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Volumn 18, Issue 1, 2009, Pages 79-84

Angiotensin-converting enzyme 2: Implications for blood pressure and kidney disease

Author keywords

Angiotensin 1 7; Angiotensin 1 9; Angiotensin II; Angiotensin converting enzyme; Angiotensin converting enzyme 2; Renin angiotensin system

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; COMPLEMENTARY DNA; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FLUORESCEIN; LENTIVIRUS VECTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OLMESARTAN; STREPTOZOCIN; XANTHONE 4 ACETIC ACID;

EID: 58149247936     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNH.0b013e32831b70ad     Document Type: Review
Times cited : (58)

References (44)
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    • • Mizuiri S, Hemmi H, Arita M, et al. Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls. Am J Kidney Dis 2008; 51:613-623. This study compares ACE and ACE2 expression in kidneys of normal subjects and in those with diabetes. They conclude that the high ACE/ACE2 ratio in the kidneys of patients with type 2 diabetes may contribute to renal injury.
    • • Mizuiri S, Hemmi H, Arita M, et al. Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls. Am J Kidney Dis 2008; 51:613-623. This study compares ACE and ACE2 expression in kidneys of normal subjects and in those with diabetes. They conclude that the high ACE/ACE2 ratio in the kidneys of patients with type 2 diabetes may contribute to renal injury.
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    • • Wang G, Lai FM-M, Lai K-B, et al. Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy. Diabetologia 2008; 51:1062-1067. This study showed that urinary expression of ACE2 mRNA correlated with proteinuria.
    • • Wang G, Lai FM-M, Lai K-B, et al. Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy. Diabetologia 2008; 51:1062-1067. This study showed that urinary expression of ACE2 mRNA correlated with proteinuria.
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    • •• Hernandez Prada JA, Ferreira AJ, Katovich MJ, et al. Structure-based identi-fication of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension 2008; 51:1312-1317. This study suggests that ACE2 activators may be useful as a strategy to treat hypertension.
    • •• Hernandez Prada JA, Ferreira AJ, Katovich MJ, et al. Structure-based identi-fication of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension 2008; 51:1312-1317. This study suggests that ACE2 activators may be useful as a strategy to treat hypertension.
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    • 1' subsite. Bioorganic Med Chem Lett 2008; 18:1681-1687. This study explores potential ACE2 inhibitors.
    • 1' subsite. Bioorganic Med Chem Lett 2008; 18:1681-1687. This study explores potential ACE2 inhibitors.
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    • • Lew RA, Warner FJ, Hanchapola I, et al. Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor. Exp Physiol 2008; 93:685-693. This study demonstrates that an endogenous inhibitor may mask ACE2 activity in human plasma.
    • • Lew RA, Warner FJ, Hanchapola I, et al. Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor. Exp Physiol 2008; 93:685-693. This study demonstrates that an endogenous inhibitor may mask ACE2 activity in human plasma.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.