Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation (European Journal of Nuclear Medicine and Molecular Imaging DOI: 10.1007/s00259-008-0834-x);Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 35, Issue 12, 2008, Pages 2203-2211

  Arlicot, Nicolas ^a,b,c   Katsifis, Andrew ^d   Garreau, Lucette ^a,b   Mattner, Filomena ^d   Vergote, Jackie ^a,b   Duval, Stéphanie ^a,b,c   Bodard, Sylvie ^a,b   Guilloteau, Denis ^a,b,c   Chalon, Sylvie ^a  

^a CHRU de Tours   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c UNIVERSITY HOSPITAL OF TOURS   (France)

^d AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

Author keywords

Excitotoxicity; Inflammation; Microglia; Peripheral benzodiazepine receptor; SPECT

Indexed keywords

6 CHLORO 2 (4' IODOPHENYL) 3 (N,N DIETHYL)IMIDAZO[1,2 A]PYRIDINE 3 ACETAMIDE; 6 CHLORO 2 (4' IODOPHENYL) 3 (N,N DIETHYL)IMIDAZO[1,2 A]PYRIDINE 3 ACETAMIDE I 125; BENZODIAZEPINE RECEPTOR; IODINE 125; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; PYRIDINE DERIVATIVE; QUINOLINIC ACID; TRACER; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN INJURY; BRAIN MITOCHONDRION; CELL ACTIVATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; EXCITOTOXICITY; INFLAMMATION; MALE; MICROGLIA; NONHUMAN; PROTEIN EXPRESSION; RADIOACTIVITY; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 58149305696     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-0882-2     Document Type: Erratum

References (41)

1. V Papadopoulos M Baraldi TR Guilarte TB Knudsen JJ Lacapère P Lindemann 2006 Translocator protein (18 kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function Trends Pharmacol Sci 27 402 9
2. MW McEnery AM Snowman RR Trifiletti SH Snyder 1992 Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier Proc Natl Acad Sci U S A 89 8 3170 4
3. N Jamin JM Neumann MA Ostuni TK Vu ZX Yao S Murail 2005 Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor Mol Endocrinol 19 588 94
4. JJ Lacapere V Papadopoulos 2003 Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis Steroids 68 569 85
5. AP Sutter K Maaser M Hopfner B Barthel P Grabowski S Faiss 2002 Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human oesophageal cancer cells Int J Cancer 102 4 318 27
6. 3H]PK11195, an isoquinoline carboxamide derivative: kinetic studies and autoradiographic localization J Neurochem 41 6 1744 50
7. 11C]PK11195 Neurology 55 7 1052 4
8. A Cagnin DJ Brooks AM Kennedy RN Gunn R Myers FE Turkheimer 2001 In-vivo measurement of activated microglia in dementia Lancet 358 9280 461 7
9. V Papadopoulos L Lecanu RC Brown Z Han ZX Yao 2006 Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders Neuroscience 138 3 749 56
10. RB Banati J Newcombe RN Gunn A Cagnin FE Turkheimer F Heppner 2000 The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity Brain 123 2321 37
11. K Messmer GP Reynolds 1998 Increased peripheral benzodiazepine binding sites in the brain of patients with Huntington's disease Neurosci Lett 241 1 53 6
12. 11C](R)-PK11195 positron emission tomography study Neurobiol Dis 15 3 601 9
13. J Benavides D Fage C Carter B Scatton 1987 Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage Brain Res 421 1-2 167 72
14. S Venneti BJ Lopresti CA Wiley 2006 The peripheral benzodiazepine receptor (translocator protein 18 kDa) in microglia: from pathology to imaging Prog Neurobiol 80 6 308 22
15. E Vowinckel D Reutens B Becher G Verge A Evans T Owens 1997 PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis J Neurosci Res 50 2 345 53
16. 123I]iodo-PK11195: a possible single-photon emission tomography tracer for visualization of inflammation Eur J Nucl Med 26 3 194 200
17. 11C]PK11195 and comparison of their behaviours as radioligands for PK binding sites in rats Nucl Med Biol 21 573 81
18. S Belloli RM Moresco M Matarrese G Biella F Sanvito P Simonelli 2004 Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo PET imaging of neurodegeneration Neurochem Int 44 6 433 40
19. 11C]PK11195 brain studies J Cereb Blood Flow Metab 25 7 842 51
20. 131I]iodo-5-methoxybenzyl) acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain J Med Chem 50 848 55
21. 11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation J Nucl Med 48 4 573 81
22. 11C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors Glia 55 1459 68
23. 11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies J Neurol Sci 229-230 219 23
24. 123I]-CLINDE: a radioiodinated imidazopyridine-3-acetamide for the study of peripheral benzodiazepine binding sites (PBBS) Eur J Nucl Med Mol Imaging 35 779 89
25. F Mattner A Katsifis M Staykova P Ballantyne DO Willenborg 2005 Evaluation of a radiolabelled peripheral benzodiazepine receptor ligand in the central nervous system inflammation of experimental autoimmune encephalomyelitis: a possible probe for imaging multiple sclerosis Eur J Nucl Med Mol Imaging 32 5 557 63
26. L Li M Fan CD Icton N Chen BR Leavitt MR Hayden 2003 Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington's disease Neurobiol Aging 24 8 1113 21
27. 123I]imidazo[1,2-a]pyridines as potential probes for the study of the peripheral benzodiazepine receptors using SPECT Radiochim Acta 88 3-4 229 32
28. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. New York: Academic; 1986.
29. AP Robinson TM White DW Mason 1986 Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies, MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3 Immunology 57 239 47
30. JK Ryu HB Choi JG Mc Larnon 2005 Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum Neurobiol Dis 20 550 61
31. S Chalon C Pellevoisin S Bodard MP Vilar JC Besnard D Guilloteau 1996 Iodinated PK-11195 as an ex vivo marker of neuronal injury in the lesioned rat brain Synapse 24 334 39
32. 18F]PK14105 as markers for neuronal damage J Neurochem 55 175 85
33. A Doble O Ferris MC Burgevin J Menager A Uzan MC Dubroeucq 1987 Photoaffinity labelling of peripheral-type benzodiazepine-binding sites Mol Pharmacol 31 42 49
34. R Schwarcz WO Whetsell Jr RM Mangano 1983 Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain Science 219 4582 316 8
35. MF Beal NW Kowall DW Ellison MF Mazurek KJ Swartz JB Martin 1986 Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid Nature 321 168 71
36. 123I]imidazo[1,2-a]pyridines as potential probes for the study of the peripheral benzodiazepine receptors using SPECT J Nucl Med 39 5 50
37. 123I]-CLINDE in animal tumour models J Lab Comp Radiopharm 46 S9
38. 123I]-labelled peripheral benzodiazepine receptor ligands in tumour bearing rodents Eur J Nucl Med Mol Imaging 29 S163
39. S Venneti BJ Lopresti G Wang SL Slagel NS Mason CA Mathis 2007 A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation J Neurochem 102 2118 31
40. ML James RR Fulton DJ Henderson S Eberl SR Meikle S Thomson 2005 Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand Bioorg Med Chem 13 22 6188 94
41. Y Fujimura Y Ikoma F Yasuno T Suhara M Ota R Matsumoto 2006 Quantitative analyses of 18F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain J Nucl Med 47 43 50