Pancreatic serous microcystic adenoma with extensive oncocytic change

Pathology International

Volumn 59, Issue 2, 2009, Pages 102-106

  Akiyama, Takashi ^a   Sadahira, Yoshito ^a   Irei, Isao ^a   Nishimura, Hirotake ^a   Hida, Akira I ^b   Notohara, Kenji ^c   Hamazaki, Shuji ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c KURASHIKI CENTRAL HOSPITAL   (Japan)

Author keywords

Oncocytic change; Pancreatic tumor; Serous microcystic adenoma

Indexed keywords

CYTOKERATIN 19; CYTOKERATIN 20; CYTOKERATIN 7; CYTOKERATIN 8; INHIBIN; MITOCHONDRION ANTIBODY; MUCIN 1; MUCIN 2; MUCIN 5AC; MUCIN 6; NEURON SPECIFIC ENOLASE;

AGED; ARTICLE; CASE REPORT; CELL STRUCTURE; COMPUTER ASSISTED TOMOGRAPHY; CYSTADENOMA; CYTOPATHOLOGY; CYTOPLASM; ECHOGRAPHY; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; EOSINOPHIL; FEMALE; GRANULAR CELL; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; PANCREAS ADENOMA; PANCREAS TUMOR; PANCREATIC SEROUS MICROCYSTIC ADENOMA; PANCREATICODUODENECTOMY; PERIODIC ACID SCHIFF STAIN; PHENOTYPE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; TREATMENT OUTCOME; TUMOR CELL; TUMOR VOLUME;

ADENOMA; ADENOMA, OXYPHILIC; AGED; AUTOANTIBODIES; CYTOPLASM; FEMALE; HUMANS; MITOCHONDRIA; OXYPHIL CELLS; PANCREATIC NEOPLASMS; PANCREATICODUODENECTOMY; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 58149308218     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2008.02336.x     Document Type: Article

References (23)

1. Capella C, Solcia E, Kloeppel G, Hruban RH. Serous cystic neoplasms of the pancreas. In : Hamilton SR, Aaltonen LA, eds. World Health Organization Classification of Tumours; Pathology and Genetics, Tumours of the Digestive System. Lyon : IARC Press, 2000 231 3.
2. Hruban RH, Pitman MB, Klimstra DS, eds. Tumors of the Pancreas. Atlas of Tumor Pathology, 4th series, fascicle 6. Washington, DC : Armed Forces Institute of Pathology, 2007.
3. Compton CC. Serous cystic tumors of the pancreas. Semin Diagn Pathol 2000 17 : 43 55.
4. Albores-Saavedra J, Gould EW, Angeles-Angeles A, Henson DE. Cystic tumors of the pancreas. Pathol Annu 1990 25 : 19 50.
5. Kim YI, Seo JW, Suh JS, Lee KU, Choe KJ. Microcystic adenomas of the pancreas. Report of three cases with two of multicentric origin. Am J Clin Pathol 1990 94 : 150 56.
6. Nappi O, Ferrara G, Wick MR. Neoplasms composed of eosinophilic polygonal cells: An overview with consideration of different cytomorphologic patterns. Semin Diagn Pathol 1999 16 : 82 90.
7. Paulino AF, Huvos AG. Oncocytic and oncocytoid tumors of the salivary glands. Semin Diagn Pathol 1999 16 : 98 104.
8. Reuter VE. Renal tumors exhibiting granular cytoplasm. Semin Diagn Pathol 1999 16 : 135 45.
9. Papotti M, Gugliotta P, Forte G, Bussolati G. Immunohistochemical identification of oxyphilic mitochondrion-rich cells. Appl Immunohistochem 1994 2 : 262 7.
10. Shintaku M, Honda T. Identification of oncocytic lesions of salivary glands by anti-mitochondrial immunohistochemistry. Histopathology 1997 31 : 408 11.
11. Papotti M, Cassoni P, Taraglio S, Bussolati G. Oncocytic and oncocytoid tumors of the exocrine pancreas, liver, and gastrointestinal tract. Semin Diagn Pathol 1999 16 : 126 34.
12. Volante M, La Rosa S, Castellano I, Finzi G, Capella C, Bussolati G. Clinico-pathological features of a series of 11 oncocytic endocrine tumours of the pancreas. Virchows Arch 2006 448 : 545 51.
13. Hussain S, Arwini A, Chetty R, Klimstra DS. Oncocytic pancreatic endocrine neoplasms: A clinicopathologic and immunohistochemical analysis of 21 cases. Mod Pathol 2005 18 : 279A.
14. Adsay NV, Adair CF, Heffess CS, Klimstra DS. Intraductal oncocytic papillary neoplasms of the pancreas. Am J Surg Pathol 1996 20 : 980 94.
15. Shima Y, Yagi T, Inagaki M et al. Intraductal oncocytic papillary neoplasm of the pancreas with celiac artery compression syndrome and a jejunal artery aneurysm: Report of a case. Surg Today 2005 35 : 86 90.
16. Albores-Saavedra J, Wu J, Crook T, Amirkhan RH, Jones L, Hruban RH. Intestinal and oncocytic variants of pancreatic intraepithelial neoplasia. A morphological and immunohistochemical study. Ann Diagn Pathol 2005 9 : 69 76.
17. Bartlett AS, Deo S, Oosthuysen W, Krishna G. Oncocytic mucinous cystadenoma of the pancreas. Pathology 2004 36 : 286 8.
18. Kosmahl M, Wagner J, Peters K, Sipos B, Klöppel G. Serous cystic neoplasms of the pancreas: An immunohistochemical analysis revealing alpha-inhibin, neuron-specific enolase, and MUC6 as new markers. Am J Surg Pathol 2004 28 : 339 46.
19. Yasuhara Y, Sakaida N, Uemura Y, Senzaki H, Shikata N, Tsubura A. Serous microcystic adenoma (glycogen-rich cystadenoma) of the pancreas: Study of 11 cases showing clinicopathological and immunohistochemical correlations. Pathol Int 2002 52 : 307 12.
20. Luttges J, Kloppel G. Differentiating pancreatic tumours by their mucin expression. Histopathology 2002 41 (Suppl. 2 267 94.
21. Adsay NV, Klimstra DS. Cystic forms of typically solid pancreatic tumors. Semin Diagn Pathol 2000 17 : 81 8.
22. Kosmahl M, Pauser U, Peters K et al. Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: A review of 418 cases and a classification proposal. Virchows Arch 2004 445 : 168 78.
23. Zamboni G, Terris B, Scarpa A et al. Acinar cell cystadenoma of the pancreas: A new entity? Am J Surg Pathol 2002 26 : 698 704.