Association between increased body mass index, calcineurin inhibitor use, and renal graft survival

Experimental and Clinical Transplantation

Volumn 6, Issue 3, 2008, Pages 199-202

  Ghahramani, Nasrollah ^a   Brian Reeves, W ^a   Hollenbeak, Christopher ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Kidney; Rejection; Transplant; Weight

Indexed keywords

CALCINEURIN;

ARTICLE; BODY MASS; BODY WEIGHT; COHORT ANALYSIS; DRUG ANTAGONISM; GRAFT SURVIVAL; HUMAN; KIDNEY TRANSPLANTATION; MORBID OBESITY; MORTALITY; OBESITY; PATIENT SELECTION; PHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; REFERENCE VALUE; RETROSPECTIVE STUDY; RISK; SURVIVAL; UNITED STATES; WEIGHT REDUCTION;

BODY MASS INDEX; CALCINEURIN; COHORT STUDIES; GRAFT SURVIVAL; HUMANS; KIDNEY TRANSPLANTATION; OBESITY; OBESITY, MORBID; ODDS RATIO; PATIENT SELECTION; PROPORTIONAL HAZARDS MODELS; REFERENCE VALUES; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; THINNESS; UNITED STATES; WEIGHT LOSS;

EID: 58149291731     PISSN: 13040855     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Stengel B, Tarver-Carr ME, Powe NR, Eberhardt MS, Brancati FL. Lifestyle factors, obesity and the risk of chronic kidney disease. Epidemiology. 2003 Jul;14(4):479-487.
2. McGovern MP, Fox TS, Xie H, Drake RE. A survey of clinical practices and readiness to adopt evidence-based practices: Dissemination research in an addiction treatment system. J Subst Abuse Treat. 2004;26(4):305-312.
3. Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Ann Intern Med. 2006;144(1):21-28.
4. Cofan F, Vela E, Cleries M. Obesity in renal transplantation: analysis of 2691 patients. Transplant Proc. 2005;37(9):3695-3697.
5. Friedman AN, Miskulin DC, Rosenberg IH, Levey AS. Demographics and trends in overweight and obesity in patients at time of kidney transplantation. Am J Kidney Dis. 2003;41(2):480-487.
6. Johnson DW, Isbel NM, Brown AM, et al. The effect of obesity on renal transplant outcomes. Transplantation. 2002;74(5):675-681.
7. Massarweh NN, Clayton JL, Mangum CA, Florman SS, Slakey DP. High body mass index and short- and long-term renal allograft survival in adults. Transplantation. 2005;80(10):1430-1434.
8. Armstrong KA, Campbell SB, Hawley CM, Nicol DL, Johnson DW, Isbel NM. Obesity is associated with worsening cardiovascular risk factor profiles and proteinuria progression in renal transplant recipients. Am J Transplant. 2005;5(11):2710-2718.
9. Gore JL, Pham PT, Danovitch GM, Wilkinson AH, Rosenthal JT, Lipshutz GS, et al. Obesity and outcome following renal transplantation. Am J Transplant. 2006;6(2):357-363.
10. Meier-Kriesche HU, Arndorfer JA, Kaplan B. The impact of body mass index on renal transplant outcomes: a significant independent risk factor for graft failure and patient death. Transplantation. 2002;73(1):70-74.
11. Raiss-Jalali GA, Mehdizadeh AR, Razmkon A, et al. Effect of body mass index at time of transplantation and weight gain after transplantation on allograft function in kidney transplant recipients in Shiraz. Transplant Proc. 2005;37(7):2998-3000.
12. Chang SH, Coates PT, McDonald SP. Effects of body mass index at transplant on outcomes of kidney transplantation. Transplantation. 2007;84(8):981-987.
13. Ribstein J, du Cailar G, Mimran A. Combined renal effects of overweight and hypertension. Hypertension. 1995;26(4):610-615.
14. Chagnac A, Weinstein T, Korzets A, Ramadan E, Hirsch J, Gafter U. Glomerular hemodynamics in severe obesity. Am J Physiol Renal Physiol. 2000;278(5):F817-822.
15. Henegar JR, Bigler SA, Henegar LK, Tyagi SC, Hall JE. Functional and structural changes in the kidney in the early stages of obesity. J Am Soc Nephrol. 2001;12(6):1211-1217.
16. Wolf G, Chen S, Han DC, Ziyadeh FN. Leptin and renal disease. Am J Kidney Dis. 2002;39(1):1-11.
17. Wu Y, Liu Z, Xiang Z, et al. Obesity-related glomerulopathy: insights from gene expression profiles of the glomeruli derived from renal biopsy samples. Endocrinology. 2006;147(1):44-50.
18. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW, Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112(12):1796-1808.
19. Flechner SM, Kolbeinsson ME, Tam J, Lum B. The impact of body weight on cyclosporine pharmacokinetics in renal transplant recipients. Transplantation. 1989;47(5):806-810.
20. Flechner SM, Haug M, Fisher RK, Modlin CS. Cyclosporine disposition and long-term renal function in a 500-pound kidney transplant recipient. Am J Kidney Dis. 1998;32(4):E4.
21. Orofino L, Pascual J, Quereda C, Burgos J, Marcen R, Ortuno J. Influence of overweight on survival of kidney transplant. Nephrol Dial Transplant. 1997;12(4):855.
22. Kasap B, Soylu A, Turkmen M, Kavukcu S, Bora S, Gulay H. Effect of obesity and overweight on cyclosporine blood levels and renal functions in renal adolescent recipients. Transplant Proc. 2006;38(2):463-465.
23. Hortal L, Fernandez A, Losada A, et al. Study of the cyclosporine concentration at 2 hours in stable renal transplant patients and relation to body mass index. Transplant Proc. 2001;33(7-8):3110-3111.
24. Yee GC, McGuire TR, Gmur DJ, Lennon TP, Deeg HJ. Blood cyclosporine pharmacokinetics in patients undergoing marrow transplantation. Influence of age, obesity, and hematocrit. Transplantation. 1988;46(3):399-402.
25. Garcia-Saiz M, Lopez-Gil A, Alfonso I, Boada JN, Armijo JA. Factors influencing cyclosporine blood concentration-dose ratio. Ann Pharmacother. 2002;36(2):193-199.
26. Modlin CS, Flechner SM, Goormastic M, et al. Should obese patients lose weight before receiving a kidney transplant? Transplantation. 1997;64(4):599-604.
27. Shibata N, Hoshino N, Minouchi T, et al. Relationship between area under the concentration versus time curve of cyclosporin A, creatinine clearance, hematocrit value, and other clinical factors in Japanese renal transplant patients. Int J Clin Pharmacol Ther. 1998;36(4):202-209.