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Volumn 71, Issue 18, 2008, Pages 1386-1387

Statins to treat multiple sclerosis: Friend or foe?

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; BETA1A INTERFERON; GADOLINIUM; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PLACEBO;

EID: 58149238092     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000327876.72639.e7     Document Type: Editorial
Times cited : (12)

References (12)
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    • The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
    • Youssef S, Stuve O, Patarroyo JC, et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature 2002;420:78-84.
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  • 2
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    • Statins as immunomodulators: Comparison with interferon-β1b in MS
    • Neuhaus O, Strasser-Fuchs S, Fazekas F, et al. Statins as immunomodulators: comparison with interferon-β1b in MS. Neurology 2002;59:990-997.
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    • Neuhaus, O.1    Strasser-Fuchs, S.2    Fazekas, F.3
  • 3
    • 44849127754 scopus 로고    scopus 로고
    • Oral high-dose atar-vastatin treatment in relapsing-remitting multiple sclerosis
    • Paul F, Waiczies S, Wuerfel J, et al. Oral high-dose atar-vastatin treatment in relapsing-remitting multiple sclerosis. PLoS ONE 2008;3:e1928.
    • (2008) PLoS ONE , vol.3
    • Paul, F.1    Waiczies, S.2    Wuerfel, J.3
  • 4
    • 2442561768 scopus 로고    scopus 로고
    • Oral simvastatin treatment in relapsing-remitting multiple sclerosis
    • Vollmer T, Key L, Durkalski V, et al. Oral simvastatin treatment in relapsing-remitting multiple sclerosis. Lancet 2004;363:1607-1608.
    • (2004) Lancet , vol.363 , pp. 1607-1608
    • Vollmer, T.1    Key, L.2    Durkalski, V.3
  • 5
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    • Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis
    • Birnbaum G, Cree B, Altafullah I, Zinser M, Reder AT. Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis. Neurology 2008;71: 1390-1395.
    • (2008) Neurology , vol.71 , pp. 1390-1395
    • Birnbaum, G.1    Cree, B.2    Altafullah, I.3    Zinser, M.4    Reder, A.T.5
  • 6
    • 66949137231 scopus 로고    scopus 로고
    • Statin and intramuscular interferon beta-1a combination therapy is safe and well tolerated in patients with clinically isolated syndrome suggestive of multiple sclerosis, a pilot study
    • Abstract
    • Markovic-Plese S, Speer D, Jin J, Smrtka J, Ingram L, Jewells V. Statin and intramuscular interferon beta-1a combination therapy is safe and well tolerated in patients with clinically isolated syndrome suggestive of multiple sclerosis, a pilot study. Mult Scler 2007;13: S270. Abstract.
    • (2007) Mult Scler , vol.13
    • Markovic-Plese, S.1    Speer, D.2    Jin, J.3    Smrtka, J.4    Ingram, L.5    Jewells, V.6
  • 7
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    • An open label randomised clinical trial of atorvastatin in combination with IFN beta-1a in active MS patients: 12 months results
    • Abstract
    • Orefice G, Quarantelli M, Salvatore P, et al. An open label randomised clinical trial of atorvastatin in combination with IFN beta-1a in active MS patients: 12 months results. Mult Scler 2007;13:S56-S57. Abstract.
    • (2007) Mult Scler , vol.13
    • Orefice, G.1    Quarantelli, M.2    Salvatore, P.3
  • 8
    • 66949125162 scopus 로고    scopus 로고
    • Effects of statins on intramuscular interferon beta-1a for relapsing-remitting multiple sclerosis
    • Abstract
    • Rudick R, Pace A, Panzara M, et al. Effects of statins on intramuscular interferon beta-1a for relapsing-remitting multiple sclerosis. Mult Scler 2007;13:S57. Abstract.
    • (2007) Mult Scler , vol.13
    • Rudick, R.1    Pace, A.2    Panzara, M.3
  • 9
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    • Does simvastatin antagonise the effect of interferon beta? Interim safety analysis of the ongoing SIMCOMBIN study
    • Abstract
    • Sorensen PS, Frederiksen JL, Lycke J, Sellebjerg F. Does simvastatin antagonise the effect of interferon beta? Interim safety analysis of the ongoing SIMCOMBIN study. Mult Scler 2007;13:S25. Abstract.
    • (2007) Mult Scler , vol.13
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  • 10
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    • Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases
    • Kieseier BC, Archelos JJ, Hartung HP. Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases. Arch Neurol 2004;61:929-932.
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    • Kieseier, B.C.1    Archelos, J.J.2    Hartung, H.P.3
  • 11
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    • Ioannidis JPA. Why most published research findings are false. PloS Medicine 2005;2:e124.
  • 12
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    • Marrie RA. PhD Thesis: The influence of comorbid diseases and health behaviors on clinical characteristics, disability at diagnosis, and disability progression in multiple sclerosis. Epidemiology and Biostatistics, Case Western Reserve University, 2007.
    • Marrie RA. PhD Thesis: The influence of comorbid diseases and health behaviors on clinical characteristics, disability at diagnosis, and disability progression in multiple sclerosis. Epidemiology and Biostatistics, Case Western Reserve University, 2007.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.