    • (2003) Cancer Res , vol.63 , pp. 1860-1864
    • Kobie, J.1    Wu, R.2    Kurt, R.3
  • 10
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich DI, Chen HL, Girgis KR et al. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 1996 2 : 1096 103.
    • (1996) Nat Med , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3
  • 11
    • 38649110793 scopus 로고    scopus 로고
    • Introduction of functional chimeric E/L-selectin by RNA electroporation to target dendritic cells from blood to lymph nodes
    • Dorrie J, Schaft N, Muller I et al. Introduction of functional chimeric E/L-selectin by RNA electroporation to target dendritic cells from blood to lymph nodes. Cancer Immunol Immunother 2008 57 : 467 77.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 467-477
    • Dorrie, J.1    Schaft, N.2    Muller, I.3
  • 12
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice
    • Serreze DV, Fleming SA, Chapman HD, Richard SD, Leiter EH, Tisch RM. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Immunol 1998 161 : 3912 18.
    • (1998) J Immunol , vol.161 , pp. 3912-3918
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, H.D.3    Richard, S.D.4    Leiter, E.H.5    Tisch, R.M.6
  • 13
    • 22744433513 scopus 로고    scopus 로고
    • Concerted antigen presentation by dendritic cells and B cells is necessary for optimal CD4 T-cell immunity in vivo
    • Kleindienst P, Brocker T. Concerted antigen presentation by dendritic cells and B cells is necessary for optimal CD4 T-cell immunity in vivo. Immunology 2005 115 : 556 64.
    • (2005) Immunology , vol.115 , pp. 556-564
    • Kleindienst, P.1    Brocker, T.2
  • 14
    • 33749155438 scopus 로고    scopus 로고
    • B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation
    • Yan J, Harvey BP, Gee RJ, Shlomchik MJ, Mamula MJ. B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation. J Immunol 2006 177 : 4481 7.
    • (2006) J Immunol , vol.177 , pp. 4481-4487
    • Yan, J.1    Harvey, B.P.2    Gee, R.J.3    Shlomchik, M.J.4    Mamula, M.J.5
  • 15
    • 0026451165 scopus 로고
    • B cells turn off virgin but not memory T cells
    • Fuchs EJ, Matzinger P. B cells turn off virgin but not memory T cells. Science 1992 258 : 1156 9.
    • (1992) Science , vol.258 , pp. 1156-1159
    • Fuchs, E.J.1    Matzinger, P.2
  • 16
    • 0028009223 scopus 로고
    • Tolerogenicity of resting and activated B cells
    • Gilbert KM, Weigle WO. Tolerogenicity of resting and activated B cells. J Exp Med 1994 179 : 249 58.
    • (1994) J Exp Med , vol.179 , pp. 249-258
    • Gilbert, K.M.1    Weigle, W.O.2
  • 17
    • 0037606009 scopus 로고    scopus 로고
    • B cells activated by lipopolysaccharide, but not by anti-Ig and anti-CD40 antibody, induce anergy in CD8+ T cells: Role of TGF-beta 1
    • Parekh VV, Prasad DV, Banerjee PP, Joshi BN, Kumar A, Mishra GC. B cells activated by lipopolysaccharide, but not by anti-Ig and anti-CD40 antibody, induce anergy in CD8+ T cells: role of TGF-beta 1. J Immunol 2003 170 : 5897 911.
    • (2003) J Immunol , vol.170 , pp. 5897-5911
    • Parekh, V.V.1    Prasad, D.V.2    Banerjee, P.P.3    Joshi, B.N.4    Kumar, A.5    Mishra, G.C.6
  • 18
    • 10844251061 scopus 로고    scopus 로고
    • B-Lymphocytes activated by CD40 ligand induce an antigen-specific anti-tumour immune response by direct and indirect activation of CD8(+) T-cells
    • Ritchie DS, Yang J, Hermans IF, Ronchese F. B-Lymphocytes activated by CD40 ligand induce an antigen-specific anti-tumour immune response by direct and indirect activation of CD8(+) T-cells. Scand J Immunol 2004 60 : 543 51.
    • (2004) Scand J Immunol , vol.60 , pp. 543-551
    • Ritchie, D.S.1    Yang, J.2    Hermans, I.F.3    Ronchese, F.4
  • 19
    • 1542343957 scopus 로고    scopus 로고
    • RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: Implications for pediatric immunotherapy
    • Coughlin CM, Vance BA, Grupp SA, Vonderheide RH. RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy. Blood 2004 103 : 2046 54.
    • (2004) Blood , vol.103 , pp. 2046-2054
    • Coughlin, C.M.1    Vance, B.A.2    Grupp, S.A.3    Vonderheide, R.H.4
  • 20
    • 20444471109 scopus 로고    scopus 로고
    • In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins
    • Fujiwara H, Melenhorst JJ, El Ouriaghli F et al. In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins. Clin Cancer Res 2005 11 : 4495 503.
    • (2005) Clin Cancer Res , vol.11 , pp. 4495-4503
    • Fujiwara, H.1    Melenhorst, J.J.2    El Ouriaghli, F.3
  • 21
    • 0037601712 scopus 로고    scopus 로고
    • CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells
    • Lapointe R, Bellemare-Pelletier A, Housseau F, Thibodeau J, Hwu P. CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003 63 : 2836 43.
    • (2003) Cancer Res , vol.63 , pp. 2836-2843
    • Lapointe, R.1    Bellemare-Pelletier, A.2    Housseau, F.3    Thibodeau, J.4    Hwu, P.5
  • 22
    • 33645525541 scopus 로고    scopus 로고
    • CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: Potential as cellular adjuvants
    • von Bergwelt-Baildon M, Shimabukuro-Vornhagen A, Popov A et al. CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood 2006 107 : 2786 9.
    • (2006) Blood , vol.107 , pp. 2786-2789
    • Von Bergwelt-Baildon, M.1    Shimabukuro-Vornhagen, A.2    Popov, A.3
  • 23
    • 45749092613 scopus 로고    scopus 로고
    • RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma
    • Mason NJ, Coughlin CM, Overley B et al. RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma. Gene Ther 2008 15 : 955 65.
    • (2008) Gene Ther , vol.15 , pp. 955-965
    • Mason, N.J.1    Coughlin, C.M.2    Overley, B.3
  • 24
    • 0036565877 scopus 로고    scopus 로고
    • Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: Potential for clinical application
    • von Bergwelt-Baildon MS, Vonderheide RH, Maecker B et al. Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood 2002 99 : 3319 25.
    • (2002) Blood , vol.99 , pp. 3319-3325
    • Von Bergwelt-Baildon, M.S.1    Vonderheide, R.H.2    Maecker, B.3
  • 25
    • 2342640119 scopus 로고    scopus 로고
    • Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA
    • Barrou B, Benoit G, Ouldkaci M et al. Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA. Cancer Immunol Immunother 2004 53 : 453 60.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 453-460
    • Barrou, B.1    Benoit, G.2    Ouldkaci, M.3
  • 26
    • 33846021299 scopus 로고    scopus 로고
    • Preliminary analysis of patients with progressive renal cell carcinoma vaccinated with CA9-peptide-pulsed mature dendritic cells
    • Bleumer I, Tiemessen DM, Oosterwijk-Wakka JC et al. Preliminary analysis of patients with progressive renal cell carcinoma vaccinated with CA9-peptide-pulsed mature dendritic cells. J Immunother 2007 30 : 116 22.
    • (2007) J Immunother , vol.30 , pp. 116-122
    • Bleumer, I.1    Tiemessen, D.M.2    Oosterwijk-Wakka, J.C.3
  • 27
    • 0034043167 scopus 로고    scopus 로고
    • Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer
    • Burch PA, Breen JK, Buckner JC et al. Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer. Clin Cancer Res 2000 6 : 2175 82.
    • (2000) Clin Cancer Res , vol.6 , pp. 2175-2182
    • Burch, P.A.1    Breen, J.K.2    Buckner, J.C.3
  • 28
    • 0035892759 scopus 로고    scopus 로고
    • Dendritic cell-based xenoantigen vaccination for prostate cancer immunotherapy
    • Fong L, Brockstedt D, Benike C et al. Dendritic cell-based xenoantigen vaccination for prostate cancer immunotherapy. J Immunol 2001 167 : 7150 6.
    • (2001) J Immunol , vol.167 , pp. 7150-7156
    • Fong, L.1    Brockstedt, D.2    Benike, C.3
  • 29
    • 10744232378 scopus 로고    scopus 로고
    • A pilot trial of tumor lysate-loaded dendritic cells for the treatment of metastatic renal cell carcinoma
    • Gitlitz BJ, Belldegrun AS, Zisman A et al. A pilot trial of tumor lysate-loaded dendritic cells for the treatment of metastatic renal cell carcinoma. J Immunother 2003 26 : 412 19.
    • (2003) J Immunother , vol.26 , pp. 412-419
    • Gitlitz, B.J.1    Belldegrun, A.S.2    Zisman, A.3
  • 30
    • 0036167308 scopus 로고    scopus 로고
    • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
    • Heiser A, Coleman D, Dannull J et al. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 2002 109 : 409 17.
    • (2002) J Clin Invest , vol.109 , pp. 409-417
    • Heiser, A.1    Coleman, D.2    Dannull, J.3
  • 31
    • 0036845714 scopus 로고    scopus 로고
    • Immunotherapy of metastatic renal cell carcinoma with tumor lysate-pulsed autologous dendritic cells
    • Holtl L, Zelle-Rieser C, Gander H et al. Immunotherapy of metastatic renal cell carcinoma with tumor lysate-pulsed autologous dendritic cells. Clin Cancer Res 2002 8 : 3369 76.
    • (2002) Clin Cancer Res , vol.8 , pp. 3369-3376
    • Holtl, L.1    Zelle-Rieser, C.2    Gander, H.3
  • 32
    • 0142021929 scopus 로고    scopus 로고
    • Autologous dendritic cells pulsed with prostatic acid phosphatase (APC8015) for patients with hormone-refractory prostate cancer with a Gleason score < or = 7
    • Lee D. Autologous dendritic cells pulsed with prostatic acid phosphatase (APC8015) for patients with hormone-refractory prostate cancer with a Gleason score < or = 7. Clin Prostate Cancer 2003 2 : 81 3.
    • (2003) Clin Prostate Cancer , vol.2 , pp. 81-83
    • Lee, D.1
  • 33
    • 0034652619 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy of prostate cancer: Immune monitoring of a phase II clinical trial
    • Lodge PA, Jones LA, Bader RA, Murphy GP, Salgaller ML. Dendritic cell-based immunotherapy of prostate cancer: immune monitoring of a phase II clinical trial. Cancer Res 2000 60 : 829 33.
    • (2000) Cancer Res , vol.60 , pp. 829-833
    • Lodge, P.A.1    Jones, L.A.2    Bader, R.A.3    Murphy, G.P.4    Salgaller, M.L.5
  • 34
    • 0036448032 scopus 로고    scopus 로고
    • Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: Preclinical results and outcome of a first clinical phase I/II trial
    • Marten A, Flieger D, Renoth S et al. Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phase I/II trial. Cancer Immunol Immunother 2002 51 : 637 44.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 637-644
    • Marten, A.1    Flieger, D.2    Renoth, S.3
  • 35
    • 27144507469 scopus 로고    scopus 로고
    • Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
    • Mu LJ, Kyte JA, Kvalheim G et al. Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients. Br J Cancer 2005 93 : 749 56.
    • (2005) Br J Cancer , vol.93 , pp. 749-756
    • Mu, L.J.1    Kyte, J.A.2    Kvalheim, G.3
  • 36
    • 0034106147 scopus 로고    scopus 로고
    • Higher-dose and less frequent dendritic cell infusions with PSMA peptides in hormone-refractory metastatic prostate cancer patients
    • Murphy GP, Tjoa BA, Simmons SJ, Rogers MK, Kenny GM, Jarisch J. Higher-dose and less frequent dendritic cell infusions with PSMA peptides in hormone-refractory metastatic prostate cancer patients. Prostate 2000 43 : 59 62.
    • (2000) Prostate , vol.43 , pp. 59-62
    • Murphy, G.P.1    Tjoa, B.A.2    Simmons, S.J.3    Rogers, M.K.4    Kenny, G.M.5    Jarisch, J.6
  • 37
    • 19244365218 scopus 로고    scopus 로고
    • Vaccination of patients with metastatic renal cell carcinoma with autologous dendritic cells pulsed with autologous tumor antigens in combination with interleukin-2: A phase 1 study
    • Oosterwijk-Wakka JC, Tiemessen DM, Bleumer I et al. Vaccination of patients with metastatic renal cell carcinoma with autologous dendritic cells pulsed with autologous tumor antigens in combination with interleukin-2: a phase 1 study. J Immunother 2002 25 : 500 8.
    • (2002) J Immunother , vol.25 , pp. 500-508
    • Oosterwijk-Wakka, J.C.1    Tiemessen, D.M.2    Bleumer, I.3
  • 38
    • 33744483765 scopus 로고    scopus 로고
    • Induction of specific T cell immunity in patients with prostate cancer by vaccination with PSA146-154 peptide
    • Perambakam S, Hallmeyer S, Reddy S et al. Induction of specific T cell immunity in patients with prostate cancer by vaccination with PSA146-154 peptide. Cancer Immunol Immunother 2006 55 : 1033 42.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1033-1042
    • Perambakam, S.1    Hallmeyer, S.2    Reddy, S.3
  • 39
    • 0034554863 scopus 로고    scopus 로고
    • Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
    • Small EJ, Fratesi P, Reese DM et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 2000 18 : 3894 903.
    • (2000) J Clin Oncol , vol.18 , pp. 3894-3903
    • Small, E.J.1    Fratesi, P.2    Reese, D.M.3
  • 40
    • 0038066552 scopus 로고    scopus 로고
    • Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells
    • Su Z, Dannull J, Heiser A et al. Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells. Cancer Res 2003 63 : 2127 33.
    • (2003) Cancer Res , vol.63 , pp. 2127-2133
    • Su, Z.1    Dannull, J.2    Heiser, A.3
  • 41
    • 20144364773 scopus 로고    scopus 로고
    • Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer
    • Su Z, Dannull J, Yang BK et al. Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer. J Immunol 2005 174 : 3798 807.
    • (2005) J Immunol , vol.174 , pp. 3798-3807
    • Su, Z.1    Dannull, J.2    Yang, B.K.3
  • 42
    • 33749606668 scopus 로고    scopus 로고
    • Vaccination of advanced prostate cancer patients with PSCA and PSA peptide-loaded dendritic cells induces DTH responses that correlate with superior overall survival
    • Thomas-Kaskel AK, Zeiser R, Jochim R et al. Vaccination of advanced prostate cancer patients with PSCA and PSA peptide-loaded dendritic cells induces DTH responses that correlate with superior overall survival. Int J Cancer 2006 119 : 2428 34.
    • (2006) Int J Cancer , vol.119 , pp. 2428-2434
    • Thomas-Kaskel, A.K.1    Zeiser, R.2    Jochim, R.3
  • 43
    • 33748302109 scopus 로고    scopus 로고
    • Dendritic cell-based multi-epitope immunotherapy of hormone-refractory prostate carcinoma
    • Waeckerle-Men Y, Uetz-von Allmen E, Fopp M et al. Dendritic cell-based multi-epitope immunotherapy of hormone-refractory prostate carcinoma. Cancer Immunol Immunother 2006 55 : 1524 33.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1524-1533
    • Waeckerle-Men, Y.1    Uetz-Von Allmen, E.2    Fopp, M.3
  • 44
    • 33745247366 scopus 로고    scopus 로고
    • Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients
    • Wierecky J, Muller MR, Wirths S et al. Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients. Cancer Res 2006 66 : 5910 18.
    • (2006) Cancer Res , vol.66 , pp. 5910-5918
    • Wierecky, J.1    Muller, M.R.2    Wirths, S.3
  • 46
    • 43249114364 scopus 로고    scopus 로고
    • Conditional immortalization of human B cells by CD40 ligation
    • Wiesner M, Zentz C, Mayr C et al. Conditional immortalization of human B cells by CD40 ligation. PLoS ONE 2008 3.
    • (2008) PLoS ONE , pp. 3
    • Wiesner, M.1    Zentz, C.2    Mayr, C.3
  • 47
    • 33750033153 scopus 로고    scopus 로고
    • Immortalization of Epstein-Barr virus-negative human B lymphocytes with minimal chromosomal instability
    • Yamashita Y, Tsurumi T, Mori N, Kiyono T. Immortalization of Epstein-Barr virus-negative human B lymphocytes with minimal chromosomal instability. Path Int 2006 56 : 659 67.
    • (2006) Path Int , vol.56 , pp. 659-667
    • Yamashita, Y.1    Tsurumi, T.2    Mori, N.3    Kiyono, T.4
  • 49
    • 33646271857 scopus 로고    scopus 로고
    • Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment
    • Gajewski TF. Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment. Clin Cancer Res 2006 12 : 2326s 30s.
    • (2006) Clin Cancer Res , vol.12
    • Gajewski, T.F.1
  • 50
    • 39649098678 scopus 로고    scopus 로고
    • Tumour immunity: Effector response to tumour and role of the microenvironment
    • Mantovani A, Romero P, Palucka AK, Marincola FM. Tumour immunity: effector response to tumour and role of the microenvironment. Lancet 2008 371 : 771 83.
    • (2008) Lancet , vol.371 , pp. 771-783
    • Mantovani, A.1    Romero, P.2    Palucka, A.K.3    Marincola, F.M.4
  • 51
    • 38649107388 scopus 로고    scopus 로고
    • IDO-expressing regulatory dendritic cells in cancer and chronic infection
    • Popov A, Schultze JL. IDO-expressing regulatory dendritic cells in cancer and chronic infection. J Mol Med 2008 86 : 145 60.
    • (2008) J Mol Med , vol.86 , pp. 145-160
    • Popov, A.1    Schultze, J.L.2
  • 52
    • 33748162638 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells: Cytokine modulation comes of age
    • Rutella S, Danese S, Leone G. Tolerogenic dendritic cells: cytokine modulation comes of age. Blood 2006 108 : 1435 40.
    • (2006) Blood , vol.108 , pp. 1435-1440
    • Rutella, S.1    Danese, S.2    Leone, G.3
  • 53
    • 0037103241 scopus 로고    scopus 로고
    • Efficient generation of antigen-specific cytotoxic T cells using retrovirally transduced CD40-activated B cells
    • Kondo E, Topp MS, Kiem HP et al. Efficient generation of antigen-specific cytotoxic T cells using retrovirally transduced CD40-activated B cells. J Immunol 2002 169 : 2164 71.
    • (2002) J Immunol , vol.169 , pp. 2164-2171
    • Kondo, E.1    Topp, M.S.2    Kiem, H.P.3
  • 54
    • 0031469361 scopus 로고    scopus 로고
    • CD40-activated human B cells: An alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy
    • Schultze JL, Michalak S, Seamon MJ et al. CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J Clin Invest 1997 100 : 2757 65.
    • (1997) J Clin Invest , vol.100 , pp. 2757-2765
    • Schultze, J.L.1    Michalak, S.2    Seamon, M.J.3
  • 56
    • 0345337254 scopus 로고    scopus 로고
    • Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
    • McLaughlin P, Grillo-Lopez AJ, Link BK et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. J Clin Oncol 1998 16 : 2825 33.
    • (1998) J Clin Oncol , vol.16 , pp. 2825-2833
    • McLaughlin, P.1    Grillo-Lopez, A.J.2    Link, B.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.