Statistical performance evaluation and comparison of a Compton medical imaging system and a collimated Anger camera for higher energy photon imaging

Physics in Medicine and Biology

Volumn 53, Issue 24, 2008, Pages 7029-7045

  Han, Li ^a   Rogers, W Leslie ^a,b   Huh, Sam S ^a   Clinthorne, Neal ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMERAS; COMMUNICATION CHANNELS (INFORMATION THEORY); CONTROL THEORY; CRAMER-RAO BOUNDS; DIGITAL IMAGE STORAGE; DOPPLER EFFECT; IMAGING SYSTEMS; OPTOELECTRONIC DEVICES; PHOTONS; RADIOISOTOPES; SEMICONDUCTOR DEVICE MODELS; THREE DIMENSIONAL; TUMORS;

AND SCATTERINGS; ANGER CAMERAS; COMPTON CAMERAS; CYLINDRICAL PHANTOMS; DETECTION SENSITIVITIES; DISK OBJECTS; DOPPLER BROADENING; GAMMA ENERGIES; HIGH ENERGIES; HIGHER ENERGY PHOTONS; IMAGING PERFORMANCES; LIMITING FACTORS; LOWER BOUNDS; RADIATION DOSES; RADIO-NUCLIDES; SEPTAL PENETRATIONS; SPATIAL RESOLUTIONS; STATISTICAL PERFORMANCES; SYSTEM MODELING; SYSTEM PERFORMANCES; TUMOR CELLS;

MEDICAL IMAGING;

RADIOISOTOPE;

ALGORITHM; ARTICLE; COLLIMATOR; COMPARATIVE STUDY; COMPTON MEDICAL IMAGING SYSTEM; DIAGNOSTIC IMAGING; DOPPLER FLOWMETRY; ENERGY; IMAGE ANALYSIS; INTERMETHOD COMPARISON; PERFORMANCE; PHANTOM; PHOTON; PRIORITY JOURNAL; RADIATION DOSE; RADIATION MONITOR; SCINTILLATION CAMERA; SENSITIVITY AND SPECIFICITY; TUMOR CELL; VARIANCE;

ALGORITHMS; COMPUTER SIMULATION; DIAGNOSTIC IMAGING; DOPPLER EFFECT; EQUIPMENT DESIGN; FOURIER ANALYSIS; IMAGE PROCESSING, COMPUTER-ASSISTED; MODELS, STATISTICAL; NORMAL DISTRIBUTION; PHOTONS; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION;

EID: 58149250382     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/53/24/002     Document Type: Article

References (29)

1. ADAC Laboratories ARGUS System Specifications 1-6
2. Anger H O 1958 Scintillation camera Rev. Sci. Instrum. 29 27-33
3. Anger H O 1964 Scintillation camera with multichannel collimators J. Nucl. Med. 65 515-31
4. Berger J O 1985 Statistical Decision Theory and Bayesian Analysis (New York: Springer)
5. Compton A H 1923 A quantum theory of the scattering of x-rays by light elements Phys. Rev. 21 483-502
6. Davis P J 1994 Circulant Matrices (New York: Chelsea)
7. Evans R D 1982 Atomic Nucleus (New York: Krieger)
8. Fessler J A and Rogers W L 1996 Spatial resolution properties of penalized-likelihood image reconstruction: Space-invariant tomographs IEEE Trans. Med. Imaging. 5 1346-58
9. Han L 2008 Statistical performance evaluation, system modeling, distributed computation, and signal pattern matching for a Compton medical imaging system PhD Dissertation Deparment of Biomedical Engineering, The University of Michigan, Ann Arbor, MI, USA
10. Hero A O, Fessler J A and Usman M 1996 Exploring estimator bias-variance tradeoff using the uniform CR bound IEEE Trans. Signal Processing 44 2026-41
11. Hua C H, Clinthorne N H, Wilderman S J, Leblanc J W and Rogers W L 1999 Quantitative evaluation of information loss for Compton cameras IEEE Trans. Nucl. Sci. 465 587-93
12. Jan S, Santin G and Strul D 2004 GATE: a simulation toolkit for PET and SPECT Phys. Med. Bio. 49 4543-61
13. Kay S M 1993 Fundamentals of Statistical Signal Processing: Estimation Theory, Volume I (Upper Saddle River, NJ: Prentice Hall)
14. Knoll G F 2000 Radiation Detection and Measurement (New York: Wiley)
15. Kragh T J 2002 Tradeoffs and limitations in statistically based image reconstrustruction problems PhD Dissertation Department of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, MI, USA
16. Leblanc J W 1999 A Compton camera for low energy gamma ray imaging in nuclear medicine applications PhD Dissertation Department of Nuclear Engineering and Radiological Sciences, The University of Michigan, Ann Arbor, MI, USA
17. Leblanc J W, Clinthorne N H, Hua C-H, Nygard E, Rogers W L, Wehe D K, Weilhammer P and Wilderman S J 1998 C-SPRINT: A prototype Compton camera system for low energy gamma ray imaging IEEE Trans. Nucl. Sci. 45 943-9
18. Meng L J and Clinthorne N H 2004 A modified uniform Cramer-Rao bound for multiple pinhole aperture design IEEE Trans. Medical Imaging 23 896-902
19. Meng L J and Wehe D K 2003 Feasibility study of using hybrid collimation for nuclear environmental imaging IEEE Trans. Nuclear Science 55 1103-10
20. Ordonez C E, Bolozdynya A and Chang W 1997 Doppler broadening and energy uncertainties in Compton cameras IEEE Nucl. Sci. Symp. Conf. Rec. 2 1361-65
21. Parra L and Barrett H H 1998 List-mode likelihood: EM algorithm and image quality estimation demonstrated on 2D PET IEEE Trans. Medical Imaging 17 228-35
22. Philips G W 1995 Gamma-ray imaging with Compton cameras Nucl. Imaging Methods Phys. Res. B 99 674-77
23. Press W H, Teukolsky S A, Vetterling W T and Flannery B P 2002 Numerical Recipes in C: the art of scientific computing (Cambridge: Cambridge University Press)
24. Rogers W L, Clinthorne N H and Bolozdynia A 2004 Ch 19, Compton cameras for Nuclear Medical Imaging Emission Tomography: The Fundamentals of PET and SPECT ed M N Wernick and J N Aarsvold (New York: Academic) pp 383-420
25. Singh M 1983 An electronically collimated gamma camera for single-photon emission computed tomography. Part I: Theoretical considerations and design criteria. Med. Phys. 10 421-27
26. Solomon S J and Ott R J 1988 Gamma ray imaging with silicon detectors-a Compton camera for radionuclide imaging in medicine Nucl. Instrum. Methods Phys. Res. A 273 787-92
27. Todd R W, Nightingale J M and Everett D B 1974 A proposed Gamma camera Nature. 251 132-4
28. Usman M 1994 Biased and unbiased Cramer-Rao bounds: computation and application PhD Dissertation (Ann Arbor: The University of Michigan)
29. Van Trees H L 2001 Detection, Estimation, and Modulation Theory, Part I (New York: Wiley)