Development of anatomically realistic numerical breast phantoms with accurate dielectric properties for modeling microwave interactions with the human breast

IEEE Transactions on Biomedical Engineering

Volumn 55, Issue 12, 2008, Pages 2792-2800

  Zastrow, Earl ^a   Davis, Shakti K ^a   Lazebnik, Mariya ^b   Kelcz, Frederick ^c   Veen, Barry D Van ^a   Hagness, Susan C ^a  

^a University of Wisconsin Madison   (United States)

^b MEDTRONIC INC   (United States)

^c University of Wisconsin Health   (United States)

Author keywords

Biomedical applications of electromagnetic radiation; Biomedical electromagnetic imaging; Breast cancer detection; Breast cancer treatment; Finite difference time domain (FDTD) methods; Microwave hyperthermia; Microwave imaging

Indexed keywords

BIOMEDICAL APPLICATIONS OF ELECTROMAGNETIC RADIATION; BIOMEDICAL ELECTROMAGNETIC IMAGING; BREAST CANCER DETECTION; BREAST CANCER TREATMENT; FINITE-DIFFERENCE TIME-DOMAIN (FDTD) METHODS; MICROWAVE HYPERTHERMIA; MICROWAVE IMAGING;

ANIMAL CELL CULTURE; CERAMIC CAPACITORS; DATA STORAGE EQUIPMENT; DIELECTRIC PROPERTIES; ELECTROMAGNETIC WAVE EMISSION; ELECTROMAGNETIC WAVES; ELECTROMAGNETISM; ELECTRON OPTICS; FINITE DIFFERENCE TIME DOMAIN METHOD; FLOW INTERACTIONS; IMAGE PROCESSING; IMAGING SYSTEMS; MAGNETIC MATERIALS; MATHEMATICAL MODELS; METHOD OF MOMENTS; MICROWAVES; PIECEWISE LINEAR TECHNIQUES; THREE DIMENSIONAL;

TIME DOMAIN ANALYSIS;

BREAST; ELECTROMAGNETIC PHENOMENA; FEMALE; FINITE ELEMENT ANALYSIS; HUMANS; IMAGING, THREE-DIMENSIONAL; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MAMMOGRAPHY; MICROWAVES; MODELS, STRUCTURAL; PHANTOMS, IMAGING; WEIGHTS AND MEASURES;

EID: 58149248075     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2008.2002130     Document Type: Article

References (42)

1. B. Bocquet, J. C. van de Velde, A. Mamouni, Y. Leroy, R. Giaux, J. Delannoy, and D. Delvalee, "Microwave radiometric imaging at 3-GHz for the exploration of breast tumors," IEEE Trans. Microw. Theory Tech., vol. 38, no. 6, pp. 791-793, Jun. 1990.
2. S. C. Hagness, A. Taflove, and J. E. Bridges, "Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors," IEEE Trans. Biomed. Eng., vol. 45, no. 12, pp. 1470-1478, Dec. 1998.
3. R. A. Kruger, K. K. Kopecky, A. M. Aisen, D. R. Reinecke, G. A. Kruger, and W. L. Kiser, Jr., "Thermoacoustic CT with radio waves: A medical imaging paradigm," Radiology, vol. 211, pp. 275-278, 1999.
4. P. M. Meaney, K. D. Paulsen, J. T. Chang, M. W. Fanning, and A. Hartov, "Nonactive antenna compensation for fixed-array microwave imaging: Part II - Imaging results," IEEE Trans. Med. Imag., vol. 18, no. 6, pp. 508-518, Jun 1999.
5. E. C. Fear, "Microwave imaging of the breast," Technol. Cancer Res. Treat., vol. 4, no. 1, pp. 69-82, 2005.
6. P. Meaney, M. W. Fanning, T. Raynolds, C. J. Fox, Q. Fang, C. A. Kogel, S. P. Poplack, and K. D. Paulsen, "Initial clinical experience with microwave breast imaging in women with normal mammography," Acad. Radiol., vol. 14, no. 2, pp. 207-218, 2007.
7. D. W. Winters, E. J. Bond, B. D. Van Veen, and S. C. Hagness, "Estimation of the frequency-dependent average dielectric properties of breast tissue using a time-domain inverse scattering technique," IEEE Trans. Antennas Propag., vol. 54, no. 11, pp. 3517-3528, Nov. 2006.
8. A. Fhager, P. Hashemzadeh, and M. Persson, "Reconstruction quality and spectral content of an electromagnetic time-domain inversion algorithm," IEEE Trans. Biomed. Eng., vol. 53, no. 8, pp. 1594-1604, Aug. 2006.
9. H. B. Jiang, C. Q. Li, D. Pearlstone, and L. L. Fajardo, "Ultrasound-guided microwave imaging of breast cancer: Tissue phantom and pilot clinical experiments," Med. Phys., vol. 32, no. 8, pp. 2528-2535, 2005.
10. Z. Q. Zhang and Q. H. Liu, "Three-dimensional nonlinear image reconstruction for microwave biomedical imaging," IEEE Trans. Biomed. Eng., vol. 51, no. 3, pp. 544-548, Mar. 2004.
11. X. Li, E. J. Bond, B. D. V. Veen, and S. C. Hagness, "An overview of ultrawideband microwave imaging via space-time beamforming for early-stage breast-cancer detection," IEEE Antennas Propag. Mag., vol. 47, no. 1, pp. 19-34, Feb. 2005.
12. J. M. Sill and E. C. Fear, "Tissue sensing adaptive radar for breast cancer detection - Experimental investigation of simple tumor models," IEEE Trans. Microw. Theory Tech., vol. 53, no. 11, pp. 3312-3319, Nov. 2005.
13. S. K. Davis, H. Tandradinata, S. C. Hagness, and B. D. Van Veen, "Ultrawideband microwave breast cancer detection: A detection theoretic approach using the generalized likelihood ratio test," IEEE Trans. Biomed. Eng., vol. 52, no. 7, pp. 1237-1250, Jul. 2005.
14. P. Kosmas and C. M. Rappaport, "FDTD-based time reversal for microwave breast cancer detection - Localization in three dimensions," IEEE Trans. Microw. Theory Tech., vol. 54, no. 4, pp. 1921-1927, Jun 2006.
15. Y. Chen, E. Gunawan, K. S. Low, S. Wang, Y. Kim, and C. Soh, "Pulse design for time reversal method as applied to ultrawideband microwave breast cancer detection: A two-dimensional analysis," IEEE Trans. Antennas Propag., vol. 55, no. 1, pp. 194-204, Jan 2007.
16. G. Ku, B. D. Fornage, X. Jin, M. H. Xu, K. K. Hunt, and L. V. Wang, "Thermoacoustic and photoacoustic tomography of thick biological tissues toward breast imaging," Technol. Cancer Res. Treat., vol. 4, no. 5, pp. 559-565, 2005.
17. R. A. Kruger, K. D. Miller, H. E. Reynolds, J. W. L. Kiser, D. R. Reinecke, and G. A. Kruger, "Breast cancer in vivo: Contrast enhancement with thermoacoustic CT at 434 MHz - Feasibility study," Radiology, vol. 216, pp. 279-283, 2000.
18. S. Mouty, B. Bocquet, R. Ringot, N. Rocourt, and P. Devos, "Microwave radiometric imaging for the characterisation of breast tumors," Eur. Phys. J.: Appl. Phys., vol. 10, pp. 73-78, 2000.
19. M. El Shenawee, "Numerical assessment of multifrequency microwave radiometry for sensing malignant breast cancer tumors," Microw. Opt. Technol. Lett., vol. 36, no. 5, pp. 394-398, 2003.
20. F. Bardati and S. Iudicello, "Modeling the visibility of breast malignancy by a microwave radiometer," IEEE Trans. Biomed. Eng., vol. 55, no. 1, pp. 214-221, Jan 2008.
21. M. Elsdon, D. Smith, M. Leach, and S. J. Foti, "Experimental investigation of breast tumor imaging using indirect microwave holography," Microw. Opt. Technol. Lett., vol. 48, no. 3, pp. 480-482, 2006.
22. A. J. Fenn, G. L. Wolf, and R. M. Fogle, "An adaptive microwave phased array for targeted heating of deep tumours in intact breast: Animal study results," Int. J. Hyperthermia, vol. 15, no. 1, pp. 45-61, 1999.
23. R. A. Gardner, H. I. Vargas, J. B. Block, C. L. Vogel, A. J. Fenn, G. V. Kuehl, and M. Doval, "Focused microwave phased array thermotherapy for primary breast cancer," Ann. Surg. Oncol., vol. 9, no. 4, pp. 326-332, 2002.
24. H. I. Vargas, W. C. Dooley, R. A. Gardner, K. D. Gonzalez, R. Venegas, S. H. Heywang-Kobrunner, and A. J. Fenn, "Focused microwave phased array thermotherapy for ablation of early-stage breast cancer: Results of thermal dose escalation," Ann. Surg. Oncol., vol. 11, no. 2, pp. 139-146, 2004.
25. M. Converse, E. J. Bond, S. C. Hagness, and B. D. Van Veen, "Ultrawideband microwave space-time beamforming for hyperthermia treatment of breast cancer: A computational feasibility study," IEEE Trans. Microw. Theory Tech., vol. 52, no. 8, pp. 1876-1889, Aug. 2004.
26. B. Guo, L. Xu, and J. Li, "Time reversal based microwave hyperthermia treatment of breast cancer," Microw. Opt. Technol. Lett., vol. 47, no. 4, pp. 335-338, 2005.
27. M. Converse, E. J. Bond, B. D. Van Veen, and S. C. Hagness, "A computational study of ultrawideband versus narrowband microwave hyperthermia for breast cancer treatment," IEEE Trans. Microw. Theory Tech., vol. 54, no. 5, pp. 2169-2180, May 2006.
28. S. Jacobsen and P. R. Stauffer, "Can we settle with single-band radiometric temperature monitoring during hyperthermia treatment of chestwall recurrence of breast cancer using a dual-mode transceiving applicator?" Phys. Med. Biol., vol. 52, no. 4, pp. 911-928, 2007.
29. A. Taflove and S. C. Hagness, Computational Electrodynamics: The Finite-Difference Time-Domain Method, 3rd ed. Norwood, MA: Artech House, 2005.
30. E. C. Fear and M. Okoniewski, "Confocal microwave imaging for breast tumor detection: Application to a hemispherical breast model," in Proc. 2002 IEEE MTT-S Int. Microw. Symp. Dig., vol. 3, pp. 1759-1762.
31. E. Zastrow, S. K. Davis, and S. C. Hagness, "Safety assessment of breast cancer detection via ultrawideband microwave radar operating in pulsed-radiation mode," Microw. Opt. Technol. Lett., vol. 49, no. 1, pp. 221-225, 2007.
32. M. Lazebnik, L. McCartney, D. Popovic, C. B. Watkins, M. J. Lindstrom, J. Harter, S. Sewall, A. Magliocco, J. H. Booske, M. Okoniewski, and S. C. Hagness, "A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries," Phys. Med. Biol., vol. 52, pp. 2637-2656, 2007.
33. M. Lazebnik, D. Popovic, L. McCartney, C. B. Watkins, M. J. Lindstrom, J. Harter, S. Sewall, T. Ogilvie, A. Magliocco, T. M. Breslin, W. Temple, D. Mew, J. H. Booske, M. Okoniewski, and S. C. Hagness, "A large-scale study of the ultrawideband microwave dielectric properties of normal, benign andmalignant breast tissues obtained from cancer surgeries," Phys. Med. Biol., vol. 52, pp. 6093-6115, 2007.
34. R. A. Redner and H. F. Walker, "Mixture densities, maximum likelihood and the EM algorithm," SIAM Rev., vol. 26, no. 2, pp. 195-239, 1984.
35. American College of Radiology, Breast Imaging Reporting and Data System (BI-RADS) Atlas, 4th ed. Reston, VA: Amer. Coll. Radiol., 2003.
36. R. C. Gonzalez and R. E. Woods, Digital Image Processing, 2nd ed. Upper Saddle River, NJ: Prentice-Hall, 2002.
37. R. M. Haralick and L. G. Shapiro, Computer and Robot Vision, 1st ed. Boston, MA: Addison-Wesley, 1992.
38. J. T. L. Pope, M. E. Read, T. Medsker, A. J. Buschi, and A. N. Brenbridge, "Breast skin thickness: Normal range and causes of thickening shown on film-screen mammography," J. Can. Assoc. Radiol., vol. 35, pp. 365-368, 1984.
39. S. K. Davis, "Ultrawideband radar-based detection and classification of breast tumors," Ph.D. dissertation, Univ. Wisconsin, Madison, 2006.
40. M. Lazebnik, M. Okoniewski, J. H. Booske, and S. C. Hagness, "Highly accurate Debye models for normal and malignant breast tissue dielectric properties at microwave frequencies," IEEE Microw. Wireless Compon. Lett., vol. 17, no. 12, pp. 822-824, Dec 2007.
41. S. Gabriel, R. W. Lau, and C. Gabriel, "The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues," Phys. Med. Biol., vol. 41, pp. 2271-2293, 1996.
42. S. K. Davis, B. D. Van Veen, S. C. Hagness, and F. Kelcz, "Breast tumor characterization based on ultrawideband microwave backscatter," IEEE Trans. Biomed. Eng., vol. 55, no. 1, pp. 237-246, Jan 2008.