메뉴 건너뛰기




Volumn 32, Issue 1, 2009, Pages 57-65

Impact level of dihydrotestosterone on the hypothalamic-pituitary-leydig cell axis in men

Author keywords

Aromatase; Dihydrotestosterone; Gonadotroph cell; Leydig cell; Pituitary; Testis

Indexed keywords

ANDROSTANOLONE; AROMATASE; CHORIONIC GONADOTROPIN; ESTRADIOL; GLYCOPROTEIN; GONADOLIBERINE; GONADORELIN; LUTEINIZING HORMONE; NILUTAMIDE; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 58149299709     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2007.00818.x     Document Type: Article
Times cited : (12)

References (61)
  • 1
    • 0028157059 scopus 로고
    • The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol
    • Bagatell, C. J., Dahl, K. D. Bremner, W. J. (1994) The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol. Journal of Andrology 15, 15 21.
    • (1994) Journal of Andrology , vol.15 , pp. 15-21
    • Bagatell, C.J.1    Dahl, K.D.2    Bremner, W.J.3
  • 2
    • 0035884748 scopus 로고    scopus 로고
    • Successful percutaneous dihydrotestosterone treatment of gynecomastia occurring during highly active antiretroviral therapy: four cases and review of the literature
    • Benveniste, O., Simon, A. Herson, S. (2001) Successful percutaneous dihydrotestosterone treatment of gynecomastia occurring during highly active antiretroviral therapy: four cases and review of the literature. Clinical Infectious Diseases 35, 891 893.
    • (2001) Clinical Infectious Diseases , vol.35 , pp. 891-893
    • Benveniste, O.1    Simon, A.2    Herson, S.3
  • 4
    • 0018744454 scopus 로고
    • Endogenous opioids participate in the regulation of the hypothalamus-pituitary-luteinizing hormone axis and testosterone's negative feedback control of luteinizing hormone
    • Cicero, T. J., Schainker, B. A. Meyer, E. R. (1979) Endogenous opioids participate in the regulation of the hypothalamus-pituitary-luteinizing hormone axis and testosterone's negative feedback control of luteinizing hormone. Endocrinology 104, 1286 1291.
    • (1979) Endocrinology , vol.104 , pp. 1286-1291
    • Cicero, T.J.1    Schainker, B.A.2    Meyer, E.R.3
  • 5
    • 0020211729 scopus 로고
    • The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes
    • Clarke, I. J. Cummins, J. T. (1982) The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes. Endocrinology 111, 1737 1739.
    • (1982) Endocrinology , vol.111 , pp. 1737-1739
    • Clarke, I.J.1    Cummins, J.T.2
  • 6
    • 0025132717 scopus 로고
    • Aromatase activity in adult guinea pig brain is androgen dependent
    • Connolly, P. B., Roselli, C. E. Resko, J. A. (1990) Aromatase activity in adult guinea pig brain is androgen dependent. Biology of Reproduction 43, 698 703.
    • (1990) Biology of Reproduction , vol.43 , pp. 698-703
    • Connolly, P.B.1    Roselli, C.E.2    Resko, J.A.3
  • 7
    • 0017118924 scopus 로고
    • Selective effect of androgens on LH and FSH release in anterior pituitary cells in culture
    • Drouin, J. Labrie, F. (1976) Selective effect of androgens on LH and FSH release in anterior pituitary cells in culture. Endocrinology 98, 1528 1534.
    • (1976) Endocrinology , vol.98 , pp. 1528-1534
    • Drouin, J.1    Labrie, F.2
  • 8
    • 0016276909 scopus 로고
    • A highly sensitive in vitro bioassay for luteinizing hormone and chorionic gonadotropin: testosterone production by dispersed Leydig cells
    • Dufau, M. L., Mendelson, C. R. Catt, K. J. (1974) A highly sensitive in vitro bioassay for luteinizing hormone and chorionic gonadotropin: testosterone production by dispersed Leydig cells. Journal of Clinical Endocrinology and Metabolism 39, 610 613.
    • (1974) Journal of Clinical Endocrinology and Metabolism , vol.39 , pp. 610-613
    • Dufau, M.L.1    Mendelson, C.R.2    Catt, K.J.3
  • 9
    • 0025991345 scopus 로고
    • Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone-deficient men
    • Finkelstein, J. S., Whitcomb, R. W., O'Dea, L. S., Longcope, C., Schoenfeld, D. A. Crowley, W. F. Jr. (1991) Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone-deficient men. Journal of Clinical Endocrinology and Metabolism 73, 609 620.
    • (1991) Journal of Clinical Endocrinology and Metabolism , vol.73 , pp. 609-620
    • Finkelstein, J.S.1    Whitcomb, R.W.2    O'Dea, L.S.3    Longcope, C.4    Schoenfeld, D.A.5    Crowley Jr., W.F.6
  • 10
    • 0025955672 scopus 로고
    • Equine testicular aromatase: sunstrates specificity and kinetic characteristics
    • Gaillard, J. L. (1991) Equine testicular aromatase: sunstrates specificity and kinetic characteristics. Comparative Biochemistry and Physiology Part B 100, 107 115.
    • (1991) Comparative Biochemistry and Physiology Part B , vol.100 , pp. 107-115
    • Gaillard, J.L.1
  • 11
    • 0026035942 scopus 로고
    • Pharmacology of antiandrogens and value of combining androgen suppression with antiandrogen therapy
    • Gaillard-Moguilewsky, M. (1991) Pharmacology of antiandrogens and value of combining androgen suppression with antiandrogen therapy. Urology 37, 5 12.
    • (1991) Urology , vol.37 , pp. 5-12
    • Gaillard-Moguilewsky, M.1
  • 12
    • 0035912924 scopus 로고    scopus 로고
    • Regulation of the aromatase gene expression in mature rat Leydig cells
    • Genissel, C. Carreau, S. (2001) Regulation of the aromatase gene expression in mature rat Leydig cells. Molecular and Cellular Endocrinology 178, 141 146.
    • (2001) Molecular and Cellular Endocrinology , vol.178 , pp. 141-146
    • Genissel, C.1    Carreau, S.2
  • 13
    • 0023102423 scopus 로고
    • Sex steroids and pulsatile luteinizing hormone release in men. Studies in estrogen-treated agonadal subjects and eugonadal subjects treated with a novel nonsteroidal antiandrogen
    • Gooren, L., Spinder, T., Spijkstra, J. J., van Kessel, H., Smals, A., Rao, B. R. Hoogslag, M. (1987) Sex steroids and pulsatile luteinizing hormone release in men. Studies in estrogen-treated agonadal subjects and eugonadal subjects treated with a novel nonsteroidal antiandrogen. Journal of Clinical Endocrinology and Metabolism 64, 763 770.
    • (1987) Journal of Clinical Endocrinology and Metabolism , vol.64 , pp. 763-770
    • Gooren, L.1    Spinder, T.2    Spijkstra, J.J.3    Van Kessel, H.4    Smals, A.5    Rao, B.R.6    Hoogslag, M.7
  • 14
    • 0023198282 scopus 로고
    • Effect of estrogen on androgen receptor dynamics in female rat pituitary
    • Handa, R. J., Stadelman, H. L. Resko, J. A. (1987) Effect of estrogen on androgen receptor dynamics in female rat pituitary. Endocrinology 121, 84 89.
    • (1987) Endocrinology , vol.121 , pp. 84-89
    • Handa, R.J.1    Stadelman, H.L.2    Resko, J.A.3
  • 15
    • 0023140131 scopus 로고
    • Gonadal steroids modulate pulsatile luteinizing hormone secretion by perifused rat anterior pituitary cells
    • Kamel, F., Balz, J. A., Kubajak, C. L. Schneider, V. A. (1987) Gonadal steroids modulate pulsatile luteinizing hormone secretion by perifused rat anterior pituitary cells. Endocrinology 120, 1651 1657.
    • (1987) Endocrinology , vol.120 , pp. 1651-1657
    • Kamel, F.1    Balz, J.A.2    Kubajak, C.L.3    Schneider, V.A.4
  • 16
    • 0016430665 scopus 로고
    • Direct effect of testosterone and its 5-alpha-reduced metabolites on pituitary LH and FSH release in vitro: change in pituitary responsiveness to hypothalamic extract
    • Kao, L. W. Weisz, J. (1975) Direct effect of testosterone and its 5-alpha-reduced metabolites on pituitary LH and FSH release in vitro: change in pituitary responsiveness to hypothalamic extract. Endocrinology 96, 253 260.
    • (1975) Endocrinology , vol.96 , pp. 253-260
    • Kao, L.W.1    Weisz, J.2
  • 17
    • 0033305253 scopus 로고    scopus 로고
    • Regulation of luteinizing hormone secretion and subunit messenger ribonucleic acid expression by gonadal steroids in perifused pituitary cells from male monkeys and rats
    • Kawakami, S. Winters, S. J. (1999) Regulation of luteinizing hormone secretion and subunit messenger ribonucleic acid expression by gonadal steroids in perifused pituitary cells from male monkeys and rats. Endocrinology 140, 3587 3593.
    • (1999) Endocrinology , vol.140 , pp. 3587-3593
    • Kawakami, S.1    Winters, S.J.2
  • 19
    • 0015990923 scopus 로고
    • Studies on the nature of the hypothalamic estradiol-concentrating mechanism in the male and female rat
    • Korach, K. S. Muldoon, T. G. (1974) Studies on the nature of the hypothalamic estradiol-concentrating mechanism in the male and female rat. Endocrinology 94, 785 793.
    • (1974) Endocrinology , vol.94 , pp. 785-793
    • Korach, K.S.1    Muldoon, T.G.2
  • 20
    • 0020558791 scopus 로고
    • Studies on the treatment of idiopathic gynaecomastia with percutaneous dihydrotestosterone
    • Kuhn, J. M., Roca, R., Laudat, M. H., Rieu, M., Luton, J. P. Bricaire, H. (1983) Studies on the treatment of idiopathic gynaecomastia with percutaneous dihydrotestosterone. Clinical Endocrinology 19, 513 520.
    • (1983) Clinical Endocrinology , vol.19 , pp. 513-520
    • Kuhn, J.M.1    Roca, R.2    Laudat, M.H.3    Rieu, M.4    Luton, J.P.5    Bricaire, H.6
  • 22
    • 0024340648 scopus 로고
    • Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide)
    • Kuhn, J. M., Billebaud, T., Navratil, H., Moulonguet, A., Fiet, J., Grise, P. et al. (1989) Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide). New England Journal of Medicine 321, 413 418.
    • (1989) New England Journal of Medicine , vol.321 , pp. 413-418
    • Kuhn, J.M.1    Billebaud, T.2    Navratil, H.3    Moulonguet, A.4    Fiet, J.5    Grise, P.6
  • 23
    • 0028023252 scopus 로고
    • Evidence of oestradiol-induced changes in gonadotrophin secretion in men with feminizing Leydig cell tumours
    • Kuhn, J. M., Duranteau, L., Rieu, M. A., Lahlou, N., Roger, M. Luton, J. P. (1994) Evidence of oestradiol-induced changes in gonadotrophin secretion in men with feminizing Leydig cell tumours. European Journal of Endocrinology 131, 160 166.
    • (1994) European Journal of Endocrinology , vol.131 , pp. 160-166
    • Kuhn, J.M.1    Duranteau, L.2    Rieu, M.A.3    Lahlou, N.4    Roger, M.5    Luton, J.P.6
  • 24
    • 0023629798 scopus 로고
    • Gonadotropin and alpha-subunit secretion during long term pituitary suppression by D-Trp6-luteinizing hormone-releasing hormone microcapsules as treatment of precocious puberty
    • Lahlou, N., Roger, M., Chaussain, J. L., Feinstein, M. C., Sultan, C., Toublanc, J. E., Schally, A. V. Scholler, R. (1987) Gonadotropin and alpha-subunit secretion during long term pituitary suppression by D-Trp6-luteinizing hormone-releasing hormone microcapsules as treatment of precocious puberty. Journal of Clinical Endocrinology and Metabolism 65, 946 953.
    • (1987) Journal of Clinical Endocrinology and Metabolism , vol.65 , pp. 946-953
    • Lahlou, N.1    Roger, M.2    Chaussain, J.L.3    Feinstein, M.C.4    Sultan, C.5    Toublanc, J.E.6    Schally, A.V.7    Scholler, R.8
  • 25
    • 0025351486 scopus 로고
    • Estradiol alters the effectiveness of gonadotropin-releasing hormone (GnRH) in ovine pituitary cultures: GnRH receptors versus responsiveness to GnRH
    • Laws, S. C., Webster, J. C. Miller, W. L. (1990) Estradiol alters the effectiveness of gonadotropin-releasing hormone (GnRH) in ovine pituitary cultures: GnRH receptors versus responsiveness to GnRH. Endocrinology 127, 381 386.
    • (1990) Endocrinology , vol.127 , pp. 381-386
    • Laws, S.C.1    Webster, J.C.2    Miller, W.L.3
  • 26
    • 0020076317 scopus 로고
    • Testosterone inhibition of LRH-induced luteinizing hormone release by cultures of rat anterior pituitary cells: effect of inhibitors of steroid 5-alpha reductase
    • Leveque, N. W. Grotjean, H. E. Jr. (1982) Testosterone inhibition of LRH-induced luteinizing hormone release by cultures of rat anterior pituitary cells: effect of inhibitors of steroid 5-alpha reductase. Acta Endocrinologica 100, 196 205.
    • (1982) Acta Endocrinologica , vol.100 , pp. 196-205
    • Leveque, N.W.1    Grotjean Jr., H.E.2
  • 27
    • 0031788043 scopus 로고    scopus 로고
    • Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knock out mice
    • Lindzey, J., Wetsel, W. C., Couse, J. F., Stoker, T., Cooper, R. Korach, K. S. (1998) Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knock out mice. Endocrinolgy 139, 4092 4101.
    • (1998) Endocrinolgy , vol.139 , pp. 4092-4101
    • Lindzey, J.1    Wetsel, W.C.2    Couse, J.F.3    Stoker, T.4    Cooper, R.5    Korach, K.S.6
  • 28
    • 0020670503 scopus 로고
    • Selective inhibition of follicle-stimulating hormone secretion by estradiol. Mechanism for modulation of gonadotropin responses to low dose pulses of gonadotropin-releasing hormone
    • Marshall, J. C., Case, G. D., Valk, T. W., Corley, K. P., Sauder, S. E. Kelch, R. P. (1983) Selective inhibition of follicle-stimulating hormone secretion by estradiol. Mechanism for modulation of gonadotropin responses to low dose pulses of gonadotropin-releasing hormone. Journal of Clinical Investigation 71, 248 257.
    • (1983) Journal of Clinical Investigation , vol.71 , pp. 248-257
    • Marshall, J.C.1    Case, G.D.2    Valk, T.W.3    Corley, K.P.4    Sauder, S.E.5    Kelch, R.P.6
  • 29
    • 0020470292 scopus 로고
    • The 5-alpha-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications
    • Martini, L. (1982) The 5-alpha-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications. Endocrine Review 3, 1 25.
    • (1982) Endocrine Review , vol.3 , pp. 1-25
    • Martini, L.1
  • 30
    • 0015330192 scopus 로고
    • The transformation of testosterone into dihydrotestosterone by the brain and the anterior pituitary
    • Massa, R., Stupnicka, E., Kniewald, Z. Martini, L. (1972) The transformation of testosterone into dihydrotestosterone by the brain and the anterior pituitary. Journal of Steroid Biochemistry 3, 385 399.
    • (1972) Journal of Steroid Biochemistry , vol.3 , pp. 385-399
    • Massa, R.1    Stupnicka, E.2    Kniewald, Z.3    Martini, L.4
  • 31
    • 0016589524 scopus 로고
    • Conversion of testosterone into 5-alpha-reduced metabolites in the anterior pituitary and in the brain of maturing rats
    • Massa, R., Justo, S. Martini, L. (1975) Conversion of testosterone into 5-alpha-reduced metabolites in the anterior pituitary and in the brain of maturing rats. Journal of Steroid Biochemistry 6, 567 571.
    • (1975) Journal of Steroid Biochemistry , vol.6 , pp. 567-571
    • Massa, R.1    Justo, S.2    Martini, L.3
  • 33
    • 58149281461 scopus 로고
    • Receptors for testosterone and 5-alpha dihydrotestosterone in anterior pituitary and various areas of the brain
    • In: eds. P. Troen. R. Nankin. pp. Raven Press, New York.
    • Naess, O., Attramadal, A. Hansson, V. (1977) Receptors for testosterone and 5-alpha dihydrotestosterone in anterior pituitary and various areas of the brain. In : The Testis in Normal and Infertile (eds P. Troen R. Nankin pp. 227 241. Raven Press, New York.
    • (1977) The Testis in Normal and Infertile , pp. 227-241
    • Naess, O.1    Attramadal, A.2    Hansson, V.3
  • 34
    • 0014870432 scopus 로고
    • The binding affinity and specificity of the estrogen receptor of the rat uterus and anterior pituitary
    • Notides, A. C. (1970) The binding affinity and specificity of the estrogen receptor of the rat uterus and anterior pituitary. Endocrinology 87, 987 992.
    • (1970) Endocrinology , vol.87 , pp. 987-992
    • Notides, A.C.1
  • 36
    • 0022668004 scopus 로고
    • Gonadal regulation of hypothalamic gonadotropin-releasing hormone release in primates
    • Plant, T. M. (1986) Gonadal regulation of hypothalamic gonadotropin-releasing hormone release in primates. Endocrine Review 7, 75 88.
    • (1986) Endocrine Review , vol.7 , pp. 75-88
    • Plant, T.M.1
  • 38
    • 0014990488 scopus 로고
    • Steroid hormone metabolism in responsive tissues in vitro
    • Robel, P. (1971) Steroid hormone metabolism in responsive tissues in vitro. Acta Endocrinologica 153, 279 294.
    • (1971) Acta Endocrinologica , vol.153 , pp. 279-294
    • Robel, P.1
  • 39
    • 0026085458 scopus 로고
    • Synergistic induction of aromatase activity in the rat brain by estradiol and 5 alpha-dihydrotestosterone
    • Roselli, C. E. (1991) Synergistic induction of aromatase activity in the rat brain by estradiol and 5 alpha-dihydrotestosterone. Neuroendocrinology 53, 79 84.
    • (1991) Neuroendocrinology , vol.53 , pp. 79-84
    • Roselli, C.E.1
  • 41
    • 0016819440 scopus 로고
    • Is aromatization of testosterone to estradiol required for inhibition of luteinizing hormone secretion in men?
    • Santen, R. J. (1975) Is aromatization of testosterone to estradiol required for inhibition of luteinizing hormone secretion in men? Journal of Clinical Investigation 56, 1555 1563.
    • (1975) Journal of Clinical Investigation , vol.56 , pp. 1555-1563
    • Santen, R.J.1
  • 42
    • 0018147834 scopus 로고
    • Effect of chronic administration of estrogen, androgen, or both on serum levels of gonadotropins in adult men
    • Sawin, C. T., Ryan, R. J., Longcope, C. Fisher, L. E. (1978) Effect of chronic administration of estrogen, androgen, or both on serum levels of gonadotropins in adult men. Journal of Clinical Endocrinology and Metabolism 46, 911 915.
    • (1978) Journal of Clinical Endocrinology and Metabolism , vol.46 , pp. 911-915
    • Sawin, C.T.1    Ryan, R.J.2    Longcope, C.3    Fisher, L.E.4
  • 43
    • 0024476707 scopus 로고
    • Testosterone administration inhibits gonadotropin secretion by an effect directly on the human pituitary
    • Sheckter, C. B., Matsumoto, A. M. Bremner, W. J. (1989) Testosterone administration inhibits gonadotropin secretion by an effect directly on the human pituitary. Journal of Clinical Endocrinology and Metabolism 68, 397 401.
    • (1989) Journal of Clinical Endocrinology and Metabolism , vol.68 , pp. 397-401
    • Sheckter, C.B.1    Matsumoto, A.M.2    Bremner, W.J.3
  • 44
    • 0018825880 scopus 로고
    • Modulation of serum and pituitary luteinizing hormone bioactivity by androgen in the rat
    • Solano, A. R., Garcia-Vela, A., Catt, K. J. Dufau, M. L. (1980) Modulation of serum and pituitary luteinizing hormone bioactivity by androgen in the rat. Endocrinology 106, 1941 1948.
    • (1980) Endocrinology , vol.106 , pp. 1941-1948
    • Solano, A.R.1    Garcia-Vela, A.2    Catt, K.J.3    Dufau, M.L.4
  • 45
    • 0023836828 scopus 로고
    • Divergent effects of the antiestrogen tamoxifen and of estrogens on luteinizing hormone (LH) pulse frequency, but not on basal LH levels and LH pulse amplitude in men
    • Spijkstra, J. J., Spinder, T., Gooren, L. van Kessel, H. (1988) Divergent effects of the antiestrogen tamoxifen and of estrogens on luteinizing hormone (LH) pulse frequency, but not on basal LH levels and LH pulse amplitude in men. Journal of Clinical Endocrinology and Metabolism 66, 355 360.
    • (1988) Journal of Clinical Endocrinology and Metabolism , vol.66 , pp. 355-360
    • Spijkstra, J.J.1    Spinder, T.2    Gooren, L.3    Van Kessel, H.4
  • 46
    • 0032454317 scopus 로고    scopus 로고
    • Dihydrotestosterone: a rationale for its use as a non aromatizable androgen replacement therapeutic agent
    • Swerloff, R. S. Wang, C. C. (1998) Dihydrotestosterone: a rationale for its use as a non aromatizable androgen replacement therapeutic agent. Baillieres Clinical Endocrinology and Metabolism 12, 501 506.
    • (1998) Baillieres Clinical Endocrinology and Metabolism , vol.12 , pp. 501-506
    • Swerloff, R.S.1    Wang, C.C.2
  • 47
    • 0024306101 scopus 로고
    • Regulation of pro-gonadotropin-releasing hormone gene expression by sex steroids in the brain of male and female rats
    • Toranzo, D., Dupont, E., Simard, J., Labrie, C., Couet, J., Labrie, F. Pelletier, G. (1989) Regulation of pro-gonadotropin-releasing hormone gene expression by sex steroids in the brain of male and female rats. Molecular Endocrinology 3, 1748 1756.
    • (1989) Molecular Endocrinology , vol.3 , pp. 1748-1756
    • Toranzo, D.1    Dupont, E.2    Simard, J.3    Labrie, C.4    Couet, J.5    Labrie, F.6    Pelletier, G.7
  • 49
    • 0022447036 scopus 로고
    • Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection
    • Veldhuis, J. D. Johnson, M. L. (1986) Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection. American Journal of Physiology 250, E486 E493.
    • (1986) American Journal of Physiology , vol.250
    • Veldhuis, J.D.1    Johnson, M.L.2
  • 50
    • 0021259167 scopus 로고
    • Role of endogenous opiates in the expression of negative feedback actions of androgen and estrogen on pulsatile properties of luteinizing hormone secretion in man
    • Veldhuis, J. D., Rogol, A. D., Samojlik, E. Ertel, N. H. (1984) Role of endogenous opiates in the expression of negative feedback actions of androgen and estrogen on pulsatile properties of luteinizing hormone secretion in man. Journal of Clinical Investigation 74, 47 55.
    • (1984) Journal of Clinical Investigation , vol.74 , pp. 47-55
    • Veldhuis, J.D.1    Rogol, A.D.2    Samojlik, E.3    Ertel, N.H.4
  • 51
    • 0023256401 scopus 로고
    • Preferential release of bioactive luteinizing hormone in response to endogenous and low dose exogenous gonadotropin-releasing hormone pulses in man
    • Veldhuis, J. D., Johnson, M. L. Dufau, M. L. (1987) Preferential release of bioactive luteinizing hormone in response to endogenous and low dose exogenous gonadotropin-releasing hormone pulses in man. Journal of Clinical Endocrinology and Metabolism 64, 1275 1282.
    • (1987) Journal of Clinical Endocrinology and Metabolism , vol.64 , pp. 1275-1282
    • Veldhuis, J.D.1    Johnson, M.L.2    Dufau, M.L.3
  • 53
    • 0026682730 scopus 로고
    • Evidence that androgen negative feedback regulates hypothalamic gonadotropin-releasing hormone impulse strength and the burst-like secretion of biologically active luteinizing hormone in men
    • Veldhuis, J. D., Urban, R. J. Dufau, M. L. (1992) Evidence that androgen negative feedback regulates hypothalamic gonadotropin-releasing hormone impulse strength and the burst-like secretion of biologically active luteinizing hormone in men. Journal of Clinical Endocrinology and Metabolism 74, 1227 1235.
    • (1992) Journal of Clinical Endocrinology and Metabolism , vol.74 , pp. 1227-1235
    • Veldhuis, J.D.1    Urban, R.J.2    Dufau, M.L.3
  • 54
    • 0017123584 scopus 로고
    • Effects of fluoxymesterone on pituitary gonadal axis: the role of testosterone-estradiol-binging globulin
    • Virgesky, R., Easley, R. B. Loriaux, D. L. (1976) Effects of fluoxymesterone on pituitary gonadal axis: the role of testosterone-estradiol- binging globulin. Journal of Clinical Endocrinology and Metabolism 43, 1 9.
    • (1976) Journal of Clinical Endocrinology and Metabolism , vol.43 , pp. 1-9
    • Virgesky, R.1    Easley, R.B.2    Loriaux, D.L.3
  • 55
    • 0025239697 scopus 로고
    • Divergent responses of gonadotropin subunit messenger RNAs to continuous versus pulsatile gonadotropin-releasing hormone in vitro
    • Weiss, J., Jameson, J. L., Burrin, J. M. Crowley, W. F. Jr. (1990) Divergent responses of gonadotropin subunit messenger RNAs to continuous versus pulsatile gonadotropin-releasing hormone in vitro. Molecular Endocrinology 4, 557 564.
    • (1990) Molecular Endocrinology , vol.4 , pp. 557-564
    • Weiss, J.1    Jameson, J.L.2    Burrin, J.M.3    Crowley Jr., W.F.4
  • 56
    • 0033400405 scopus 로고    scopus 로고
    • Steroid feedback on gonadotropin release and pituitary gonadotropin subunit mRNA in mice lacking a functional estrogen receptor alpha
    • Wersinger, S. R., Haisenleder, D. J., Lubahn, D. B. Rissman, E. F. (1999) Steroid feedback on gonadotropin release and pituitary gonadotropin subunit mRNA in mice lacking a functional estrogen receptor alpha. Endocrine 11, 137 143.
    • (1999) Endocrine , vol.11 , pp. 137-143
    • Wersinger, S.R.1    Haisenleder, D.J.2    Lubahn, D.B.3    Rissman, E.F.4
  • 57
    • 0025376242 scopus 로고
    • Utility of free alpha-subunit as an alternative neuroendocrine marker of gonadotropin-releasing hormone (GnRH) stimulation of the gonadotroph in the human: evidence from normal and GnRH-deficient men
    • Whitcomb, R. W., O'Dea, L. S., Finkelstein, J. S., Heavern, D. M. Crowley, W. F. Jr. (1990) Utility of free alpha-subunit as an alternative neuroendocrine marker of gonadotropin-releasing hormone (GnRH) stimulation of the gonadotroph in the human: evidence from normal and GnRH-deficient men. Journal of Clinical Endocrinology and Metabolism 70, 1654 1661.
    • (1990) Journal of Clinical Endocrinology and Metabolism , vol.70 , pp. 1654-1661
    • Whitcomb, R.W.1    O'Dea, L.S.2    Finkelstein, J.S.3    Heavern, D.M.4    Crowley Jr., W.F.5
  • 58
    • 0019451437 scopus 로고
    • Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey
    • Wildt, L., Hausler, A., Marshall, G., Hutchison, J. S., Plant, T. M., Belchetz, P. E. Knobil, E. (1981) Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey. Endocrinology 109, 376 385.
    • (1981) Endocrinology , vol.109 , pp. 376-385
    • Wildt, L.1    Hausler, A.2    Marshall, G.3    Hutchison, J.S.4    Plant, T.M.5    Belchetz, P.E.6    Knobil, E.7
  • 59
    • 0023837536 scopus 로고
    • Alpha-subunit secretion in men with idiopathic hypogonadotropic hypogonadism
    • Winters, S. J. Troen, P. (1988) Alpha-subunit secretion in men with idiopathic hypogonadotropic hypogonadism. Journal of Clinical Endocrinology and Metabolism 66, 338 342.
    • (1988) Journal of Clinical Endocrinology and Metabolism , vol.66 , pp. 338-342
    • Winters, S.J.1    Troen, P.2
  • 60
    • 0018741213 scopus 로고
    • Studies on the role of sex steroids in the feedback control of gonadotropin concentrations in men. II. Use of the estrogen antagonist, clomiphene citrate
    • Winters, S. J., Janick, J. J., Loriaux, D. L. Sherins, R. J. (1979) Studies on the role of sex steroids in the feedback control of gonadotropin concentrations in men. II. Use of the estrogen antagonist, clomiphene citrate. Journal of Clinical Endocrinology and Metabolism 48, 222 227.
    • (1979) Journal of Clinical Endocrinology and Metabolism , vol.48 , pp. 222-227
    • Winters, S.J.1    Janick, J.J.2    Loriaux, D.L.3    Sherins, R.J.4
  • 61
    • 0026509650 scopus 로고
    • Effects of testosterone on gonadotropin subunit messenger ribonucleic acids in the presence or absence of gonadotropin-releasing hormone
    • Winters, S. J., Ishizaka, K., Kitahara, S., Troen, P. Attardi, B. (1992) Effects of testosterone on gonadotropin subunit messenger ribonucleic acids in the presence or absence of gonadotropin-releasing hormone. Endocrinology 130, 726 734.
    • (1992) Endocrinology , vol.130 , pp. 726-734
    • Winters, S.J.1    Ishizaka, K.2    Kitahara, S.3    Troen, P.4    Attardi, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.