Medical management of patients with ileal pouch anal anastomosis after restorative procto-colectomy

European Journal of Gastroenterology and Hepatology

Volumn 21, Issue 1, 2009, Pages 9-17

  Johnson, Matthew W ^a   Das, Partha ^a   Dewar, David H ^b   Forbes, Alastair ^c   Ciclitira, Paul J ^b   Nicholls, Richard J ^d  

^a ST MARK S HOSPITAL   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Ileal pouch anal anastomosis; Medical management; Pouchitis; Restorative procto colectomy; Surveillance; Treatment

Indexed keywords

ALLOPURINOL; AMOXICILLIN PLUS CLAVULANIC ACID; AZATHIOPRINE; BISPHOSPHONIC ACID DERIVATIVE; BUDESONIDE; CIPROFLOXACIN; CODEINE; COLESTYRAMINE; CORTICOSTEROID; CYCLOSPORIN; ERYTHROMYCIN; INFLIXIMAB; ISPAGULA; LIDOCAINE; LOPERAMIDE; MESALAZINE; METHYLCELLULOSE; METRONIDAZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; PROBIOTIC AGENT; RIFAMPICIN; SHORT CHAIN FATTY ACID; STEROID; TACROLIMUS; TETRACYCLINE;

CLINICAL TRIAL; CROHN DISEASE; DIFFERENTIAL DIAGNOSIS; DISEASE ACTIVITY; DISEASE CONTROL; DRUG DOSE COMPARISON; DYSPLASIA; HUMAN; ILEITIS; ILEOANAL ANASTOMOSIS; ILEUM DISEASE; MALABSORPTION; NONHUMAN; OSTEOPENIA; OSTEOPOROSIS; PATIENT CARE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROCTOCOLECTOMY; RECURRENT DISEASE; REVIEW; SEXUAL DYSFUNCTION; SIGMOIDOSCOPY; UNSPECIFIED SIDE EFFECT;

EID: 58149229449     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328306078c     Document Type: Review

References (129)

1. Katz JA. Prevention is the best defense: probiotic prophylaxis of pouchitis. Gastroenterology 2003; 124:1535-1538.
2. Langholz E, Munkholm P, Davidsen M, Binder V. Long-term prognosis of patients with ulcerative colitis. Ugeskr Laeger 1993; 155:3767-3772.
3. Panis Y, Poupard B, Nemeth J, Lavergne A, Hautefeuille P, Valleur P. Ileal pouch/anal anastomosis for Crohn's disease. Lancet 1996; 347:854-857.
4. Grobler SP, Hosie KB, Affie E, Thompson H, Keighley MR. Outcome of restorative proctocolectomy when the diagnosis is suggestive of Crohn's disease. Gut 1993; 34:1384-1388.
5. Fazio VW, Ziv Y, Church JM, Oakley JR, Lavery IC, Milsom JW, et al. Ileal pouch-anal anastomoses complications and function in 1005 patients. Ann Surg 1995; 222:120-127.
6. Parks AG, Nicholls RJ. Proctocolectomy without ileostomy for ulcerative colitis. Br Med J 1978; 2:85-88.
7. O'Connell PR, Pemberton JH, Weiland LH, Beart RW Jr, Dozois RR, Wolff BG, et al. Does rectal mucosa regenerate after ileoanal anastomosis? Dis Colon Rectum 1987; 30:1-5.
8. McIntyre PB, Pemberton JH, Beart RW Jr, Devine RM, Nivatvongs S. Double-stapled vs. handsewn ileal pouch-anal anastomosis in patients with chronic ulcerative colitis. Dis Colon Rectum 1994; 37:430-433.
9. Luukkonen P, Jarvinen H. Stapled vs hand-sutured ileoanal anastomosis in restorative proctocolectomy. A prospective, randomized study. Arch Surg 1993; 128:437-440.
10. Ho YH, Tan M, Leong AF, Seow-Choen F. Ambulatory manometry in patients with colonic J-pouch and straight coloanal anastomoses: randomized, controlled trial. Dis Colon Rectum 2000; 43:793-799.
11. Lewis WG, Miller AS, Williamson ME, Sagar PM, Holdsworth PJ, Axon AT, et al. The perfect pelvic pouch-what makes the difference? Gut 1995; 37:552-556.
12. Tuckson WB, McNamara MJ, Fazio VW, Lavery IC, Oakley JR. Impact of anal manipulation and pouch design on ileal pouch function. J Natl Med Assoc 1991; 83:1089-1092.
13. Wexner SD, James K, Jagelman DG. The double-stapled ileal reservoir and ileoanal anastomosis. A prospective review of sphincter function and clinical outcome. Dis Colon Rectum 1991; 34:487-494.
14. Herbst F, Kamm MA, Nicholls RJ. Effects of loperamide on ileoanal pouch function. Br J Surg 1998; 85:1428-1432.
15. Emblem R, Stien R, Morkrid L. The effect of loperamide on bowel habits and anal sphincter function in patients with ileoanal anastomosis. Scand J Gastroenterol 1989; 24:1019-1024.
16. Hallgren T, Fasth S, Delbro DS, Nordgren S, Oresland T, Hulten L. Loperamide improves anal sphincter function and continence after restorative proctocolectomy. Dig Dis Sci 1994; 39:2612-2618.
17. Thompson-Fawcett MW, Jewell DP, Mortensen NJ. Ileoanal reservoir dysfunction: a problem-solving approach. Br J Surg 1997; 84:1351-1359.
18. De Silva HJ, de Angelis CP, Soper N, Kettlewell MG, Mortensen NJ, Jewell DP. Clinical and functional outcome after restorative proctocolectomy. Br J Surg 1991; 78:1039-1044.
19. Oresland T, Fasth S, Nordgren S, Akervall S, Hulten L. Pouch size: the important functional determinant after restorative proctocolectomy. Br J Surg 1990; 77:265-269.
20. Johnston D, Williamson ME, Lewis WG, Miller AS, Sagar PM, Holdsworth PJ. Prospective controlled trial of duplicated (J) versus quadruplicated (W) pelvic ileal reservoirs in restorative proctocolectomy for ulcerative colitis. Gut 1996; 39:242-247.
21. Pezim ME, Nicholls RJ. Quality of life after restorative proctocolectomy with pelvic ileal reservoir. Br J Surg 1985; 72:31-33.
22. Becker JM, McGrath KM, Meagher MP, Parodi JE, Dunnegan DA, Soper NJ. Late functional adaptation after colectomy, mucosal proctectomy, and ileal pouch-anal anastomosis. Surgery 1991; 110:718-724.
23. Harms BA, Andersen AB, Starling JR. The W ileal reservoir: long-term assessment after proctocolectomy for ulcerative colitis and familial polyposis. Surgery 1992; 112:638-646.
24. Pastrana RJ, Torres EA, Arroyo JM, Rivera CE, Sanchez CJ, Morales L. Iron-deficiency anemia as presentation of pouchitis. J Clin Gastroenterol 2007; 41:41-44.
25. Johnson MW, Dewar DH, Forbes A, Ciclitira PJ, Nicholls PJ. Nutritional deficiency in ileal pouch patients: is it related to histology? Gut 2005; 54 (Suppl 7):A235.
26. Kuisma J, Nuutinen H, Luukkonen P, Jarvinen H, Kahri A, Farkkila M. Long term metabolic consequences of ileal pouch-anal anastomosis for ulcerative colitis. Am J Gastroenterol 2001; 96:3110-3116.
27. M'koma AE. Serum biochemical evaluation of patients with functional pouches 10 to 20 years after restorative proctocolectomy. Int J Colorectal Dis 2006; 21:711-720.
28. Abitbol V, Roux C, Guillemant S, Valleur P, Hautefeuille P, Dougados M, et al. Bone assessment in patients with ileal pouch-anal anastomosis for inflammatory bowel disease. Br J Surg 1997; 84:1551-1554.
29. Carpenter GH, Proctor GB, Pankhurst CL, O'Donohue J, Scott D, Hunnable MP. Sialochemical markers of salivary gland involvement with Sjogren's syndrome secondary to rheumatoid arthritis and primary biliary cirrhosis. J Oral Pathol Med 2000; 29:452-459.
30. Mahadevan U. Fertility and pregnancy in the patient with inflammatory bowel disease. Gut 2006; 55:1198-1206.
31. Gorgun E, Remzi FH, Montague DK, Connor JT, O'Brien K, Loparo B, et al. Male sexual function improves after ileal pouch anal anastomosis. Colorectal Dis 2005; 7:545-550.
32. Willoughby CP, Truelove SC. Ulcerative colitis and pregnancy. Gut 1980; 21:469-474.
33. Oresland T, Palmblad S, Ellstrom M, Berndtsson I, Crona N, Hulten L. Gynaecological and sexual function related to anatomical changes in the female pelvis after restorative proctocolectomy. Int J Colorectal Dis 1994; 9:77-81.
34. Ording OK, Juul S, Berndtsson I, Oresland T, Laurberg S. Ulcerative colitis: female fecundity before diagnosis, during disease, and after surgery compared with a population sample. Gastroenterology 2002; 122:15-19.
35. Waljee A, Waljee J, Morris A, Higgins PD. Three-fold increased risk of infertility: a meta-analysis of infertility after pouch surgery in ulcerative colitis. Gut 2006; 55:1575-1580.
36. Olsen KO, Juul S, Bulow S, Jarvinen HJ, Bakka A, Bjork J et al. Female fecundity before and after operation for familial adenomatous polyposis. Br J Surg 2003; 90:227-231.
37. Olsen KO, Joelsson M, Laurberg S, Oresland T. Fertility after ileal pouch-anal anastomosis in women with ulcerative colitis. Br J Surg 1999; 86:493-495.
38. Wolf JL. The impact of surgery for ulcerative colitis on fertility and sexual function in women. Gastroenterology 2002; 122:226-227.
39. Schmidt CM, Lazenby AJ, Hendrickson PJ, Sitzmann JV. Preoperative terminal ileal and colonic resection histopathology predicts risk of pouchitis in patients after ileoanal pull-through procedure. Ann Surg 1998; 227:654-662.
40. Penna C, Dozois R, Tremaine W, Sandborn W, LaRusso N, Schleck C, et al. Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis. Gut 1996; 38:234-239.
41. Lohmuller JL, Pemberton JH, Dozois RR, Ilstrup D, van HJ. Pouchitis and extraintestinal manifestations of inflammatory bowel disease after ileal pouch-anal anastomosis. Ann Surg 1990; 211:622-627.
42. Hata K, Watanabe T, Shinozaki M, Nagawa H. Patients with extraintestinal manifestations have a higher risk of developing pouchitis in ulcerative colitis: multivariate analysis. Scand J Gastroenterol 2003; 38:1055-1058.
43. Fleshner PR, Vasiliauskas EA, Kam LY, Fleshner NE, Gaiennie J, breu-Martin MT, et al. High level perinuclear antineutrophil cytoplasmic antibody (pANCA) in ulcerative colitis patients before colectomy predicts the development of chronic pouchitis after ileal pouch-anal anastomosis. Gut 2001; 49:671-677.
44. Kuisma J, Jarvinen H, Kahri A, Farkkila M. Factors associated with disease activity of pouchitis after surgery for ulcerative colitis. Scand J Gastroenterol 2004; 39:544-548.
45. Shen B, Fazio VW, Remzi FH, Brzezinski A, Bennett AE, Lopez R, et al. Risk factors for diseases of ileal pouch-anal anastomosis after restorative proctocolectomy for ulcerative colitis. Clin Gastroenterol Hepatol 2006; 4:81-89.
46. Moskowitz RL, Shepherd NA, Nicholls RJ. An assessment of inflammation in the reservoir after restorative proctocolectomy with ileoanal ileal reservoir. Int J Colorectal Dis 1986; 1:167-174.
47. Setti Carraro PG, Talbot IC, Nicholls JR. Patterns of distribution of endoscopic and histological changes in the ileal reservoir after restorative proctocolectomy for ulcerative colitis. A long-term follow-up study. Int J Colorectal Dis 1998; 13:103-107.
48. Veress B, Reinholt FP, Lindquist K, Liljeqvist L. Different types of mucosal adaptation in the ileal reservoir after restorative proctocolectomy. A 2-year follow-up study. APMIS 1990; 98:786-796.
49. Mahadevan U, Sandborn WJ. Diagnosis and management of pouchitis. Gastroenterology 2003; 124:1636-1650.
50. Pardi DS, Sandborn WJ. Systematic review: the management of pouchitis. Aliment Pharmacol Ther 2006; 23:1087-1096.
51. Meagher AP, Farouk R, Dozois RR, Kelly KA, Pemberton JH. J ileal pouch-anal anastomosis for chronic ulcerative colitis: complications and long-term outcome in 1310 patients. Br J Surg 1998; 85:800-803.
52. Stahlberg D, Gullberg K, Liljeqvist L, Hellers G, Lofberg R. Pouchitis following pelvic pouch operation for ulcerative colitis. Incidence, cumulative risk and risk factors. Dis Colon Rectum 1996; 39:1012-1018.
53. Veress B, Reinholt FP, Lindquist K, Liljeqvist L. Prospective studies of the mucosa of the ileoanal pouch. Gastroenterology 1995; 108:953-954.
54. Tulchinsky H, Hawley PR, Nicholls J. Long-term failure after restorative proctocolectomy for ulcerative colitis. Ann Surg 2003; 238:229-234.
55. Oresland T, Fasth S, Nordgren S, Hallgren T, Hulten L. A prospective randomized comparison of two different pelvic pouch designs. Scand J Gastroenterol 1990; 25:986-996.
56. Sagar PM, Holdsworth PJ, Godwin PG, Quirke P, Smith AN, Johnston D. Comparison of triplicated (S) and quadruplicated (W) pelvic ileal reservoirs. Studies on manovolumetry, fecal bacteriology, fecal volatile fatty acids, mucosal morphology, and functional results. Gastroenterology 1992; 102:520-528.
57. Shepherd NA, Healey CJ, Warren BF, Richman PI, Thomson WH, Wilkinson SP. Distribution of mucosal pathology and an assessment of colonic phenotypic change in the pelvic ileal reservoir. Gut 1993; 34:101-105.
58. Sandborn WJ, Pardi DS. Clinical management of pouchitis. Gastroenterology 2004; 127:1809-1814.
59. Tsunoda A, Talbot IC, Nicholls RJ. Incidence of dysplasia in the anorectal mucosa in patients having restorative proctocolectomy. Br J Surg 1990; 77:506-508.
60. Sandbom WJ, Tremaine WJ, Batts KP, Pemberton JH, Phillips SF. Pouchitis after ileal pouch-anal anastomosis: a pouchitis disease activity index. Mayo Clin Proc 1994; 69:409-415.
61. Johnson MW, Maestranzi S, Dewar DH, Forbes A, Bjarnason I, Sherwood R, et al. Validation of the new 'PhiCal' faecal Calprotectin test as a diagnostic tool for pouchitis. Gut 2006; 56 (Suppl II):A112.
62. Shepherd NA, Jass JR, Duval I, Moskowitz RL, Nicholls RJ, Morson BC. Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens. J Clin Pathol 1987; 40:601-607.
63. Ton H, Brandsnes O, Dale S, Holtlund J, Skuibina E, Schjonsby H, et al. Improved assay for fecal calprotectin. Clin Chim Acta 2000; 292:41-54.
64. Parsi MA, Shen B, Achkar JP, Remzi FF, Goldblum JR, Boone J, et al. Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis. Gastroenterology 2004; 126:1280-1286.
65. Johnson MW, Maestranzi S, Dewar DH, Forbes A, Ciclitira PJ, Nicholls PJ. Faecal M2-pyruvate kinase; a novel noninvasive marker of ileal pouch inflammation. Gut 2006; 55 (Suppl 5):A116-A117.
66. Madden MV, McIntyre AS, Nicholls RJ. Double-blind crossover trial of metronidazole versus placebo in chronic unremitting pouchitis. Dig Dis Sci 1994; 39:1193-1196.
67. Hurst RD, Molinari M, Chung TP, Rubin M, Michelassi F. Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy. Arch Surg 1996; 131:497-500.
68. Shen B, Achkar JP, Lashner BA, Ormsby AH, Remzi FH, Brzezinski A, et al. A randomized clinical trial of ciprofloxacin and metronidazole to treat acute pouchitis. Inflamm Bowel Dis 2001; 7:301-305.
69. Scott AD, Phillips RK. Ileitis and pouchitis after colectomy for ulcerative colitis. Br J Surg 1989; 76:668-669.
70. Shen B, Achkar JP, Lashner BA, Ormsby AH, Remzi FH, Bevins CL et al. Endoscopic and histologic evaluation together with symptom assessment are required to diagnose pouchitis. Gastroenterology 2001; 121:261-267.
71. Gionchetti P, Rizzello F, Venturi A, Ugolini F, Rossi M, Brigidi P, et al. Antibiotic combination therapy in patients with chronic, treatment-resistant pouchitis. Aliment Pharmacol Ther 1999; 13:713-718.
72. Abdelrazeq AS, Lund JN, Leveson SH. Pouchitis-associated pyoderma gangrenosum following restorative proctocolectomy for ulcerative colitis. Eur J Gastroenterol Hepatol 2004; 16:1057-1058.
73. Mimura T, Rizzello F, Herwig U, Poggioli G, Schreiber S, Talbot IC, et al. Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis. Aliment Pharmacol Ther 2002; 16:909-917.
74. Schaafsma G. State of the art concerning probiotic strains in milk products. IDF Nutri Newslett 1996; 5:23-24.
75. Gionchetti P, Rizzello F, Venturi A, Brigidi P, Matteuzzi D, Bazzocchi G, et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 2000; 119:305-309.
76. Gionchetti P, Rizzello F, Helwig U, Venturi A, Lammers KM, Brigidi P, et al. Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology 2003; 124:1202-1209.
77. Mimura T, Rizzello F, Herwig U, Poggioli G, Schreiber S, Talbot IC, et al. Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut 2004; 53:108-114.
78. Shen B, Brzezinski A, Fazio VW, Remzi FH, Achkar JP, Bennett AE, et al. Maintenance therapy with a probiotic in antibiotic-dependent pouchitis: experience in clinical practice. Aliment Pharmacol Ther 2005; 22:721-728.
79. Kuisma J, Mentula S, Jarvinen H, Kahri A, Saxelin M, Farkkila M. Effect of Lactobacillus rhamnosus GG on ileal pouch inflammation and microbial flora. Aliment Pharmacol Ther 2003; 17:509-515.
80. Laake KO, Bjorneklett A, Aamodt G, Aabakken L, Jacobson M, Bakka A, et al. Outcome of four weeks' intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis. Scand J Gastroenterol 2005; 40:43-51.
81. Miglioli M, Barbara L, Di FG, Gozzetti G, Lauri A, Paganelli GM, et al. Topical administration of 5-aminosalicylic acid: a therapeutic proposal for the treatment of pouchitis. N Engl J Med 1989; 320:257.
82. Sambuelli A, Boerr L, Negreira S, Gil A, Camartino G, Huemos S, et al. Budesonide enema in pouchitis-a double-blind, double-dummy, controlled trial. Aliment Pharmacol Ther 2002; 16:27-34.
83. Gionchetti P, Rizzello F, Venturi A, Ferretti M, Brignola C, Peruzzo S, et al. Long-term efficacy of bismuth carbomer enemas in patients with treatment-resistant chronic pouchitis. Aliment Pharmacol Ther 1997; 11:673-678.
84. De OJ, Vilar L, Castellote J, Sanchez SR, Pares D, Biondo S, et al. Immunodulation with tacrolimus (FK506): results of a prospective, open-label, noncontrolled trial in patients with inflammatory bowel disease. Rev Esp Enferm Dig 2003; 95:465-464.
85. Baumgart DC, Wiedenmann B, Dignass AU. Rescue therapy with tacrolimus is effective in patients with severe and refractory inflammatory bowel disease. Aliment Pharmacol Ther 2003; 17:1273-1281.
86. Winter TA, Dalton HR, Merrett MN, Campbell A, Jewell DP. Cyclosporin A retention enemas in refractory distal ulcerative colitis and 'pouchitis'. Scand J Gastroenterol 1993; 28:701-704.
87. Viscido A, Habib FI, Kohn A, Papi C, Marcheggiano A, Pimpo MT, et al. Infliximab in refractory pouchitis complicated by fistulae following ileoanal pouch for ulcerative colitis. Aliment Pharmacol Ther 2003; 17:1263-1271.
88. Joelsson M, Andersson M, Bark T, Gullberg K, Hallgren T, Jiborn H, et al. Allopurinol as prophylaxis against pouchitis following ileal pouch-anal anastomosis for ulcerative colitis. A randomized placebo-controlled double-blind study. Scand J Gastroenterol 2001; 36:1179-1184.
89. Clausen MR, Tvede M, Mortensen PB. Short-chain fatty acids in pouch contents from patients with and without pouchitis after ileal pouch-anal anastomosis. Gastroenterology 1992; 103:1144-1153.
90. Simchuk EJ, Thirlby RC. Risk factors and true incidence of pouchitis in patients after ileal pouch-anal anastomoses. World J Surg 2000; 24:851-856.
91. Wischmeyer P, Pemberton JH, Phillips SF. Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. Mayo Clin Proc 1993; 68:978-981.
92. Shen B, Lashner BA, Bennett AE, Remzi FH, Brzezinski A, Achkar JP, et al. Treatment of rectal cuff inflammation (cuffitis) in patients with ulcerative colitis following restorative proctocolectomy and ileal pouch-anal anastomosis. Am J Gastroenterol 2004; 99:1527-1531.
93. Keighley MR, Grobler S, Bain I. An audit of restorative proctocolectomy. Gut 1993; 34:680-684.
94. O'Kelly TJ, Merrett M, Mortensen NJ, Dehn TC, Kettlewell M. Pouch-vaginal fistula after restorative proctocolectomy: aetiology and management. Br J Surg 1994; 81:1374-1375.
95. Keighley MR, Grobler SP. Fistula complicating restorative proctocolectomy. Br J Surg 1993; 80:1065-1067.
96. Groom JS, Nicholls RJ, Hawley PR, Phillips RK. Pouch-vaginal fistula. Br J Surg 1993; 80:936-940.
97. Marcello PW, Roberts PL, Schoetz DJ Jr, Coller JA, Murray JJ, Veidenheimer MC. Long-term results of the ileoanal pouch procedure. Arch Surg 1993; 128:500-503.
98. Senapati A, Tibbs CJ, Ritchie JK, Nicholls RJ, Hawley PR. Stenosis of the pouch anal anastomosis following restorative proctocolectomy. Int J Colorectal Dis 1996; 11:57-59.
99. Kelly KA, Pemberton JH, Wolff BG, Dozois RR. Ileal pouch-anal anastomosis. Curr Probl Surg 1992; 29:57-131.
100. Scott NA, Pemberton JH, Barkel DC, Wolff BG. Anal and ileal pouch manometric measurements before ileostomy closure are related to functional outcome after ileal pouch-anal anastomosis. Br J Surg 1989; 76:613-616.
101. Johnson MW, Dewar DH, Ciclitira P, Forbes A, Nicholls RJ, Bjarnason I. Use of fecal lactoferrin to diagnose irritable pouch syndrome: a word of caution. Gastroenterology 2004; 127:1647-1648.
102. Pescatori M, Manhire A, Bartram CI. Evacuation pouchography in the evaluation of ileoanal reservoir function. Dis Colon Rectum 1983; 26:365-368.
103. Dozois RR. Restorative proctocolectomy and ileal reservoir. Mayo Clin Proc 1986; 61:283-286.
104. Klas J, Myers GA, Starling JR, Harms BA. Physiologic evaluation and surgical management of failed ileoanal pouch. Dis Colon Rectum 1998; 41:854-861.
105. Iwama T, Kamikawa J, Higuchi T, Yagi K, Matsuzaki T, Kanno J, et al. Development of invasive adenocarcinoma in a long-standing diverted ileal J-pouch for ulcerative colitis: report of a case. Dis Colon Rectum 2000; 43:101-104.
106. Bentrem DJ, Wang KL, Stryker SJ. Adenocarcinoma in an ileal pouch occurring 14 years after restorative proctocolectomy: report of a case. Dis Colon Rectum 2003; 46:544-546.
107. Nyam DCNK, Wolff BG, Dozois RR, Pemberton JH, Mathison SM. Does the presence of a preileostomy closure asymptomatic pouch-anastomotic sinus tract affect the success of ileal pouch-anal anastomosis? J Gastrointest Surg 1997; 1:274-277.
108. Puthu D, Rajan N, Rao R, Rao L, Venugopal P. Carcinoma of the rectal pouch following restorative proctocolectomy. Report of a case. Dis Colon Rectum 1992; 35:257-260.
109. Rodriguez-Sanjuan JC, Polavieja MG, Naranjo A, Castillo J. Adenocarcinoma in an ileal pouch for ulcerative colitis. Dis Colon Rectum 1995; 38:779-780.
110. Stern H, Walfisch S, Mullen B, McLeod R, Cohen Z. Cancer in an ileoanal reservoir: a new late complication? Gut 1990; 31:473-475.
111. Sequens R. Cancer in the anal canal (transitional zone) after restorative proctocolectomy with stapled ileal pouch-anal anastomosis. Int J Colorectal Dis 1997; 12:254-255.
112. Barrett M, Schoetz D, Semple J, Rusin L, Cohen J, Roberts P. Long-term risk of neoplastic changes in ileoanal pouches in patients with ulcerative colitis. Dis Colon Rectum 1998; 41 (Suppl):Ref Type: Abstract.
113. Rotholtz NA, Pikarsky AJ, Singh JJ, Wexner SD. Adenocarcinoma arising from along the rectal stump after double-stapled ileorectal J-pouch in a patient with ulcerative colitis: the need to perform a distal anastomosis. Report of a case. Dis Colon Rectum 2001; 44:1214-1217.
114. Baratsis S, Hadjidimitriou F, Christodoulou M, Lariou K. Adenocarcinoma in the anal canal after ileal pouch-anal anastomosis for ulcerative colitis using a double stapling technique: report of a case. Dis Colon Rectum 2002; 45:687-691.
115. Laureti S, Ugolini F, d'Errico A, Rago S, Poggioli G. Adenocarcinoma below ileoanal anastomosis for ulcerative colitis: report of a case and review of the literature. Dis Colon Rectum 2002; 45:418-421.
116. Hyman N. Rectal cancer as a complication of stapled IPAA. Inflamm Bowel Dis 2002; 8:43-45.
117. Schmitt SL, Wexner SD, Lucas FV, James K, Nogueras JJ, Jagelman DG. Retained mucosa after double-stapled ileal reservoir and ileoanal anastomosis. Dis Colon Rectum 1992; 35:1051-1056.
118. Gilchrist KW, Harms BA, Starling JR. Abnormal rectal mucosa of the anal transitional zone in ulcerative colitis. Arch Surg 1995; 130:981-983.
119. Haray PN, Amarnath B, Weiss EG, Nogueras JJ, Wexner SD. Low malignant potential of the double-stapled ileal pouch-anal anastomosis. Br J Surg 1996; 83:1406.
120. Emblem R, Bergan A, Larsen S. Straight ileoanal anastomosis with preserved anal mucosa for ulcerative colitis and familial polyposis. Scand J Gastroenterol 1988; 23:913-919.
121. Veress B, Reinholt FP, Lindquist K, Lofberg R, Liljeqvist L. Long-term histomorphological surveillance of the pelvic ileal pouch: dysplasia develops in a subgroup of patients. Gastroenterology 1995; 109:1090-1097.
122. Remzi FH, Fazio VW, Delaney CP, Preen M, Ormsby A, Bast J, et al. Dysplasia of the anal transitional zone after ileal pouch-anal anastomosis: results of prospective evaluation after a minimum of ten years. Dis Colon Rectum 2003; 46:6-13.
123. Stahlberg D, Lofberg R. Underlying cholangiocarcinoma in a patient with high-grade dysplasia in the pelvic pouch. Inflamm Bowel Dis 1999; 5:150-151.
124. Gullberg K, Stahlberg D, Liljeqvist L, Tribukait B, Reinholt FP, Veress B, et al. Neoplastic transformation of the pelvic pouch mucosa in patients with ulcerative colitis. Gastroenterology 1997; 112:1487-1492.
125. Thompson-Fawcett MW, Marcus V, Redston M, Cohen Z, McLeod RS. Risk of dysplasia in long-term ileal pouches and pouches with chronic pouchitis. Gastroenterology 2001; 121:275-281.
126. Giarnieri E, Giovagnoli MR, Montesani C, Nagar C, Pronio AM, Alderisio M, et al. Image analysis in multisample biopsy after ileal pouch-anal anastomosis. Anticancer Res 1996; 16 (5B):3207-3211.
127. Giebel GD, Sabiers H. Ileal pouch-anal anastomosis for ulcerative colitis and polyposis coli: is the risk of carcinoma formation conclusively averted? Eur J Surg Oncol 1996; 22:372-376.
128. Setti-Carraro P, Ritchie JK, Wilkinson KH, Nicholls RJ, Hawley PR. The first 10 years' experience of restorative proctocolectomy for ulcerative colitis. Gut 1994; 35:1070-1075.
129. Sarigol S, Wyllie R, Gramlich T, Alexander F, Fazio V, Kay M, et al. Incidence of dysplasia in pelvic pouches in pediatric patients after ileal pouch-anal anastomosis for ulcerative colitis. J Pediatr Gastroenterol Nutr 1999; 28:429-434.