메뉴 건너뛰기




Volumn 15, Issue 12, 2008, Pages 3521-3531

Phase I/II trial of induction chemotherapy followed by concurrent chemoradiotherapy and surgery for locoregionally Advanced Pancreatic Cancer

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOCETAXEL; DOXIFLURIDINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; MITOMYCIN C; PACLITAXEL; STREPTOZOCIN;

EID: 58149311234     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-008-0152-3     Document Type: Article
Times cited : (39)

References (58)
  • 2
    • 33748445708 scopus 로고    scopus 로고
    • Randomized Phase III trial of gemcitabine pulse cisplatin compared with gemcitabine alone in advanced pancreatic cancer
    • V Heinemann D Quietzsch F Gieseler 2006 Randomized Phase III trial of gemcitabine pulse cisplatin compared with gemcitabine alone in advanced pancreatic cancer J Clin Oncol 24 3946 52
    • (2006) J Clin Oncol , vol.24 , pp. 3946-52
    • Heinemann, V.1    Quietzsch, D.2    Gieseler, F.3
  • 3
    • 0028985078 scopus 로고
    • Treatment and survival in 13,560 patients with pancreatic cancer, and incidence of disease, in the west midlands: An epidemiological study
    • SR Bramhall WH Allum AG Jones 1985 Treatment and survival in 13,560 patients with pancreatic cancer, and incidence of disease, in the west midlands: an epidemiological study Br J Sur 82 111 5
    • (1985) Br J sur , vol.82 , pp. 111-5
    • Bramhall, S.R.1    Allum, W.H.2    Jones, A.G.3
  • 5
    • 0025236629 scopus 로고
    • Survival after pancreaticoduodenectomy
    • M Trede G Schwal H Saeger 1990 Survival after pancreaticoduodenectomy Ann Surg 211 447 58
    • (1990) Ann Surg , vol.211 , pp. 447-58
    • Trede, M.1    Schwal, G.2    Saeger, H.3
  • 6
    • 58149309626 scopus 로고    scopus 로고
    • National Cancer Institute: Surveillance, Epidemiology, and End Results (SEER)*Stat 6.1 Database: Incidence-SEER 9 Regs Public Use, Bethesda, MD, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch. Nov 2004 Sub (1973-2002)
    • National Cancer Institute: Surveillance, Epidemiology, and End Results (SEER)*Stat 6.1 Database: Incidence-SEER 9 Regs Public Use, Bethesda, MD, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch. Nov 2004 Sub (1973-2002)
  • 7
    • 58149300983 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network (NCCN)
    • Practice Guidelines in Oncology. v.1. Fort Washington, PA.
    • National Comprehensive Cancer Network (NCCN). Pancreatic adenocarcinoma. Practice Guidelines in Oncology. v.1.2008. Fort Washington, PA. http://www.nccn.org/professionals/physician-gls/PDF/pancreatic.pdf
    • (2008) Pancreatic Adenocarcinoma
  • 8
    • 33748962008 scopus 로고    scopus 로고
    • Pancreatic resections after chemotherapy for locally advanced ductal adenocarcinoma: Analysis of perioperative outcome and survival
    • P Massuco L Capussotti A Magnino 2006 Pancreatic resections after chemotherapy for locally advanced ductal adenocarcinoma: analysis of perioperative outcome and survival Ann Surg Oncol 13 1201 8
    • (2006) Ann Surg Oncol , vol.13 , pp. 1201-8
    • Massuco, P.1    Capussotti, L.2    Magnino, A.3
  • 9
    • 31544438080 scopus 로고    scopus 로고
    • A Multi-institutional Phase II trial of preoperative full-dose gemcitabine and concurrent radiation for patients with potentially resectable pancreatic carcinoma
    • M Talamonti W Small M Mulcahy 2005 A Multi-institutional Phase II trial of preoperative full-dose gemcitabine and concurrent radiation for patients with potentially resectable pancreatic carcinoma Ann Surg Oncol 13 150 8
    • (2005) Ann Surg Oncol , vol.13 , pp. 150-8
    • Talamonti, M.1    Small, W.2    Mulcahy, M.3
  • 10
    • 0031056942 scopus 로고    scopus 로고
    • Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas
    • FR Spitz JL Abbruzzese JE Lee 1997 Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas J Clin Oncol 15 928 37
    • (1997) J Clin Oncol , vol.15 , pp. 928-37
    • Spitz, F.R.1    Abbruzzese, J.L.2    Lee, J.E.3
  • 11
    • 0031972708 scopus 로고    scopus 로고
    • Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: An Eastern Cooperative Oncology Group study
    • J Hoffman S Lipsitz T Pisansky 1998 Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: an Eastern Cooperative Oncology Group study J Clin Oncol 16 317 23
    • (1998) J Clin Oncol , vol.16 , pp. 317-23
    • Hoffman, J.1    Lipsitz, S.2    Pisansky, T.3
  • 12
    • 0019410935 scopus 로고
    • Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil
    • CG Moertel S Frytak RG Hahn 1981 Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil Cancer 48 1075 10
    • (1981) Cancer , vol.48 , pp. 1075-10
    • Moertel, C.G.1    Frytak, S.2    Hahn, R.G.3
  • 13
    • 0023722682 scopus 로고
    • Treatment of locally unresectable carcinoma of the pancreas: Comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone
    • Gastrointestinal Tumor Study Group
    • Gastrointestinal Tumor Study Group 1988 Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone J Natl Cancer Inst 80 751 5
    • (1988) J Natl Cancer Inst , vol.80 , pp. 751-5
  • 14
    • 0042835658 scopus 로고    scopus 로고
    • Surgical resection following radiation therapy with concurrent gemcitabine in patients with previously unresectable adenocarcinoma of the pancreas
    • JB Ammori LM Colletti MM Zalupski 2003 Surgical resection following radiation therapy with concurrent gemcitabine in patients with previously unresectable adenocarcinoma of the pancreas J Gastrointest Surg 7 766 72
    • (2003) J Gastrointest Surg , vol.7 , pp. 766-72
    • Ammori, J.B.1    Colletti, L.M.2    Zalupski, M.M.3
  • 15
    • 0034128217 scopus 로고    scopus 로고
    • Pancreatic carcinoma deemed unresectable at exploration may be resected for cure: An institutional experience
    • C Chao J Hoffman E Ross 2000 Pancreatic carcinoma deemed unresectable at exploration may be resected for cure: an institutional experience Am Surg 66 378 87
    • (2000) Am Surg , vol.66 , pp. 378-87
    • Chao, C.1    Hoffman, J.2    Ross, E.3
  • 16
    • 18244369036 scopus 로고    scopus 로고
    • Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas
    • RR White HI Hurwitz MA Morse 2001 Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas Ann Sur Oncol 8 758 65
    • (2001) Ann sur Oncol , vol.8 , pp. 758-65
    • White, R.R.1    Hurwitz, H.I.2    Morse, M.A.3
  • 17
    • 0036716558 scopus 로고    scopus 로고
    • Does neoadjuvant chemoradiation downstage locally advanced pancreatic cancer?
    • HJ Kim K Czischke MF Brennan 2002 Does neoadjuvant chemoradiation downstage locally advanced pancreatic cancer? J Gastrointest Surg 6 763 9
    • (2002) J Gastrointest Surg , vol.6 , pp. 763-9
    • Kim, H.J.1    Czischke, K.2    Brennan, M.F.3
  • 18
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
    • JD Berlin P Catalano JP Thomas 2002 Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297 J Clin Oncol 20 3270 5
    • (2002) J Clin Oncol , vol.20 , pp. 3270-5
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3
  • 19
    • 0141688333 scopus 로고    scopus 로고
    • Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • MJ Moore J Hamm J Dancey 2003 Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group J Clin Oncol 21 3296 302
    • (2003) J Clin Oncol , vol.21 , pp. 3296-302
    • Moore, M.J.1    Hamm, J.2    Dancey, J.3
  • 20
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • L Rocha M Green R Roche 2004 Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate J Clin Oncol 22 3776 83
    • (2004) J Clin Oncol , vol.22 , pp. 3776-83
    • Rocha, L.1    Green, M.2    Roche, R.3
  • 21
    • 0037100983 scopus 로고    scopus 로고
    • A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
    • SR Bramhall J Schultz J Nemunaitis 2002 A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer Br J Cancer 87 161 7
    • (2002) Br J Cancer , vol.87 , pp. 161-7
    • Bramhall, S.R.1    Schultz, J.2    Nemunaitis, J.3
  • 22
    • 58149283702 scopus 로고    scopus 로고
    • Marimastat Pancreatic Cancer Study Group. Marimastat as first-line therapy for patients with unresectable pancreatic cancer: A randomized trial
    • Bramhal SR, Rosemurgy A, Brown PD, Marimastat Pancreatic Cancer Study Group. Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trial. J Clin Oncol 2001; 19:3477-55
    • (2001) J Clin Oncol , vol.19 , pp. 3477-55
    • Bramhal, S.R.1    Rosemurgy, A.2    Brown, P.D.3
  • 23
    • 2342645506 scopus 로고    scopus 로고
    • Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
    • E Van Cutsem H van de Velde P Karase 2004 Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer J Clin Oncol 22 1430 8
    • (2004) J Clin Oncol , vol.22 , pp. 1430-8
    • Van Cutsem, E.1    Van De Velde, H.2    Karase, P.3
  • 24
    • 16444384413 scopus 로고    scopus 로고
    • A randomized phase III trial of DX-8951f (exatecan mesylate) and gemcitabine vs gemcitabine alone in advanced pancreatic cancer
    • 23:abstr 4006
    • O'Reilly EM, Abou-Alfa GK, Letorneau R, et al. A randomized phase III trial of DX-8951f (exatecan mesylate) and gemcitabine vs gemcitabine alone in advanced pancreatic cancer. Proc Am Soc Clin Oncol 2004; 23:abstr 4006
    • (2004) Proc Am Soc Clin Oncol
    • O'Reilly, E.M.1    Abou-Alfa, G.K.2    Letorneau, R.3
  • 25
    • 16444372799 scopus 로고    scopus 로고
    • A randomized phase III study comparing gemcitabine + pemetrexed versus gemcitabine in patients with locally advanced and metastatic pancreas cancer
    • 23:abstr 4007
    • Richards DA, Kindler HL, Oettle H, et al. A randomized phase III study comparing gemcitabine + pemetrexed versus gemcitabine in patients with locally advanced and metastatic pancreas cancer. Proc Am Soc Clin Oncol 2004; 23:abstr 4007
    • (2004) Proc Am Soc Clin Oncol
    • Richards, D.A.1    Kindler, H.L.2    Oettle, H.3
  • 26
    • 16444383237 scopus 로고    scopus 로고
    • GemOx (gemcitabine + oxaliplatin) versus Gem (gemcitabine) in non-resectable pancreatic adenocarcinoma: Final results of the GERCOR/GISCAD Intergroup phase III
    • 23:abstr 4008
    • Louvet C, Labianca R, Hammel P, et al. GemOx (gemcitabine + oxaliplatin) versus Gem (gemcitabine) in non-resectable pancreatic adenocarcinoma: final results of the GERCOR/GISCAD Intergroup phase III. Proc Am Soc Clin Oncol 2004; 23:abstr 4008
    • (2004) Proc Am Soc Clin Oncol
    • Louvet, C.1    Labianca, R.2    Hammel, P.3
  • 27
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • HA Burris MJ Moore J Anderson 1997 Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial J Clin Oncol 15 2403 13
    • (1997) J Clin Oncol , vol.15 , pp. 2403-13
    • Burris, H.A.1    Moore, M.J.2    Anderson, J.3
  • 28
    • 0029875635 scopus 로고    scopus 로고
    • Synergistic interaction between cisplatin and gemcitabine in vitro
    • A Bergman V van Ruiz Haperen G Veerman 1996 Synergistic interaction between cisplatin and gemcitabine in vitro Clin Cancer Res 2 521 30
    • (1996) Clin Cancer Res , vol.2 , pp. 521-30
    • Bergman, A.1    Van Ruiz Haperen, V.2    Veerman, G.3
  • 29
    • 0030005273 scopus 로고    scopus 로고
    • Radiosensitization of pancreatic cancer cells by 2′,-difluoro- 2′deoxycytidine
    • T Lawrence E Chang T Hahn 1996 Radiosensitization of pancreatic cancer cells by 2′,-difluoro-2′deoxycytidine Int J Radiat Oncol Biol Phys 34 867 72
    • (1996) Int J Radiat Oncol Biol Phys , vol.34 , pp. 867-72
    • Lawrence, T.1    Chang, E.2    Hahn, T.3
  • 30
    • 12844287650 scopus 로고    scopus 로고
    • Combined modality therapy of gemcitabine and radiation
    • B Pauwels A Korst F Lardon 2005 Combined modality therapy of gemcitabine and radiation Oncologist 10 34 51
    • (2005) Oncologist , vol.10 , pp. 34-51
    • Pauwels, B.1    Korst, A.2    Lardon, F.3
  • 31
    • 12144269022 scopus 로고    scopus 로고
    • Effect of chemoradiotherapy with gemcitabine and cisplatin on locoregional control in patients with primary inoperable pancreatic cancer
    • R Wilkowski M Thoma R Schauer 2004 Effect of chemoradiotherapy with gemcitabine and cisplatin on locoregional control in patients with primary inoperable pancreatic cancer World J Surg 28 1011 8
    • (2004) World J Surg , vol.28 , pp. 1011-8
    • Wilkowski, R.1    Thoma, M.2    Schauer, R.3
  • 32
    • 0038121455 scopus 로고    scopus 로고
    • Chemotherapy for advanced pancreatic cancer
    • DG Haller 2003 Chemotherapy for advanced pancreatic cancer Int J Radiat Oncol Biol Phys 56 16 23
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 16-23
    • Haller, D.G.1
  • 33
    • 0036125839 scopus 로고    scopus 로고
    • Gemcitabine based combination treatment of pancreatic cancer
    • V Heinemann 2002 Gemcitabine based combination treatment of pancreatic cancer Semin Oncol 29 25 35
    • (2002) Semin Oncol , vol.29 , pp. 25-35
    • Heinemann, V.1
  • 34
    • 19944409357 scopus 로고    scopus 로고
    • Gemcitabine versus cisplatin epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: A randomised controlled multicentre phase III trial
    • M Reni S Cordio C Milandri 2005 Gemcitabine versus cisplatin epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomised controlled multicentre phase III trial Lancet Oncol 6 369 76
    • (2005) Lancet Oncol , vol.6 , pp. 369-76
    • Reni, M.1    Cordio, S.2    Milandri, C.3
  • 35
    • 0018347080 scopus 로고
    • A multi-institutional comparative trial of radiation therapy alone and in combination with 5-FU for locally unresectable pancreatic cancer
    • Gastrointestinal Tumor Study Group
    • Gastrointestinal Tumor Study Group. A multi-institutional comparative trial of radiation therapy alone and in combination with 5-FU for locally unresectable pancreatic cancer. Am Surg 1979;189:205-11
    • (1979) Am Surg , vol.189 , pp. 205-11
  • 36
    • 0028120291 scopus 로고
    • Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum
    • L Cora L Coffman R Sher 1994 Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum Int J Radiat Oncol Biol Phys 30 161 7
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 161-7
    • Cora, L.1    Coffman, L.2    Sher, R.3
  • 37
    • 0032839353 scopus 로고    scopus 로고
    • Chemotherapy as preoperative treatment in locally advanced unresectable pancreatic cancer patients: Results of a feasibility study
    • E Bajetta M Di Bartolomeo SC Stani 1999 Chemotherapy as preoperative treatment in locally advanced unresectable pancreatic cancer patients: results of a feasibility study J Radiat Oncol Biol Phys 45 285 9
    • (1999) J Radiat Oncol Biol Phys , vol.45 , pp. 285-9
    • Bajetta, E.1    Di Bartolomeo, M.2    Stani, S.C.3
  • 38
    • 0027216212 scopus 로고
    • Neoadjuvant therapy for unresectable pancreatic adenocarcinoma
    • Jessup JM, Steele, Mayer RJ, et al. Neoadjuvant therapy for unresectable pancreatic adenocarcinoma. Arch Surg 1993; 128:559-64
    • (1993) Arch Surg , vol.128 , pp. 559-64
    • Jessup, J.M.1    Steele2    Mayer, R.J.3
  • 39
    • 0030742115 scopus 로고    scopus 로고
    • Combined modality therapy for stage II and stage III pancreatic carcinoma
    • AG Kamthan J Morris J Dalton 1997 Combined modality therapy for stage II and stage III pancreatic carcinoma J Clin Oncol 15 2920 7
    • (1997) J Clin Oncol , vol.15 , pp. 2920-7
    • Kamthan, A.G.1    Morris, J.2    Dalton, J.3
  • 40
    • 0026441565 scopus 로고
    • Difluorodeoxycytidine (dFDC)-gemcitabine: A phase i study
    • E Poplin T Corbett L Flaherty 1992 Difluorodeoxycytidine (dFDC)-gemcitabine: a phase I study Invest New Drugs 10 165 70
    • (1992) Invest New Drugs , vol.10 , pp. 165-70
    • Poplin, E.1    Corbett, T.2    Flaherty, L.3
  • 41
    • 8944261362 scopus 로고    scopus 로고
    • A phase II trial of gemcitabine in patients with 5-FU refractory pancreas cancer
    • M Rothenberg M Moore M Cripps 1996 A phase II trial of gemcitabine in patients with 5-FU refractory pancreas cancer Ann Oncol 7 347 53
    • (1996) Ann Oncol , vol.7 , pp. 347-53
    • Rothenberg, M.1    Moore, M.2    Cripps, M.3
  • 42
    • 0000046403 scopus 로고    scopus 로고
    • A phase i study of gemcitabine in combination with radiation therapy in patients with localized, unresectable pancreatic cancer
    • C McGinn D Smith C Ozark's 1998 A phase I study of gemcitabine in combination with radiation therapy in patients with localized, unresectable pancreatic cancer Proc ASCO 17 264a
    • (1998) Proc ASCO , vol.17
    • McGinn, C.1    Smith, D.2    Ozark'S, C.3
  • 43
    • 0035890443 scopus 로고    scopus 로고
    • A phase i trial of radiation dose escalation with concurrent weekly full dose gemcitabine in patients with advanced pancreatic cancer
    • C McGinn M Zalupski I Shureiqi 2001 A phase I trial of radiation dose escalation with concurrent weekly full dose gemcitabine in patients with advanced pancreatic cancer J Clin Oncol 19 4202 8
    • (2001) J Clin Oncol , vol.19 , pp. 4202-8
    • McGinn, C.1    Zalupski, M.2    Shureiqi, I.3
  • 44
    • 0035253713 scopus 로고    scopus 로고
    • Radiation concurrent with gemcitabine for locally advanced head and neck cancer: A phase i trial and intracellular drug incorporation study
    • A Eisbruch D Shewach C Bradford 2001 Radiation concurrent with gemcitabine for locally advanced head and neck cancer: a phase I trial and intracellular drug incorporation study J Clin Oncol 19 792 9
    • (2001) J Clin Oncol , vol.19 , pp. 792-9
    • Eisbruch, A.1    Shewach, D.2    Bradford, C.3
  • 45
    • 0026454511 scopus 로고
    • Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas
    • D Evans T Rich D Byrd 1992 Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas Arch Surg 127 1335 9
    • (1992) Arch Surg , vol.127 , pp. 1335-9
    • Evans, D.1    Rich, T.2    Byrd, D.3
  • 46
    • 0032421150 scopus 로고    scopus 로고
    • Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy and intraoperative radiation therapy for resectable pancreatic adenocarcinoma
    • PW Pisters JL Abbruzzese NA Janjan 1998 Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy and intraoperative radiation therapy for resectable pancreatic adenocarcinoma J Clin Oncol 16 3843 50
    • (1998) J Clin Oncol , vol.16 , pp. 3843-50
    • Pisters, P.W.1    Abbruzzese, J.L.2    Janjan, N.A.3
  • 47
    • 33749071359 scopus 로고    scopus 로고
    • O'Reilly EM. Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer
    • Abou-Alfa GK, Letourneau R, Harker G, et al. O'Reilly EM. Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer. J Clin Oncol 2006; 4:4441-7
    • (2006) J Clin Oncol , vol.4 , pp. 4441-7
    • Abou-Alfa, G.K.1    Letourneau, R.2    Harker, G.3
  • 48
    • 0027323902 scopus 로고
    • Neoadjuvant chemoradiation in pancreatic and duodenal carcinoma. A phase II study
    • R Yeung J Weese J Hoffman 1993 Neoadjuvant chemoradiation in pancreatic and duodenal carcinoma. A phase II study Cancer 72 2124 33
    • (1993) Cancer , vol.72 , pp. 2124-33
    • Yeung, R.1    Weese, J.2    Hoffman, J.3
  • 49
    • 0025650879 scopus 로고
    • Increased resectability of locally advanced pancreatic and periampullary carcinoma with neoadjuvant chemoradiotherapy
    • JL Weese ML Nussbaum AR Paul 1990 Increased resectability of locally advanced pancreatic and periampullary carcinoma with neoadjuvant chemoradiotherapy Int J Pancreatol 7 177 85
    • (1990) Int J Pancreatol , vol.7 , pp. 177-85
    • Weese, J.L.1    Nussbaum, M.L.2    Paul, A.R.3
  • 50
    • 0032986121 scopus 로고    scopus 로고
    • Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas
    • R White C Lee M Anscher 1999 Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas Ann Surg Oncol 6 38 45
    • (1999) Ann Surg Oncol , vol.6 , pp. 38-45
    • White, R.1    Lee, C.2    Anscher, M.3
  • 51
    • 33750446269 scopus 로고    scopus 로고
    • Locally advanced pancreatic adenocarcinoma. Chemoradiotherapy, reevaluation and secondary resection
    • JR Delpero O Turrini 2006 Locally advanced pancreatic adenocarcinoma. Chemoradiotherapy, reevaluation and secondary resection Cancer Radiother 10 462 70
    • (2006) Cancer Radiother , vol.10 , pp. 462-70
    • Delpero, J.R.1    Turrini, O.2
  • 52
    • 33645548634 scopus 로고    scopus 로고
    • Subsequent resection of locally advanced pancreatic carcinoma after chemoradiotherapy
    • X Adhoute D Smith V Vendrely 2006 Subsequent resection of locally advanced pancreatic carcinoma after chemoradiotherapy Gastroenterol Clin Biol 30 224 30
    • (2006) Gastroenterol Clin Biol , vol.30 , pp. 224-30
    • Adhoute, X.1    Smith, D.2    Vendrely, V.3
  • 53
    • 23944459082 scopus 로고    scopus 로고
    • Surgical resection after radiochemotherapy in patients with unresectable adenocarcinoma of the pancreas
    • A Sa Cunha A Rault C Laurent 2005 Surgical resection after radiochemotherapy in patients with unresectable adenocarcinoma of the pancreas Am Coll Surg 201 359 65
    • (2005) Am Coll Surg , vol.201 , pp. 359-65
    • Sa Cunha, A.1    Rault, A.2    Laurent, C.3
  • 54
    • 0033985637 scopus 로고    scopus 로고
    • Preoperative chemotherapy, radiotherapy, and surgical resection of locally advanced pancreatic cancer
    • HJ Wanebo AS Glicksman MP Vezeridis 2000 Preoperative chemotherapy, radiotherapy, and surgical resection of locally advanced pancreatic cancer Arch Surg 135 81 7
    • (2000) Arch Surg , vol.135 , pp. 81-7
    • Wanebo, H.J.1    Glicksman, A.S.2    Vezeridis, M.P.3
  • 55
    • 0346042991 scopus 로고    scopus 로고
    • Surgical therapy of locally advanced and primary inoperable pancreatic carcinoma after neoadjuvant preoperative radio chemotherapy
    • HG Rau MW Wichmann R Wilkowski 2002 Surgical therapy of locally advanced and primary inoperable pancreatic carcinoma after neoadjuvant preoperative radio chemotherapy Chirurg 73 132 7
    • (2002) Chirurg , vol.73 , pp. 132-7
    • Rau, H.G.1    Wichmann, M.W.2    Wilkowski, R.3
  • 56
    • 0037321150 scopus 로고    scopus 로고
    • Surgical resection after preoperative chemoradiotherapy benefits selected patients with unresectable pancreatic cancer
    • J Aristu R Canon F Pardo 2003 Surgical resection after preoperative chemoradiotherapy benefits selected patients with unresectable pancreatic cancer Am J Clin Oncol 26 30 6
    • (2003) Am J Clin Oncol , vol.26 , pp. 30-6
    • Aristu, J.1    Canon, R.2    Pardo, F.3
  • 57
    • 0036534672 scopus 로고    scopus 로고
    • Is the therapeutic index better with Gemcitabine-based chemoradiation than with 5-FU-based chemoradiation in LAPC?
    • CH Crane JL Abbruzzeze DB Evans 2002 Is the therapeutic index better with Gemcitabine-based chemoradiation than with 5-FU-based chemoradiation in LAPC? Int J Radiat Oncol Biol Phys 52 1293 302
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 1293-302
    • Crane, C.H.1    Abbruzzeze, J.L.2    Evans, D.B.3
  • 58
    • 4444220500 scopus 로고    scopus 로고
    • Neoadjuvant therapy for pancreatic cancer: The Duke experience
    • RR White DS Tyler 2004 Neoadjuvant therapy for pancreatic cancer: the Duke experience Surg Oncol Clin N Am 13 675 84
    • (2004) Surg Oncol Clin N Am , vol.13 , pp. 675-84
    • White, R.R.1    Tyler, D.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.