The influence of LTS-4, a saponoside from Lysimachia thyrsiflora L., on human skin fibroblasts and human melanoma cells

Cellular and Molecular Biology Letters

Volumn 13, Issue 4, 2008, Pages 585-598

  Galanty, Agnieszka ^a   Michalik, Marta ^a   Sędek, Łukasz ^a   Podolak, Irma ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Cytotoxicity; Fibroblasts; Lysimachia thyrsiflora L.; Melanoma; Triterpene saponoside

Indexed keywords

3 0 [BETA DEXTRO XYLOPYRANOSYL(1-2)BETA DEXTRO GLUCOPYRANOSYL (1-4)[BETA DEXTRO GLUCOPYRANOSYL(1-2)]ALPHA LEVO ARABINOPYRANOSYL]CYCLAMIRETIN A; ACTIN; SAPONIN DERIVATIVE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; 3 O (BETA D XYLOPYRANOSYL (1 2) BETA D GLUCOPYRANOSYL (1 4) (BETA D GLUCOPYRANOSYL (1 2)) ALPHA L ARABINOPYRANOSYL)CYCLAMIRETIN A; 3-O-(BETA-D-XYLOPYRANOSYL-(1-2)-BETA-D-GLUCOPYRANOSYL-(1-4)-(BETA-D-GLUCOPYRANOSYL-(1-2))-ALPHA-L-ARABINOPYRANOSYL)CYCLAMIRETIN A; DRUG DERIVATIVE; OLEANOLIC ACID; SAPONIN;

ARTICLE; CELL GROWTH; CELL MOTILITY; CELL PROLIFERATION; CELL STRUCTURE; CELL TYPE; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG ISOLATION; HUMAN; HUMAN CELL; MELANOMA CELL; SKIN FIBROBLAST; ANIMAL; CELL CULTURE; CELL SHAPE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; CYTOSKELETON; DRUG EFFECT; FIBROBLAST; MELANOMA; METABOLISM; PRIMULACEAE; SKIN;

LYSIMACHIA THYRSIFLORA;

ANIMALS; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CELLS, CULTURED; CYTOSKELETON; FIBROBLASTS; HUMANS; MELANOMA; OLEANOLIC ACID; PRIMULACEAE; SAPONINS; SKIN;

EID: 58149296253     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-008-0013-x     Document Type: Article

References (27)

1. Xiao, K., Yi, Y.H., Wang, Z.Z., Tang, H.F., Li, Y.Q. and Lin, H.W. A cytotoxic triterpene saponin from the root bark of Aralia dasyphylla. J. Nat. Prod. 62 (1999) 1030-1032. (Pubitemid 29357459)
2. Barthomeuf, C., Debiton, E., Mshvildadze, V., Kemertelidze, E. and Balansard, G. In vitro activity of hederacolchisid A1 compared with other saponins from Hedera colchica against proliferation of human carcinoma and melanoma cells. Planta Med. 68 (2002) 672-675. (Pubitemid 35013374)
3. Marquina, S., Maldonado, N., Garduno-Ramirez, M.L., Aranda, E., Villarreal, M.L., Navarro, V., Bye, R., Delgado, G. and Alvarez, L. Bioactive oleanolic acid saponins and other constituents from the roots of Viguiera decurrens. Phytochemistry 56 (2001) 93-97. (Pubitemid 32059910)
4. rd International Symposium on Natural Drugs Proceedings, Naples, 2003, 199-200.
5. Karpova, V.I., Kintya, P.K. and Chirva, V.Y. Structure of saponin A from Naumburgia thyrsiflora. Khim. Prir. Soedin. 11 (1975) 364-366.
6. Kintya, P.K., Karpova, V.I. and Chirva, V.Y. Saponin from Naumburgia thyrsiflora. Khim. Prir. Soedin. 11 (1985) 520-521.
7. Yasukawa, K., Taira, T. and Takido, M. Flavonol gycosides from Lysimachia thyrsiflora. Biochem. Syst. Ecol. 25 (1997) 73-74.
8. Podolak, I., Janeczko, Z., Galanty, A., Michalik, M. and Trojanowska, D. A triterpene saponin from Lysimachia thyrsiflora L. Acta Pol. Pharm. - Drug Res. 64 (2007) 39-43. (Pubitemid 351360440)
9. Drukała, J., Rajwa, B. and Pietrzkowski, Z. Effect of daunomycin on expression of CD44H protein in HTB140 melanoma cells in vitro. Anticancer Res. 21 (2001) 3793-3798. (Pubitemid 34229243)
10. Szydłowska, H., Zaporowska, E., Kuszlik-Jochym, K., Korohoda, W. and Branny, J. Membranolytic activity of detergents as studied with cell viability tests. Folia Histochem. Cytochem. 16 (1978) 69-78. (Pubitemid 8361191)
11. Korohoda, W. and Madeja, Z. Contact of sarcoma cells with aligned fibroblasts accelerates their displacement, computer assisted analysis of tumour cell locomotion in co-culture. Biochem. Cell. Biol. 75 (1997) 263-276. (Pubitemid 127733152)
12. Friedl, P., Noble, P.B. and Zänker, K.S. Lymphocyte locomotion in three dimensional collagen gels. Comparison of three quantitative methods for analysis cell trajectories. J. Immunol. Methods 165 (1993) 157-165. (Pubitemid 23316402)
13. Sroka, J., Madeja, Z., Galanty, A., Michalik, M., Przestalski, S., Rakoczy, L. and Korohoda, W. Trimethyltin inhibits the chemotaxis of Dictyostelium discoideum amoebae. Europ. J. Protistol. 37 (2001) 313-326. (Pubitemid 33622366)
14. Sroka, J., Kamiński, R., Michalik, M., Madeja, Z., Przestalski, S. and Korohoda, W. The effect of triethyllead on the motile activity of walker 256 carcinosarcoma cells. Cell. Mol. Biol. Lett. 9 (2004) 15-30. (Pubitemid 38560194)
15. Seeman, P., Cheng, D. and Iles, G.H. Structure of membrane holes in osmotic and saponin hemolysis. J. Cell. Biol. 56 (1974) 519-527.
16. Shany, S., Bernheimer, A.W., Grushoff, P.S. and Kim, K.S. Evidence for membrane cholesterol as common binding site for cereolysin, streptolysin O and saponin. Mol. Cell. Biochem. 3 (1974) 179-186.
17. Galeotti, T., Borello, S., Minotti, G. and Masotti, L. Membrane alternations in cancer cells: the role of oxy radicals. Ann. NY Acad. Sci. 488 (1986) 468-480. (Pubitemid 18123380)
18. Tugnoli, V., Trinchero, A. and Tosi, M.R. Evaluation of the lipid composition of human healthy and neoplastic renal tissues. Ital. J. Biochem. 53 (2004) 169-182.
19. Pierzchalska, M., Michalik, M., Stȩpień, E. and Korohoda, W. Changes in morphology of human skin fibroblasts induced by local anaesthetics: role of actomyosin contraction. Eur. J. Pharm. 358 (1998) 235-244. (Pubitemid 28499217)
20. Michalik, M., Pierzchalska, M., Pabiańczyk-Kulka, A. and Korohoda, W. Procaine-induced enhancement of fluid-phase endocytosis and inhibition of exocytosis in human skin fibroblasts. Eur. J. Pharm. 475 (2003) 1-10. (Pubitemid 37088000)
21. Pollard, T.D. and Cooper, J.A. Actin and actin-binding proteins: a critical evaluation of mechanisms and functions. Annu. Rev. Biochem. 55 (1986) 987-1035.
22. Osborn, M., Born, T., Koitsch, H.J. and Weber, K. Stereo immunofluorescence microscopy: I. Three-dimensional arrangement of microfilaments, microtubules and tonofilaments. Cell 14 (1978) 477-488. (Pubitemid 9190228)
23. Buendia, B., Bre, M.-H. and Karsenti, E. Cytoskeletal control of centrioles movement during the establishment of polarity in Madin-Darby canine kidney cells. J. Cell. Biol. 110 (1990) 1123-1135. (Pubitemid 20136490)
24. Baumann, E., Stoya, G., Völkner, A., Richter, W., Lemke, C. and Linss, W. Hemolysis of human erythrocytes with saponin affects the membrane structure. Acta Histochem. 102 (2000) 21-35. (Pubitemid 30120643)
25. Shinkai, K., Akedo, H., Mukai, M., Imamura, F., Isoai, A., Kobayashi, M. and Kitagawa, I. Inhibition of in vitro tumor cell invasion by ginsenoside Rg3. Jpn. J. Cancer Res. 87 (1996) 357-362. (Pubitemid 26147848)
26. Wakabayashi, C., Hasegawa, H., Murata, J. and Saiki, I. In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res. 9 (1997) 411-417. (Pubitemid 127825994)
27. Wei-Wei, Ch., Chia-Yu, Y., Tzu-Wen, L., Peng-Hui, W. and Ying-Chieh, T. Soyasaponin I decreases the expression of α2,3-linked sialic acid on the cell surface and supresses the metastatic potential of B16F10 melanoma cells. Biochem. Biophys. Res. Commun. 341 (2006) 614-619.